Clinical trials: Chronic Patients
COVID-19, Long COVID-19
Effects of Physiotherapy Via Telerehabilitation in Patients With COVID-19
This study aims to evaluate the effects of Physiotherapy Via Video Calls on Cardiopulmonary Functions, Physical Function, Cognitive Function, Activity Daily Livings, and Quality of Life in Patients With COVID-19.
- Conditions
- COVID-19, Long COVID-19, Cardiopulmonary Function, Physical Function
- Trial name
- NCT06251011
- Testing
- Exercise training
- Where
- Thailand
- Volunteers
- 32 people
- Sponsor
- Chulabhorn Hospital
Pulp Necroses, Apical Periodontitis
Transplantation of Allogeneic MSC in Patients With Pulp Necrosis and Chronic Apical Periodontitis
The purpose of the study is to evaluate the effect of Mesenchymal Stromal Cell (MSC) implantation on pulp and periapical regeneration of immature teeth with pulp necrosis and chronic apical periodontitis.
- Trial name
- MSC (NCT04545307)
- Testing
- Allogenic transplant of BM-MSC in a root canal from patients with immature apexes and pulpar necrosis and apical periodontitis
- Where
- Venezuela
- Volunteers
- 5 people, healthy volunteers welcome
- Sponsor
- Universidad Central de Venezuela
Chronic Hepatitis C
Study to Determine the Safety and Effectiveness of Antiviral Combination Therapy to Treat Hepatitis C Virus (HCV) in Patients Who Have Previously Not Received the Standard of Care
The purpose of the study is to determine whether therapy with the combination of PSI-7977 and daclatasvir (BMS-790052) with or without ribavirin is effective in treating hepatitis C virus (HCV) infection when given for 12 or 24…
- Trial name
- NCT01359644
- Testing
- PSI-7977, Daclatasvir, Ribavirin
- Where
- 18 sites in United States, Puerto Rico
- Volunteers
- 350 people
- Sponsor
- Bristol-Myers Squibb
COPD
The Effect on Small Airways of Addition of Theophylline as Inducer of Histone Deacilase Activity for Patients With Moderate to Severe Chronic Obstructive Pulmonary Disease (COPD), Treated With Inhaled Steroids and Long Acting Beta Agonists
Chronic obstructive pulmonary disease (COPD) is a chronic progressive respiratory disorder causing disability with an increasing burden to the patient, his family and to the health services.
- Trial name
- COPD (NCT00893009)
- Testing
- Theophylline
- Where
- Israel
- Volunteers
- 30 people
- Sponsor
- Assaf-Harofeh Medical Center
Chronic Fatigue Syndrome
A Complex Intervention for Chronically Fatigued Lymphoma Survivors
The present study is a randomized controlled trial (RCT) with an overall objective to examine the effect of an interdisciplinary complex intervention on the level of fatigue in lymphoma survivors with chronic fatigue.
- Trial name
- NCT05130099
- Testing
- Interdisciplinary complex intervention
- Where
- Norway
- Volunteers
- 150 people
- Sponsor
- Oslo University Hospital
COPD, Pulmonary Rehabilitation
Tele-based Resisted Exercise for COPD
The present study aims to investigate the effect of six weeks tele-based resisted exercises on cardiopulmonary function, quality of life, muscle strength and functioanl performance among patients with chronic obstructive…
- Conditions
- COPD, Pulmonary Rehabilitation, Telerehabilitation, Cardiopulmonary Exercise Test
- Trial name
- NCT04870632
- Testing
- Education, Video-based pulmonary rehabilitation, Booklet-based pulmonary rehabilitation
- Where
- Taiwan
- Volunteers
- 40 people
- Sponsor
- National Cheng-Kung University Hospital
Chronic Obstructive Pulmonary Disease
A Study to Assess Safety, Tolerability and Pharmacokinetics of of AZD6553 in Healthy Volunteers and Patients With Chronic Obstructive Pulmonary Disease (COPD)
AZD6553 is a new drug being developed as a possible treatment for patients with chronic obstructive pulmonary disease (COPD). COPD refers to chronic bronchitis and emphysema, a pair of two commonly co-existing diseases of the…
- Trial name
- NCT01068184
- Testing
- AZD6553
- Where
- United Kingdom
- Volunteers
- 109 people, healthy volunteers welcome
- Sponsor
- AstraZeneca
Chronic Hepatitis B
Switch or Sequential Combination Therapy of Peginterferon in Hepatitis B Patients With Longterm Entecavir Therapy
This is a multicenter, prospective cohort study to evaluate the efficacy and safety of sequential combination or switch therapy of pegylated interferon alfa-2a in chronic hepatitis B patients with low HBsAg and HBeAg titers after…
- Trial name
- NCT02589652
- Testing
- Pegylated interferon alfa-2a, Pegylated interferon alfa-2a plus Entecavir, Entecavir
- Where
- 17 sites in China
- Volunteers
- 294 people
- Sponsor
- Huashan Hospital
Stroke
Fear of Falling in Patients With Chronic Stroke
The aim of the study is to evaluate whether combining cognitive-behavioral therapy (CBT) with task-oriented balance training (TOBT) is more effective than general health education (GHE) together with TOBT in promoting fear of…
- Trial name
- NCT02937532
- Testing
- GHE + TOBT training, CBT + TOBT training
- Where
- 2 sites in Hong Kong
- Volunteers
- 89 people
- Sponsor
- The Hong Kong Polytechnic University
Hepatitis C Virus Infection, Hepatitis C Virus Infection, Response to Therapy of
HCV Reinfection in HD Patients Achieving SVR
Among the hemodialysis units, the global incidence of HCV infection ranges from 1.2% to 2.9%. Data regarding the long-term risk of reinfection among hemodialysis patients achieving SVR are limited.
- Conditions
- Hepatitis C Virus Infection, Hepatitis C Virus Infection, Response to Therapy of, Hemodialysis Complication
- Trial name
- NCT04732832
- Where
- 7 sites in Taiwan
- Volunteers
- 350 people
- Sponsor
- National Taiwan University Hospital
Low Back Pain
Effect of Thread-Embedding Acupuncture at EX-B2 Acupoint on Pain Intensity and Quality of Life in Chronic Low Back Pain
The goal of this clinical trial is to learn whether thread-embedding acupuncture (TEA) is more effective than sham thread-embedding acupuncture in treating adults with chronic low back pain.
- Trial name
- NCT07337187
- Testing
- Thread-embedding acupuncture
- Where
- Indonesia
- Volunteers
- 32 people
- Sponsor
- Universitas Indonesia
COPD, Pulmonary Disease
The Application and Analysis of HHHFNC in Walking Test of Pulmonary Rehabilitation
The aim of this study is to investigate the use heated humidified high-flow nasal cannula (HHHFNC) in pulmonary rehabilitation and analysis of cardiopulmonary parameters in adult patients.
- Conditions
- COPD, Pulmonary Disease, Rehabilitation
- Trial name
- NCT03863821
- Testing
- HHHFNC
- Where
- Taiwan
- Volunteers
- 30 people
- Sponsor
- Fu Jen Catholic University
Copd, Hypertension, Pulmonary
Lung Hyperinflation and Response to Pulmonary Vasodilator Therapy
The goal of this retrospective observational study is to evaluate if lung distension disorders can be a predictive factor of bad response to vasodilator therapy in patients with pulmonary hypertension (PH) associated with chronic…
- Conditions
- Copd, Hypertension, Pulmonary, Hyperdistention
- Trial name
- NCT06613321
- Testing
- Respiratory function tests before introduction of vasodilator therapy, 3 month follow up evaluation of response to treatment.
- Where
- France
- Volunteers
- 47 people
- Sponsor
- Central Hospital, Nancy, France
Acute Lymphoblastic Leukemia, Adult, Acute Lymphoblastic Leukemia, Pediatric
Treatment of Patients With Relapsed or Refractory CD19+ Lymphoid Disease With T Cells Expressing a Third-generation CAR
Adult patients with r/r acute lymphoblastic leukemia (ALL) (stratum I), r/r Non-Hodgkin's lymphoma (NHL) including chronic lymphocytic leukaemia (CLL), diffuse large B-cell lymphoma (DLBCL), follicular lymphoma (FL) or mantle…
- Conditions
- Acute Lymphoblastic Leukemia, Adult, Acute Lymphoblastic Leukemia, Pediatric, Chronic Lymphocytic Leukemia, Diffuse Large B Cell Lymphoma
- Trial name
- NCT03676504
- Testing
- CD19.CAR T Cells, Fludarabine, Cyclophosphamide
- Where
- 2 sites in Germany
- Volunteers
- 68 people
- Sponsor
- University Hospital Heidelberg
Kidney Failure, Chronic, Renal Disease, End-Stage
Pharmacokinetics/Pharmacodynamics of Argatroban Injection in End-Stage Renal Disease Patients Undergoing Hemodialysis
The primary goals of this investigation are to provide guidance on how to dose Argatroban in patients undergoing hemodialysis and to assess the safety and tolerability of Argatroban in hemodialysis patients.
- Trial name
- NCT00035178
- Testing
- Argatroban
- Where
- 2 sites in United States
- Volunteers
- 12 people
- Sponsor
- Texas Biotechnology Corporation
Chronic Renal Failure
Effectiveness of Pancreatic Enzymes in Patients Pancreatic Insufficient: Comparison of Two Drugs
Prove the efficacy of pancreatic enzyme Norzyme ® imported by Pharmaceutical Chemistry Laboratory Bergamo Ltda. verified by activity lipase contained in the formulation in controlling steatorrhea in 16 patients of both sexes aged…
- Trial name
- NCT01228643
- Testing
- Pancreatic enzimes, Creon ®
- Where
- Brazil
- Sponsor
- Azidus Brasil
Chronic Obstructive Pulmonary Disease, Foot Deformities
The Effect of Foot Deformities on Physical Activity, Fatigue Level and Quality of Life in Elderly COPD Patients
The aim of this study is to investigate the effects of changes in foot structure on physical activity level, fatigue and quality of life in COPD patients.
- Conditions
- Chronic Obstructive Pulmonary Disease, Foot Deformities, Quality of Life, Activity, Motor
- Trial name
- NCT04627935
- Testing
- The COPD Assessment Test, Navicular Drop Test, International Physical Activity Questionnaires (IPAQ)
- Where
- Turkey (Türkiye)
- Volunteers
- 77 people
- Sponsor
- Sultan Abdulhamid Han Training and Research Hospital, Istanbul, Turkey
Chronic Kidney Disease, Pediatric Urology
Safety of Short-course of NSAIDs in Pediatric Patients With CKD
The purpose of this study is to determine if non-steroidal anti-inflammatory (NSAID) use in the postoperative setting increases the risk of acute kidney injury (AKI) in pediatric patients with mild-to-moderate chronic kidney…
- Trial name
- NCT06860711
- Testing
- NSAIDs
- Where
- United States
- Volunteers
- 164 people
- Sponsor
- University of Colorado, Denver
Sinusitis
Xolair in Patients With Chronic Sinusitis
The purpose of this study is to determine if treatment with the anti-IgE antibody, Xolair (omalizumab), will improve objective and subjective evidence of chronic sinusitis.
- Trial name
- NCT00117611
- Where
- United States
- Volunteers
- 14 people
- Sponsor
- University of Chicago
Leukemia, Lymphocytic, Chronic, B-Cell
A Study to Confirm the Efficacy and Safety of Fludarabine Phosphate Administered in Untreated Chronic Lymphocytic Leukemia Patients With Anemia and/or Thrombocytopenia
The purpose of this study is to confirm the efficacy and safety of fludarabine phosphate administered with dose increasing in 6 cycles (1 cycle: 5 treatment days every 28 days) in untreated chronic lymphocytic leukemia (CLL)…
- Trial name
- NCT00220311
- Testing
- Fludarabine Phosphate (Fludara)
- Volunteers
- 10 people
- Sponsor
- Genzyme, a Sanofi Company