Clinical trials: Chronobiology Disorders
Circadian Rhythm Sleep Disorder, Jet Lag Type
Facilitating Adjustment to Simulated Jet Lag
The aims of this study are to compare 3 different treatments for circadian adjustment to a laboratory protocol which will mimic westward air travel across 8 time zones.
- Trial name
- NCT05382923
- Testing
- Bright Light, Bright Light + Exercise + Melatonin, Control
- Where
- United States
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- University of Arizona
Preterm, Chronobiology
The Effect of Oral Feeding Model With a Chronobiological Approach in Neonates
The ideal food for healthy term babies as well as preterm babies and sick term babies is breast milk. There are many studies showing that the composition of breast milk can vary from mother to mother, according to the baby's…
- Conditions
- Preterm, Chronobiology, Human Milk/Breastfeeding, Bottle Feeding
- Trial name
- NCT06821672
- Testing
- Chronobiological Group
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Istanbul Bilgi University
Delayed Sleep Phase Syndrome
Are Patients Suffering From DSPS Show Compromising in Everyday Functions and Abilities Before Handling the Disorder?
The purpose of this study is to determine whether the known treatment for DSPS also improve the cognitive ability and mood of the patients.
- Trial name
- NCT02962037
- Testing
- Melatonin and light therapy
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Lilach Kemer
Sleep, Circadian Dysregulation
The Impact of Artificial Sunlight on Human Sleep and Circadian Rhythms
The purpose of this study is to examine, in healthy controls, whether LED lighting that has a color spectrum similar to that of sunlight is able to differentially impact mood, circadian rhythms, sleep, and behavior, as compared…
- Conditions
- Sleep, Circadian Dysregulation, Mood
- Trial name
- NCT03636360
- Testing
- Light
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- VA Palo Alto Health Care System
Dementia, Alzheimer Disease
Multidisciplinary Expert System for the Assessment & Management of Complex Brain Disorders
The Multidisciplinary Expert System for the Assessment \& Management of Complex Brain Disorders (MES-CoBraD) is an interdisciplinary project combining Real-World Data (RWD) from multiple clinical and consumer sources through…
- Conditions
- Dementia, Alzheimer Disease, Epilepsy, Sleep Disorder
- Trial name
- MES-CoBraD (NCT05171725)
- Testing
- EEG,PSG, biosample collection (blood and CSF), neuropsychological testing
- Where
- 4 sites in Greece, Israel and 2 more
- Volunteers
- 635 people, healthy volunteers welcome
- Sponsor
- Neurological Institute of Athens
Sleep Disorders, Circadian Rhythm
Evaluation of the Effects of Pharmaton Tablets on Mental Performance and Physical Fatigue in Nurses Working Night Shift
The general aim of this study is to assess the effects of Pharmaton® Caplets on mental performance and physical fatigue in nurses and nursing auxiliaries working night shifts
- Trial name
- NCT02199847
- Testing
- Pharmaton® Caplets
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Boehringer Ingelheim
RAI1 Gene 17P11.2 Deletion+Duplication
Clinical and Molecular Biomarker Studies in RAI1 (Retinoic Acid-Induced 1) -Related Disorders
Currently, there is no clinically available genetic-based treatment for RAI1 (Retinoic Acid-Induced 1) -related disorders other than symptomatic management and there are no established clinical or molecular biomarkers that could…
- Trial name
- NCT06274164
- Testing
- Electroencephalography/Polysomnography (EEG/PSG), Skin Biopsy, Blood draw
- Where
- United States
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Baylor College of Medicine
Sleep Disorders, Circadian Rhythm
Nursing Activity and Quality of Hospitalized Patients' Sleep
This study is to determine the impact of night shift nurse's activity on patients' sleeping patterns in medical services including individual, clinical and environmental factors.
- Trial name
- SOMACTIV (NCT03370354)
- Testing
- Observational
- Volunteers
- 328 people, healthy volunteers welcome
- Sponsor
- Central Hospital, Nancy, France
Delayed Sleep Phase Syndrome
Experimental Manipulation of Sleep and Circadian Rhythms and the Role Played on Reward Function in Teens
Adolescence is a time of heightened reward sensitivity and greater impulsivity. On top of this, many teenagers experience chronic sleep deprivation and misalignment of their circadian rhythms due to biological shifts in their…
- Trial name
- CARRS-P2 (NCT04792697)
- Testing
- Increase morning bright light, Decrease evening blue light, Sleep Scheduling
- Where
- United States
- Volunteers
- 115 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Healthcare Workers, Stress Level
Effects of VR-based Respiratory Training on Motor Reaction Time and Correctness, Stress Levels, Attention, Motor Skills, Postural Stability and Sleep Quality in Shift Healthcare Workers
This study investigates the effects of virtual reality (VR)-based respiratory training on various physiological and cognitive functions in shift-working healthcare professionals, including paramedics and nurses.
- Conditions
- Healthcare Workers, Stress Level, Emergency Department, Shift Work Sleep Disorder
- Trial name
- NCT06926257
- Testing
- Experimental group (B) - breathing training using VR, Experimental group (C) - breathing training using relaxation music
- Where
- Poland
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Poznan University of Physical Education
Insomnia Disorder, Circadian Rhythm Sleep Disorder
The Sleep Clinic Outcome and Practice Study
The goal of this clinical trial is to explore the outcome and practice treatment for sleep-wake disturbances in a Sleep Clinic. The main questions it aims to answer are: What is the practice (timing and duration of treatment…
- Trial name
- SUP (NCT06669507)
- Testing
- Chronotherapy, Cognitive Behavioral Therapy for Insomnia
- Where
- Norway
- Volunteers
- 3,400 people, healthy volunteers welcome
- Sponsor
- St. Olavs Hospital
Insomnia, Circadian Rhythm Disorders
Older Adults Exercising On Time
There are indications from epidemiological cohort studies and animal experiments that timing of physical activity (also referred as "chronoactivity"), irrespective of intensity, impacts health and disease.
- Trial name
- ON TIME (NCT06613958)
- Testing
- Physical activity timing
- Where
- Netherlands
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Leiden University Medical Center
Chronobiology Disorders
Circadian Health and Influential Factors
This study evaluates the quality of sleep of patients admitted to medical and intensive care units. All of them will have a clock placed to measure their circadian activity.
- Trial name
- CHRONOHOSPI (NCT04113876)
- Where
- Spain
- Volunteers
- 975 people, healthy volunteers welcome
- Sponsor
- Instituto de Salud Carlos III
Sleep Disorders, Circadian Rhythm
Effect of Melatonin on Sleep Patterns of Resident Trainees During Night Float Shift
Anesthesiology residency requires extended and overnight shifts, which may negatively impact the quantity and quality of sleep. Previous studies have investigated the effect of night float shift work on anesthesiology resident…
- Trial name
- NCT05701969
- Testing
- Melatonin
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Virginia
Sleep Disorder, Shift-Work
Examination of the Effectiveness of Suvorexant in Improving Daytime Sleep in Shift Workers
The purpose of this study is to test the hypothesis that ingestion of the wake-inhibiting drug suvorexant 30 minutes prior to daytime sleep initiation in individuals working overnight shifts will significantly improve both…
- Trial name
- NCT02491788
- Testing
- Suvorexant
- Where
- United States
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- VA Palo Alto Health Care System
Sleep Disorders, Circadian Rhythm
Effectiveness of Combining Light and Non-Light Treatments for Jet Lag and Sleep Disorders
Jet lag and some sleep disorders are caused by a disruption in an individual's "internal clock." Understanding the most effective way to quickly re-adjust the body's internal clock will be beneficial for treating individuals with…
- Trial name
- NCT00387179
- Testing
- Melatonin, Methylxanthine, Light Therapy
- Where
- United States
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Shift Work Sleep Disorder, Shift Work Type Circadian Rhythm Sleep Disorder
Recovery and Early Sleep Tracking Using the SuperPatch REM Patch
A Phase 1 Feasibility Study of the SuperPatch REM Patch for Post-Night-Shift Sleep Recovery in NHS Doctors
- Conditions
- Shift Work Sleep Disorder, Shift Work Type Circadian Rhythm Sleep Disorder, Shift Work Sleep Disorders
- Trial name
- REST (NCT07785960)
- Testing
- SuperPatch REM Patch
- Where
- United Kingdom
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- SuperPatch Limited LLC
Shift Work Sleep Disorder
Sleepiness and Brain Function: The Effect of Armodafinil in Shift Work Sleep Disorder
The investigators hypothesize that in patients with shift work sleep disorder, armodafinil will specifically increase brain activity in the frontal cortex parallel with improvements in deficits of fundamental mechanisms of…
- Trial name
- NCT00688142
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Henry Ford Health System
Shift-Work Sleep Disorder, Shift-Work Related Sleep Disturbance
Sleep and Circadian Treatments for Shift Workers
There are three components to this study: a Field Trial, a Shift Worker Survey, and Focus Groups. The Investigators will study the effectiveness, feasibility, and acceptability of an 8-h sleep intervention in older night workers…
- Trial name
- NCT03813654
- Testing
- 8-h Afternoon-Evening Sleep, 8-h Free Sleep
- Where
- United States
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- Brigham and Women's Hospital
Sleep Apnea Syndromes, Insomnia
Evaluation of the Reliability and Validity of a Diagnostic Sleep Disorders Questionnaire
The study aims to develop and test a user-friendly, accessible approach to sleep assessment which can function as an initial "triage" of targeted sleep conditions, such as insomnia, insufficient sleep syndrome, sleep apnea…
- Conditions
- Sleep Apnea Syndromes, Insomnia, Insufficient Sleep Syndrome, Circadian Rhythm Disorders
- Trial name
- NCT03468400
- Where
- 2 sites in United States, Israel
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Dayzz Live Well Ltd.