Clinical trials: Coccidioidomycosis Infection
Toxoplasmosis, Rhd
Measuring the Prevalence of Toxoplasmosis and Its Socio-economic Consequences
The investigators propose a fast and inexpensive procedure to determine the prevalence of the Toxoplasmosis infection (Toxoplasma Gondii) in the general population, using response times in a cognitive task instead of costly…
- Trial name
- EconToxo (NCT05860998)
- Testing
- Presence of Toxoplasma gondii IgG Antibodies
- Volunteers
- 120 people
- Sponsor
- University of Zurich
Sporotrichosis, Chromomycosis
A Study on Rare Dermatological Infections Conducted at Three Major Reference Hospitals in Costa Rica.
In Costa Rica there are some descriptive studies of some of these rare infectious diseases (sporotrichosis, chromomycosis and mycetomas); however, there are no recent published reports.
- Conditions
- Sporotrichosis, Chromomycosis, Actinomycosis, Nocardiosis
- Trial name
- NCT06523998
- Where
- 3 sites in Costa Rica
- Volunteers
- 95 people
- Sponsor
- Caja Costarricense de Seguro Social
Coccidioidomycosis, Valley Fever
SUBA-Itraconazole Therapy for Coccidioidomycosis Refractory or Intolerant to Fluconazole
The purpose of this study is to determine how safe, effective, and well tolerated a new investigational antifungal drug, SUBA-itraconazole, is for patients who have been previously treated with fluconazole and have had either an…
- Trial name
- SITRIS (NCT04809649)
- Testing
- SUBA-itraconazole
- Where
- United States
- Sponsor
- George R Thompson
Cerebral Toxoplasmosis
Study of a Cohort of Non-HIV Immunocompromised Patients With Toxoplasmosis at the Strasbourg University Hospital
Toxoplasmosis in HIV-positive individuals is well-studied and has a codified management protocol, which is not the case for other immunodeficiencies, except for recent recommendations in the context of hematopoietic stem cell…
- Trial name
- TOXO (NCT07299500)
- Where
- France
- Volunteers
- 30 people
- Sponsor
- University Hospital, Strasbourg, France
Cryptosporidiosis, HIV Infections
A 28-Day Study of Diclazuril in the Treatment of Cryptosporidiosis in Patients With AIDS
To evaluate the safety and efficacy of diclazuril capsules as a treatment for cryptosporidial related diarrhea in AIDS patients who have been treated in the double-blind study # JRD 64,433/1101 and have relapsed, or de-novo…
- Trial name
- NCT00002278
- Testing
- Diclazuril
- Where
- 3 sites in United States
- Sponsor
- Janssen, LP
Rift Valley Fever, Hemorrhagic Fevers, Viral
RVF and Other Emerging Infectious Diseases in East and Central Africa
Rift Valley fever (RVF), a disease transmitted from livestock (cattle, sheep, goats, camels) to humans more commonly occurs in the East and Central Africa (ECA) regions where more than 15 major epidemics affecting more than one…
- Trial name
- NCT05139524
- Testing
- Evidence of past or recent RVF exposure
- Where
- 10 sites in Democratic Republic of the Congo, Kenya and 2 more
- Volunteers
- 5,000 people, healthy volunteers welcome
- Sponsor
- Washington State University
Coccidioidomycosis
POS vs FLU for First Line Treatment of Coccidioidomycosis (Study P04558Am1)(COMPLETED)
To evaluate the safety of posaconazole (POS) in the treatment of coccidioidomycosis. Period A consisted of 2 blinded arms, posaconazole and fluconazole.
- Trial name
- NCT00423267
- Testing
- Posaconazole, Fluconazole
- Volunteers
- 16 people
- Sponsor
- Merck Sharp & Dohme LLC
Cryptosporidiosis, HIV Infections
Protocol For the Treatment of Cryptosporidiosis in AIDS Patients With Diclazuril (R64,433)
To evaluate the safety and efficacy of diclazuril capsules compared with placebo capsules as treatment of cryptosporidial related diarrhea in AIDS patients.
- Trial name
- NCT00002027
- Testing
- Diclazuril
- Where
- 3 sites in United States
- Volunteers
- 60 people
- Sponsor
- Janssen, LP
Cryptosporidium; Diarrhea, Cryptosporidiosis
Trial of Ceramic Water Filters to Reduce Cryptosporidium Infection in Kenya
The aim of the study is to examine the efficacy of ceramic water filters to reduce the burden of waterborne diarrheal illness among infants in selected villages in Kenya.
- Conditions
- Cryptosporidium; Diarrhea, Cryptosporidiosis, Communicable Diseases, Diarrheal Disease
- Trial name
- NCT01695304
- Testing
- Ceramic water filter
- Where
- Kenya
- Volunteers
- 227 people, healthy volunteers welcome
- Sponsor
- Centers for Disease Control and Prevention
Coccidioidomycosis
Safety and Pharmacokinetics of VT-1598
This is a Phase 1, randomized, double-blind, placebo-controlled, single ascending dose study in healthy adult subjects ages 18 - 45 years inclusive. It is designed to evaluate the safety and PK of single oral doses of VT-1598.
- Trial name
- NCT04208321
- Testing
- VT-1598
- Where
- United States
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Cryptosporidiosis, HIV Infections
Open-Label "Compassionate" Use Study of Spiramycin for the Treatment of Diarrhea Due to Chronic Cryptosporidiosis in Immunocompromised Patients
This protocol provides for the availability of spiramycin under compassionate-use conditions for the treatment of chronic diarrhea due to cryptosporidium in patients with a compromised immune system, thus deriving additional…
- Trial name
- NCT00002062
- Testing
- Spiramycin
- Where
- United States
- Sponsor
- Rhone-Poulenc Rorer
Coccidioidomycosis
To Find Effectiveness of Stretching Versus Soft Tissue Mobilization in Coccydynia in Postpartum Females
This research is to determine the effectiveness of stretching versus soft tissue mobilization in coccydynia patients.The main purpose of the study is the the development of evidence based therapeutic protocols for postpartum…
- Trial name
- NCT06913803
- Testing
- Stretching, Soft Tissue Mobilization
- Where
- Pakistan
- Volunteers
- 46 people
- Sponsor
- Superior University
HIV, PCP
Antiretroviral Drug Interaction Study in Volunteers With HIV
Background: People who are infected with the human immunodeficiency virus (HIV) are at risk of getting certain diseases. Two of these diseases are a type of pneumonia known as PCP and a brain infection called toxoplasmosis.
- Conditions
- HIV, PCP, Toxoplasmosis
- Trial name
- NCT01479361
- Testing
- Atovaquone 750 mg twice daily, Atovaquone 1500 mg twice daily
- Where
- United States
- Volunteers
- 36 people
- Sponsor
- National Institutes of Health Clinical Center (CC)
HIV, Malnutrition
Breast Milk Composition and HIV-exposed/Unexposed Early Infant Growth and Infectious Disease Events
The purpose of this study is to understand how breast milk may protect infants from infection and promote favorable immunological, growth and development outcomes.
- Conditions
- HIV, Malnutrition, Cryptosporidiosis
- Trial name
- NCT01699841
- Where
- Tanzania
- Volunteers
- 208 people, healthy volunteers welcome
- Sponsor
- Cornell University
Valley Fever, Coccidioidomycosis
Improving the Appearance of Skin and Hair in Patients Undergoing Valley Fever Treatment
This will be a multi-visit study that will take approximately 3 hours in total. Up to 200 subjects from the BUMC Valley Fever and BUMC Dermatology clinics will be enrolled in this study and assigned to one of three cohorts…
- Trial name
- NCT03618992
- Testing
- Cholesterol-containing moisturizers
- Where
- 2 sites in United States
- Volunteers
- 14 people
- Sponsor
- University of Arizona
Coccidioidal Meningitis
Olorofim in Early Coccidioidal Meningitis
This research study is being conducted to learn more about the use of olorofim in Coccidioidal (Cocci) meningitis, a rare but serious fungal infection that affects the brain and spinal cord.
- Trial name
- NCT07385638
- Testing
- olorofim
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- Fariba Donovan
Rift Valley Fever
Safety and Immunogenicity of a Candidate Rift Valley Fever Vaccine (RVF003)
The goal of this clinical trial is to learn if ChAdOx1 RVF, a candidate vaccine against RVF, provides an adequate immune response and determine its safety among Kenyan adults.
- Trial name
- RVF003 (NCT06799234)
- Testing
- ChAdOx1 RVF, Rabies Vaccine
- Where
- Kenya
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- University of Oxford
Toxoplasmosis
Prognosis of Disseminated and Cerebral Toxoplasmosis Hospitalized in Intensive Care in the Era of PCR Diagnosis
Toxoplasmosis is a common infection whose clinical severity can sometimes justify admission to intensive care, especially in immunocompromised patients.
- Trial name
- TOXIC (NCT06305468)
- Where
- France
- Volunteers
- 200 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Cryptosporidiosis, HIV Infections
A Study to Evaluate the Use of Nitazoxanide to Treat Cryptosporidiosis
The purpose of this study is to see if nitazoxanide (NTZ) can be used to treat AIDS patients suffering from cryptosporidiosis (diarrhea caused by the parasite Cryptosporidium).
- Trial name
- NCT00002158
- Testing
- Nitazoxanide
- Where
- United States
- Sponsor
- Romark Laboratories L.C.
Cryptosporidiosis
Transmission and the Respiratory Tract in Cryptosporidiosis
Cryptosporidium is an intestinal parasite that causes diarrhea in children and adults. In addition to infection of the stomach, this parasite can infect the respiratory system causing a cough and/or problems breathing.
- Trial name
- NCT00507871
- Where
- Uganda
- Volunteers
- 480 people
- Sponsor
- Tufts University