Clinical trials: Clinical Practice
Renal Carcinoma Metastatic, Kidney Neoplasms
Quality of Life Assessment in Daily Clinical Oncology Practice for Patients With Advanced Renal Cell Carcinoma
Physician mainly use RECIST progression-free survival (PFS) and NCI CTCAE safety as a guide to evaluate treatment efficiency. In contrast Health Related Quality of Life (HRQOL) assessment is often restricted to clinical trial.
- Conditions
- Renal Carcinoma Metastatic, Kidney Neoplasms, Renal Cancer
- Trial name
- QUANARIE (NCT03062410)
- Testing
- Electronic PRO in daily clinical practice
- Where
- 8 sites in France
- Volunteers
- 56 people
- Sponsor
- Centre Hospitalier Universitaire de Besancon
Adverse Drug Reaction (ADR)
The INTEGRATE Study: Integrated Pharmacogenetics, TDM and Active Pharmacovigilance as Innovative Tools for the Optimisation and Appropriateness of Drug Therapy
The primary goal of this observational study is to evaluate the feasibility of implementing a multidisciplinary approach based on pharmacogenetics, TDM (Therapeutic Drug Monitoring) and MedReview into the clinical practice in…
- Trial name
- INTEGRATE (NCT06822959)
- Testing
- Pharmacogenetics, TDM and MedReview
- Where
- 2 sites in Italy
- Volunteers
- 450 people
- Sponsor
- Direzione centrale salute, politiche sociali e disabilità
Asthma Control Level
Asthma Control and Clinical Practice in Hungary 2009
A prospective study led amongst pulmonologists. Patients asthma control level will be evaluated based on GINA guideline criteria. HRQoL measured by Visual analogue scale.
- Trial name
- NCT00900861
- Where
- 75 sites in Hungary
- Volunteers
- 3,000 people
- Sponsor
- AstraZeneca
Relapsing-Remitting Multiple Sclerosis
Effectiveness of Cladribine Tablets in Participants With Highly-active Relapsing Multiple Sclerosis (CAMELOT-MS)
The main purpose of this study was to investigate the effectiveness of cladribine tablets in a UK real-world setting.
- Trial name
- NCT04997148
- Where
- 8 sites in United Kingdom
- Volunteers
- 116 people
- Sponsor
- Merck Healthcare KGaA, Darmstadt, Germany, an affiliate of Merck KGaA, Darmstadt, Germany
Diabetes Mellitus, Type 2
A Research Study Looking at How Oral Semaglutide Works in People With Type 2 Diabetes in Israel, as Part of Local Clinical Practice
The purpose of the study is to collect information on how Rybelsus® works in people with type 2 diabetes and to see if Rybelsus® can lower their blood sugar levels.
- Trial name
- PIONEER REAL (NCT05443568)
- Testing
- Oral semaglutide
- Where
- Israel
- Volunteers
- 155 people
- Sponsor
- Novo Nordisk A/S
Bowel Preparation for Colonoscopy
Evaluation of the Quality of Bowel Cleansing in a Real Clinical Practice Setting
Publications of the use of bowel cleansers in usual clinical practice are lacking. Patient adherence to investigational products increases in the context of clinical trials.
- Trial name
- CALICOL (NCT02839824)
- Testing
- Bowel preparation
- Where
- Spain
- Volunteers
- 412 people
- Sponsor
- Casen Recordati S.L.
Coronavirus Disease (COVID-19)
Ain Shams University Experience: Clinical Determinants of Hospitalized COVID-19 Patients
COVID-19 as a novel disease, different disease patterns were observed worldwide, and many treatment plans were tried. So, it is important to investigate the Egyptian clinical characteristics and different factors that determine…
- Trial name
- NCT04584606
- Testing
- Lab workup (on admission and regularly during follow up).
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Ain Shams University
Burnout, Professional, Work Related Stress
Asynchronous Mindfulness Based Stress Reduction to Reduce Burnout in Licensed Clinical Social Workers
This is a quasi-experimental study that will examine whether mindfulness based stress reduction, adapted to an online learning management system, will reduce factors related to burnout in private practice licensed clinical social…
- Conditions
- Burnout, Professional, Work Related Stress, Quality of Life
- Trial name
- NCT05472935
- Testing
- Mindfulness Based Stress Reduction (MBSR)
- Where
- United States
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- State University of New York at Buffalo
Attention Deficit Disorder, Attention Deficit Hyperactivity Disorder
The Use of Lisdexamfetamine for Children Aged 7-13 With Attention Deficit Disorders
Aiming at improving clinical practice regarding the use of lisdexamfetamine for the treatment of ADHD in children, the investigators want to retrospectively map the clinical use of lisdexamfetamine at a specialised outpatient…
- Conditions
- Attention Deficit Disorder, Attention Deficit Hyperactivity Disorder, Hyperkinetic Disorder
- Trial name
- NCT04727476
- Testing
- Lisdexamfetamine
- Where
- Denmark
- Volunteers
- 413 people
- Sponsor
- Aarhus University Hospital
Patients With Asthma-COPD Overlap Syndrome (ACOS)
Non-interventional Study of COPD Patients With Asthma Overlap Syndrome in Viet Nam and Taiwan
The purpose of this study to determine the proportion and clinical characteristics of COPD patients with asthma symptoms (ACOS) and describe current practices in diagnosis and management in Viet Nam and Taiwan.
- Trial name
- NCT02878252
- Where
- 5 sites in Taiwan, Vietnam
- Volunteers
- 350 people
- Sponsor
- AstraZeneca
Chronic Kidney Diseases, Hypertension
Integrated Diagnosis and Treatment of CKD on Outcomes
Objective: To establish a study cohort and follow up of patients with CKD in our hospital, and evaluate the status of integrated CKD diagnosis and treatment according to guidelines in the real world, as well as the clinical…
- Conditions
- Chronic Kidney Diseases, Hypertension, Hyperglycemia, Hyperlipidemias
- Trial name
- NCT05242055
- Testing
- Integrated diagnosis and treatment for CKD
- Where
- China
- Volunteers
- 1,000 people
- Sponsor
- Capital Medical University
STERILITY
Assessment of the Effectiveness and Tolerability of Ovarian Hyperstimulation
The aim of the study is to assess the effectiveness of 5 mixed protocols of ovarian hyperstimulation with urinary gonadotrophins to achieve clinical pregnancy in females undergoing assisted reproductive techniques (IVF/ICSI)…
- Trial name
- DESCARTES (NCT01331720)
- Testing
- hMG-HP
- Where
- 14 sites in Spain
- Volunteers
- 279 people
- Sponsor
- Ferring Pharmaceuticals
Ventilator-Associated Events, Acute Kidney Injury
Effectiveness of an Evidence-Based Respiratory and Renal Care Training With Case-Based Discussion on Nurses' Clinical Reasoning, Knowledge & Practice, Nurse-Physician Collaboration and Mechanically Ventilated Patient Outcomes in a Tertiary-Level ICU in Bangladesh
This study will evaluate the effectiveness of an evidence-based respiratory and renal care training program combined with case-based discussion on nurses' clinical reasoning, knowledge \& practice, nurse-physician collaboration…
- Conditions
- Ventilator-Associated Events, Acute Kidney Injury, Clinical Reasoning
- Trial name
- NCT07796724
- Testing
- evidence-based respiratory and renal care training with case-based discussion
- Where
- Bangladesh
- Volunteers
- 140 people
- Sponsor
- Hiroshima University
Cataract, Lens Diseases
Correlations Between Lens Star and Phacoemulsification.
To assess correlations between lens star biometry parameters and phacoemulsification in clinical practice.
- Conditions
- Cataract, Lens Diseases, Lens Opacities
- Trial name
- NCT05290896
- Testing
- Phacoemulsification
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Benha University
Melioidosis
An Observational Study to Evaluate Clinical Characteristics of Adult Patients With Suspected or Confirmed Melioidosis
This is a prospective observational study to evaluate clinical characteristics, current practice and outcomes of adult patients (age ≥18 years) with suspected or confirmed melioidosis.
- Trial name
- NCT06089668
- Testing
- Observational Study
- Where
- 3 sites in Laos, Thailand
- Volunteers
- 200 people
- Sponsor
- AN2 Therapeutics, Inc
Epilepsy, Gingivitis
Air Polishing Effect on Biological, Clinical and Patient-reported Experience Among Epileptic and Non-epileptic Children
In epileptic and non Epileptic children, the full dentition of each patient was split into four quadrants, starting from the upper right quadrant (1) and moving clockwise until the lower right quadrant (4).
- Trial name
- NCT06144034
- Testing
- Air polishing with erythritol powder, Conventional treatment
- Where
- 2 sites in Jordan
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- King Abdullah University Hospital
Dyslipidemias, Diabetes Mellitus, Type 2
Use of Nutraceuticals in Clinical Practice
The aim of this study will be to evaluate the use of the nutraceutical with cardio-metabolic actions in clinical practice in addition to a Mediterranean diet scheme, normally recommended in the clinic.
- Conditions
- Dyslipidemias, Diabetes Mellitus, Type 2, Hypertension
- Trial name
- NCT04161859
- Testing
- Nutraceutical
- Where
- Italy
- Volunteers
- 387 people
- Sponsor
- University of Pavia
Any Condition Requiring Surgical Treatment Via Colectomy
ENSEAL® G2 Articulating Tissue Sealer in Laparoscopic Colectomy
The primary objective of this clinical study is to describe the initial clinical experience with ENSEAL® G2 Articulating Tissue Sealer in laparoscopic colectomy, quantifying and/or qualifying how its articulation feature enables…
- Trial name
- NCT02044770
- Where
- 3 sites in United States
- Volunteers
- 29 people
- Sponsor
- Ethicon Endo-Surgery
Non-small-cell Lung Cancer
Treatment and Biomarker Testing Patterns,Treatment Outcomes in a/m NSCLC With and Without Actionable Genomic Alterations
Planned study population consists of approximately 1500 adult patients with a/m NSCLC in Russia, in about 20 oncological centers (in each center it is expected to recruit about 75 patients) in different regions of Russia in order…
- Trial name
- NCT06245837
- Where
- 16 sites in Russia
- Volunteers
- 1,500 people
- Sponsor
- AstraZeneca
Urinary Catheter, Urinary Tract Infections
Sharklet Catheter Study
The aim of this study is to determine if the Sharklet catheter, with its unique coating, reduces infections in participants, when compared to a standard catheter.
- Trial name
- NCT02669342
- Testing
- Radiance™ Clear Sharklet® Silicone Foley Catheter, Silicone Foley Catheter
- Where
- Canada
- Volunteers
- 32 people
- Sponsor
- University of British Columbia