Clinical trials: Climacteric Syndrome
Turner Syndrome, Infertility, Female
Turner Syndrome Minipuberty Study
Rationale: Due to accelerated germ cell loss, infertility is a major problem in girls with Turner syndrome (TS). Therefore, cryopreservation of ovarian tissue or oocytes before exhaustion of the ovarian reserve may preserve…
- Conditions
- Turner Syndrome, Infertility, Female, Premature Ovarian Failure, Gonadal Dysgenesis
- Trial name
- Minipuberty (NCT04189406)
- Testing
- Venapunction
- Where
- 13 sites in Denmark, Germany and 3 more
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Radboud University Medical Center
Menopausal Syndrome, Menopausal Depression
4-week Seaweed Supplementation on Menopause Symptoms and Psychological Wellbeing
Menopausal symptoms have a substantial effect on quality of life as well as potentially serving as markers for future health. Previous research has suggested that diet can impact menopausal symptoms.
- Trial name
- NCT05759936
- Testing
- 500mg seaweed
- Where
- United Kingdom
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Northumbria University
Genitourinary Syndrome of Menopause
Radiofrequency Non-ablative in the Treatment of Genitourinary Syndrome of Menopause
The study is conducted in women at the menopause with a clinical diagnosis of Genitourinary Syndrome, which presents symptoms in of vulvovaginal atrophy and tract urinary and were treated with radiofrequency non ablative…
- Trial name
- NCT03506594
- Testing
- Radiofrequency non ablative
- Where
- Brazil
- Volunteers
- 58 people
- Sponsor
- Centro de Atenção ao Assoalho Pélvico
Genitourinary Syndrome of Menopause, Pelvic Floor Dysfunction
Efficacy and Safety of the Neodymium Laser in Treatment of Urogenital Tract Diseases in Women
Study objective: To evaluate the efficacy and safety of the Magic Max neodymium laser in the medical treatment of women with symptoms of genitourinary syndrome of menopausal, vulvar lichen sclerosus and pelvic floor muscle…
- Conditions
- Genitourinary Syndrome of Menopause, Pelvic Floor Dysfunction, Vulvar Lichen Sclerosus
- Trial name
- NCT05251220
- Where
- Russia
- Volunteers
- 60 people
- Sponsor
- 1st Federal Budgetary Healthcare Institution Volga District Medical Center
Metabolic Syndrome, Postmenopausal Disorder
Inofolic NRT and the Metabolic Syndrome
A prospective, randomized, controlled, open-label study will be carried out on 80 post-menopausal women affected by the metabolic syndrome (criteria are described in NIH ATP III).
- Trial name
- NCT01400724
- Testing
- Inofolic NRT
- Where
- Italy
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of Messina
Menopause, Premature, Menopause Related Conditions
Autologous PRP Infusion May Restore Ovarian Function and May Promote Folliculogenesis in POI Patients
Autologous PRP intra ovarian infusion may restore ovarian function, may promote folliculogenesis and may improve patients' hormonal profile in patients presenting with POI.
- Conditions
- Menopause, Premature, Menopause Related Conditions, Menopausal Syndrome, Premature Ovarian Failure
- Trial name
- PRP (NCT04031456)
- Testing
- Autologous Platelet Rich Plasma
- Where
- Greece
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Genesis Athens Clinic
Turner Syndrome, Ovarian Failure, Premature
Dry Eye in Women With Turner Syndrome and Women With Premature Ovarian Failure
Premature ovarian failure (POF) is known to be associated with an increased risk of ocular surface disease (dry eye), likely due to the reduction of both estrogens and androgens seen in this condition.
- Conditions
- Turner Syndrome, Ovarian Failure, Premature, Sex Chromosome Aberrations, Menopause
- Trial name
- NCT00471731
- Where
- United States
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- National Eye Institute (NEI)
Menopause
Multicentre Clinical Trial. Project EXIMe
Objective: to evaluate the effectiveness of an individualized intervention in sexual health conducted in the midwife consultation to improve the quality of life in women with Genitourinary Syndrome of Menopause.
- Trial name
- EXIMe (NCT03558451)
- Testing
- Complex intervention in sexual health, Usual care
- Where
- Spain
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Gerencia de Atención Primaria, Madrid
Genitourinary Syndrome of Menopause
The Outcome of Chinese Women With Genitourinary Syndrome of Menopause Treated With Vaginal Dehydroepiandrosterone
Genitourinary syndrome of menopause (GSM) is a common condition with prevalence was up to 80%. Symptoms associated with GSM include vaginal or vulvar dryness, itchiness, dyspareunia, increased urinary frequency or urgency and…
- Trial name
- NCT05434351
- Testing
- vaginal dehydroepiandrosterone
- Where
- Hong Kong
- Volunteers
- 4 people
- Sponsor
- Chinese University of Hong Kong
Polycystic Ovarian Syndrome, Infertility
Menopur® Versus Follistim® in Polycystic Ovarian Syndrome (PCOS)
This multicenter, randomized, open-label exploratory study will be performed in approximately 200 polycystic ovary syndrome (PCOS) but otherwise healthy females undergoing in vitro fertilization (IVF).
- Trial name
- NCT00805935
- Testing
- Menotropin, Progesterone vaginal insert, Follitropin beta
- Where
- 6 sites in United States
- Volunteers
- 110 people
- Sponsor
- Ferring Pharmaceuticals
Genitourinary Syndrome of Menopause (GSM), Breast Cancer
Determining the Extent of the Genitourinary Syndrome of Menopause Burden in Breast Cancer Survivors
Breast cancer survivors (BCS) often face unique challenges during and after treatment, including the onset of menopause-related symptoms.
- Conditions
- Genitourinary Syndrome of Menopause (GSM), Breast Cancer, Vulvovaginal Atrophy, Genitourinary Syndrome of Menopause
- Trial name
- V-light cohort (NCT07563621)
- Testing
- Questionnaires (NRS, DASS-21, EORTC QLQ-C30, EORTC QLQ-BR42, FSFI, FSDS-R)
- Where
- Belgium
- Volunteers
- 264 people, healthy volunteers welcome
- Sponsor
- Jessa Hospital
Postmenopausal Disorder
Anthropometric, Metabolic, Cardiovascular and Symptomatic Profile in Postmenopausal Women
The purpose of this study is to investigate anthropometric, metabolic, cardiovascular and symptomatic profiles in postmenopausal women.
- Trial name
- NCT01745042
- Testing
- Clinical exams
- Where
- Brazil
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Vaginal Atrophy, Dyspareunia
Elastographic Improvement of Vaginal Atrophy Treated by Erbium Yag Laser
This study is a randomized controlled sham applied study. Its aim is to evaluate the efficacy of Er:YAG laser for the treatment of atrophic vaginitis in postmenopausal women.
- Conditions
- Vaginal Atrophy, Dyspareunia, Laser, Genitourinary Syndrome of Menopause (GSM)
- Trial name
- NCT06000202
- Testing
- Fotona Dynamis Er:YAG Laser System
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 20 people
- Sponsor
- Istanbul University - Cerrahpasa
Menopausal Syndrome
Nanoparticulate Versus Micronized Steroids Delivery for Transdermal Hormone Replacement Therapy
The study aims to asses the effects of micronized (MIC) and nanoparticulate (NANO) transdermal hormone therapy (THT) on blood pressure, ultra-sensitive C-reactive protein (CRP), and cardiovascular risk factors in postmenopausal…
- Trial name
- Nanoparticle (NCT02467673)
- Testing
- Micronized estradiol + progesterone, Nanoparticulate estradiol + progesterone
- Where
- 3 sites in Brazil
- Volunteers
- 185 people, healthy volunteers welcome
- Sponsor
- University Potiguar
Climacteric Syndrome, Postmenopausal Symptoms
Multimodal Program for Climacteric Women
Your study seems to aim at emphasizing the significance of non-pharmacological and non-hormonal approaches in managing menopausal symptoms, particularly focusing on muscle training and education.
- Conditions
- Climacteric Syndrome, Postmenopausal Symptoms, Menopause, Perimenopausal Disorder
- Trial name
- NCT06419972
- Testing
- multimodal physiotherapy programme
- Where
- 2 sites in Spain
- Volunteers
- 115 people, healthy volunteers welcome
- Sponsor
- University of Valencia
Restless Legs Syndrome
Effect of Progressive Muscle Relaxation Exercises in Menopausal Women Experiencing RLS.
Restless legs syndrome is a symptom that can be seen in all stages of a woman's life, but its frequency and severity increases with menopause.
- Trial name
- NCT06156007
- Testing
- progressive muscle relaxation exercises
- Where
- Turkey (Türkiye)
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- Gazi University
Obesity
Females, Aging, Metabolism, and Exercise
This study is designed to determine whether a reduction in hormones (such as occurs during menopause) causes a decrease in calories burned during physical activity.
- Trial name
- FAME (NCT01712230)
- Testing
- GnRH agonist, Supervised cardiovascular exercise
- Where
- United States
- Volunteers
- 47 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Genitourinary Syndrome of Menopause
Natural Topical Treatment for Vulvar and Vaginal Atrophy
Genitourinary syndrome of menopause (GSM) is a chronic and progressive syndrome characterized by a collection of genital and urinary signs and symptoms secondary to the state of hypoestrogenism related to menopause.
- Trial name
- NCT05871255
- Testing
- Zantogin® Gel
- Where
- Italy
- Volunteers
- 50 people
- Sponsor
- Dr. Amjad Khan
Dry Eye Syndromes
Difference of Tear Ferning Between Women with and Without Menopausal.
Application of tear ferning test for clinical dry eye diagnosis and menopause
- Trial name
- NCT06848829
- Testing
- Pre-manepausal women
- Where
- Taiwan
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Chung Shan Medical University
Menopause, Menopausal Syndrome
Predictors of Religious Orientation Attitudes in Menopausal Women
This descriptive, cross-sectional study examines whether the severity of menopausal symptoms and attitudes toward sexual myths predict intrinsic religious orientation in menopausal women.
- Conditions
- Menopause, Menopausal Syndrome, Sexual Dysfunction
- Trial name
- MENO-RO (NCT07797296)
- Where
- Turkey (Türkiye)
- Volunteers
- 97 people, healthy volunteers welcome
- Sponsor
- KTO Karatay University