Clinical trials: Cochlear Implant, open to volunteers
Sensorineural Hearing Loss, Hearing Loss
Quantification of Visually Evoked Cortical Potentials in Individuals With Hearing Loss
This research is being done to determine whether a test that measures a "Visual Evoked Potential" can be used in a new way for individuals that have hearing loss.
- Trial name
- NCT05107466
- Testing
- P300 Visually evoked potential
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Dartmouth-Hitchcock Medical Center
Hearing Loss
AI Noise Reduction in Phonak Hearing Aids
The purpose of this study is to determine if artificial intelligence- based noise reduction can offer objective improvement in hearing and speech perception for hearing impaired patients.
- Trial name
- NCT06743295
- Testing
- DEEPSONIC™ Deep Sound Optimized Neural Integrated Chip Artificial intelligence-based noise reduction
- Where
- United States
- Volunteers
- 500 people
- Sponsor
- Mayo Clinic
Cochlear Implantation, Robotics
Robotic-Assisted Versus Manual Electrode Array Insertion
Robotics-assisted electrode insertion overcomes many surgeon-related kinetic limitations such as insertion speed, tremor, drift, and lack of accurate force control.
- Trial name
- NCT06951594
- Testing
- Robotic
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Bruce J Gantz
Sensorineural Hearing Loss, Cochlear Implantation
Perceptual Adaptation Following Cochlear Implantation (Aim 3a)
The goal of this study is to study the adaptation process in newly implanted Single-Sided Deaf Cochlear Implant (SSD-CI) users. Subjects will use four frequency maps for the first month after CI activation.
- Conditions
- Sensorineural Hearing Loss, Cochlear Implantation, Perceptual Adaptation
- Trial name
- NCT07039435
- Testing
- Alternative Frequency Mapping
- Where
- United States
- Volunteers
- 22 people
- Sponsor
- NYU Langone Health
Tinnitus, Hearing Loss, Bilateral or Unilateral
Evaluating How a Tinnitus Implant Affects Tinnitus Loudness in Adults With Chronic Tinnitus and Varying Levels of Hearing Loss
This study will test an experimental Tinnitus Implant System that consists of a cochlear implant, sound processor and programming software.
- Conditions
- Tinnitus, Hearing Loss, Bilateral or Unilateral, Normal Hearing
- Trial name
- TINIS (NCT06641999)
- Testing
- Tinnitus Implant System
- Where
- 2 sites in Belgium, Netherlands
- Volunteers
- 16 people
- Sponsor
- Cochlear
Hearing Loss
Optimization of Hearing Performance in the Subject Implanted
In the past two decades, the selection criteria for cochlear implantation have been greatly relaxed so that about 60-70% of present cochlear implant (CI) candidates have significant residual hearing in their contralateral ear.
- Trial name
- OPERSA (NCT05325450)
- Testing
- Program A, Program B, Control
- Where
- France
- Volunteers
- 50 people
- Sponsor
- University Hospital, Toulouse
Sensorineural Hearing Loss, Bilateral
Comparison of Speech Understanding Between Tonotopy-based Fitting and Setting Based on Evolutionary Algorithms
Main objective: Compare speech recognition in noise with tonotopic setting (FS4T) and with tonotopic fitting modified by evolutionary algorithm (EAFS4T) in adult patients implanted for 6 months or more with a MED-EL cochlear…
- Trial name
- NCT06737185
- Testing
- EAFS4T: modification with evolutionary algorithm of tonotopic-based fitting
- Where
- France
- Volunteers
- 22 people
- Sponsor
- MED-EL Elektromedizinische Geräte GmbH
Profound Hearing Loss, Cochlear Implants
The Value Electrical Stapedial Reflex Thresholds (eSRTs) Cochlear Implant Mapping
One of the most significant challenges in cochlear implant programming, particularly for very young children and those with an associated pathologies, is the measurement of subjective comfort levels (= C-Subjective).
- Trial name
- eSRT (NCT06051006)
- Testing
- ESR and ECAP measurements, Device setting, Speech audiometry
- Where
- France
- Volunteers
- 30 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Deafness
Benefit of Connected Care for Cochlear Implant Management
Some 30 hospitals in France are accredited to manage cochlear implant (CI) activity, which represents around 1,800 new patients implanted per year and an estimated active file of over 20,000 patients.
- Trial name
- Connect IC (NCT07117968)
- Testing
- Standard-of-care, Experimental hybrid care pathway
- Volunteers
- 130 people
- Sponsor
- Hospices Civils de Lyon
Sensorineural Hearing Loss
Cochlear Implanted Listening Effort and Hearing Attention
Cochlear implant users perceive mainly sound amplitude modulation cues. Processing of these amplitude modulations can be subject to interferences, so that the perception of a modulation in a target sound can be impaired by a…
- Trial name
- EffICAtt (NCT04733950)
- Testing
- Forced choice psychoacoustic task for the evaluation of modulation detection performance and selective auditory attention. (for both arm), Measurement of the pupil diameter for the evaluation of listening effort during speech perception
- Where
- France
- Volunteers
- 170 people, healthy volunteers welcome
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Deafness
Investigating Auditory Processing in the Users of Auditory Brainstem and Cochlear Implants
This is a basic investigational research study conducted with hearing impaired adults and children who use cochlear implant or auditory brainstem implant (ABI) devices.
- Trial name
- NCT05810220
- Testing
- Electrode-Neural Interface
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- NYU Langone Health
Sensorineural Hearing Loss, Tinnitus
Effect of a Totally Implantable Cochlear Implant on Tinnitus Severity in Adults With Preoperative Tinnitus
The purpose of this study is to investigate the degree of benefit to tinnitus symptoms by using a Totally Implantable cochlear implant (TICI) in a group of patients who have moderate-to-severe tinnitus pre-operatively.
- Trial name
- EXCITE (NCT07893860)
- Testing
- Cochlear implant
- Where
- Spain
- Volunteers
- 14 people
- Sponsor
- Cochlear
Severe to Profound Sensorineural Hearing Loss
Correlations Between Subjective and Objective Responses to Cochlear Implant Stimulation
Cochlear implants have been used for several decades, with major technological advances. However, adjustment can be difficult for patients who have to get used to a new sound that is electrical rather than acoustic.
- Trial name
- CRSOSIC (NCT07371299)
- Testing
- Objective electrophysiological measures (eCAP, eABR, eSRT)
- Volunteers
- 60 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Cochlear Hearing Loss
MeasurIng and Restoring Auditory Awareness for Cochlear Implant Listeners in noisE
The goal of this interventional study is to describe how people with cochlear implants perceive the perceive speech in noise and their sound environment on adults who are native French speakers with typical hearing or with…
- Trial name
- MIRACLE (NCT06420921)
- Testing
- Speech in noise comprehension test, Objective tests of perception of ambient sound cues in noise, Subjective tests of perception of ambient sound cues in noise
- Where
- France
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Institut Pasteur
Hearing Loss
New Algorithms to Signal Processing for Speech Enhancement in Adult Cochlear Implant Recipients.
The purpose of this clinical investigation is to develop pre-processing strategies to enhance speech and reduce noise for CI listeners.
- Trial name
- PRESENCE-MU (NCT06100393)
- Testing
- Investigational Pre-Processing Algorithm (Sub A), Cochlear Limited standard-of-care pre-processing algorithms, Investigational Pre-Processing Algorithm (Sub B)
- Where
- 2 sites in Australia
- Volunteers
- 150 people
- Sponsor
- Cochlear
Sensorineural Hearing Loss, Bilateral, Bilateral Hearing Loss
Comparison in New Cochlear Implanted Subjects of a Tonotopy-based Bimodal Fitting and a Conventional Fitting
Main objective: For a bimodal fitting (hearing aid (HA) + cochlear implant (CI)): Comparison of a tonotopy based fitting strategy (TFS4) to a default fitting strategy (FS4) for the speech recognition in noise.
- Trial name
- NCT05955469
- Testing
- FS4 then TFS4 (cochlear implant), TFS4 then FS4 (cochlear implant)
- Where
- France
- Volunteers
- 20 people
- Sponsor
- MED-EL Elektromedizinische Geräte GmbH
Cochlear Implant Users
Assessment of a Method to Improve Cochlear Implant Users' Speech Perception in Noisy Environments While Maintaining Their Ability to Determine Where a Sound Originates From
The goal of this clinical trial is to determine if a new algorithm can improve speech perception for cochlear implant users. The main questions it aims to answer [is/are]: Does the algorithm improve speech perception in noisy…
- Trial name
- NCT07323862
- Testing
- Modifying audio input for cochlear implant processor
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- University of Illinois at Urbana-Champaign
Sensorineural Hearing Loss, Bilateral
Comparison in New Cochlear Implanted Subjects of a Tonotopy-based Bimodal Fitting With or Without Synchronization
Main objective: For a bimodal fitting (hearing aid (HA) + cochlear implant (CI)): Comparison of a tonotopy based fitting strategy with synchronization between HA and CI (ABFS) to a tonotopy based fitting strategy without…
- Trial name
- NCT05898659
- Testing
- ABFnoS then ABFS (Cochlear implant), ABFS then ABFnoS (Cochlear implant)
- Where
- France
- Volunteers
- 20 people
- Sponsor
- MED-EL Elektromedizinische Geräte GmbH
Cochlear Implant
Tissue Growth Characterization for Cochlear Implant Users
It is known from post-mortem histological studies that a significant portion of individuals who undergo cochlear implantation (CI) have scar tissue form around the implanted electrode array over time.
- Trial name
- NCT04320251
- Testing
- cochlear implant revision surgery
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- Vanderbilt University Medical Center
Vestibular Schwannoma, Hearing Loss
Cochlear Implantation After Gamma Knife Radiosurgery with EABR and Correlation to Postoperative Hearing Results - a Pilot Study
Patients undergoing cochlear implantation after radio surgery for vestibular schwannoma will be included in the study. Patients will undergo preoperative and intraoperative eABR measurement.
- Trial name
- NCT03745534
- Testing
- eABR
- Where
- Austria
- Volunteers
- 8 people
- Sponsor
- Christoph Arnoldner