Clinical trials: Class III Malocclusion
Retrognathism, Prognathism
Pharmacological Treatment on the Recovery of Neurosensory Disturbance After Bilateral Sagittal Split Osteotomy
The bilateral sagittal split osteotomy (BSSO) of the mandible is one of the most used surgical techniques to achieve a harmonious jaw relation in the context of orthognathic surgery.
- Conditions
- Retrognathism, Prognathism, Orthognathic Surgery, Neurosensory Disorder
- Trial name
- NCT05536596
- Testing
- Orthognathic Surgery, Melatonin 10 MG Oral Tablet, Hydroxycobalamin
- Volunteers
- 220 people, healthy volunteers welcome
- Sponsor
- Universitat Internacional de Catalunya
Maxillary Retrognathism, Children
Treatment of Mandibular Overjet in Children With Maxillary Retrognathism
The project involves a 10-year prospective longitudinal cohort multicentre study where orthodontic treatment and treatment effect is followed in children with Cl III due to maxillary retrognathia who undergo standardized…
- Conditions
- Maxillary Retrognathism, Children, Treatment, Class III Malocclusion
- Trial name
- NCT07706400
- Testing
- Interceptive treatment
- Where
- 3 sites in Denmark, Sweden
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Malmö University
Skeletal Malocclusion, Class III Malocclusion
The Effect of Splint Usage in Laterognathic Cl III Orthognathic Surgery Patients
It is crucial to maintain the anatomic condylar positions during orthognathic surgery. Condylar positions are affected directly under general anesthesia because of joint and muscle relaxation.
- Conditions
- Skeletal Malocclusion, Class III Malocclusion, Laterognathia
- Trial name
- TMJ (NCT05216874)
- Testing
- Oclusal Splint
- Where
- Turkey (Türkiye)
- Volunteers
- 48 people
- Sponsor
- Bezmialem Vakif University
Class III Malocclusion
Patient Specific Intraoral Inverted-L Osteotomy Modified With Inferior Alveolar Nerve Relocation in Corrective Mandibular Surgery
Bilateral sagittal split osteotomy (BSSO) is considered the main osteotomy design in corrective mandibular surgery, however abnormal anatomical configuration of the posterior mandible with rolled out inferior border and thin…
- Trial name
- NCT05397002
- Testing
- patient specific inverted L mandibular osteotomy modified with inferior alveolar nerve relocation
- Where
- Egypt
- Volunteers
- 20 people
- Sponsor
- Cairo University
Skeletal Class II Malocclusion, Skeletal Class III Malocclusion
Clinical and Radiographic Evaluation of Low Sagittal Medial Ramus Osteotomy for Treatment of Skeletal Class II and Class III Malocclusion
This prospective clinical trial aims to evaluate the clinical and radiographic outcomes of the low sagittal medial ramus osteotomy-a technical modification of the conventional sagittal split osteotomy (SSO)-for treating patients…
- Conditions
- Skeletal Class II Malocclusion, Skeletal Class III Malocclusion, Dentofacial Deformities
- Trial name
- NCT07746700
- Testing
- Low Sagittal Medial Ramus Osteotomy
- Volunteers
- 11 people
- Sponsor
- Al-Azhar University
Effect of PowerScope Appliance in Treatment of Patients With Class 3 Malocclusion
Effect of Skeletally Anchored Reversed PowerScope Appliance in Orthodontic Treatment of Patients With Class III Malocclusion
the PowerScope appliance is found to be efficient for the treatment of class II malocclusion. Accordingly, it appears valuable to investigate the efficiency of skeletally anchored powerScope in the treatment of class III…
- Trial name
- NCT05475548
- Testing
- powerscope
- Where
- Egypt
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Al-Azhar University
Abnormalities, Jaw, Malocclusion, Angle Class III
First-In-Man Performance and Safety Evaluation of the CARLO® Device in Midface Osteotomies
The study product is a Cold Ablation Robot-guided Laser Osteotome (CARLO®) robotic surgery device. It is a device that removes hard tissue such as bone by means laser ablation - it is therefore an alternative to Piezo-Electric…
- Trial name
- NCT03901209
- Testing
- Mid-face osteotomy
- Where
- 4 sites in Austria, Germany and 1 more
- Volunteers
- 31 people
- Sponsor
- Advanced Osteotomy Tools (AOT) AG
Skeletal Class III Malocclusion
Comparison of Maxillary Protraction Using Tooth-borne Facemask Versus Skeletal Anchorage Chin-plate in Class III Growing Patients
This retrospective non-randomized controlled clinical trial aimed to compare the skeletal and dentoalveolar effects of two orthopedic treatment protocols for skeletal Class III malocclusion in growing patients: a conventional…
- Trial name
- NCT07383259
- Testing
- Tooth-Borne Expander with Facemask (FM), Hybrid Skeletal Anchorage Expander with Chin-Plate (SA)
- Volunteers
- 36 people
- Sponsor
- Universidad Complutense de Madrid
Maxillary Prognathism, Maxillary Retrusion
Custom Made Plate in Orthognathic Surgery
Orthognathic surgery has traditionally been used to correct dentofacial deformities. Conventional methods rely on 2D radiographic images, occlusal splints, and dental casts, but these approaches have limitations, such as errors…
- Trial name
- OGS (NCT06772688)
- Testing
- orthognathic surgery
- Where
- Egypt
- Volunteers
- 8 people
- Sponsor
- Faculty of Dental Medicine for Girls
Class III Malocclusion, Root Resorption
Determining the Presence of RAP in Orthognathic Patients and Its Effect on Root Resorption by Biomarkers
A prospective clinical trial to what extent inflammatory biomarkers are affected by the medication after orthognathic surgery in early surgical cases and whether these biomarkers affects the amount of maxillary or mandibular…
- Trial name
- RAP (NCT04823325)
- Testing
- Orthognathic Surgery
- Where
- Turkey (Türkiye)
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- Bezmialem Vakif University
Skeletal Class III Malocclusion
Comparison of Ertty Gap III and Facemask Therapy for Skeletal Class III Correction
This single-center, parallel-group randomized clinical trial compared 2 orthopedic treatment approaches in growing patients with skeletal Class III malocclusion associated predominantly with maxillary deficiency: the Ertty Gap…
- Trial name
- NCT07771660
- Testing
- Ertty Gap III Appliance, Facemask Therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 42 people
- Sponsor
- Ankara University
Skeletal Class III Malocclusion, Transverse Maxillary Deficiency
Effects of Invisalign Palatal Expander vs Rapid Palatal Expander With Facemask in Growing Class III Patients
The goal of this clinical trial is to compare two types of palatal expanders used with a facemask in children who have skeletal Class III and a narrow upper jaw.
- Trial name
- NCT07485478
- Testing
- Invisalign Palatal Expander (IPE), Rapid Palatal Expander (RPE)
- Where
- Thailand
- Volunteers
- 24 people
- Sponsor
- Mahidol University
Anterior Crossbite, Class III Malocclusion in Growing Patients
Comparison Between Protraction Facemask and Upper Braces for Underbite Correction in Growing Children
The goal of this clinical trial is to compare the effectiveness of a protraction facemask and upper partial fixed appliance in correcting anterior crossbite in growing children with class III malocclusion.
- Trial name
- NCT06759896
- Testing
- Protraction facemask, Upper partial fixed appliance
- Where
- Malaysia
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- University of Malaya
Class III Malocclusion
Palatal Versus Buccal Protraction Using Plates Assisted With Facemask in Growing Class III Patients
to compare Palatal and buccal protraction using plates assisted with facemask in growing class III patients
- Trial name
- NCT06452368
- Testing
- facemask
- Where
- Egypt
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Mansoura University
Malocclusion, Angle Class I, Malocclusion, Angle Class II
AI-Assisted Versus Conventional Orthodontic Diagnosis and Treatment Planning
This study compared an artificial intelligence-assisted orthodontic diagnostic workflow using WebCeph with a conventional clinician-based workflow.
- Conditions
- Malocclusion, Angle Class I, Malocclusion, Angle Class II, Malocclusion, Angle Class III
- Trial name
- AI-OrthoDx (NCT07690774)
- Where
- Yemen
- Volunteers
- 120 people
- Sponsor
- Ben Hafeed Dental Center
Malocclusion, Angle Class III
Periodontal Ligament Stress Level and Tooth Movement
Orthodontic treatment requires application of force systems to individual teeth or groups of teeth, which results in a cellular response with periodontal ligament (PDL) and alveolar bone remodeling.
- Trial name
- NCT00099814
- Testing
- Two different loop designs which deliver distinctive forces
- Where
- Canada
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Alberta
Class III Malocclusion, Cross Bite
Evaluation of Pain, Discomfort and Acceptance During the Orthodontic Treatment of Class III Malocclusion
The aim of this study is to evaluate the levels of pain, discomfort and acceptance between two treatment modalities of Class III correction of growing patients in the late mixed dentition period.
- Conditions
- Class III Malocclusion, Cross Bite, Orthodontic Appliance Complication
- Trial name
- NCT03976635
- Testing
- Removable Mandibular Retractor, Bone-anchored intermaxillary traction
- Where
- Syria
- Volunteers
- 38 people
- Sponsor
- Damascus University
Class III Malocclusion, Dentofacial Anomalies, Including Malocclusion
Intraoral Device vs Facial Mask for Class III Treatment
The aim of this randomized controlled trail is to compare the efficacy of an intraoral device (the Carriere® Motion 3D™ Class III Appliance) with the facial mask for the early treatemnt of Class III malocclusion.
- Trial name
- NCT04387175
- Testing
- Carriere Motion 3D Class III Appliance, Facial mask
- Volunteers
- 32 people
- Sponsor
- Azienda Ospedaliero-Universitaria Careggi
Cleft Lip and Palate
Clinical Effectiveness of Late Maxillary Protraction for Cleft Lip and Palate
Patients with cleft lip and palate frequently develop Class III (Cl III) malocclusions or underbites following early cleft repair surgeries.
- Trial name
- PROTRACTSURG (NCT02789787)
- Testing
- Maxillary Protraction, Orthognathic Surgery
- Where
- 2 sites in United States
- Volunteers
- 117 people, healthy volunteers welcome
- Sponsor
- University of Southern California
Skeletal Class III Malocclusion
Management of Skeletal Class III Malocclusion With Digital Bonded Reverse Twin Block in Mixed Dentition
The purpose of this study is to evaluate dentoalveolar \& skeletal effects of digital bonded reverse twin block in treatment of skeletal class III malocclusion in mixed dentition.
- Trial name
- NCT07376954
- Testing
- Digital Bonded Reverse Twin Block
- Where
- Egypt
- Volunteers
- 21 people
- Sponsor
- Mansoura University