Clinical trials: Classification
Heart Valvular Disease
Multi-center Research Clinical Trial Protocol for Etiology-pathology and Repair Classification of Mitral and Tricuspid Valves
The choice of valve repair is very important in the treatment of cardiac valve disease, and its core is the etiology pathology analysis, which directly determines the design of repair strategy and the quality of postoperative…
- Trial name
- NCT07863531
- Testing
- Valve repair, Valve replacement
- Volunteers
- 200 people
- Sponsor
- Keli Huang
Diverticular Diseases
Effect of Nutritional Counseling and Mediterranean Diet on Patients With Diverticular Disease
Diverticular Disease (DD) is a frequent condition in Western populations and may be associated with complications including bleeding, perforation, acute diverticulitis, and colon strictures.
- Trial name
- Nutri-DICA (NCT06797739)
- Testing
- Nutritional counselling, Diet
- Where
- Italy
- Volunteers
- 80 people
- Sponsor
- Regione del Veneto - AULSS n. 7 Pedemontana
Biomarkers
Chilean Gastric Cancer Task Force (FORCE 1)
Background. Gastric cancer (GC) is the world's second leading cause of neoplastic mortality. Genetic alterations, response to treatments and mortality rates are highly heterogeneous across different regions.
- Trial name
- FORCE-1 (NCT03158571)
- Where
- Chile
- Volunteers
- 116 people
- Sponsor
- Pontificia Universidad Catolica de Chile
Untreated Adult Acute Lymphoblastic Leukemia, Untreated Childhood Acute Lymphoblastic Leukemia
Risk-Group Classification of Patients With Newly Diagnosed Acute Lymphoblastic Leukemia
This clinical trial is studying risk-group classification of patients with newly diagnosed acute lymphoblastic leukemia. Developing a risk-group classification guide may help doctors assign patients with newly diagnosed acute…
- Trial name
- NCT00482352
- Testing
- laboratory biomarker analysis
- Where
- 200 sites in United States, Australia and 4 more
- Volunteers
- 11,196 people
- Sponsor
- Children's Oncology Group
COVID, Sars-CoV2
Efficacy of N-Acetylcysteine (NAC) in Preventing COVID-19 From Progressing to Severe Disease
The purpose of this study is to assess the efficacy of N-acetylcysteine (NAC) in preventing those with mild or moderate COVID-19 from progressing to severe disease
- Conditions
- COVID, Sars-CoV2, SARS-Associated Coronavirus as Cause of Disease Classified Elsewhere, Oxidative Stress
- Trial name
- NCT04419025
- Testing
- N-acetylcysteine
- Where
- 4 sites in United States
- Volunteers
- 165 people, healthy volunteers welcome
- Sponsor
- Cambridge Health Alliance
Coronavirus, Coronavirus Sars-Associated as Cause of Disease Classified Elsewhere
COVID-19 Risk Stratification
The investigators seek to derive and validate a clinically useful risk score for patients with Coronavirus Disease 2019 to aide clinicians in the safe discharge of patients.
- Trial name
- NCT04339387
- Where
- United States
- Volunteers
- 1,326 people
- Sponsor
- Brigham and Women's Hospital
Undetermined Ovarian Mass
Characterization of Ovarian Masses Unable to Classify With Gynecological Ultrasonography: Value of Pelvic MRI With Perfusion- and Diffusion-weighted Imaging
The aim of the study is to prospectively evaluate the value of pelvic MRI including diffusion- and perfusion-weighted sequences in the selected group of patients that have an undetermined ovarian mass at ultrasound.
- Trial name
- IOTAMRI (NCT02425540)
- Testing
- Pelvic MRI
- Where
- Belgium
- Volunteers
- 74 people
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Classic Hodgkin Lymphoma, Lugano Classification Stage III Hodgkin Lymphoma AJCC v8
Combination Chemotherapy With or Without Rituximab in Treating Participants With Stage III-IV Classic Hodgkin Lymphoma
This phase II trial studies how well combination chemotherapy with or without rituximab works in treating participants with stage III-IV classic Hodgkin lymphoma.
- Conditions
- Classic Hodgkin Lymphoma, Lugano Classification Stage III Hodgkin Lymphoma AJCC v8, Lugano Classification Stage IV Hodgkin Lymphoma AJCC v8
- Trial name
- NCT00654732
- Testing
- Bleomycin, Dacarbazine, Doxorubicin Hydrochloride
- Where
- 4 sites in United States
- Volunteers
- 58 people
- Sponsor
- M.D. Anderson Cancer Center
COVID-19, Coronavirus Infections
Audio Data Collection for Identification and Classification of Coughing
An open access study that will define and collect digital measures of coughing in multiple populations and public spaces using various means of audio data collection.
- Conditions
- COVID-19, Coronavirus Infections, Hay Fever, Asthma
- Trial name
- NCT04326309
- Where
- United States
- Volunteers
- 336 people, healthy volunteers welcome
- Sponsor
- HealthMode Inc.
Stomach Neoplasms, Atrophic Gastritis
OLGA and OLGIM Stage System for Gastric Cancer
To validate OLGA and OLGIM staging system with serum pepsinogen for estimating GC risk according to Lauren's histologic classification in South Korea.
- Conditions
- Stomach Neoplasms, Atrophic Gastritis, Intestinal Metaplasia
- Trial name
- NCT03380052
- Where
- South Korea
- Volunteers
- 2,900 people, healthy volunteers welcome
- Sponsor
- Seoul National University Bundang Hospital
Periodontal Diseases, Periodontitis
Staging and Grading of Periodontitis: Five Years Later
The goal of this observational study is to investigate the ability of Periodontists, Clinicians with Expertise in Periodontics and General Dental Practitioners to diagnose periodontitis using the 2017 AAP / EFP World Workshop…
- Trial name
- NCT06188884
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- University of Roma La Sapienza
Medulloblastoma, Childhood
Establishment and Clinical Application of Risk Classification Model Based on Molecular Typing of Medulloblastoma in Children
The purpose of this study:(1) Development of a new risk classification model for childhood medulloblastoma. (2) Evaluation and improvement of existing individualized treatment protocols.
- Trial name
- NCT05406947
- Testing
- Prospective observational study, no intervention
- Volunteers
- 350 people
- Sponsor
- Beijing Tiantan Hospital
Atrophic Gastritis, Artificial Intelligence
AI-assisted White Light Endoscopy to Identify the Kimura-Takemoto Classification of Atrophic Gastritis
Grading endoscopic atrophy according to the Kimura-Takemoto classification can assess the risk of gastric neoplasia development.
- Conditions
- Atrophic Gastritis, Artificial Intelligence, Endoscopy
- Trial name
- NCT05916014
- Testing
- Diagnostic Test: The diagnosis of Artificial Intelligence and endosopists
- Where
- China
- Volunteers
- 1,500 people
- Sponsor
- Shandong University
Asthma (Diagnosis), Adult
Efficacy of Indonesian Asthmatic Gymnastic as Combine Pulmonary Rehabilitation Based on Asthma Classification
This study aims to evaluate the efficacy of Indonesian Asthma Gymnastic for stable asthmatic patients in all asthma classification.
- Trial name
- NCT07480616
- Testing
- Indonesian Asthma Gymnastic exercise
- Where
- Indonesia
- Volunteers
- 35 people
- Sponsor
- RSUP Persahabatan
Breast Cancer
AI Model for Classifying Breast Cancer From Histopathology Images
Breast cancer, a prevalent and potentially fatal disease, underscores the need for early and accurate detection to improve patient outcomes.
- Trial name
- NCT06717984
- Testing
- Biopsy, Mastectomy, Histopathology
- Where
- Bangladesh
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Taufiq Hasan, PhD
Bronchopulmonary Dysplasia
Multidimensional Phenotype Classification in Grade 3 Bronchopulmonary Dysplasia
Bronchopulmonary Dysplasia (BPD), or chronic lung disease of prematurity, is the most consequential complication of preterm birth and is strong predictor of childhood pulmonary and neurodevelopmental disability, particularly in…
- Trial name
- NCT06475976
- Testing
- Chest computed tomography (CT) with angiography, Bronchoscopy with bronchoalveolar lavage, Echocardiography
- Where
- United States
- Volunteers
- 130 people
- Sponsor
- Children's Hospital of Philadelphia
Suicide Ideation, Suicidal Intention
Classification and Assessment of Mental Health Performance Using Schematics
This is an open enrollment study to collect data for the optimization of smartphone-based algorithms for the early detection of mental health and suicidal risk in a student population.
- Conditions
- Suicide Ideation, Suicidal Intention, Suicide and Depression
- Trial name
- CAMPUS (NCT04275908)
- Testing
- MHSAFE app
- Where
- United States
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Clarigent Health
Myelodysplastic Syndromes
Validation of a Predictive Model of Response to Romiplostim in Patients With IPSS Low or Intermediate-1 Risk MDS and Thrombocytopenia
There are currently no licensed drugs in the EU to treat thrombocytopenia in MDS patients classified as IPSS low/int-1. Prior studies with romiplostim (a TPO receptor agonist) in MDS found that baseline concentration of TPO as…
- Trial name
- EUROPE (NCT02335268)
- Testing
- N-Plate / romiplostim
- Where
- 36 sites in France, Germany
- Volunteers
- 77 people
- Sponsor
- Gesellschaft fur Medizinische Innovation - Hamatologie und Onkologie mbH
Radiation Dermatitis, Head and Neck Cancer
Deep Learning-based Classification and Prediction of Radiation Dermatitis in Head and Neck Patients
to develop a deep learning-based model to grade the severity of radiation dermatitis (RD) and predict the severity of radiation dermatitis in patients with head and neck cancer undergoing radiotherapy, so as to provide support…
- Trial name
- NCT05607225
- Where
- 2 sites in China
- Volunteers
- 300 people
- Sponsor
- Cancer Institute and Hospital, Chinese Academy of Medical Sciences
Alcoholic Liver Disease
French National MICMAF Cohort
Excessive alcohol consumption is a major public health problem, particularly in France. It is the leading cause of cirrhosis and hepatocellular carcinoma.
- Trial name
- MICMAF (NCT05895890)
- Testing
- Sequential sampling (stool, saliva, serum) .
- Where
- France
- Volunteers
- 1,000 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris