Clinical trials: Cigarette Smoking Behavior
Cigarette Smoking
Effects of Choice Bundling on Valuation of Delayed Gains and Losses in Cigarette Smokers
The present study will investigate the effects of choice bundling, in which a single choice produces a series of repeating consequences, on valuation of delayed monetary gains and losses in an online panel of cigarette smokers.
- Trial name
- NCT05110716
- Testing
- Bundle-size 1, Bundle-size 3, Bundle-size 9
- Where
- United States
- Volunteers
- 308 people
- Sponsor
- Virginia Polytechnic Institute and State University
Drug Drug Interaction (DDI)
Drug-Drug Interaction (DDI) Study for TD-9855
This study is designed to assess the effect of fluvoxamine, itraconazole and smoking on the PK disposition of multiple doses TD-9855 in healthy male subjects.
- Trial name
- NCT03432793
- Testing
- TD-9855, Fluvoxamine, Itraconazole
- Where
- United States
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- Theravance Biopharma
Electronic Cigarette Use, Pulmonary Disease
Factors That Impact the Relationship Between Pulmonary Status and Actual Electronic Cigarette Use
Secondary data analysis will be performed as our approach to complete the study. A nationally representative dataset (BRFSS, 2017) will be used to answer the above hypotheses.
- Trial name
- NCT04135404
- Testing
- health-related telephone surveys
- Volunteers
- 400,000 people
- Sponsor
- University of Alabama at Birmingham
Cigarette Smoking
E-Cigarettes and Financial Incentives to Promote Tobacco Harm Reduction Among Adults Accessing Shelter Services
This randomized controlled trial evaluated the feasibility and potential efficacy of 1) e-cigarette switching (EC) or 2) e-cigarette switching + financial incentives for combustible cigarette cessation (EC+FI)
- Trial name
- EXCHANGE (NCT03743532)
- Testing
- E-cigarette Switching, Financial Incentives
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Oklahoma
Cigarette Smoking, Nicotine Dependence
Treatment of Smoking Among Individuals With PTSD
This study will examine the effect of combining prolonged exposure, a cognitive-behavioral treatment program for post-traumatic stress disorder (PTSD) with medication (varenicline) and counseling treatments for smoking cessation.
- Conditions
- Cigarette Smoking, Nicotine Dependence, Post-traumatic Stress Disorder, Tobacco Use Disorder
- Trial name
- NCT00937235
- Testing
- Varenicline, Medication Management Counseling, Prolonged Exposure
- Where
- United States
- Volunteers
- 142 people
- Sponsor
- University of Pennsylvania
Tobacco Products, Smoking Behavior
Communicating About Nicotine Reduction in Cigarettes
The goal of this clinical trial is to learn how a messaging campaign about reduced nicotine cigarettes and policy, combined with the use of very low nicotine cigarettes (VLNCs), affects smoking behavior and attitudes among adult…
- Conditions
- Tobacco Products, Smoking Behavior, Cigarette Use
- Trial name
- NCT06787937
- Testing
- VLNC messages, Control message
- Where
- 2 sites in United States
- Volunteers
- 1,230 people, healthy volunteers welcome
- Sponsor
- Georgia State University
Breast Cancer, Tobacco Dependence
Tobacco Dependence in Breast Cancer Patients Trial of Varenicline (Chantix)
Breast cancer patients who smoke, are at greater risk for treatment complications. The purpose of this study is to see if the researchers can find ways to help patients who have breast cancer quit smoking.
- Trial name
- NCT01532232
- Testing
- varenicline
- Where
- United States
- Volunteers
- 7 people
- Sponsor
- Memorial Sloan Kettering Cancer Center
Tobacco Use Disorder
Project Q: Cue-based Treatment Intervention to Promote Cessation Among People Who Smoke Lightly or Non-daily
This study aims to test the feasibility and acceptability of a remotely delivered cue-based treatment intervention to promote smoking cessation among people who smoke lightly or non-daily.
- Trial name
- NCT07425119
- Testing
- Cognitive Behavioral Therapy (CBT), Cue-based treatment intervention
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Duke University
Smoking
Evaluation of Biological and Functional Changes in Healthy Smokers After Switching to THS 2.2 for 26 Weeks
The aim of the study is to demonstrate clinical, biological and functional health changes in smokers switching to the candidate modified risk tobacco product: Tobacco Heating System 2.2 (THS 2.2) as compared to smokers continuing…
- Trial name
- NCT02396381
- Testing
- THS 2.2, CC
- Where
- 19 sites in United States
- Volunteers
- 1,039 people, healthy volunteers welcome
- Sponsor
- Philip Morris Products S.A.
Obstructive Sleep Apnea, Smoking
Effects of Obstructive Sleep Apnea and/or Cigarette Smoking on Endothelial Function
The hypothesis of this study is that either obstructive sleep apnea (OSA) or cigarette smoking (CS) exposure would produce oxidative stress and inflammation leading to endothelial injury, and the combined exposure would be…
- Trial name
- NCT00957463
- Where
- Hong Kong
- Volunteers
- 150 people
- Sponsor
- The University of Hong Kong
COPD
Chronic Obstructive Pulmonary Disease (COPD) Biomarker Identification Study
Chronic obstructive pulmonary disease (COPD) is a common inflammatory disease of the airway affecting approximately 10% of individuals aged 40 years or more with a smoking history.
- Trial name
- NCT01780298
- Where
- United Kingdom
- Volunteers
- 252 people, healthy volunteers welcome
- Sponsor
- Philip Morris Products S.A.
Smoking, Tobacco Smoking
Effect of Packaging on Smoking Perceptions and Behavior
The investigators are addressing two critical areas identified by the FDA: the impact of cigarette packaging and labeling on consumer perceptions and on smoking behavior; and the effectiveness of graphic warning labels on…
- Trial name
- CASA (NCT02676193)
- Testing
- Effect of Packaging on Smoking Perceptions and Behavior
- Where
- United States
- Volunteers
- 359 people
- Sponsor
- University of California, San Diego
Cigarette Smoker, Current Smoker
18F-FSPG PET/CT in Diagnosing Early Lung Cancer in Patients With Lung Nodules
This phase II trial studies how well 18F-FSPG positron emission tomography (PET)/computed tomography (CT) work in diagnosing early lung cancer in patients with indeterminate lung nodules.
- Conditions
- Cigarette Smoker, Current Smoker, Former Smoker, Multiple Pulmonary Nodules
- Trial name
- NCT03824535
- Testing
- Computed Tomography, Fludeoxyglucose F-18, Fluorine F 18 L-glutamate Derivative BAY94-9392
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Andrei Iagaru
Smoking ( Cigarette), Cornea
Acute Ocular Effects of Cigarette Smoking
This prospective study aims to evaluate the short-term effects of smoking on corneal tomographic and biometric measurements in healthy adults.
- Conditions
- Smoking ( Cigarette), Cornea, Anterior Eye Segment Measurements
- Trial name
- NCT07580040
- Testing
- Cigarette Smoking Exposure, No Smoking Exposure
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Istanbul University
Vaping
Modeling Stress-precipitated Vaping Behavior
The primary aims of this pilot study were to (1) initially validate the applicability of a human laboratory model of relapse initially developed for smokers to e-cigarette users; (2) to use this human laboratory model of lapse…
- Trial name
- NCT04522362
- Testing
- Control task and Trier Social Stress Task
- Where
- United States
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- Clemson University
Electronic Cigarette Use, Tobacco Smoking
Characterize the Nicotine Uptake and Subjective Effects With Use of JUUL Electronic Nicotine Delivery Systems
The purpose of this study is to estimate nicotine uptake and assess subjective effects during ad libitum use sessions of 4 flavors of JUUL ENDS (also referred to as nicotine salt pod system; NSPS) products (i.e., Virginia…
- Trial name
- NCT04123041
- Testing
- JUUL ENDS, Combustible cigarette, comparator e-cigarette, Nicorette gum
- Where
- 2 sites in United States
- Volunteers
- 137 people, healthy volunteers welcome
- Sponsor
- Juul Labs, Inc.
Smoking Cessation
Randomized Clinical Trial to Reduce Harm From Tobacco
Using the NIH-funded Way to Health platform, the investigators will conduct this smoking cessation RCT among Vitality/Discovery beneficiaries.
- Trial name
- NCT02328794
- Testing
- E-cigarette free access, E-cigarette/NRT/Zyban/Chantix Choice, Outcome Incentive arm
- Where
- United States
- Volunteers
- 6,006 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Cigarette Smoking Behavior
Effects of Implicit Messaging by Cigarette Pack Color on Smoking Behaviors
The purpose of this study is to examine the effect of changes in cigarette package color and warning label features on smoking behaviors and beliefs about cigarette risks.
- Trial name
- NCT02301351
- Testing
- Graphic Warning Label, Text Warning Label
- Where
- United States
- Volunteers
- 316 people
- Sponsor
- University of Pennsylvania
Tobacco Use Disorder
Impact of Cigar Flavor in Dual Users
The purpose of this study is to understand addiction to filtered cigars (FCs) compared to cigarettes in young adults, ages 21-34, who smoke both cigarettes and cigars.
- Trial name
- NCT04487470
- Testing
- Flavored filtered cigars, Unflavored filtered cigars
- Where
- United States
- Volunteers
- 89 people, healthy volunteers welcome
- Sponsor
- UConn Health
Cigarette Smoking, Marijuana Abuse
Mobile Contingency Management for Marijuana and Tobacco Cessation
The purpose of this pilot project is to pilot-test a combined cannabis and smoking cessation treatment. The intervention combines mobile technology with behavioral strategies, counseling, and medications.
- Trial name
- NCT02869451
- Testing
- bupropion, transdermal nicotine patch, Nicotine polacrilex
- Where
- United States
- Volunteers
- 7 people
- Sponsor
- Duke University