Clinical trials: Circadian Rhythm
Shift-work Disorder
EMS Providers' Health Initiative Study
This study aims to explore dietary factors that influence glycemic control in night shift EMS providers and to test the feasibility of a dietary intervention among these providers.
- Trial name
- NCT05153759
- Testing
- Meal service
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- State University of New York at Buffalo
Sleep Deprivation, Circadian Dysregulation
Cardiometabolic Risk of Shiftwork
The overall goal of the present application is to test the hypothesis that shift workers, who are chronically exposed to circadian misalignment and sleep loss, have a higher cardio-metabolic risk than day workers, and that the…
- Conditions
- Sleep Deprivation, Circadian Dysregulation, Shift-Work Sleep Disorder
- Trial name
- SW (NCT01264913)
- Testing
- sleep extension & circadian alignment
- Where
- United States
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- University of Chicago
Healthcare Workers, Stress Level
Effects of VR-based Respiratory Training on Motor Reaction Time and Correctness, Stress Levels, Attention, Motor Skills, Postural Stability and Sleep Quality in Shift Healthcare Workers
This study investigates the effects of virtual reality (VR)-based respiratory training on various physiological and cognitive functions in shift-working healthcare professionals, including paramedics and nurses.
- Conditions
- Healthcare Workers, Stress Level, Emergency Department, Shift Work Sleep Disorder
- Trial name
- NCT06926257
- Testing
- Experimental group (B) - breathing training using VR, Experimental group (C) - breathing training using relaxation music
- Where
- Poland
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Poznan University of Physical Education
Dementia, Alzheimer Disease
Multidisciplinary Expert System for the Assessment & Management of Complex Brain Disorders
The Multidisciplinary Expert System for the Assessment \& Management of Complex Brain Disorders (MES-CoBraD) is an interdisciplinary project combining Real-World Data (RWD) from multiple clinical and consumer sources through…
- Conditions
- Dementia, Alzheimer Disease, Epilepsy, Sleep Disorder
- Trial name
- MES-CoBraD (NCT05171725)
- Testing
- EEG,PSG, biosample collection (blood and CSF), neuropsychological testing
- Where
- 4 sites in Greece, Israel and 2 more
- Volunteers
- 635 people, healthy volunteers welcome
- Sponsor
- Neurological Institute of Athens
Insomnia, Sleep
Vestibular Nerve Stimulation to Improve Sleep
A randomized, double blind sham controlled clinical trial to evaluate the efficacy of vestibular nerve stimulation (VeNS) compared to a sham control a as a means of improving sleep as measured by ISI scores and EEG recordings The…
- Conditions
- Insomnia, Sleep, Sleep Disorders, Circadian Rhythm
- Trial name
- NCT04219566
- Testing
- VeNS
- Where
- India
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Neurovalens Ltd.
Autistic Disorder
Characterisation of Circadian Rhythm in Autistic Spectrum Disorder
Autism spectrum disorders (ASDs) are complex neurodevelopmental conditions characterized by deficits in social communication, delay in language and repetitive behaviors.
- Trial name
- NCT01984944
- Testing
- Autistic functional exploration, Control functional exploration
- Where
- France
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Circadian Rhythm, Cardiometabolic Health
Circadian Time Restricted Eating
The goal of this study is to learn more about how the time in which participants consume their meals relative to their personalized circadian rhythm influences their overall cardiometabolic health and weight.
- Conditions
- Circadian Rhythm, Cardiometabolic Health, Weight Loss, Cardiovascular Health
- Trial name
- CTRE (NCT05628012)
- Testing
- Circadian Based Time Restricted Eating
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Oregon Health and Science University
Circadian Rhythm Disorders
Human Circadian Sensitivity to Very Short Light Pulses
The mammalian eye serves both visual and non-image-forming functions. New information about the non-image-forming anatomy and physiology of the eye has revealed effects of ocular light stimuli on human circadian rhythms…
- Trial name
- NCT01330992
- Testing
- Ocular light or darkness exposure
- Where
- United States
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Brigham and Women's Hospital
Sleep, Circadian Rhythm
Morning Bright Light Therapy and Daytime Functioning in University Students
This study tests whether a week of morning bright light therapy changes how well healthy young adults sleep and how alert, positive, and mentally sharp they feel during the day.
- Conditions
- Sleep, Circadian Rhythm, Daytime Sleepiness, Mood
- Trial name
- BLIGHT (NCT07685262)
- Testing
- Bright light therapy (10,000 lux light box)
- Where
- Hong Kong
- Volunteers
- 153 people, healthy volunteers welcome
- Sponsor
- The Hong Kong Polytechnic University
Sleep Disorders
Sleep Length and Circadian Regulation in Humans
This research will examine why sleep restriction reduces the body clock's response to bright light. The results will enable the optimization of the bright light treatment of people who suffer from circadian rhythm sleep…
- Trial name
- HAM (NCT00843843)
- Testing
- Bright light box
- Where
- United States
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Rush University Medical Center
Healthy
the Effects of Different Dietary Phosphorus Intake on the Circadian Pattern of Serum Phosphate in Normal Subjects
The purpose of this study is to investigate the effects of normal diet and low-phosphate diet on the level and the circadian pattern of serum phosphate concentration in normal subjects and to explore the underlying mechanisms.
- Trial name
- NCT02636153
- Testing
- normal diet, restricted phosphate diet
- Where
- China
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- Huashan Hospital
Circadian Rhythm, Postoperative Pain
The Effect of Circadian Rhytm on Postoperative Pain Undergoing Pediatric Surgery
These circadian rhythms are self-sustained, endogenous oscillations generated by circadian clocks that persist with a period of around 24 -h under constant conditions.
- Trial name
- NCT05379192
- Testing
- Group 1, Group 2, Group 3, Group 4
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Faruk Cicekci
Chronic Insomnia, Melatonin
Effect of Suanzaoren Decoction and Huanglian Wendan Decoction on Biorhythm of Insomnia Patients
The purpose of this study was to examine the impact of Chinese medicine on melatonin levels in patients with insomnia
- Conditions
- Chronic Insomnia, Melatonin, Circadian Rhythm, Suanzaoren Decoction and Huanglian Wendan
- Trial name
- NCT06467851
- Testing
- Suanzaoren Decoction and Huanglian Wenda Decoction
- Where
- 2 sites in China
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- The First Affiliated Hospital with Nanjing Medical University
Sleep Disorder Circadian Rhythm, Delayed Sleep Phase Type
SleepHelsinki! CIRCADIAN SLEEP REGULATION IN ADOLESCENCE
Adolescence associates with alterations in sleep-wake organization, such as later circadian phase preference. Simultaneously external pressures, such as evening-driven social activities increase.
- Trial name
- SleepHel (NCT02964598)
- Testing
- Gamified intervention, Sleep coaching, Bright light
- Where
- Finland
- Volunteers
- 270 people, healthy volunteers welcome
- Sponsor
- University of Helsinki
Hypogonadism, Male
Salivary Testosterone in Men: Diurnal Variation and Post-Prandial Responses
The purpose is to evaluate Sal-T against standard biomarkers of male gonadal status based on serum T, calculated free T and BAT. The optimal salivary sampling in terms of fasting and time of day will also be defined.
- Trial name
- SalT (NCT04326673)
- Testing
- Testosterone Measurements in healthy volunteers after fasting, Testosterone Measurements after glucose loading
- Where
- United Kingdom
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- The Royal Wolverhampton Hospitals NHS Trust
Sleep Disorders, Circadian Rhythm
Circadian Phase Adjustment and Improvement of Metabolic Control in Night Shift Workers
EuRhythDia II is a multicenter, randomized, double-blind controlled study. The rationale of EuRhythdia is to explore the effects of 12 weeks of timed melatonin treatment on circadian rhythm, metabolic control and cardiovascular…
- Trial name
- NCT02108353
- Testing
- Melatonin 2mg
- Where
- 3 sites in Germany, Italy
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Universitätsklinikum Hamburg-Eppendorf
Stress Disorders, Stress
Measuring the Effectiveness of Forest Therapy to Alleviate Stress Among International Students
International students often face high levels of stress, leading to mental health conditions, from factors including cultural and social change, educational system, financial insecurity and family responsibilities.
- Conditions
- Stress Disorders, Stress, Anxiety, Anxiety Depression (Mild or Not Persistent)
- Trial name
- FTIS-2024 (NCT06792656)
- Testing
- standardized Forest Therapy session (120 min)
- Where
- Australia
- Volunteers
- 360 people, healthy volunteers welcome
- Sponsor
- International Nature and Forest Therapy Alliance
Alteration of Cognitive Function, Ageing
Health Behaviors and Time-of-Day: Older Adult Cognitive Function
This is a single-center, observational study design. Enrolled participants will be typically, healthy older adults. Participants will complete daily computerized measures, in addition to continuously wearing an Actiwatch device.
- Trial name
- OA-TIME (NCT02300272)
- Testing
- Polysomnograph, Actiwatch
- Where
- United States
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- University of Florida
Sleep
Circadian Rhythms and Homeostatic Sleep Drive and Their Effect on Reward and Cognitive Control Systems in Adolescents
Adolescence is a time of heightened reward sensitivity and greater impulsivity. On top of this, many teenagers experience chronic sleep deprivation and misalignment of their circadian rhythms due to biological shifts in their…
- Trial name
- CARRS-P1 (NCT05336084)
- Testing
- Ultradian sleep/wake protocol
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Parkinson's Disease
Circadian Rhythms and Sleep-Wake Cycles in Parkinson's Disease
Disruption of sleep and alertness is one of the most disabling non-motor symptoms of Parkinson's disease (PD). Mechanisms leading to impaired sleep and alertness in PD are not well understood, and treatment options remain…
- Trial name
- NCT01742182
- Testing
- Light exposure
- Where
- United States
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital