Clinical trials: Chronic Orthostatic Intolerance
Tachycardia, Chronic Orthostatic Intolerance
Treatment of Orthostatic Intolerance
This trial is designed to study the effects of various mechanistically unique medications in controlling excessive increases in heart rate with standing and in improving the symptoms of orthostatic intolerance in patients with…
- Trial name
- NCT00262470
- Testing
- Acetazolamide, Atomoxetine, NO Drug
- Where
- United States
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Satish R. Raj
Chronic Fatigue Syndrome in Adolescence, Postural Orthostatic Tachycardia Syndrome
POTS-CFS Study: Orthostatic Intolerance in the Context of Pediatric ME/CFS
Pilot-case-control study on exertion and orthostatic intolerance of adolescents with myalgic encephalomyelitis/ chronic fatigue syndrome (ME/CFS) compared to age-matched healthy controls (HC).
- Conditions
- Chronic Fatigue Syndrome in Adolescence, Postural Orthostatic Tachycardia Syndrome, Orthostatic Intolerance
- Trial name
- POTS-CFS (NCT06054958)
- Where
- Germany
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Technical University of Munich
Chronic Fatigue Syndrome, Myalgic Encephalomyelitis
Reducing Orthostatic Intolerance With Oral Rehydration in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome Patients
We and others have shown that many younger patients with Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) have orthostatic intolerance (OI), i.e., they can't tolerate prolonged standing.
- Conditions
- Chronic Fatigue Syndrome, Myalgic Encephalomyelitis, Systemic Exertion Intolerance Disease (SEID), Postural Tachycardia Syndrome (POTS)
- Trial name
- NCT02854683
- Testing
- Normal Saline, Oral Rehydration Solution
- Where
- United States
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- New York Medical College
Postural Tachycardia Syndrome, Chronic Orthostatic Intolerance
Objective Sleep Disturbances in Orthostatic Intolerance
We wish to study sleep architecture in patients with chronic orthostatic intolerance. We will test the null hypothesis that there is no difference in time during the various phases of sleep between patients and healthy control…
- Trial name
- NCT00581022
- Testing
- Polysomnography
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Satish R. Raj
Chronic Fatigue Syndrome, Orthostatic Intolerance
Autonomic Nervous System and Chronic Fatigue Syndrome
The investigators propose to test the hypothesis that the sympathetic nervous system contributes to the cardiovascular and inflammatory abnormalities present in the chronic fatigue syndrome (CFS) and, in particular in the subset…
- Conditions
- Chronic Fatigue Syndrome, Orthostatic Intolerance, Postural Tachycardia Syndrome
- Trial name
- CFS&ANS (NCT00580619)
- Testing
- Autonomic Function Testing, Saline infusions, L-NMMA trimethaphan
- Where
- United States
- Volunteers
- 170 people, healthy volunteers welcome
- Sponsor
- Vanderbilt University