Clinical trials: Cigarette Addiction
Nicotine Dependence
Study on Sit to Quit Phone Intervention
This study is designed to test the effectiveness of the smoking cessation intervention "Sit to Quit" through a randomized-control trial.
- Trial name
- NCT02840435
- Testing
- Sit to Quit, Quit for Life
- Where
- United States
- Volunteers
- 23 people
- Sponsor
- Duke University
Tobacco Dependence, Smoking Cessation
Using Non-invasive Brain Stimulation (tDCS) With Varenicline for Treating Tobacco Dependence
The addition of tDCS as an adjunct to pharmacotherapy is a novel approach but one that is grounded in a growing evidence-base.The primary objective of this research is to provide preliminary evidence of the effectiveness of tDCS…
- Conditions
- Tobacco Dependence, Smoking Cessation, Tobacco Smoking, Tobacco Use Disorder
- Trial name
- NCT03841292
- Testing
- Varenicline, Active tDCS
- Where
- Canada
- Volunteers
- 41 people
- Sponsor
- Centre for Addiction and Mental Health
Tobacco Use Disorder
Impact of Cigar Flavor in Dual Users
The purpose of this study is to understand addiction to filtered cigars (FCs) compared to cigarettes in young adults, ages 21-34, who smoke both cigarettes and cigars.
- Trial name
- NCT04487470
- Testing
- Flavored filtered cigars, Unflavored filtered cigars
- Where
- United States
- Volunteers
- 89 people, healthy volunteers welcome
- Sponsor
- UConn Health
Cigarette Addiction
Personal Vaporizer vs Cigalike
This is a pilot study to compare efficiency and tolerability of a personal vaporizers (PV) new generation electronic cigarette loaded with nicotine e-liquid with cigalike new generation electronic cigarette loaded with nicotine…
- Trial name
- VAPECIG 2 (NCT02398487)
- Testing
- cigalike with nicotine, Personal Vaporizer with nicotine
- Where
- Italy
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- University of Catania
Tobacco Use Disorder
The Effects of Memantine and Bupropion on Acute, Reinforcing, and Conditioned Effects of Cigarettes - 1
One of nicotine's effects on the body is at the level of the NMDA receptors in the brain. Memantine is a drug that also affects NMDA receptors, making it a candidate for the treatment of nicotine addiction.
- Trial name
- NCT00136747
- Testing
- Memantine, bupropion
- Where
- United States
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- New York State Psychiatric Institute
Smoking (Tobacco) Addiction, Smoking ( Cigarette)
Measuring Communal Coping in Dual-smoking Couples Making a Quit Attempt
Smoking is the leading preventable cause of death in the United States, and quitting is especially difficult for couples who both smoke.
- Conditions
- Smoking (Tobacco) Addiction, Smoking ( Cigarette), Tobacco, Tobacco Abstinence
- Trial name
- NCT07553962
- Where
- United States
- Volunteers
- 250 people
- Sponsor
- University of Colorado, Denver
Nicotine Addiction, Smoking Cessation
e-Cigarettes Versus NRT Gum for Smoking Cessation
This is a randomized trial comparing electronic cigarettes (e-Cigarettes) to nicotine gum for smoking cessation. Participants will be randomly assigned to either e-cigarette use or nicotine gum use during a quit attempt.
- Trial name
- NCT01925781
- Testing
- Nicotine polacrilex, STAM 1100mAh CE4 eGo Clearomizer
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Creighton University
Smoking
Treatment to Quit Smoking
This protocol evaluates the efficacy of combining pharmacologic treatments for smoking cessation, entailing the use of the nicotine skin patch with the nicotinic antagonist mecamylamine, with a specific behavioral therapy…
- Trial name
- NCT00018161
- Testing
- Mecamylamine, Nicotine Patch, Cigarette brand switching
- Where
- United States
- Sponsor
- US Department of Veterans Affairs
Smoking Cessation
The Effects of Cigarette Addiction on Lower Extremity Movement Speed and Coordination
This observational study will aim to investigate the effects of cigarette addiction on lower extremity motor coordination and movement speed in young adults.
- Trial name
- NCT07075068
- Testing
- Behavioral and Functional Performance Assessment Battery
- Where
- Turkey (Türkiye)
- Volunteers
- 24 people
- Sponsor
- Saglik Bilimleri Universitesi
Healthy, Nicotine Addiction
Compensatory Behavior of E-cig Users in Response to Reduced Nicotine E-liquids
The goal of this clinical trial is to learn if low nicotine eliquids work to reduce exposure to nicotine, in addicted ecig users, without increasing consumption of other harmful constituents.
- Conditions
- Healthy, Nicotine Addiction, Electronic Cigarette Use
- Trial name
- NCT06602492
- Testing
- Lower nicotine e-liquid, Higher nicotine eliquid
- Where
- United States
- Volunteers
- 72 people
- Sponsor
- Rochester Institute of Technology
Smoking, Smoking Cessation
A Study Evaluating the Use of an Indoor Air Quality Monitor to Promote a Smoke-free Home
The purpose of this study is to evaluate how using an indoor air quality monitor can promote a smoke-free home for cancer patients who are enrolled in MSK's Tobacco Treatment Program.
- Conditions
- Smoking, Smoking Cessation, Smoking Reduction, Smoking Habit
- Trial name
- NCT06693700
- Testing
- Indoor Air Quality Monitor AirGradient ONE
- Where
- 8 sites in United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Memorial Sloan Kettering Cancer Center
Nicotine Addiction, E-Cig Use
Quit Smoking Study for People Who Use E-Cigarettes
The overarching aim of this proposed randomized controlled trial (RCT) is to test nicotine replacement therapy (NRT) with text message support for two smoking cessation approaches among young adult dual users of combustible…
- Conditions
- Nicotine Addiction, E-Cig Use, Quitting Smoking
- Trial name
- NCT04946825
- Testing
- Nicotine replacement therapy patch, Nicotine replacement therapy lozenge, Quit electronic cigarettes
- Where
- United States
- Volunteers
- 396 people, healthy volunteers welcome
- Sponsor
- University of Vermont
Nicotine Dependence
Multimodal Neuroimaging Genetic Biomarkers of Nicotine AddictionSeverity
Background: Smoking is a difficult habit to quit, and some people find it more difficult to quit than others do. Nicotine is the substance in cigarettes that makes smoking so addictive.
- Trial name
- NCT01867411
- Where
- United States
- Volunteers
- 159 people, healthy volunteers welcome
- Sponsor
- National Institute on Drug Abuse (NIDA)
Addiction
Effects of Repetitive tDCS on ad Libitum Smoking Behavior: EMA and EEG Study
Bilateral (left cathodal/ right anodal) transcranial Direct Current Stimulation (tDCS) over the dorsolateral prefrontal cortex (DLPFC) seems to reduce craving and to increase the time till smoking the first cigarette after the…
- Trial name
- NCT03027687
- Testing
- tDCS
- Where
- Netherlands
- Volunteers
- 73 people, healthy volunteers welcome
- Sponsor
- Erasmus Medical Center
Smoking ( Cigarette), Smoking (Tobacco) Addiction
THE EFFECT OF A TRANSTHEORETICAL MODEL-BASED CHATBOT SUPPORT INTERVENTION ON SMOKING BEHAVIOR IN UNIVERSITY STUDENTS
The purpose of this clinical trial is to examine the impact of a chatbot-supported intervention based on the Transtheoretical Model (TTM) on smoking behavior, self-efficacy, decisional balance, and the urge to smoke among…
- Conditions
- Smoking ( Cigarette), Smoking (Tobacco) Addiction, Smoking Behaviors, Smoking Cessation
- Trial name
- NCT07887217
- Testing
- Dumansız (Transtheoretical Model-Based Chatbot Support Intervention)
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- Seher DÖNER
Nicotine Dependence, Cigarettes, Cessation, Tobacco
Reducing Nicotine Addiction in Adolescent Smokers
Adolescents are at risk for tobacco use due to factors such as impulsivity, poor perception, desire to prove themselves, and insufficient neurological development.
- Conditions
- Nicotine Dependence, Cigarettes, Cessation, Tobacco, Cessation, Smoking, Adolescent Problem Behavior
- Trial name
- NCT05477342
- Testing
- Board Game, Tobacco Cesseation Education, Combined İntervention
- Where
- Turkey (Türkiye)
- Volunteers
- 103 people, healthy volunteers welcome
- Sponsor
- Ministry of National Education, Turkey
Little Cigars and Cigarillos (LCC) Use
Little Cigar and Cigarillo Warnings for Youth
This study explores the effect of the little cigars and cigarillos (LCC) warnings on youth who currently use, have ever used, or are susceptible to using LCCs.
- Trial name
- NCT06413797
- Testing
- FDA warnings + Image, FDA Warnings Text-Only, Surgeon General Text-Only Warnings
- Where
- United States
- Volunteers
- 928 people, healthy volunteers welcome
- Sponsor
- UNC Lineberger Comprehensive Cancer Center
Smoking Cessation, Smoking (Tobacco) Addiction
PASCAL Feasibility Study
The goal of this randomized study is to assess if a conversational agent (or chatbot) that the investigators have developed to help with quitting smoking is acceptable to people trying to quit smoking and to also collect initial…
- Trial name
- NCT07301151
- Testing
- chatbot, no chatbot
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- University of Minnesota
Nicotine Dependence
Stage Ib Trial of mSMART With Varenicline
The primary aim of this study is to conduct a 60-patient feasibility, acceptability, and preliminary efficacy study of mSMART (Mobile App based Personalized Solutions and Tools for Medication Adherence of Rx Pill), a smartphone…
- Trial name
- mSMART-v (NCT03069768)
- Testing
- mSMART, Chantix
- Where
- United States
- Sponsor
- Duke University
Smoking Cessation, Smoking
Testing the Efficacy of A Scalable, Telephone-Delivered, Guided Imagery Tobacco Cessation Intervention
The objective of this R01 application is to conduct a randomized controlled trial to test the efficacy of the Be Smoke Free, telephone-based, guided imagery (GI) intervention (IC) for smoking cessation compared to active…
- Conditions
- Smoking Cessation, Smoking, Smoking Reduction, Smoking, Cigarette
- Trial name
- NCT05277831
- Testing
- Guided Imagery Intervention, Standard Behavioral Control
- Where
- United States
- Volunteers
- 1,209 people, healthy volunteers welcome
- Sponsor
- University of Arizona