Clinical trials: Cognition Disorder
Physical Disability, Cognitive Dysfunction
Study on Cardiovascular Health, Nutrition and Physical Functioning in Older Adults in Spain
Population aging makes it necessary to identify factors related to unhealthy aging. The purpose of this study is to examine the association between ideal cardiovascular health, diet and other lifestyles and biological risk…
- Trial name
- Sen-ENRICAII (NCT03541135)
- Where
- Spain
- Volunteers
- 4,000 people
- Sponsor
- Universidad Autonoma de Madrid
Fatigue
Sleep and Training Aspects in Dialysis Fatigue - Exercise Intervention
The purpose of the current study is to investigate whether changes in patients' sleep quality and quantity will be followed by improvements in parameters related to physical and mental fatigue in patients receiving hemodialysis…
- Trial name
- StandFirm (NCT01721551)
- Testing
- Exercise, Usual Treatment
- Where
- 3 sites in Greece
- Volunteers
- 50 people
- Sponsor
- University of Thessaly
Mild Cognitive Impairment, Alzheimer Disease
INTERCEPTOR Project: From MCI to Dementia
In the next years a number of phase 2-3 trials which utilize experimental drugs possibly disease modifying for Alzheimer Dementia will reach their conclusion.
- Trial name
- INTERCEPTOR (NCT03834402)
- Where
- Italy
- Volunteers
- 500 people
- Sponsor
- Catholic University of the Sacred Heart
Alcohol Dependence, Dependence
Screening for Alcohol-related Cognitive Impairments in Cirrhotic Patients
80% of patients with alcohol use disorders (AUD) present cognitive impairments, such as memory and executive functions. These disorders may have repercussions in addiction treatment by altering the patient's adherence to care.
- Conditions
- Alcohol Dependence, Dependence, Cognitive Impairments, Cirrhosis
- Trial name
- CirCo (NCT04490330)
- Testing
- questionnaire
- Where
- France
- Volunteers
- 1 people
- Sponsor
- Centre Hospitalier Universitaire, Amiens
Breast Cancer
Exercise and Cognitive (Brain) Function in Breast Cancer Patients Getting Chemotherapy After Breast Surgery
This study will primarily identify longitudinal associations between cardiorespiratory fitness (CRF) and cognitive function pre- (baseline) to post-chemotherapy (~3 months). This will be a prospective study of 50 BCS.
- Trial name
- NCT04616300
- Where
- Canada
- Volunteers
- 50 people
- Sponsor
- University of Toronto
Schizophrenia, Caffeine
The Impact of Caffeine on Cognition in Schizophrenia
Caffeine is the most used psychoactive drug in Canada, with regular consumption by 88% of the adult population, While rates of caffeine consumption are considered to be high in the general population, there is some evidence that…
- Trial name
- NCT02832401
- Testing
- Caffeine
- Where
- Canada
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Nova Scotia Health Authority
Schizophrenia, Nicotine Addiction
Effects of rTMS on Cigarette Smoking and Cognition in Schizophrenia
Cigarette smoking rates are extremely high in persons with schizophrenia and this increases the risk of disease and death due to tobacco-related disorders.
- Trial name
- rTMSsmokelab (NCT01523730)
- Testing
- Repetitive Transcranial Magnetic Stimulation (rTMS)
- Where
- Canada
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- Centre for Addiction and Mental Health
Cognitive Impairment, Dementia
Anticipating Decline and Providing Therapy
This pilot feasibility study will be a randomized control trial of usual care following Intensive Care Unit (ICU) discharge compared to the Anticipating Decline and Providing Therapy (ADAPT) screening and support intervention.
- Conditions
- Cognitive Impairment, Dementia, Post ICU Syndrome, Critical Illness
- Trial name
- ADAPT (NCT06182995)
- Testing
- Usual Care post-Intensive Care Unit (ICU), Anticipating Decline and Providing Therapy (ADAPT)
- Where
- United States
- Volunteers
- 109 people
- Sponsor
- Wake Forest University Health Sciences
Huntington's Disease, Parkinson's Disease
Treating Sleep/Wake Cycle Disturbances in Basal Ganglia Disorders With Ramelteon
The proposed study is a double-blind, placebo controlled pilot study of HD, PD, and DLB subjects with sleep disturbances. This study is designed to determine the effects of 4 weeks Ramelteon treatment on the sleep patterns of…
- Conditions
- Huntington's Disease, Parkinson's Disease, Dementia With Lewy Bodies, Sleep Disorders
- Trial name
- NCT00907595
- Testing
- Ramelteon
- Where
- United States
- Sponsor
- Massachusetts General Hospital
Cognition, Affect (Mental Function)
BiomeBakery Project
This study aims to investigate the chronic effects of prebiotic fibre-fortified functional bakery product on cognitive, affective, inflammatory, metabolic, and anthropometric outcomes in healthy adults aged 60-75 years with mild…
- Conditions
- Cognition, Affect (Mental Function), C Reactive Protein
- Trial name
- NCT06796712
- Testing
- Prebiotic fibre fortified bread roll, Regular bread roll
- Where
- United Kingdom
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- University of Reading
Mild Cognitive Impairment
Keeping on Course: A Communication-Focused Psychoeducational Program
The goal of Keeping on Course is to develop and test a psychoeducation program to provide dyads facing mild cognitive impairment (MCI) with communication skills and strategies that will establish or restore a sense of agency as…
- Trial name
- NCT05423912
- Testing
- Keeping on Course Program
- Where
- United States
- Volunteers
- 29 people
- Sponsor
- Emory University
Cognitive Dysfunction
Dexmedetomidine and Esmolol Early Post Operative Cognitive Dysfunction
Dexmedetomidine is a highly selective α2adrenoceptor agonist recently introduced to anesthesia that produces dose dependent sedation, anxiolysis, and analgesia (involving spinal and supraspinal sites) without respiratory…
- Trial name
- NCT03892512
- Testing
- Esmolol Hydrochloride, Dexmedetomidine
- Where
- Egypt
- Volunteers
- 58 people
- Sponsor
- Beni-Suef University
PCNSL, Brain Tumor
Neurocognitive Assessment CNSL and LGG
This study is to determine whether self-administered digital cognitive tests can serve as accurate and reliable alternatives to established neuropsychological tests for evaluating cognitive functioning in participants with…
- Conditions
- PCNSL, Brain Tumor, Cognitive Dysfunction, IDH Mutation
- Trial name
- NCT07710131
- Testing
- Digital Cognitive Assessment (TestMyBrain and Mobile Toolbox), Traditional Neuropsychological Testing, Quality of Life and Mood Questionnaires
- Volunteers
- 36 people
- Sponsor
- Dana-Farber Cancer Institute
Schizophrenia, Schizoaffective Disorder
Adapted Cognitive/Affective Remediation for Cannabis Misuse in Schizophrenia
This study will integrate and adapt a cognitive remediation (Cognitive Enhancement Therapy [CET]) and an affect regulation (Personal Therapy [PT]) intervention for 50 individuals with schizophrenia that misuse cannabis.
- Trial name
- NCT01292577
- Testing
- CET/PT, Treatment as Usual
- Where
- United States
- Volunteers
- 33 people
- Sponsor
- University of Pittsburgh
Stroke, Cognitive Decline
Polypill and RiscOMeter to Prevent StrOke and CogniTive ImpairmEnt (PROMOTE)
This study is a phase III, prospective, placebo-controlled randomized clinical trial involving 8,518 subjects with low to moderate stroke risk, followed for 3 years in Brazil.
- Trial name
- PROMOTE (NCT05155137)
- Testing
- Drug Capsule (Valsartan + Amlodipine + Rosuvastatin), Stroke Riskometer
- Where
- 2 sites in Brazil
- Volunteers
- 8,518 people
- Sponsor
- Hospital Moinhos de Vento
Alzheimer Disease, Occupational Therapy
Quality-of-Life-and-Cognitive-Oriented Rehabilitation Through the NeuronUP in Alzheimer's Disease
Introduction: New technologies are a support in the rehabilitation of users. The therapeutic approach to cognitive rehabilitation encompasses a variety of techniques, among which traditional occupational therapy stands out.
- Conditions
- Alzheimer Disease, Occupational Therapy, Quality of Life, Cognitive Impairment
- Trial name
- NCT06499272
- Testing
- Conventional occupational therapy sessions + NeuronUP, Conventional occupational therapy sessions
- Where
- Spain
- Volunteers
- 35 people
- Sponsor
- Universidad Rey Juan Carlos
Rehabilitation, Stroke
Tele-rehabilitation for Cognitive Disorders
The aim of the study is to evaluate whether a computer-based cognitive treatment delivered via tele-rehabilitation produces an improvement in cognitive functioning comparable to the improvement achievable through the same…
- Conditions
- Rehabilitation, Stroke, Telerehabilitation, Telemedicine
- Trial name
- NCT06795672
- Testing
- Telerehabilitation, Traditional in-person rehabilitation.
- Where
- Italy
- Volunteers
- 23 people
- Sponsor
- Universita di Verona
Neurodevelopmental Disorders
EC Brain Program for Children With Special Education Needs
Children with special education needs (SEN) (e.g., autism, attention-deficit/hyperactivity disorder, dyslexia) who are studying in the mainstream primary schools are commonly found to have difficulties in learning school…
- Trial name
- NCT05428657
- Testing
- EC Brain After-school Program, conventional intervention
- Where
- 3 sites in China, Hong Kong
- Volunteers
- 328 people
- Sponsor
- Chinese University of Hong Kong
Schizophrenia, Cognition
Transcranial Direct Current Stimulation (tDCS) As A Treatment For Cigarette Craving and Cognitive Deficits in Schizophrenic
This is a study of the effects of tDCS on smoking, craving for cigarettes, cognition, and psychiatric symptoms in schizophrenic patients who are current smokers or have a history of regular cigarette smoking.
- Conditions
- Schizophrenia, Cognition, Cigarette Smoking
- Trial name
- TDCSSCHIZ (NCT02128919)
- Testing
- tDCS
- Where
- United States
- Volunteers
- 33 people
- Sponsor
- Nathan Kline Institute for Psychiatric Research
Alzheimer Disease, Cognitive Impairment
Coaching for Cognition in Alzheimer's (COCOA)
One major study objective is, using 2 study arms (data-driven health coaching plus RC vs. RC only), to evaluate the efficacy of data-driven health coaching. 'RC only' will serve as the control group.
- Trial name
- NCT03424200
- Testing
- Routine care, Coaching plus routine care
- Where
- United States
- Volunteers
- 54 people
- Sponsor
- Hoag Memorial Hospital Presbyterian