Clinical trials: Co-occurring Mental and Substance Use Disorders
Co-Occurring Disorders, Homelessness
Maintaining Independence and Sobriety Through Systems Integration, Outreach, and Networking
This study seeks to implement wrap around services for Veterans suffering from co-occurring mental illness and substance use and who are homeless.
- Conditions
- Co-Occurring Disorders, Homelessness, Substance Abuse Disorder, Mental Illness
- Trial name
- MISSION-HPACT (NCT02942979)
- Where
- United States
- Volunteers
- 108 people
- Sponsor
- VA Office of Research and Development
Mental Health Disorders, Substance Use Disorders
Supporting Treatment Access and Recovery Through Linkage and Support
This 3-year Hybrid Type 1 study will randomize 208 people with co-occurring substance use and mental health disorders (COD) referred from the Worcester Hub.
- Trial name
- STAR-LS (NCT05713695)
- Testing
- Full MISSION, Linkage Only Delivered by a Peer Specialist
- Where
- United States
- Volunteers
- 208 people
- Sponsor
- University of Massachusetts, Worcester
PTSD, Substance Use Disorders
Cognitive Behavioral Therapy (CBT) for PTSD in Veterans With Co-Occurring SUDs
With this research, the investigators hope to learn if cognitive behavioral therapy (CBT) for posttraumatic stress disorder (PTSD) works in people who have both PTSD and problems with drugs or alcohol.
- Trial name
- CBT (NCT01357577)
- Testing
- Cognitive behavioral therapy for PTSD
- Where
- 3 sites in United States
- Volunteers
- 129 people
- Sponsor
- VA Office of Research and Development
Posttraumatic Stress Disorder, Substance Use Disorders
Emotional Regulation in People With Co-occurring Posttraumatic Stress Disorder and Substance Use Disorder
The aim of this project is to look at emotional regulation in people with posttraumatic stress disorder (PTSD) and substance use disorder (SUD).
- Conditions
- Posttraumatic Stress Disorder, Substance Use Disorders, Emotional Regulation
- Trial name
- NCT05531318
- Testing
- Qualitative Interview
- Where
- United Kingdom
- Volunteers
- 28 people
- Sponsor
- King's College London
Alcohol Use Disorder, Opioid Use Disorder
Developing e-Covery, an App-based Intervention to Support Individuals With Co-occurring Problem Alcohol and Opioid Use
This project aims to improve the health of individuals engaged in co-occurring alcohol and opioid use by supporting the maintenance of behavior change initiated in substance use treatment.
- Trial name
- NCT05325788
- Testing
- e-Covery, Comparator Condition
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Yale University
Opioid-use Disorder
Response to Relapse in Office-Based Opioid Treatment Trial
In a sample of individuals with co-occurring OUD and mental disorders, the investigators plan to test two medications for opioid use disorder (MOUD) treatment protocols that involve differing approaches to the use of opioids and…
- Trial name
- RR-OBOT (NCT03812107)
- Testing
- Moderate Treatment Approach, Intensive Treatment Approach
- Where
- United States
- Volunteers
- 115 people
- Sponsor
- Boston Medical Center
Anxiety Disorder, Posttraumatic Stress Disorder
Integrated CBT to Improve Functioning in Veterans With Anxiety and Substance Use
Individual with anxiety and post-traumatic stress disorder often use alcohol in ways that could cause them harm. Treating both mental health concerns and alcohol use at the same time can help reduce difficulties engaging in…
- Conditions
- Anxiety Disorder, Posttraumatic Stress Disorder, Hazardous Drinking
- Trial name
- NCT04871100
- Testing
- Unified Protocol- Alcohol, Usual care
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- VA Office of Research and Development
Alcohol Use Disorder, Insomnia
Mobile App Intervention for Sleep Problems and Alcohol Use Among Veterans
The goal of this clinical trial is to test the preliminary efficacy of a brief mobile app targeting insomnia symptoms among veterans.
- Trial name
- NCT06487793
- Testing
- Enhanced Insomnia Coach, Sleep hygiene comparator
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- University of Southern California