Clinical trials: Clinical Practice Guidelines
Heart Failure, Heart Failure With Reduced Ejection Fraction
Evaluating Strategies to Improve Guideline Directed Medical Therapy: The GDMT Research, Education & Assist Trial for Heart Failure Care
Heart failure with reduced ejection fraction (HFrEF) is associated with high mortality and adverse events (hospitalization or urgent outpatient visits for HF), along with diminished quality of life.
- Trial name
- GREAT-HF Care (NCT05990296)
- Testing
- Multiprong CDS with referral to pharmacist co-management, Multiprong CDS with GDMT order set, Focused education
- Where
- United States
- Volunteers
- 4,306 people
- Sponsor
- Geisinger Clinic
Acne Vulgaris
Effectiveness of Standard Therapy of Acne Vulgaris
This study was to evaluate the effectiveness of standard therapy for acne vulgaris (AV) based on the clinical practice guidelines (CPG) in Indonesia. The main questions it aims to answer were: 1.
- Trial name
- NCT05982613
- Where
- Indonesia
- Volunteers
- 724 people
- Sponsor
- Universitas Indonesia
Breast Cancer
Impact of OncoDoc2 on Guideline Compliance in the Management of Breast Cancer
The objective of the study is to evaluate how the use of OncoDoc2, a computerized guideline-based decision support system, could improve the compliance of multidisciplinary staff meeting decisions with local clinical practice…
- Trial name
- OncoDoc2 (NCT00728442)
- Testing
- ONCODOC LOGICIEL
- Where
- France
- Volunteers
- 816 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
PJI
Infection Consortium Study#1
In this study, the Sponsor wants to evaluate the performance and accuracy of the PJI Panel compared to the currently used multiple-criterion scoring systems for the diagnosis of PJI.
- Trial name
- NCT06153446
- Testing
- Synovasure® Comprehensive Infection Panel
- Where
- United States
- Volunteers
- 810 people
- Sponsor
- Zimmer Biomet
Diabetes, Prediabetes
Meta-analyses of the Effect of Tree Nuts on Glycemic Control and Features of the Metabolic Syndrome
Tree nuts (almonds, Brazil nuts, cashews, hazelnuts, macadamia nuts, pecans, pine nuts, pistachios and walnuts) are an important source of unsaturated fatty acids, vegetable protein, and fibre, as well as minerals, vitamins, and…
- Conditions
- Diabetes, Prediabetes, Dysglycemia, Overweight
- Trial name
- NCT01630980
- Testing
- Tree nuts
- Where
- Canada
- Volunteers
- 1 people
- Sponsor
- John Sievenpiper
Acute Deep Vein Thrombosis, Acute Pulmonary Embolism
Registry of Patients Prescribed Anticoagulation
The Gonda Vascular Center- Thrombophilia Clinic at Mayo Clinic in Rochester, Minnesota utilizes a standardized, guideline-directed, yet patient-oriented approach for treating patients diagnosed with venous thromboembolism…
- Trial name
- STAGPOR (NCT03504007)
- Where
- United States
- Volunteers
- 10,000 people
- Sponsor
- Mayo Clinic
GERD
Asociación Española de Gastroenterologia (Spanish Gastroenterology Association) Gastroesophageal Reflux Disease Guideline - Prospective Study
To evaluate symptomatic outcome and HRQoL in GERD patients treated following a new CP Guideline.
- Trial name
- Prospect (NCT00697008)
- Where
- 29 sites in Spain
- Volunteers
- 300 people
- Sponsor
- AstraZeneca
Contraception
Safety,Effectiveness and Acceptability of Sino-implant II in DR
A study to assess the contraceptive effectiveness of Sino-implant (II).
- Trial name
- NCT01594632
- Testing
- Jadelle, Sino-implant (II)
- Where
- Dominican Republic
- Volunteers
- 650 people, healthy volunteers welcome
- Sponsor
- FHI 360
Delirium
The ICU DElirium in Clinical PracTice Implementation Evaluation Study Screening and Treatment
Objective: Delirium is an important and frequently occurring complication in intensive care patients. However, screening and treatment of delirium is not in accordance with current national and international guidelines.
- Trial name
- iDECePTIvE (NCT01952899)
- Where
- Netherlands
- Volunteers
- 1,500 people, healthy volunteers welcome
- Sponsor
- Erasmus Medical Center
Insomnia
Insomnia in Primary Care
The goal of this clinical trial is to learn if training primary care providers on treatment of insomnia can improve insomnia symptoms in patients.
- Trial name
- NCT06575998
- Testing
- Training, Pro-active identification
- Where
- Netherlands
- Volunteers
- 485 people
- Sponsor
- Leiden University Medical Center
Contraception
PK of Depo SubQ Injected in the Upper Arm
A single-arm trial to demonstrate that Depo-SubQ Provera injected in the upper arm is adequate for effective contraception
- Trial name
- NCT01143207
- Testing
- Medroxyprogesterone acetate
- Where
- United States
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- FHI 360
Opioid Use
Nudging Providers to Curtail Dangerous Opioid Prescribing: A Trial to Investigate Mechanisms
Despite an enormous policy response, opioid prescribing remains well above historical levels and harms from opioids continue to mount.
- Trial name
- NCT04628832
- Testing
- PMP Use Mandate Letter, Prescribing Information Letter, Prescribing Information + PMP Use Mandate Letter
- Where
- 2 sites in United States
- Volunteers
- 12,000 people, healthy volunteers welcome
- Sponsor
- Columbia University
Obesity, Dyslipidemia
Meta-analyses of the Effect of Sucrose Versus High Fructose Corn Syrup on Cardiometabolic Risk
The rise in high fructose corn syrup (HFCS) consumption over the past 40 years since its introduction as a popular sweetener in the United States has led to much concern regarding its contribution to the rise in obesity (1)…
- Conditions
- Obesity, Dyslipidemia, Prediabetes, Dysglycemia
- Trial name
- NCT02702479
- Testing
- High Fructose Corn Syrup, Sucrose
- Where
- Canada
- Volunteers
- 1 people, healthy volunteers welcome
- Sponsor
- University of Toronto
Systemic Lupus Erythematosus
Multicomponent Strategy to Implement a Clinical Practice Guideline and Improve Health Outcomes in People With SLE
Principal objective: To produce scientific knowledge on the effectiveness and cost-effectiveness of a multicomponent intervention for knowledge transfer and implementing a Clinical Practice Guideline (CPG) for Systemic Lupus…
- Trial name
- NCT03537638
- Testing
- Multicomponent intervention
- Where
- Spain
- Volunteers
- 237 people
- Sponsor
- Servicio Canario de Salud
Perioperative Medicine, Diabetes (DM)
Adherence to Clinical Guidelines on Perioperative Diabetes Care
Patients who undergo major surgery face a 15-30% risk of serious adverse events, including a 1-5% mortality risk in the first month after surgery.
- Conditions
- Perioperative Medicine, Diabetes (DM), Diabetes Mellitus
- Trial name
- NCT07349199
- Where
- Denmark
- Volunteers
- 13,920 people
- Sponsor
- University Hospital Bispebjerg and Frederiksberg
Cardiovascular Risk Factors, Clinical Practice Guideline
Development, Implementation and Evaluation of the Impact of a Guideline in Clinical Practise for Cardiovascular Risk
The aim of this study is to evaluate the impact of a clinical guideline in cardiovascular risk, with a local adaptation model of the existing guidelines in clinical practise at present, of each of the different cardiovascular…
- Conditions
- Cardiovascular Risk Factors, Clinical Practice Guideline, Implementation Strategies, Primary Care
- Trial name
- NCT01270022
- Testing
- Implementation, dissemination
- Where
- Spain
- Sponsor
- Gerencia De Atencion Primaria Area 2 De Madrid
Tobacco Use Cessation, Tobacco Smoking
EHR-Based and Fax-Based Referral to a Tobacco Quitline: A Comparative Study
This study is designed to assess whether completely electronic, HIPAA-compliant, EHR-based, closed-loop referrals for tobacco cessation from primary care clinics to a state telephone tobacco quitline service can increase the…
- Trial name
- NCT02735382
- Testing
- Tobacco quitline EHR referral, Tobacco quitline Fax referral
- Where
- United States
- Volunteers
- 14,930 people
- Sponsor
- University of Wisconsin, Madison
Back Pain
Efficacy of Educating Physical Therapists in the Treatment of Patients With Nonspecific Chronic Low Back Pain
The aim of this trial is to investigate if patients treated by physical therapists who received an update on clinical practice guidelines and pain management have better outcomes than patients treated by physical therapists who…
- Trial name
- NCT02417402
- Testing
- Control, Trained
- Sponsor
- Universidade Cidade de Sao Paulo
Health Services Misuse, Physician's Practice Patterns
Primary Care Clinician Commitments to Choosing Wisely®
This pragmatic trial examines the uptake and effects of primary care clinician commitments to follow 3 Choosing Wisely® recommendations.
- Conditions
- Health Services Misuse, Physician's Practice Patterns, Guideline Adherence, Unnecessary Procedures
- Trial name
- NCT02247050
- Testing
- Commitment invitation
- Where
- 6 sites in United States
- Volunteers
- 45 people
- Sponsor
- University of Michigan
Psychotic Disorders, Obesity
Web-Based Delivery of MOVE! to Veterans With Serious Mental Illness (SMI)
Obesity and physical inactivity have reached epidemic proportions, resulting in increased rates of a variety of chronic diseases, increased risk of death, and substantial health care costs.
- Conditions
- Psychotic Disorders, Obesity, Health Behaviors
- Trial name
- Web-MOVE! (NCT00983476)
- Testing
- in-person MOVE! SMI, web-based MOVE! SMI
- Where
- United States
- Volunteers
- 276 people
- Sponsor
- VA Office of Research and Development