Clinical trials: Chronic Insomnia Disorder
Insomnia, Sleep Disorder
Efficacy and Safety Study of Propofol Infusion for Refractory Chronic Primary Insomnia
Insomnia is a widespread condition in which approximately one-third of adults in the United States are symptomatic with 6% of the population meeting the diagnostic criteria for insomnia.
- Conditions
- Insomnia, Sleep Disorder, Dyssomnia
- Trial name
- NCT02043977
- Testing
- propofol injectable emulsion
- Where
- United States
- Volunteers
- 2 people, healthy volunteers welcome
- Sponsor
- Life Extension Foundation Inc.
Fibromyalgia (FM), Chronic Pain
Effects of Transcutaneous Auricular Vagus Nerve Stimulation on Symptom Severity, Sleep Quality, Central Sensitization, and Kinesiophobia in Fibromyalgia
Fibromyalgia is a chronic condition characterized by widespread musculoskeletal pain, fatigue, sleep disturbances, and sensitivity to touch. Current treatments often provide only partial relief.
- Trial name
- NCT07173400
- Testing
- Active Transcutaneous Auricular Vagus Nerve Stimulation (TaVNS)
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Hatice Betigul Meral
COPD, Sleep Disorders
To Study the Prevalence of Insomnia in Geriatric COPD Patients Who Are Enrolled in a Pulmonary Rehabilitation Program.
The goal for COPD patients in pulmonary rehabilitation programs is to improve the quality of life. COPD is known to be worse at night as are other respiratory problems such as CHF.
- Trial name
- NCT00346554
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Hackensack Meridian Health
Chronic Insomnia
Study for Evaluating the Efficacy of Ciprofol in Patients Under Narcotic Sleep With Chronic Insomnia
This is a single center, randomized, single blind, exploratory clinical study.About 30 patients with chronic insomnia are planned to be enrolled in this study and randomized into two groups by a ratio of 4:1 (Figure 1), with…
- Trial name
- NCT04958382
- Testing
- ciprofol, medium/long chain fat emulsion injection (C8-24Ve)
- Where
- China
- Volunteers
- 30 people
- Sponsor
- Sichuan Provincial People's Hospital
Chronic Insomnia
Implementing Cognitive Behavioral Therapy for Insomnia (SWELL): Function QUERI 3.0
Implementing Cognitive Behavioral Therapy for Insomnia with Older Veterans (SWELL): Function QUERI 3.0 aims to compare implementation approaches while also gathering information on clinical effectiveness of the EBP in its new…
- Trial name
- SWELL (NCT07216261)
- Testing
- Implementation Strategy: Foundational Arm, Implementation Strategy: REACH arm
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- VA Office of Research and Development
Chronic Insomnia
Evaluation of the Efficacy of E2R Hypnotherapy in the Management of Chronic Insomnia in Primary Care (HypERR)
In France, the treatment of chronic insomnia relies mainly on hypnotic drugs in routine care, despite the high level of iatrogenicity.
- Trial name
- HypERR (NCT06898099)
- Testing
- "Standard care" control group (without hypnosis), Experimental group: "E2R hypnosis"
- Where
- 35 sites in France
- Volunteers
- 136 people
- Sponsor
- Rennes University Hospital
Chinese Medicine, Stable Coronary Heart Disease
Xuefu-Zhuyu Capsule for the Treatment of "Qizhi Xueyu Zheng" (Qi Stagnation and Blood Stasis Syndrome)
"Xuefu-Zhuyu capsule" (XFZY) is made from a classic Fangji "Xuefu-Zhuyu Decoction" in an ancient Chinese medical book "Yi Lin Gai Cuo" by Chinese physician Wang Qingren, which is the most representative formula for the treatment…
- Conditions
- Chinese Medicine, Stable Coronary Heart Disease, Chronic Insomnia, Headache
- Trial name
- NCT04218487
- Testing
- Xuefu-Zhuyu Capsule, conventional therapy
- Where
- 12 sites in China
- Volunteers
- 720 people
- Sponsor
- Zhong Wang
Anxiety Disorders, Affective Disorders
Better Sleep in Psychiatric Care - Depression, Anxiety and Trauma, Pilot Study
Between 50-80 percent of patients in psychiatry have insomnia-type sleep problems. In addition to reduced quality of life and impaired function, sleep problems can aggravate other psychiatric problems and increase the risk of…
- Conditions
- Anxiety Disorders, Affective Disorders, PTSD, Insomnia Chronic
- Trial name
- NCT05379244
- Testing
- CBT-i
- Where
- Sweden
- Volunteers
- 18 people
- Sponsor
- Karolinska Institutet
Chronic Pain, Insomnia
Sleep, Pain and Quality of Life in Chronic Pain Patients
The interventional study will have two main aims. First, to compare two interventions aiming to improve sleep in chronic pain patients. And secondly, to study the associations of sleep, mood, chronic pain and quality of life.
- Trial name
- NCT04265586
- Testing
- Education, Web-based Cognitive Behavioural Therapy (iCBT)
- Where
- 2 sites in Finland
- Volunteers
- 554 people
- Sponsor
- Helsinki University Central Hospital
Back Pain Lower Back Chronic, Insomnia
Melatonin fOr CHronic bAck Pain (The MOCHA Trial)
According to the World Health Organization (WHO) Global Burden of Disease study, back pain is one of the conditions impacting disability the most worldwide.Pain medication use in patients with chronic back pain is substantial…
- Trial name
- MOCHA (NCT06476392)
- Testing
- Melatonin 10 MG
- Where
- Denmark
- Volunteers
- 220 people
- Sponsor
- Odense University Hospital
Chronic Insomnia
Digital Cognitive Behavioral Therapy for Insomnia for Chronic Insomnia in Breast Cancer Survivors
To explore the efficacy of dCBT-I therapy for chronic insomnia among breast cancer survivors in China, we propose to conduct a randomized, parallel controlled clinical study in breast cancer survivors using a smartphone Chinese…
- Trial name
- NCT05813392
- Testing
- Digital Cognitive Behavioral Therapy for Insomnia
- Where
- China
- Volunteers
- 264 people
- Sponsor
- Peking University First Hospital
Chronic Insomnia
Effect of Yoga in Chronic Insomnia
This study will evaluate the effect of the yoga in participants with chronic insomnia. The primary objective is to determine whether adding yoga to standard care improves insomnia severity, as measured by the Insomnia Severity…
- Trial name
- NCT07419152
- Testing
- Yoga-intervention, Stretching Exercises
- Where
- India
- Volunteers
- 72 people
- Sponsor
- All India Institute of Medical Sciences
Chronic Pain, Insomnia
Insomnia and Cognitive Performance in Chronic Pain
The aim of the present study is to examine cognitive function in a patient population with complex chronic pain to test the hypothesis that insomnia severity on its own predicts objective cognitive function, and that a…
- Trial name
- NCT03072745
- Testing
- Neuropsychological assessment
- Where
- Sweden
- Volunteers
- 22 people
- Sponsor
- Uppsala University
Renal Failure Chronic Requiring Hemodialysis, Poor Quality Sleep
BIA-Guided Dry Weight Assessment on Sleep Quality in Chronic Hemodialysis Patients
Based on many previous data proving hypervolemia in chronic hemodialysis patients could lead to sleep apnea and poor sleep quality.
- Trial name
- BEDTIME (NCT02825589)
- Testing
- BIA
- Where
- Thailand
- Volunteers
- 19 people
- Sponsor
- Mahidol University
Chronic Obstructive Pulmonary Disease
The Effects on Sleep qualıty and fatıgue Level of Foot Bath
Aims and objectives: To determine the effect of foot bath on sleep quality and fatigue level in patients with chronic obstructive pulmonary disease (COPD).
- Trial name
- NCT05668247
- Testing
- FOOT BATH
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Sevil Şahin
Chronic Kidney Disease Stage V, End-Stage Renal Disease
Autogenic Relaxation and Murottal Therapy in Hemodialysis Patients
This quasi-experimental study aims to evaluate the effect of combined autogenic relaxation and Surah Ar-Rahman murottal therapy on anxiety, sleep quality, and hemodynamic parameters in hemodialysis patients.
- Conditions
- Chronic Kidney Disease Stage V, End-Stage Renal Disease, Hemodialysis
- Trial name
- AR-MHD (NCT07412548)
- Testing
- Autogenic Relaxation and Surah Ar-Rahman Murottal Therapy, listening to dangdut music
- Where
- Indonesia
- Volunteers
- 76 people
- Sponsor
- Universitas Muhammadiyah Surakarta
Insomnia Chronic
Acupuncture in the Modulation of Peripheral Oxidative Stress Insomnia
A randomized controlled trial involving 140 subjects with (Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition) DSM-5 insomnia disorder after excluding those with other medical conditions, psychiatric disorders…
- Trial name
- NCT03447587
- Testing
- Electroacupuncture
- Where
- Hong Kong
- Volunteers
- 140 people
- Sponsor
- The Hong Kong Polytechnic University
Fibromyalgia
Efficacy of Non-invasive NESA Neuromodulation in Fibromyalgia
Fibromyalgia is a chronic condition that causes pain throughout the body, fatigue and other symptoms. Among the most common clinical symptoms are sleep and anxiety disorders.
- Trial name
- NCT05648695
- Testing
- Non-invasive Neuromodulation
- Where
- Spain
- Volunteers
- 12 people
- Sponsor
- University of Las Palmas de Gran Canaria
Chronic Insomnia Disorder, Chronic Insomnia
A Randomized, Single-Blind Study Evaluating the Efficacy and Cost-Effectiveness of Brief Behavioral Therapy for Chronic Insomnia Patients Under Medication Treatment At Nguyen Trai Hospital, Ho Chi Minh City
Insomnia disorder is considered quite common and is recognized as a risk factor for psychiatric disorders. In industrialized countries, chronic insomnia disorder is estimated to affect about 5-10% of the population, with some…
- Conditions
- Chronic Insomnia Disorder, Chronic Insomnia, BBT-I, CBT-I
- Trial name
- NCT06727916
- Testing
- BBT-I, Non BBT-I
- Volunteers
- 100 people
- Sponsor
- Nguyen Trai Hospital
End Stage Renal Failure, Hemodialysis, Fatigue
Reflexology Versus Progressive Muscle Relaxation for Fatigue in Hemodialysis Patients
The goal of this clinical trial is to compare the effects of reflexology and progressive muscle relaxation in reducing fatigue among hemodialysis patients and to determine which intervention provides greater relief from fatigue.
- Trial name
- PMR-HD (NCT07575607)
- Testing
- reflexology, progressive muscle relaxation, Control
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Cairo University