Clinical trials: Circadian Misalignment
Night Shift Work, Obesity & Overweight
Shift Workers' Health Behavior Action Program Across Europe
This study evaluates the effects of a Combined Lifestyle Intervention Program (CLIP) on sleep, lifestyle behaviors, obesity risk and health in night-shift workers.
- Conditions
- Night Shift Work, Obesity & Overweight, Circadian Misalignment
- Trial name
- SHAPE (NCT07631767)
- Testing
- Combined Lifestyle Intervention
- Where
- 5 sites in Germany, Netherlands and 1 more
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Wageningen University
Circadian Dysregulation
Development of Countermeasures Against Adverse Metabolic Effects of Shift Work
The goal of this application is to determine whether changing the timing of food intake prevents the adverse metabolic effects of circadian misalignment.
- Trial name
- NCT02291952
- Testing
- Meal schedule
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Brigham and Women's Hospital
Circadian Rhythm, Time Perception
Circadian Timing and Time Perception in Healthy Adults
This study examines how a person's natural daily rhythm ("chronotype") affects the way time is experienced and judged. Healthy Danish-speaking adults (23-45 years) who are clearly morning-type or evening-type will complete two…
- Trial name
- ChronoTime (NCT07292597)
- Testing
- Session timing relative to chronotype
- Where
- Denmark
- Volunteers
- 128 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
Sleep, Metabolism Changes
Nighttime Synchrony of Your Nutrition and Circadian Health
Sleep is an important factor for overall health. This study will see how different light exposure patterns and food intake impact a person's metabolism (how the body breaks down food) when sleeping is reduced.
- Conditions
- Sleep, Metabolism Changes, Circadian Rhythm, Lifestyle Factors
- Trial name
- N-Sync (NCT07329283)
- Testing
- Central Clock Misalignment, Peripheral Misalignment
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University of Utah
Shift-work Disorder
Use of Consumer Sleep Technology to Treat Shift Work Disorder
The purpose of this study is to examine the effectiveness of a personalized light exposure schedule for Shift Work Disorder (SWD) in night shift workers compared to a non-personalized light exposure schedule.
- Trial name
- SHIFT (NCT05186233)
- Testing
- Phototherapy
- Where
- United States
- Volunteers
- 63 people
- Sponsor
- Henry Ford Health System
Diabetes Mellitus, Type 2, Insulin Resistance
Circadian Misalignment and Insulin Sensitivity
This study will evaluate the effect of circadian misalignment on insulin sensitivity in healthy lean subjects in a randomized cross-over design.
- Trial name
- NCT02580513
- Testing
- Circadian Misalignment
- Where
- Netherlands
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Maastricht University Medical Center
ADHD
Impact of Short and Mistimed Sleep on Adolescents With ADHD: The Adolescent Attention and Circadian Timing Study
Many adolescents go to bed late and wake up early for school. Science is only beginning to understand how sleep schedules can affect them.
- Trial name
- AACT (NCT07684417)
- Testing
- Aligned sleep extension, Misaligned sleep extension
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Circadian Rhythm Disorders
Daytime Bright Light, Circadian Abnormalities, and Delirium in Medical ICU Patients
To determine if daytime bright light will promote circadian alignment and shorten or prevent delirium.
- Trial name
- NCT03684460
- Testing
- Daytime Bright Light, Usual Light
- Where
- United States
- Volunteers
- 68 people
- Sponsor
- Yale University
Circadian Rhythm Sleep Disorder of Shift Work Type, Metabolic Disease
Countermeasures to Circadian Misalignment
Insufficient sleep and circadian misalignment are independent risk factors for the development of obesity and diabetes, yet few strategies exist to counter metabolic impairments when these behaviors are unavoidable.
- Conditions
- Circadian Rhythm Sleep Disorder of Shift Work Type, Metabolic Disease, Insulin Sensitivity
- Trial name
- C2CM (NCT04966351)
- Testing
- Time-restricted feeding, Circadian Misalignment
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Colorado State University
Inflammatory Bowel Diseases, Crohn Disease
Circadian Misalignment in Inflammatory Bowel Disease
This study is to explore the role the sleep/wake cycle (Circadian Rhythm) has on Inflammatory Bowel Disease. Participants will be asked to attend two clinic visits 14 days apart.
- Conditions
- Inflammatory Bowel Diseases, Crohn Disease, Ulcerative Colitis
- Trial name
- NCT04637399
- Where
- United States
- Volunteers
- 52 people
- Sponsor
- Rush University Medical Center
Non-visual Effects of Light, Chronic Variable Sleep Deficiency
Sleep, Light, Circadian, Central Oxidative Stress
Irregular sleep timing and sleep deficiency are pervasive in society despite evidence that sleep deficiency impairs cognition and is linked to neurodegenerative disease.
- Trial name
- NCT07471126
- Testing
- Chronic Variable Sleep Deficiency, Sleep- and Circadian-Informed Lighting, Dim Light
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Beth Israel Deaconess Medical Center