Clinical trials: Cocaine Use Disorder (CUD), open to volunteers
Cocaine Use Disorder (CUD), Cognitive Impairments
The Role of Potassium Channels in Working Memory Impairments of Chronic Cocaine Users
The study aims to address the neurobiological basis of cognitive impairments in chronic cocaine users by investigating the potential impact of an acute potassium channel blockade on working memory performance and other cognitive…
- Trial name
- POTCHICUD (NCT07532460)
- Testing
- 4-aminopyridine (4-AP)
- Where
- Switzerland
- Volunteers
- 40 people
- Sponsor
- Boris Quednow
Cocaine Use Disorder (CUD)
Examination of Transcranial Focused Ultrasound on Brain Activity in Adults With Cocaine Use Disorder
The investigators aim to examine the effect of transcranial focused ultrasound (tFUS) on brain activity and cocaine craving in adults with cocaine use disorder.
- Trial name
- NCT07852923
- Testing
- tFUS
- Where
- United States
- Volunteers
- 57 people
- Sponsor
- Mary Phillips, MD MD (Cantab)
Cocaine Use Disorder
Imaging CRF X NOP Interactions in CUD
This study uses [11C]NOP-1A positron emission tomography (PET) and a hydrocortisone challenge to image the interaction between nociceptive opioid peptide (NOP) receptors and cortisol/corticotrophin releasing factor (CRF) in…
- Trial name
- NCT05008146
- Testing
- Baseline [C-11]NOP-1A PET Scan, Hydrocortisone, Post-hydrocortisone [C-11]NOP-1A PET Scan
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Rajesh Narendran
Alcohol Use Disorder (AUD), Cocaine Use Disorder (CUD)
Web-based Alcohol- or Cocaine-specific Inhibition Training in Adolescents and Young Adults With Substance Use Disorder
Substance misuse is one of the most common risk factors for health problems and premature death among adolescents and young adults worldwide.
- Conditions
- Alcohol Use Disorder (AUD), Cocaine Use Disorder (CUD), Substance Use Disorder (SUD)
- Trial name
- WAIT-AYA (NCT07071779)
- Testing
- Substance-specific inhibition training, Control training
- Where
- Switzerland
- Volunteers
- 210 people
- Sponsor
- University of Bern
Cocaine Use Disorder (CUD)
Contingency Management Plus Deep Transcranial Magnetic Stimulation for the Treatment of Cocaine Use Disorder
The purpose of this study is to evaluate the effects of Contingency Management (CM)+transcranial magnetic stimulation (TMS) on treatment outcomes in individuals who are initial non-responders and to evaluate the effects of CM+TMS…
- Trial name
- NCT07490600
- Testing
- Contingency Management (CM), Transcranial Magnetic Stimulation (TMS) experimental
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- The University of Texas Health Science Center, Houston
Cocaine Use Disorder (CUD)
The Impact of Cobenfy Maintenance on Cocaine's Effects
The goal of this clinical trial is to learn if Cobenfy influences the effects of cocaine in people with cocaine use disorder. This trial will also provide information about the safety and tolerability of combining Cobenfy and…
- Trial name
- NCT07624227
- Testing
- Cobenfy
- Where
- United States
- Volunteers
- 32 people
- Sponsor
- Joshua A. Lile, Ph.D.