Clinical trials: Clinical Practice
Idiopathic Pulmonary Fibrosis
NICEFIT-ON: A Study Under Routine Clinical Practice in Taiwan to Observe the Long-term Outcome of People With Certain Types of Lung Disease (PF-ILD, SSc-ILD, IPF) Who Start Treatment With Nintedanib
To better understand the clinical characteristics of Idiopathic Pulmonary Fibrosis (IPF) / Systemic Sclerosis-associated-Interstitial Lung Disease (SSc-ILD)/ Progressive Fibrosing Interstitial Lung Disease (PF-ILD) patients…
- Trial name
- NCT04614441
- Testing
- OFEV®
- Where
- 26 sites in Taiwan
- Volunteers
- 214 people
- Sponsor
- Boehringer Ingelheim
Diabetes, Prediabetes
Meta-analyses of the Effect of Dietary Pulses on Acute Postprandial Metabolic Control
Dietary pulses (beans, peas, chickpeas, and lentils), more commonly known as "legumes", are generally recognized as healthy components of the diet.
- Conditions
- Diabetes, Prediabetes, Dysglycemia, Overweight
- Trial name
- NCT01605422
- Testing
- Dietary pulses
- Where
- Canada
- Volunteers
- 1 people
- Sponsor
- John Sievenpiper
Headache Disorders, Primary, Migraine With Aura
IndoProCaf Effervescent Tablets Effectiveness in Acute Treatment of Migraine and/or Episodic Tension-type Headache and Patients' Satisfaction With the Treatment in Routine Clinical Practice
Headaches are a common medical problem that physicians frequently encounter in their practice. One of key findings of The Atlas of Headache Disorders prepared by World Health Organization (WHO) is: headache disorders, including…
- Conditions
- Headache Disorders, Primary, Migraine With Aura, Migraine Without Aura, Tension-Type Headache
- Trial name
- PRESTO (NCT02115269)
- Where
- 30 sites in Kazakhstan, Ukraine
- Volunteers
- 759 people
- Sponsor
- Abbott
Crohn's Disease
Effectiveness and Safety in Patients With Crohn´s Disease in Clinical Routine
The purpose of this study was intended to evaluate the long-term safety and effectiveness of adalimumab in participants with Crohn's disease (CD) who are treated as recommended in the product label.
- Trial name
- NCT01083680
- Volunteers
- 4,107 people
- Sponsor
- AbbVie (prior sponsor, Abbott)
Rhinitis Allergic, Persistent
Evaluation of Safety of Levocetirizine in Routine Clinical Practice-non- Interventional Study
To evaluate over a period of 6 months the safety and the treatment satisfaction of newly prescribed levocetirizine in patients of age ≥ 2 years with persistent allergic rhinitis.
- Trial name
- NCT00598780
- Where
- United States
- Volunteers
- 7,870 people
- Sponsor
- UCB Pharma
Peripheral Artery Disease, Peripheral Arterial Occlusive Disease
The EasyFlype/EasyHiFlype Post Market Clinical Follow-up Study.
The Easy Flype Carbostent™ is a CE-marked nitinol self-expanding stent for superficial femoral artery (SFA) and Easy HiFlype Carbostent™is a CE-marked nitinol self-expanding stent for iliac vessels.
- Trial name
- NCT05616169
- Testing
- Easy Flype/EasyHiFlype
- Where
- 2 sites in Italy
- Volunteers
- 52 people
- Sponsor
- CID S.p.A.
Hodgkin's Disease
Hodgkin Lymphoma Molecular Profiling and Clinical Outcomes in U.S. Community Oncology Practices
The purpose of this study is to gather data on patients diagnosed with and treated for classical Hodgkin Lymphoma (cHL). It aims to closely observe how treatment for cHL is rendered, as well as assess the outcome of those…
- Trial name
- NCT02856646
- Where
- United States
- Volunteers
- 290 people
- Sponsor
- Bristol-Myers Squibb
Breast Neoplasms
A Study of Trastuzumab Subcutaneous in Participants With Human Epidermal Growth Factor Receptor-2 (HER2) Positive Early Breast Cancer
This observational study will evaluate the efficacy, safety, tolerability and participant reported quality of life of trastuzumab (Herceptin) subcutaneous (SC) therapy in participants with HER2-positive early breast cancer in…
- Trial name
- HerSCin (NCT01959386)
- Testing
- Trastuzumab
- Where
- Germany
- Volunteers
- 1,006 people
- Sponsor
- Hoffmann-La Roche
Metastatic Melanoma
A Study to Compare How Effective is Encorafenib Plus Binimetinib in Real-world and Clinical Trial Settings
Brief summary The purpose of this study is to compare how effective, encorafenib plus binimetinib is in the real-world and clinical trial settings.
- Trial name
- NCT05954546
- Testing
- Enco+bini
- Where
- United States
- Volunteers
- 275 people
- Sponsor
- Pfizer
Coronary Artery Disease, Peripheral Artery Disease
A Study to Collect Data on the Treatment Pattern of Xarelto + Acetylsalicylic Acid in the Routine Clinical Practice in Patients Who Are Suffering From a Condition That Narrows the Blood Vessels Supplying the Heart and / or a Condition That Most Commonly Narrows the Blood Vessel in the Legs
The study will focus on effectiveness and safety of rivaroxaban (Xarelto) when given together with acetylsalicylic acid (combination therapy) to patients suffering from coronary artery disease (a condition that affects the blood…
- Trial name
- XATOC (NCT04401761)
- Testing
- Rivaroxaban (BAY59-7939, Xarelto), Acetylsalicylic acid
- Where
- 10 sites in Belgium, China and 8 more
- Volunteers
- 3,189 people
- Sponsor
- Bayer
Diffuse Large B-cell Lymphoma
Chidamide in Patients With Recurrent and Refractory Diffuse Large b
A Multicenter, Prospective, Observational Clinical Protocol for Chidamide in Combination With Rituximab and Lenalidomide (cR2) in Real-world Practice in Patients With Relapsed/Refractory Diffuse Large B-cell Lymphoma
- Trial name
- NCT05690191
- Testing
- Chidamide, Lenalidomide, Rituximab
- Where
- China
- Volunteers
- 169 people
- Sponsor
- Second Affiliated Hospital of Soochow University
Healthy, Laughter
Effects of Laughter Yoga Practiced by Nursing Students Before Clinical Practice
Aim: We conducted this randomized controlled study to determine the effect of laughter yoga practiced by first year nursing students before clinical practice on their perceptions of stress and meaning of life.
- Conditions
- Healthy, Laughter, Stress
- Trial name
- NCT06042959
- Testing
- Laughter therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Manisa Celal Bayar University
Metastatic Pancreatic Cancer
Gemcitabine and Nabpaclitaxel in Metastatic Pancreatic Carcinoma.
Retrospective, multicenter study including pts with metastatic pancreatic cancer who started first-line treatment with napaclitaxel plus Gemcitabine between December 2013 and June 2015 according to the routine practice.
- Trial name
- ANICE-PaC (NCT03620461)
- Testing
- Gemcitabine - nabpaclitaxel
- Volunteers
- 210 people
- Sponsor
- Galician Research Group on Digestive Tumors
Orthodontic Pain (D013850), Orthodontic Patient Experience
Comparison of Different Debonding Techniques of Clear Aligner Attachments
The goal of this clinical trial is to compare two different methods for removing clear aligner attachments from tooth surfaces and to evaluate the pain levels and removal times associated with each method.
- Conditions
- Orthodontic Pain (D013850), Orthodontic Patient Experience, Orthodontic Aligners, Orthodontic
- Trial name
- NCT07259642
- Testing
- Adhesive removal plier followed by tungsten carbide bur, Tungsten carbide bur
- Where
- Turkey (Türkiye)
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Hacettepe University
Chronic Periodontitis
Clinical and Microbiological Effects of an Essential Oils Solution Used as an Adjunct to Daily Oral Hygiene Practices in Chronic Periodontitis Patients in Supportive Care
Chronic periodontitis is a common infectious disease characterized by progressive attachment loss and alveolar bone resorption eventually resulting in tooth loss.
- Trial name
- Listerine (NCT01195493)
- Testing
- Essential Oils solution, negative control solution
- Where
- Belgium
- Volunteers
- 50 people
- Sponsor
- University Hospital, Ghent
Adverse Effect, Renal Toxicity
Study of Adverse Renal Effects of Immune Checkpoints Inhibitors
Renal toxic events related to Immune Checkpoints Inhibitors therapy (Nivolumab, Pembrolizumab, Atezolizumab and Ipilimumab) have been recently reported. These were immune-allergic acute interstitial nephritis.
- Trial name
- ImmuNoTox(INT) (NCT03316417)
- Testing
- Renal Tolerance to Immunotherapy
- Where
- France
- Volunteers
- 353 people
- Sponsor
- Hospices Civils de Lyon
Postmenopausal Osteoporosis
Observational Study of Denosumab (Prolia®) in Postmenopausal Women With Osteoporosis
The main objective of this observational study was to describe medication-taking behavior of patients treated with denosumab for postmenopausal osteoporosis (PMO) at 12 and 24 months.
- Trial name
- NCT01668589
- Where
- 144 sites in Austria, Belgium and 2 more
- Volunteers
- 1,501 people
- Sponsor
- Amgen
Colitis, Ulcerative
A Study to Assess Clinical Effectiveness and Safety of Vedolizumab Intravenous in Real World Clinical Practice in Ulcerative Colitis (UC) Korean Participants
The purpose of this study is to assess the clinical effectiveness by the clinical response at 6 weeks and the safety of vedolizumab intravenous in UC Korean participants.
- Trial name
- NCT03535649
- Where
- 15 sites in South Korea
- Volunteers
- 105 people
- Sponsor
- Takeda
Secondary Immunodeficiency (SID)
A Study of Secondary Immunodeficiencies in Adults With Blood Cancers in Kazakhstan Who Have a Weakened Immune System (K-SIDE Study)
Some people with blood cancers (hematologic malignancies) develop a weakened immune system because of their condition or the medicines used to treat it. This is called a secondary immunodeficiency or SID.
- Trial name
- NCT07868107
- Testing
- No Intervention
- Where
- Kazakhstan
- Volunteers
- 200 people
- Sponsor
- Takeda
Patient Satisfaction, Nurse's Role
Effects of Nursing Patient Handover
This study was planned in a quasi-experimental design, focusing on the feasibility, evaluation, and implementation of patient handover between nurses, and the effect of interventions to increase their effectiveness on the…
- Trial name
- NCT06468631
- Testing
- Complex Nursing Intervention
- Where
- Turkey (Türkiye)
- Volunteers
- 369 people, healthy volunteers welcome
- Sponsor
- Kahramanmaras Sutcu Imam University