Clinical trials: Clinical Decision Support
Emergency Service, Hospital, Social Determinants of Health
Predictive Modeling for Social Needs in Emergency Department Settings
The overall objective of this study is to support emergency department management of patients' health-related social needs. This study will measure the impact of a decision support system that informs clinicians about which…
- Trial name
- NCT06655974
- Testing
- Health-related social needs decision support system
- Where
- United States
- Volunteers
- 518,512 people, healthy volunteers welcome
- Sponsor
- Indiana University
Clinical Decision Support, Clinical Decision-making
Generative AI-Assisted Clinical Decision Support for Medical Intensive Care Unit Physicians
This pilot study evaluated the feasibility and usefulness of generative artificial intelligence (AI) as a clinical decision-support tool for physicians working in a medical intensive care unit.
- Trial name
- NCT07708155
- Testing
- Generative AI-Assisted Clinical Decision Support, Usual Clinical Information Resources
- Where
- South Korea
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Seoul National University Hospital
Critical Illness, Sepsis
Point-of-Care AI Assistance and Critical Care Outcomes: A Randomized Trial
This is a prospective, unmasked, randomized, multicenter clinical trial evaluating the impact of point-of-care large language model (LLM)-based decision support on diagnostic accuracy and clinical outcomes in adult medical…
- Conditions
- Critical Illness, Sepsis, Acute Respiratory Failure (ARF), Multi-organ Failure
- Trial name
- POC-AI-ICU (NCT07293078)
- Testing
- Point-of-care large language model decision support (ChatGPT-5)
- Where
- United States
- Volunteers
- 1,000 people
- Sponsor
- MetroWest Artificial Intelligence Research Workgroup
Healthcare
Clinical and Economic Impact of an Electronic Medical Record Interfaced Decision Support System Reinforced With Patient Specific Pharmacogenetic Data for Minimizing Severe Drug-Drug Interactions
Leumit Health Services, an health maintenance organization operating in Israel, will incorporate a web-based, decision support system for handling drug-drug interactions and drug information, termed DDI+ reinforced with patient…
- Trial name
- DDI+ (NCT01765621)
- Testing
- DDI+ System and Pharmacogenetic Data
- Where
- Israel
- Volunteers
- 973 people, healthy volunteers welcome
- Sponsor
- Leumit Health Services
Attention Deficit-hyperactivity Disorder
Improving the Medication Management of Patients With Attention-Deficit Hyperactivity Disorder
The specific aim of this cluster-randomized (site) comparative effectiveness research study is to determine whether children who are (1) 5-12 years of age, (2) cared for in ePROS practices or clinics using an electronic health…
- Trial name
- ePROS (NCT01769300)
- Testing
- Clinical decision support for medication titration
- Where
- United States
- Sponsor
- American Academy of Pediatrics
Rare Disorders, Rare Diseases
Artificial Intelligence for General and Rare Disease Diagnosis
A multicentre, randomised diagnostic accuracy study to evaluate whether the GENESIS AI diagnostic support system can improve diagnostic accuracy and efficiency for physicians managing real-world clinical general and rare cases.
- Conditions
- Rare Disorders, Rare Diseases, Generalist AI
- Trial name
- NCT07625436
- Testing
- AI-Assisted Diagnosis
- Where
- 11 sites in China
- Volunteers
- 243 people, healthy volunteers welcome
- Sponsor
- Peking Union Medical College Hospital
Differential Diagnosis, Diagnostic Accuracy
Evaluation of One-Shot Vision Differential Diagnosis (OSVDE) and Multi-Step Conversational Non-Inferiority (MSCNE) in AI Medical Interviewing
This study evaluates the diagnostic performance of a multimodal artificial intelligence (AI) system (AIMD.1) using de-identified medical images and semi-synthetic patient simulations.
- Trial name
- OSVDE-MSCNE (NCT07470463)
- Testing
- AI Diagnostic System (AIMD.1)
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Magic Health Inc. (d.b.a. Nolla Health)
Primary Health Care for Children
Impact of a Real-time Mentoring Tool on Antibiotic Prescription (medAL-mentor)
The goal of this ancillary study, part of the DYNAMIC project, is to reduce antibiotic prescription and improve the quality of care for children in primary care in Tanzania using a near real-time mentoring tool (called…
- Trial name
- medAL-mentor (NCT05901155)
- Testing
- MedAL-mentor
- Where
- 40 sites in Tanzania
- Volunteers
- 37,000 people
- Sponsor
- Center for Primary Care and Public Health (Unisante), University of Lausanne, Switzerland
Clinical Decision Support
Optimizing the Influenza Clinical Decision Support Tool
The proposed study aims to examine several iterations of the Influenza Best Practice Alert at NYU Langone Health. The goal is to increase ordering of the influenza vaccine through the alert.
- Trial name
- NCT03415425
- Testing
- Current Version of the Influenza Alert, Alternate Modifications of the Influenza Alert
- Where
- United States
- Volunteers
- 25,881 people
- Sponsor
- NYU Langone Health
Type 1 Diabetes (T1D)
Development and Preclinical Validation of DiaBuddy, a Point-of-Care Decision Support Tool for Children With Type 1 Diabetes: A Pilot Clinical Study
Type 1 Diabetes Mellitus (T1DM) in children requires precise insulin dose adjustments and reliable sick-day decision-making on a daily basis.
- Trial name
- DiaBuddy (NCT07470905)
- Testing
- Access to DiaBuddy tool
- Where
- India
- Volunteers
- 25 people
- Sponsor
- Regency Hospital Kanpur
Hyperglycemia, Critically Ill Patients
Clinical Risk Assesment of CS-1 Decision Support System
This is a single-center, open, non-controlled clinical investigation in 10 patients at the Medical University Graz including a treatment visit (V1)and a follow up visit(V2).
- Trial name
- NCT00502645
- Testing
- CS-1 DECISION SUPPORT SYSTEM
- Where
- Austria
- Volunteers
- 10 people
- Sponsor
- Medical University of Graz
Medication Abuse, Harm Reduction
Clinical Decision Support to Increase Use of Medications for Opioid Use Disorder
The objective of this study is to evaluate the impact of clinical decision support (CDS) in the form of an alert to identify patients who may be at risk of opioid use disorder (OUD) and a clinical care pathway helping providers…
- Conditions
- Medication Abuse, Harm Reduction, Opioid Use Disorder, Supportive Care
- Trial name
- NCT06526286
- Testing
- Medications for Opioid Use Disorder Pathway Clinical Decision Support (CDS)
- Where
- United States
- Volunteers
- 200,000 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
COPD
Evaluating the EAPOC-COPD System
This study evaluates the implementation and impact of the Evidence-at-the-Point-of-Care Chronic Obstructive Pulmonary Disease (EAPOC-COPD) system, a computerized clinical decision support system designed to improve the quality of…
- Trial name
- EAPOC-COPD (NCT06852339)
- Testing
- EAPOC-COPD
- Where
- Canada
- Volunteers
- 25 people
- Sponsor
- Women's College Hospital
Critical Illness, Sepsis
Implementation of a Web Based Real Time Clinical Decision Support Tool.
In the developed world critical illness is routinely treated in an intensive care unit (ICU) by highly specialized physicians, nurses and support staff.
- Conditions
- Critical Illness, Sepsis, Respiratory Failure, Shock
- Trial name
- CERTAINp (NCT02398981)
- Testing
- Clinical decision support tool
- Where
- 10 sites in China, Croatia and 4 more
- Volunteers
- 962 people
- Sponsor
- Mayo Clinic
Hypotension
Clinical Validation of Vital-PICASO for Predicting Hypotension Within 24 Hours in General Ward Inpatients
This retrospective study evaluated the clinical performance of Vital-PICASO, an artificial intelligence-based biological signal analysis software designed to predict the risk of hypotension within 24 hours using vital-sign data…
- Trial name
- NCT07742930
- Where
- South Korea
- Volunteers
- 648 people
- Sponsor
- Huinno AIM
Referral and Consultation, Glomerulonephritis
Optimizing Referral Pathways for Patients With Hematuria and Moderate-Severe Proteinuria
The purpose of the study is to evaluate prospectively the impact of an electronic health record (EHR) alert on primary care providers' (PCP) referral to Nephrology of Geisinger patients with high risk signs (blood and protein in…
- Conditions
- Referral and Consultation, Glomerulonephritis, Hematuria, Proteinuria
- Trial name
- NCT07431931
- Testing
- Electronic Health Record alert
- Where
- United States
- Volunteers
- 1,200 people
- Sponsor
- Geisinger Clinic
Diabetic Retinopathy
Clinical Decision Support Algorithm to Predict Diabetic Retinopathy
Diabetic retinopathy (DR), a complication of diabetes, is a leading cause of blindness among working-aged adults globally. In its early stages, DR is symptomless, and can only be detected by an annual eye exam.
- Trial name
- NCT03769948
- Testing
- risk factors for diabetic retinopathy
- Volunteers
- 500 people
- Sponsor
- Oklahoma State University Center for Health Sciences
Acute Myocardial Infarction, Large Language Models
Acute Myocardial Infarction Clinical Intelligent Decision Support System
Acute Myocardial Infarction (AMI) remains the leading cause of cardiovascular mortality globally. In China, while the incidence of AMI is escalating at an annual rate of 5.2%, significant clinical challenges persist: diagnostic…
- Conditions
- Acute Myocardial Infarction, Large Language Models, Clinical Decision Support System
- Trial name
- AMI-CIDSS (NCT07367399)
- Where
- China
- Volunteers
- 15,000 people
- Sponsor
- Beijing Anzhen Hospital
Telemedicine, Pediatrics
Improving Nighttime Access to Care and Treatment; Part 4-Haiti
Children in resource-limited settings who develop illness at night are often isolated from care, resulting in progression to an emergency.
- Trial name
- INACT4-H (NCT05480930)
- Testing
- paper-based clinical decision support (dCDS) tool, digital clinical decision support (dCDS) tool
- Where
- Haiti
- Volunteers
- 7,124 people
- Sponsor
- University of Florida
Pelvic Organ Prolapse
Testing a Decision Aid for Women With Urogenital Prolapse
Development of a decision aid for women with urogenital prolapse followed by an intervention with use of the decision aid to investigate the effect on the perceived shared decision making in the clinical consultations.
- Trial name
- NCT03706716
- Testing
- decision aid developed for pelvic organ prolapse
- Where
- 3 sites in Denmark
- Volunteers
- 82 people
- Sponsor
- University of Southern Denmark