Clinical trials: Clinical Outcomes
Catheter Complications
Comparison of Clinical Outcomes of Mini Midline Catheters With Different Placement Sites: a Randomized Controlled Trial
Peripheral venous catheters are the most commonly used vascular access devices in healthcare today, including indwelling needles, mini-midline catheters, and medium-length venous catheters.
- Trial name
- NCT06106659
- Testing
- Mini Midline
- Where
- China
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- Sir Run Run Shaw Hospital
Asthma
A Study Evaluating Disease Characteristics and Outcomes in Participants With Asthma in Routine Clinical Practice
The main aim of the study to describe the characteristics of participants with asthma across the spectrum of disease severity, including sociodemographic and clinical characteristics, treatment and disease burden, biomarkers, and…
- Trial name
- AIRITY (NCT07556159)
- Testing
- Procedure: Investigational Procedures
- Where
- 71 sites in United States, Canada and 3 more
- Volunteers
- 2,500 people
- Sponsor
- Sanofi
Parastomal Hernia
Laparoscopic Parastomal Hernia Repair Using the Sandwich Technique:
This study focuses on improving the surgical repair of parastomal hernias (PSHs), which are a common complication for patients with stomas.
- Trial name
- APOLLO (NCT06791642)
- Testing
- Laparoscopic Parastomal Hernia Repair Using the Sandwich Technique
- Where
- Italy
- Volunteers
- 31 people
- Sponsor
- Azienda Sanitaria Locale Napoli 2 Nord
Vitamin D Deficiency, Vascular Calcification
Effects of Cholecalciferol on Osteoprotegerin Levels in Patients on Peritoneal Dialysis
Aim: To investigate whether cholecalciferol (4800 U/daily) or placebo for 16 weeks reduces proteins levels associated with vascular calcification (osteoprotegerin, osteopontin, osteocalcin) in patients treated with peritoneal…
- Conditions
- Vitamin D Deficiency, Vascular Calcification, Renal Insufficiency, End Stage Renal Failure on Dialysis
- Trial name
- NCT02598635
- Testing
- Cholecalciferol
- Where
- Mexico
- Volunteers
- 58 people
- Sponsor
- Instituto Nacional de Ciencias Medicas y Nutricion Salvador Zubiran
Hypertension
Telepharmacy on Patients With Arterial Hypertension
The goal of this clinical trial is to compare the effectiveness of a pharmaceutical care protocol via teleconsultation in the management of uncontrolled hypertension with pharmaceutical care carried out in elderly patients…
- Trial name
- CELESTE (NCT06108674)
- Testing
- Pharmaceutical care via telepharmacy and usual care, Pharmaceutical care in-person and usual care
- Where
- Brazil
- Volunteers
- 194 people
- Sponsor
- Federal University of Bahia
Pain From Free Gingival Graft
Patient Outcomes and Gingival Blood Flow Using Laser Doppler Flowmetry Following the Use of Episil on Free Gingival Graft Donor Sites
The hypothesis for the present study is that patient-based outcomes and gingival blood flow will be more favorable for the free gingival graft (FGG) donor sites being covered by the test wound dressing material episil compared to…
- Trial name
- NCT03350724
- Testing
- episil wound dressing, PeriAcryl90 wound dressing
- Where
- United States
- Volunteers
- 34 people
- Sponsor
- The University of Texas Health Science Center, Houston
Femoro Acetabular Impingement
Effect of Lower Limb Rotation on Clinical Outcomes After Arthroscopic Management in Patients With Symptomatic Femoroacetabular Impingement Syndrome
To determine The prevalence of abnormalities of femoral and acetabular versions and tibial torsion in symptomatic (FAI) Syndrome.
- Trial name
- NCT06420180
- Testing
- hip arthroscopy
- Volunteers
- 50 people
- Sponsor
- Al-Azhar University
COPD, Exacerbation Copd
Exacerbations and Their Outcomes International (EXACOS International)
The aim of this study is to quantify the burden of severe AECOPD in South Korea, by investigating the association between frequency of severe AECOPD and clinical and health-care utilization outcomes.
- Trial name
- NCT05750810
- Testing
- Severe exacerbation frequency
- Where
- South Korea
- Volunteers
- 3,477 people
- Sponsor
- Joon Young Choi
Tinnitus, Subjective, Sudden Deafness
The Study on Effect and Neural Network Mechanism of Transcranial Direct Current Stimulation for Sudden Deafness With Tinnitus
This clinical study is prospective, single-center, randomized, controlled, double-blind clinical trail, which entitled transcranial electrical stimulation for the treatment of acute tinnitus approved by Sun Yat-sen University…
- Conditions
- Tinnitus, Subjective, Sudden Deafness, Transcranial Direct Current Stimulation, Double-Blind Method
- Trial name
- NCT05964725
- Testing
- Receive traditional medical therapy and transcranial direct current stimulation
- Where
- China
- Volunteers
- 86 people
- Sponsor
- Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University
Stable Angina
Fractional FLow Reserve And IVUS for Clinical OUtcomes in Patients With InteRmediate Stenosis
To compare the safety and efficacy of FFR (fractional flow reserve)-guided percutaneous coronary intervention (PCI) strategy with IVUS (intravascular ultrasound [IVUS])-guided PCI in patients with intermediate coronary stenosis.
- Trial name
- FLAVOUR (NCT02673424)
- Testing
- FFR-guided stenting, IVUS-guided stenting
- Where
- 5 sites in China, South Korea
- Volunteers
- 1,700 people
- Sponsor
- Seoul National University Hospital
Fibromyalgia
Telerehabilitation in Patients With Fibromyalgia
Sixty-six FMS patients received the same exercise program for 8 weeks and divided, synchronous (n: 33), asynchronous (n: 33). Pain (Visual analog Scale, VAS), functional limitations and disabilities (Revised Fibromyalgia Impact…
- Trial name
- NCT06299527
- Testing
- Exercise Program
- Where
- Turkey (Türkiye)
- Volunteers
- 66 people
- Sponsor
- Marmara University
Multiple Sclerosis
Propionic Acid for Multiple Sclerosis: Safety and Benefits
The purpose of this study is to explore the long-term safety, tolerability, and clinical efficacy of propionic acid as an add-on therapy in multiple sclerosis (MS).
- Trial name
- Pro-MADAI (NCT07595081)
- Testing
- Propionic acid 1000 mg capsule
- Where
- Austria
- Volunteers
- 22 people
- Sponsor
- Salzburger Landeskliniken
Myelofibrosis
A Study to Assess Real-World Patient-Reported Outcomes With Fedratinib for Myelofibrosis Post-Ruxolitinib
The purpose of this study is to determine real-world patient-reported outcomes with fedratinib (FEDR) therapy for myelofibrosis (MF) in the real-world (RW) setting.
- Trial name
- NCT05665192
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- Bristol-Myers Squibb
Kidney Transplant
Observational Registry Study of Renal Transplant Patients
The MORE Observational Study follows real-world renal transplant patients with the data resolution of a monitored, prospective clinical trial for 5 years.
- Trial name
- MORE registry (NCT01284257)
- Where
- 8 sites in United States
- Sponsor
- Novartis Pharmaceuticals
Early Colorectal Cancer, Non-curative Endoscopic Resection
Clinical Outcomes After Non-curative Endoscopic Resection in Early Colorectal Cancer: A Multicenter Study
This multicenter study aims to evaluate clinical outcomes and optimize management strategies in patients with early colorectal cancer who undergo non-curative endoscopic resection.
- Trial name
- NCT07542171
- Testing
- Additional Surgery, Surveillance
- Where
- 3 sites in China
- Volunteers
- 400 people
- Sponsor
- Nanfang Hospital, Southern Medical University
Pulpotomized Primary Molars
Clinical Outcomes of Digital vs Prefab Crowns for Pulpotomized Primary Molars
NuSmile Zirconia crowns: Prefabricated pediatric Zirconia crowns offer an excellent alternative to full-coverage crowns when restoring deciduous teeth with a sizeable carious defect.
- Trial name
- NCT06733909
- Testing
- Restoration of Pulpotomized Primary Molars using NuSmile Zirconia crowns, Restoration of Pulpotomized Primary Molars using BioFlx crowns, Restoration of Pulpotomized Primary Molars using Digital VITA ENAMIC crowns (CAD/CAM blanks)
- Where
- Egypt
- Volunteers
- 102 people, healthy volunteers welcome
- Sponsor
- October University for Modern Sciences and Arts
Dementia With Lewy Bodies
Impact of Bosutinib on Safety, Tolerability, Biomarkers and Clinical Outcomes in Dementia With Lewy Bodies
This study evaluates the effect of Bosutinib (Bosulif,Pfizer®) in the treatment of patients with Dementia with Lewy Bodies. Half participants will receive 100 mg of Bosutinib , while the other half will receive placebo.
- Trial name
- NCT03888222
- Testing
- Bosutinib Oral Tablet
- Where
- United States
- Volunteers
- 26 people
- Sponsor
- Georgetown University
Pulp Disease, Dental, Pulp Necrosis
Chloramphenicol, Tetracycline, Zinc Oxide and Eugenol Paste (CTZ Paste) for Emergency Dental Treatment in Public Health Settings: A Randomized Trial
The treatment of pulpal diseases in primary teeth represents a significant challenge in public health, particularly in emergency dental care settings, where factors such as limited clinical time, low child cooperation, and…
- Conditions
- Pulp Disease, Dental, Pulp Necrosis, Pulp Therapy in Primary Molars, Primary Teeth
- Trial name
- CTZ- emergency (NCT07542639)
- Testing
- CTZ Paste, ZOE Pulpectomy
- Volunteers
- 110 people
- Sponsor
- University of Sao Paulo
Anal Fistula, Fistula in Ano
Impact of Preoperative Bowel Preparation on Healing Outcomes in FiLaC
Background: Fistula tract laser closure (FiLaC) has emerged as a sphincter-preserving treatment for anal fistula (AF). However, the optimal role of preoperative bowel preparation (BP) in enhancing postoperative outcomes remains…
- Conditions
- Anal Fistula, Fistula in Ano, Laser, Anal Fistula Surgery
- Trial name
- FiLaC-PREP (NCT07800065)
- Testing
- Bowel preparation before fistula laser closure (FiLaC) surgery
- Volunteers
- 100 people
- Sponsor
- Acibadem Kent Hospital
Coronary Artery Disease
SMART Trial Longitudinal Follow-Up:Off-Pump Versus On-Pump Coronary Artery Bypass Surgery
The purpose of this study is to determine completeness of revascularization, graft patency, clinical outcomes, health-related quality of life and costs in 200 initial trial participants at > 5 years post surgery who had heart…
- Trial name
- NCT00209053
- Testing
- Coronary Artery Bypass
- Where
- United States
- Volunteers
- 87 people
- Sponsor
- Emory University