Clinical trials: Cicatrix
Cesarean Scar Defect; Transvaginal Diverticulum Resection
Cesarean Section Defect Mechanism and Transvaginal Repair
Background and aims: Cesarean section defect (CSD) can cause abnormal uterine bleeding or impaired fertility, which severely impaire the quality of life in women of pregnant age.
- Trial name
- NCT05643703
- Testing
- Suture method
- Volunteers
- 300 people
- Sponsor
- Peking Union Medical College Hospital
Photodamage, Irregular Pigmentation
Comparison of the RevLite Electro-optic Q-Switched Neodymium-doped Yttrium Aluminium Garnet (EO QS Nd:YAG) Laser to a Fractionated Laser System
The purpose of this study is to compare the results of treatment between the side of the face treated with the RevLite Laser and the side of the face treated with a fractionated laser system.
- Conditions
- Photodamage, Irregular Pigmentation, Acne Scars
- Trial name
- NCT00955461
- Testing
- RevLite laser treatment, Fractionated Laser treatment
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- ConBio, a Cynosure Company
Burn Scar, Scar
Mechanistic Basis of Ablative Carbon Dioxide Laser in Treating Hypertrophic Scars
This is an observational cohort study which will look at the biomarkers from blood and tissue sample for adult patients with hypertrophic scarring due to burns/trauma incident over 12 months from date of recruitment.
- Trial name
- SMOOTH (NCT04736251)
- Where
- United Kingdom
- Volunteers
- 60 people
- Sponsor
- Naiem Moiemen
Cryotherapy Effect, Burn Scar
Observation of the Comfort and Efficacy of CO2 Laser Combined With Cryo 6 for Burn or Linear Scars.
To investigate the effect of 10,600 nm CO2 laser combined with Zimmer Cryo 6 forced cold air device on the comfort and efficacy of patients with burn scars or post-operative linear scars, and to provide a safer, more effective…
- Conditions
- Cryotherapy Effect, Burn Scar, Scar; Previous Cesarean Section
- Trial name
- NCT05555602
- Testing
- Cold-air cooling
- Where
- China
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Kaiyang Lv, MD-PhD
Acne Scars
Clinical Evaluation of Fractional Radiofrequency for the Treatment of Acne Scarring
Prospective, single centre, evaluator-blind study of the safety and performance of fractional radiofrequency (RF) for the treatment and reduction of acne scarring.
- Trial name
- NCT03767153
- Testing
- Venus Viva
- Where
- United States
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Venus Concept
Atrophic Post Acne Scarring
Comparison Between Microneedling Daycare Procedure and Tazarotene 0.1% Gel Local Application in Acne Scarring
Post acne scarring is a common complication of acne. Cosmetic appearance of the post acne facial scarring can be improved by various methods. Among the procedural methods microneedling (1) is a novel and a promising option.
- Trial name
- NCT03170596
- Testing
- tazarotene gel 0.1%, Microneedling
- Where
- India
- Volunteers
- 36 people
- Sponsor
- Post Graduate Institute of Medical Education and Research, Chandigarh
Acne Vulgaris
Treatment of Acne Scars With Erbium:Yttrium Aluminum Garnet (Er:YAG) Laser Examined Under OCT
This study is examining the effects of the 2940 nm Er:YAG on atrophic facial acne scars under optical coherence tomography in terms of blood flow, vessel shape, skin roughness, collagen content, and epidermal thickness.
- Trial name
- NCT03333759
- Testing
- Alma - Harmony XL Laser
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Miami
Scar
Evaluation of the Effect of Autologous Fat and SVF Transplantation in Promoting Mechanical-stretch Induced in Vivo Skin Regeneration
The purpose of this study is to evaluating whether autologous grafted fat transplantation or SVF transplantation is safe and/or effective to accelerating skin regeneration and soft tissue expansion.
- Trial name
- NCT02336997
- Testing
- FAT-GRAFT, SVF-TRANSPLANTATION
- Where
- 2 sites in China
- Volunteers
- 60 people
- Sponsor
- Qing-FengLi Li,MD
Cesarean Scar Defect
Impact of a Bladder Flap on Cesarean Scar Niche Development
The goal of this trial is to examine if the completion or omission of a bladder flap impacts the location and formation of cesarean scar niche in women undergoing primary cesarean section.
- Trial name
- B-FIND (NCT07634679)
- Testing
- Bladder flap formation
- Where
- 2 sites in United States
- Volunteers
- 338 people
- Sponsor
- Montefiore Medical Center
ATROPHIC ACNE SCARS
Comparison Of Outcome Of Microneedling With Autologous PRP Vs Microneedling With Topical Insulin In Treatment Of Post Acne Atrophic Scars.
Microneedling with topical INSULIN is a simple, effective tool for building body's new collagen layers and thus an alternative to all erosive techniques such as lasers, peels.
- Trial name
- NCT06002854
- Testing
- PRP( platelet rich plasma) and Insulin human
- Where
- Pakistan
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Jinnah Postgraduate Medical Centre
Cicatrix, Wound Healing
Genomic Changes Associated With the Use of Intradermal Avotermin (Juvista) in Small Wounds in Healthy Male Subjects
The purpose of this study is to further determine the safety and toleration of intradermal avotermin (Juvista), confirm accelerated healing and investigate genomic expression profiles
- Trial name
- NCT00977951
- Testing
- Intradermal avotermin
- Where
- United Kingdom
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Renovo
Ventricular Tachycardia
Stereotaxis Study To Obliterate Persistent Ventricular Tachycardia
This is a prospective, non-randomized, multi-center clinical case series evaluating the outcomes of the magnetic navigation system in ventricular tachycardia (VT) cases.
- Trial name
- STOP-VT (NCT00851279)
- Testing
- Magnetic irrigated ablation catheter
- Where
- 4 sites in United States, Czechia and 1 more
- Volunteers
- 53 people
- Sponsor
- Stereotaxis
Cesarean Scar Diverticula
Comparison of the Therapeutic Effects of VR and VR + GnRHa in the Treatment of Cesarean Scar Diverticula
Cesarean scar diverticula (CSD) is a novel recognized cause of postmenstrual abnormal uterine bleeding in women. No clinical guidelines have been issued for the management of CSD.
- Trial name
- NCT02932761
- Testing
- GnRHa, Vaginal repair of CSD
- Where
- China
- Volunteers
- 220 people
- Sponsor
- Xipeng Wang
Hypertrophic Scars, Keloids
Scar Gel Product Family Clinical Investigation
The purpose of this PMCF investigation is to determine whether there are differences between the two formulations (Dermatix and Dermatix Ultra) in improving keloid and hypertrophic scars clinical symptoms and in the overall scar…
- Trial name
- NCT07684573
- Testing
- Dermatix, Dermatix Ultra
- Volunteers
- 150 people
- Sponsor
- Hanson Medical, Inc.
Keloid
Bleomycin Jet Injections in Keloids
This is a single center, double-blind (patient and investigator), randomized, placebo-controlled study with a split-lesion design, in which selected keloids will receive three consecutive treatments of a) bleomycin and b) placebo…
- Trial name
- NCT04582305
- Testing
- Bleomycin, Normal saline
- Where
- Netherlands
- Volunteers
- 14 people
- Sponsor
- Erasmus Medical Center
Keloid, Autologus Adipose Derived Stem Cells
Autologous Adipose Derived Stem Cells Transplantation in the Treatment of Keloids.
Keloids are the most common disfiguring skin disorder affecting colored population with a prevalence of upto 16%. Autologous adipose derived stem cells have been found to have potential therapeutic benefits however limited…
- Conditions
- Keloid, Autologus Adipose Derived Stem Cells, Feasibility, Safety
- Trial name
- NCT04553159
- Testing
- Autologous adipose derived stem cells
- Where
- Uganda
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Makerere University
Diabetes Mellitus, Diabetic Nephropathy
Pirfenidone: A New Drug to Treat Kidney Disease in Patients With Diabetes
The purpose of this study is to determine whether a new investigational drug, pirfenidone, will be an effective therapy for diabetic patients with kidney dysfunction.
- Trial name
- NCT00063583
- Testing
- Pirfenidone
- Where
- 3 sites in United States
- Volunteers
- 77 people
- Sponsor
- Sharma, Kumar, M.D.
Chronic Kidney Disease
Trial of Pirfenidone to Prevent Progression in Chronic Kidney Disease
Kidney disease is a global health problem, affecting more than 10% of the world's population and more than half of adults over 70 years of age in the United States.
- Trial name
- TOP-CKD (NCT04258397)
- Testing
- Pirfenidone
- Where
- 2 sites in United States
- Volunteers
- 200 people
- Sponsor
- Veterans Medical Research Foundation
Hypertrophic Surgical Scar
Clinical Trial to Evaluate the Safety and Efficacy of Scarclinic™ Thin in Surgical Scars
Compare the efficacy and safety of Scarclinic™Thin and Scarclinic™ Normal for the treatment of surgical scars. Participant: 40 Treatment period : 3 months Medical device: Scarclinic™Thin , Scarclinic™ Normal Randomization: Table…
- Trial name
- NCT01689857
- Testing
- Scarclinic™ Thin, Scarclinic™ Normal
- Where
- South Korea
- Volunteers
- 40 people
- Sponsor
- Seoul National University Hospital
Cesarean Section; Complications, Wound, Hematoma
Effects of Scar Mobilization Versus Myofascial Cupping Technique on Cesarean Scar
Study focuses on comparing the effects of manual scar mobilization and myofascial cupping techniques on the outcomes of pain, physical characteristics, and appearance of cesarean scars.
- Trial name
- NCT06339983
- Testing
- Manual Scar Mobilization Therapy:, Myofascial Cupping Therapy:
- Where
- Pakistan
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Riphah International University