Clinical trials: Coenzyme Q10
Hepatocellular Carcinoma.
The Effects of Vitamin B-6 and Coenzyme Q10 Status on Oxidative Stress, Antioxidant Capacities, and Inflammatory Responses in Patients With Liver Cancer
Carcinoma is the leading cause of worldwide. Hepatocellular carcinoma (HCC) is the second cause of cancer mortality in Taiwan. Vitamin B-6 and coenzyme Q10 has been recognized as antioxidants and anti-inflammatory nutrients in…
- Trial name
- NCT01964001
- Testing
- Vitamin B-6, Coenzyme Q10, Vitamin B-6+Coenzyme Q10
- Where
- Taiwan
- Volunteers
- 71 people
- Sponsor
- Taichung Veterans General Hospital
Healthy
Pharmacokinetic Study on Three Formulations of Coenzyme Q10 With Different Carriers
Coenzyme Q10 (CoQ10) is a vitamin-like substance produced in all living human cells and naturally occurring in dietary sources. In addition to being responsible for the synthesis of adenosine triphosphate (ATP), a major source of…
- Trial name
- NCT04035525
- Testing
- MaxSimil® fish oil + CoQ10, Rice bran oil + CoQ10, CoQ10 as powder form
- Where
- Canada
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Mélanie Plourde
Cyclic Vomiting Syndrome
The Use of L-Carnitine And CoQ10 Supplements In the Treatment of Cyclic Vomiting Syndrome (CVS)
This is a study with the principle goal being to learn about the use of L-Carnitine and CoQ10, two vitamin supplements that are currently being used to treat Cyclic Vomiting Syndrome, largely initiated by parents.
- Trial name
- NCT00728104
- Where
- United States
- Sponsor
- Medical College of Wisconsin
Hypercholesterolemia, Physical Performance
CoQ10 in Statin-associated Asthenia
This was a double-blind, randomized, placebo-controlled clinical study aiming to assess the effects of supplementation with CoQ10 phytosome on physical performance in older adults with self-reported statin-associated asthenia.
- Trial name
- NCT06391606
- Testing
- Coenzyme Q10
- Where
- Italy
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Bologna
Cardiovascular Diseases, HMG COA Reductase Inhibitor Adverse Reaction
Exercise-induced Muscle Damage in Statin Users
Rationale: Combining statin treatment and physical activity is very effective for the prevention of cardiovascular diseases. Statins are well-tolerated by most patients, but may cause statin-associated muscle symptoms (SAMS) and…
- Conditions
- Cardiovascular Diseases, HMG COA Reductase Inhibitor Adverse Reaction, Muscle Damage
- Trial name
- NCT05011643
- Testing
- Moderate-intensity exercise
- Where
- Netherlands
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Radboud University Medical Center
Cardiovascular Disease, Diabetes Mellitus
Living With Statins - The Impact of Cholesterol Lowering Drugs on Health, Lifestyle and Well-being
Background Statins are cholesterol lowering drugs that are prescribed to lower the risk of cardio-vascular diseases. The use of statins has increased markedly and it is now one of the most prescribed drugs in the world.
- Trial name
- LIFESTAT (NCT02255682)
- Testing
- Simvastatin, Q10
- Where
- Denmark
- Volunteers
- 35 people
- Sponsor
- University of Copenhagen
Muscular Dystrophy, Duchenne
An Open-label Pilot Study of Coenzyme Q10 in Steroid-Treated Duchenne Muscular Dystrophy
This study will help to determine the safety and efficacy of the nutritional supplement Coenzyme Q10 when added to steroids as a treatment for Duchenne muscular dystrophy (DMD).
- Trial name
- NCT00033189
- Testing
- Coenzyme Q10
- Where
- 2 sites in United States
- Volunteers
- 15 people
- Sponsor
- Cooperative International Neuromuscular Research Group
Myelodysplastic Syndrome
The Effect of Combination Ultra Q10 and L-carnitine on the Course of Myelodysplastic Syndrome
The purpose of this study is determine whether combination Q10 , L-carnitine and multivitamin and mineral complex is effective in treatment of patients with low and intermidiate1-2 risk Myelodysplastic syndrome
- Trial name
- NCT02042482
- Testing
- Coenzyme Q10U, L-carnitine
- Where
- Israel
- Volunteers
- 40 people
- Sponsor
- Kaplan Medical Center
Patients With Type 2 Diabetes
A Randomised, Double-Blind, Placebo-Controlled Study Assessing the Effect of Fenofibrate, Coenzyme Q10 and Their co-Administration on Ventricular Diastolic Function in Patients With Type 2 Diabetes
The purpose of this study was to study the effect of different combinations of fenofibrate and coenzyme Q10 on ventricular diastolic function in patients with Type II diabetes
- Trial name
- NCT00703482
- Testing
- Fenofibrate/CoQ10
- Where
- 3 sites in Australia
- Volunteers
- 278 people
- Sponsor
- Solvay Pharmaceuticals
Type 1 Diabetes Mellitus
Effect of Coenzyme Q10 on Diabetic Children
Determine the effect of Coenzyme Q10 on random blood sugar and glycosylated haemoglobin
- Trial name
- NCT06361680
- Testing
- Coenzyme Q10 Cap/Tab as natural factors capsules or kirkman tablets
- Volunteers
- 100 people
- Sponsor
- Assiut University
Prostate Cancer, Uterine Cancer
COQ10 and Vitamin E for Off-Target Radiation Toxicity
The goal of this supportive care study is to learn if high-dose Vitamin E and CoQ10 in combination can reduce the negative sub-acute and chronic side effects of radiation to the pelvis in adults treated for prostate, uterine…
- Conditions
- Prostate Cancer, Uterine Cancer, Cervical Cancer, Anal Cancer
- Trial name
- NCT07668284
- Testing
- Coenzyme Q10 Cap/Tab, Vitamin E Cap/Tab
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- University of Nebraska
Covid19, Long Term Covid19
Coenzyme Q10 as Treatment for Long Term COVID-19
This study is a randomized, placebo-controlled, double-blinded, cross-over designed clinical trial investigating the effect of high-dose Coenzyme Q10 treatment in subjects with persisting symptoms more than 12 weeks af SARS-CoV-2…
- Trial name
- QVID (NCT04960215)
- Testing
- Coenzyme Q10
- Where
- Denmark
- Volunteers
- 121 people
- Sponsor
- Aarhus University Hospital
Cardiovascular Disease, Diabetes Mellitus
Living With Statins - Interventional Exercise Study
Background. Statins are cholesterol lowering drugs that are prescribed to lower the risk of cardio-vascular diseases. The use of statins has increased markedly and it is now one of the most prescribed drugs in the world.
- Trial name
- LIFESTAT (NCT02796378)
- Testing
- Training+Simvastatin+Q10
- Where
- Denmark
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Copenhagen
Molar, Third, Temporomandibular Joint Disorders
Evaluation the Effect of Coenzyme Q10 on Tissue Healing Process in Patients Undergoing Wisdom Tooth Extraction
The goal of this clinical trial is to asses the effect of Coenzyme Q10 administration in patients from any gender group who are older than 18 years old undergoing wisdom tooth extraction.
- Conditions
- Molar, Third, Temporomandibular Joint Disorders, Dry Socket, Coenzyme Q10
- Trial name
- NCT06452134
- Testing
- Coenzyme Q10 100 MG Oral Tablet
- Volunteers
- 70 people
- Sponsor
- Zahra Nejati
Myalgic Encephalomyelitis
Effect of CoQ10 Plus Selenium Supplementation on Clinical Outcomes and Biochemical Markers in ME/CFS (CoSeME Study)
In recent years, it has been suggested that nutritional deficiencies may be of causal relevance in individuals with ME/CFS. These include deficiencies of vitamins and trace elements.
- Trial name
- CoSeME (NCT05128292)
- Testing
- CoQ10 plus Selenium
- Where
- Spain
- Volunteers
- 42 people
- Sponsor
- Hospital Universitari Vall d'Hebron Research Institute
Coenzyme Q10 Pharmacokinetics
Pharmacokinetics of Different CoQ10 Formulations
The objective of this trial is to compare the bioavailability (AUC, Tmax, and Cmax) of different Coenzyme Q10 preparations in healthy adults.
- Trial name
- NCT06151171
- Testing
- CoQ10
- Where
- Canada
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Factors Group of Nutritional Companies Inc.
Attention Deficit Hyperactivity Disorder
Efficacy of Combined Treatment With CoQ10 and Methylphenidate in Children With Attention Deficit Hyperactivity Disorder
The aim of this study is to evaluate the effects of nutritional supplement co-enzyme Q10 (CoQ10) on methylphenidate-treated ADHD children in a randomized, double-blinded, placebo-controlled prospective study.
- Trial name
- NCT02315651
- Testing
- Coenzyme Q10
- Where
- Israel
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Rabin Medical Center
Charcot Marie Tooth Disease
Effects of Coenzyme Q10 on Charcot-Marie-Tooth Disease
The object of this research is to test the effectiveness of Coenzyme Q10 (CoQ10) on symptoms of weakness, fatigue, and pain in persons with Charcot-Marie-Tooth disease (CMT).In this study we also intend to examine the impact of…
- Trial name
- NCT00541164
- Testing
- Coenzyme Q10
- Where
- United States
- Volunteers
- 23 people
- Sponsor
- Memorial Medical Center
Open Angle Glaucoma
CoQun Study - (COQUN): a Study to Evaluate the Effects of CoQun in Patients Affected by Open-angle Glaucoma
This is a randomized, parallel arm, multicenter, double-blind trial. Patients with POAG will be randomized 1:1 ratio to receive: Prostaglandin analogue (PGA) monotherapy + CoQun® (Arm A) Prostaglandin analogue (PGA) monotherapy +…
- Trial name
- CoQun (NCT03611530)
- Testing
- Coqun® ophthalmic solution
- Where
- Italy
- Volunteers
- 111 people
- Sponsor
- Mario Negri Institute for Pharmacological Research
Oxidative Stress, Inflammation
CoQ10 Biomarker Trial
The investigators believe that relieving the oxidative stress experienced by hemodialysis patients may help improve cardiovascular health.
- Conditions
- Oxidative Stress, Inflammation, Endothelial Dysfunction
- Trial name
- NCT01408680
- Testing
- Coenzyme Q10
- Where
- United States
- Volunteers
- 66 people
- Sponsor
- University of Washington