Clinical trials: Chronic Periodontitis (Disorder)
Periodontal Disease, Chronic Neck Pain
Association Between Periodontal Disease and Chronic Neck Pain
This study investigates whether there is an association between periodontal disease (gum disease) and chronic neck pain and related functional disability.
- Trial name
- NCT07711431
- Where
- Turkey (Türkiye)
- Volunteers
- 123 people, healthy volunteers welcome
- Sponsor
- Nigde Omer Halisdemir University
Periodontitis
Photodynamic Therapy Plus Root Debridement in Gum Disease Treatment V2
Gum disease is a common disease, which affects 45% of the UK adult dentate population. It is caused by bacteria in dental plaque, which produces inflammation and a deepening of the natural crevice between the gum and the tooth…
- Trial name
- PDTV2 (NCT03270254)
- Testing
- light activated dye photodynamic therapy (PDT)
- Where
- United Kingdom
- Volunteers
- 31 people
- Sponsor
- Sheffield Teaching Hospitals NHS Foundation Trust
Chronic Periodontitis
Locally Delivered Atorvastatin & Rosuvastatin for Treatment of Furcation Defects in Chronic Periodontitis
Statins are one of the lipid lowering drugs that help in reducing cholesterol levels in the body by specifically inhibiting 3-hydroxy-3-methylglutaryl coenzyme A reductase; which is a rate limiting enzyme for cholesterol…
- Trial name
- NCT02800902
- Testing
- Rosuvastatin, Atorvastatin
- Where
- India
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Government Dental College and Research Institute, Bangalore
Dental Implantation, Missing Teeth
The Effect Of Enamel Matrix Derivatives On Gingival Tissue Thickness
Scientists do research to answer important questions which might help change or improve the way we do things in the future. The investigators know that using Enamel Matrix Derivatives results in thicker gum tissues around teeth.
- Conditions
- Dental Implantation, Missing Teeth, Periodontitis, Adult, Mucositis
- Trial name
- NCT07053969
- Testing
- Enamel Matrix Derivative
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- The University of Texas Health Science Center at San Antonio
Periodontitis, Prediabetes
Metabolic Effects of Treatment of Chronic Periodontitis in Non-diabetic Subjects
This study was aimed at assessing the effects of non-surgical periodontal treatment (NSPT) of chronic periodontitis on insulin sensitivity, glucose tolerance, and serum C-reactive protein(CRP) level amongst non-diabetic subjects.
- Trial name
- PARODIA2 (NCT02830113)
- Testing
- non-surgical periodontal treatment
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Yaounde Central Hospital
Chronic Periodontitis
Efficacy of Oral Probiotic and Antibiotic Administration in Patients With Chronic Periodontitis
The aim of this randomized placebo- controlled clinical trial is to evaluate the effects of Lactobacillus rhamnosus SP1- containing probiotic tablets and azithromycin tablets as an adjunct to scaling and root planning (SRP).
- Trial name
- NCT02839408
- Testing
- Lactobacillus rhamnosus SP1, Azithromycin, Talc powder
- Where
- Chile
- Volunteers
- 54 people
- Sponsor
- University of Chile
Chronic Periodontitis
Study on Treatment Results and Bone Changes After Replanting Severely Affected Teeth - A Before-and-After Study.
This research aims to evaluate the effectiveness of intentional replantation (IR) as a treatment for single-rooted teeth diagnosed as hopeless due to true periodontic lesions.
- Trial name
- NCT06893107
- Testing
- Intentional Replantation
- Where
- United Arab Emirates
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- University of Fujairah
Periodontal Disease, Chronic Periodontitis
Evaluation of Techniques for Scaling and Root Planing and One Stage Full Mouth Disinfection
Evaluate and compare the effectiveness in a clinical and microbial perspective one stage full-mouth disinfection technique in relation to scaling and root planing per quadrant associated with chlorhexidine or azithromycin.
- Trial name
- NCT02126267
- Testing
- Scaling and root planing, Full mouth disinfection, Chlorhexidine gel and gluconate
- Where
- Brazil
- Volunteers
- 77 people
- Sponsor
- Centro Universitario de Lavras
Chronic Periodontitis
Glucosamine Periodontal Adjunctive Therapy
This study is the first evidence based work evaluated the systemic use of glucosamine as an adjunctive therapy to closed mechanical debridement in chronic periodontitis.
- Trial name
- NCT02214095
- Testing
- glucosamine sulphate, lactose capsules
- Where
- Egypt
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Chronic Periodontitis
Evaluation of SilOss® in Periodontal Surgery
Siloss® (Azurebio, Madrid, Spain) is a synthetic and inorganic bone graft material and is composed of a dicalcium phosphate anhydrous (monetite), hydroxyapatite (HA), and amorphous silica and trace amounts of zinc.
- Trial name
- NCT02639572
- Testing
- Siloss® bone graft, Hydroxyapatitie Bone graft
- Where
- India
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- SVS Institute of Dental Sciences
Periodontitis Chronic Generalized Severe, Hyperlipidemia
Effects of Non-surgical Periodontal Therapy on Severe Periodontitis and Hyperlipidemia
This study was a single-center, non-randomized, parallel-group design clinical trial, and each group was assigned a 1:1 ratio with or without hyperlipidemia.
- Conditions
- Periodontitis Chronic Generalized Severe, Hyperlipidemia, Gingival Crevicular Fluid, Serum
- Trial name
- NCT05548933
- Testing
- non-surgical periodontal therapy
- Where
- China
- Volunteers
- 64 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Chronic Periodontitis
Influence of Stress on Non Surgical Periodontal Treatment
Treatment of periodontal diseases is influenced by several risk factors. Psychological stress is considered as one of them. Aim of this study is to assess if stress influences results of non surgical periodontal treatment in…
- Trial name
- NCT02568163
- Testing
- Non surgical periodontal treatment
- Where
- France
- Volunteers
- 72 people
- Sponsor
- University Hospital, Strasbourg, France
Chronic Periodontitis
1.2% Atorvastatin and 1.2% Simvastatin in Treatment of Chronic Periodontitis
Background: Statins are the recently evolved agents that aid in periodontal regeneration and ultimately attaining periodontal health.
- Trial name
- NCT02060032
- Testing
- 1.2% Atorvastatin local drug delivery, 1.2% simvastatin local drug delivery
- Volunteers
- 96 people
- Sponsor
- Government Dental College and Research Institute, Bangalore
Chronic Periodontitis
Relationship Between Chronic Periodontitis and Vitamin D and Calcium in Men
Objective: The objective was to evaluate whether serum vitamin D and calcium concentrations are associated with chronic periodontitis in Syrian men Methods: This study designed as "Matched Case-Control Study".200 males will be…
- Trial name
- NCT02127346
- Where
- Syria
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Damascus University
Chronic Periodontitis
Gingival Crevicular Fluid Levels of Protein Carbonyl Following the Use of Lycopene in Chronic Periodontitis
Effect of Locally Delivered Antioxidants as An Adjunct to Non-surgical Periodontal Therapy on GCF Level of Oxidative Stress Marker; Protein Carbonyl
- Trial name
- NCT03203746
- Testing
- Lycopene + SRP, SRP only
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Maie Sami tawfik
Mild and Moderate Chronic Periodontitis
Effect of Probiotic Lozenge on Gingivitis and Periodontitis
The oral cavity is mostly influenced by general health. The oral microbiota which is as complex as the gastro-intestinal or vaginal microbiota are considered to be difficult therapeutic targets.
- Trial name
- NCT02203812
- Testing
- Probiotic Arm
- Where
- India
- Volunteers
- 32 people
- Sponsor
- CD Pharma India Pvt. Ltd.
Chronic Periodontitis
A Phase II Clinical Trial of YH23537 in Patients With Chronic Periodontal Disease.
This study is designed to evaluate the efficacy and the safety of YH23537 in Korea patients with chronic periodontitis, in order to investigate the recommended therapeutic dose.
- Trial name
- NCT02585596
- Testing
- YH23537 1000mg/day, YH23537 2000mg/day, YH23537 3000mg/day
- Where
- South Korea
- Volunteers
- 275 people
- Sponsor
- Yuhan Corporation
Head and Neck Cancer, Chronic Periodontitis
Estimation of (suPAR) in Chronic Periodontitis With Post-radiotherapy on HNCs Patients
This study aims to improve a soluble urokinase plasminogen activator receptor suPAR is a reliable biomarker of chronic periodontitis and may be replaced in patients with head and neck cancer post-radiotherapy (HNC post-RT).
- Conditions
- Head and Neck Cancer, Chronic Periodontitis, Radiotherapy Side Effect
- Trial name
- HNCs (NCT06529588)
- Testing
- Radiation
- Where
- Iraq
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Al-Maarif University College
Periodontitis, Laser
Clinical Evaluation of the Effect of LANAP as an Adjunct Treatment in Management of Patients With Chronic Periodontitis
this study evaluate the effect of LANAP (Laser Assisted New Attachment Procedure) as an Adjunct Treatment in Management of Patients With Chronic Periodontitis and assay the effect of LANAP on periodontal indexes like BOP, CAL…
- Trial name
- NCT03365167
- Testing
- LANAP (Laser Assisted New Attachment Procedure), LANAP off
- Where
- Iran
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Tehran University of Medical Sciences
Cardiovascular Risk Markers, Chronic Periodontitis
Non-surgical Peridontal Treatment on Cardiovascular Risk Markers
The study evaluates the influence of non-surgical mechanical periodontal treatment in patients with severe chronic periodontitis on inflammatory markers related to risk for cardiovascular diseases
- Trial name
- NCT04540328
- Testing
- Non-surgical periodontal treatment
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Kırıkkale University