Clinical trials: Chronic Insomnia Disorder
Insomnia Chronic, Inflammation
Montmorency Cherry Supplementation, Sleep, and Inflammation
This study will test the effects of Montmorency cherry supplementation on sleep outcomes and inflammatory biomarkers.
- Trial name
- NCT05700643
- Testing
- Montmorency cherry supplement, Control
- Where
- United States
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Michigan State University
Stroke, Poor Quality Sleep
Rise & Shine: Promoting Sleep Quality in Chronic Stroke With Exercise
health problems, such as heart disease, diabetes, cognitive impairment, and dementia. After a person suffers a stroke, they often experience difficulties in getting a good night's sleep.
- Trial name
- NCT06847074
- Testing
- Multimodal Exercise, Cognitve and Social Activities
- Where
- Canada
- Volunteers
- 62 people
- Sponsor
- University of British Columbia
Sciatica, Lumbar Disc Herniation
Electroacupuncture for Insomnia in Patients With Chronic Sciatica Due to Lumbar Disc Herniation: a Randomized Controlled Trial
The goal of this clinical trial is to learn if electroacupuncture can improve sleep in people with chronic sciatica caused by lumbar disc herniation. It will also assess the safety of this treatment.
- Conditions
- Sciatica, Lumbar Disc Herniation, Insomnia
- Trial name
- NCT07576348
- Testing
- Electroacupuncture
- Volunteers
- 114 people
- Sponsor
- Shanghai Yueyang Integrated Medicine Hospital
Chronic Insomnia
DexmedetOmidine Complement Treats Chronic insOmnia and Improves Circadian Rhythm (DOCTOR)
It has been reported that dexmedetomidine, alpha-2 adrenoceptor agonist, can activate endogenous neural sleep pathways in the central nervous system.
- Trial name
- DOCTOR (NCT04635098)
- Testing
- dexmedetomidine, saline
- Where
- China
- Volunteers
- 64 people
- Sponsor
- Ruijin Hospital
High School 11th Grade Students, Absence of Any Language, Hearing, Mental or Psychological Disability
The Effect of Motivational Support Program Applied to Adolescents on Sleep Quality and Academic Achievement
It was planned as a randomized controlled experimental study with a single-blind technique, pretest-posttest control group and repetitive measurements, in order to determine the effect of motivational support program applied to…
- Conditions
- High School 11th Grade Students, Absence of Any Language, Hearing, Mental or Psychological Disability, Turkish Speaking and Understanding, Having a PUKI Index Above 5ı
- Trial name
- NCT06004778
- Testing
- Motivational Support Program, Educational support
- Where
- Turkey (Türkiye)
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Istanbul University - Cerrahpasa
Chronic Kidney Failure, Chronic Kidney Diseases
Physical Impairments in Children With Chronic Renal Failure
When the literature is examined, it is seen that the extent to which cough strength, grip strength, physical activity level and quality of life levels are affected in children with chronic kidney failure compared to healthy…
- Trial name
- NCT06981585
- Testing
- Physical Evaluations of Patients with Chronic Kidney Failure, Physical Evaluations of Healthy Children
- Where
- Turkey (Türkiye)
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Izmir Democracy University
Insomnia
Acupressure for Insomnia
The purpose of this study is to examine the effect of 6-weeks of relaxation acupressure compared to stimulating acupressure or a standard of care on sleep and daytime functioning.
- Trial name
- AcuSnooze (NCT01378793)
- Testing
- Relaxation Acupressure, Stimulating Acupressure
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- University of Michigan
Insomnia Chronic, Oppositional Defiant Disorder
SLEEP-COPE: Sleep Intervention for Oppositional Children
Children with Oppositional Defiant Disorder (ODD) are at risk for insomnia, arousal dysfunction, mood problems, and noncompliance.
- Trial name
- NCT06350292
- Testing
- SLEEP: COPE
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- University of South Florida
Diabetic Retinopathy, Macular Degeneration
Advancing Understanding of Transportation Options
This Stage II randomized, controlled, longitudinal trial seeks to assess the acceptability, feasibility, and effects of a driving decision aid use among geriatric patients and providers.
- Conditions
- Diabetic Retinopathy, Macular Degeneration, Glaucoma, Retinitis Pigmentosa
- Trial name
- AUTO (NCT04141891)
- Testing
- Driving Decision Aid, Older Drivers Website
- Where
- 3 sites in United States
- Volunteers
- 529 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Insomnia, Insomnia Chronic
An Open-label Trial to Evaluate the Safety and Efficacy of Chloral Hydrate in Patients with Severe Insomnia
The primary aim of this Real-World Evidence trial is to establish whether short-term (2 weeks) treatment of Chloral Hydrate is effective in patients with severe insomnia which is interfering with normal daily life, and where…
- Conditions
- Insomnia, Insomnia Chronic, Chloral Hydrate
- Trial name
- RESTORE (NCT06053840)
- Testing
- Chloral Hydrate
- Where
- United Kingdom
- Volunteers
- 100 people
- Sponsor
- Pharmanovia
Insomnia, Depressive Disorder, Major
Cannabinoids as a Treatment for Insomnia in Major Depression
This single-site study is a pilot, three-armed, double-blinded, placebo-controlled randomized controlled trial (RCT) that will determine the feasibility of a definitive RCT investigating the use of cannabis oil as a treatment for…
- Conditions
- Insomnia, Depressive Disorder, Major, Sleep Disorder, Depression
- Trial name
- CANMDD (NCT05041647)
- Testing
- 25:1 CBD/THC, 5:1 CBD/THC
- Where
- Canada
- Volunteers
- 14 people
- Sponsor
- St. Joseph's Healthcare Hamilton
Primary Insomnia
Study of the Insomnia in Patients With Low Back Pain
The purpose of this study is to examine whether insomnia due to chronic low back pain can improve with use of eszopiclone.
- Trial name
- NCT00365976
- Testing
- Eszopiclone
- Where
- United States
- Volunteers
- 58 people
- Sponsor
- Duke University
Insomnia, Chronic Pain
Effectiveness of Cognitive Behavioral Therapy for Insomnia in Young Adults With Chronic Pain
The aim of the Young Adult Cognitive Behavioral Therapy (YAC) study is to evaluate the effectiveness of the Delivering Online "ZZZ's with Empirical support (DOZE) app, a unique digital cognitive behavioral therapy for insomnia…
- Conditions
- Insomnia, Chronic Pain, Insomnia Due to Medical Condition
- Trial name
- YAC (NCT05137457)
- Testing
- Delivering Online "ZZZ's with Empirical support (DOZE) app, Sleep diary
- Where
- Canada
- Sponsor
- Women's College Hospital
Chronic Pain, Anxiety
Nu-V3 Non-Invasive Nerve Stimulation Device Trial for Chronic Pain, Anxiety, Depression, Sleeplessness
The Nu-V3 Clinical Study is a prospective, single-arm, open-label, multi-center study using the Nu-V3 cranial nerve stimulation treatment device in patients with chronic pain, anxiety, depression, and/or sleeplessness.
- Conditions
- Chronic Pain, Anxiety, Depression, Sleeplessness
- Trial name
- Nu-V3 (NCT05335980)
- Testing
- Nu-V3
- Where
- United States
- Volunteers
- 16 people
- Sponsor
- Nu-Life Solutions
Chronic Insomnia, Polysomnography
Alpha-s1 Casein Hydrolysate on Sleep
This study investigates the impact of Aalpha-s1 casein hydrolysate (ACH; Lactium®) on sleep quality in individuals with chronic insomnia, employing both subjective sleep profiles and objective polysomnography (PSG) recordings.
- Trial name
- NCT06199596
- Testing
- alpha-s1 casein hydrolysate, Maltodextrin
- Where
- Taiwan
- Volunteers
- 38 people
- Sponsor
- Kuang Tien General Hospital
Chronic Insomnia
Safety and Efficacy of Ramelteon in Elderly Subjects With Chronic Insomnia.
This purpose of this study is to assess the efficacy and safety of Ramelteon, once daily (QD), in elderly subjects with chronic insomnia.
- Trial name
- NCT00671294
- Where
- 18 sites in United States
- Volunteers
- 100 people
- Sponsor
- Takeda
Chronic Fatigue Syndrome, Behavioral Therapy Targeted to Sleep Problems
Behavioral Insomnia Therapy With Chronic Fatigue Syndrome
The purpose of this study is to determine how best to manage the sleep problems of people with Chronic Fatigue Syndrome. This study is being conducted to determine how improvements in sleep affect other Chronic Fatigue symptoms…
- Trial name
- NCT00540254
- Testing
- Cognitive Behavioral Therapy, Usual Care for Chronic Fatigue Syndrome (Active Control Group)
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- Duke University
Chronic Insomnia
Long-Term Efficacy and Safety of Ramelteon in Adults With Chronic Insomnia.
The purpose of this study to determine the long-term efficacy and safety of ramelteon, once daily (QD).
- Trial name
- NCT00247390
- Testing
- Ramelteon
- Where
- 48 sites in United States, Australia and 7 more
- Volunteers
- 451 people
- Sponsor
- Takeda
Chronic Insomnia
Ramelteon in Adults With Chronic Insomnia
The purpose of this study is to determine the safety and efficacy of Ramelteon, once daily (QD), in adult subjects with chronic insomnia.
- Trial name
- NCT00671567
- Testing
- Ramelteon
- Where
- 70 sites in United States
- Volunteers
- 848 people
- Sponsor
- Takeda
Insomnia Disorder, Depressive Disorder
Internet-based Cognitive Behavioral Therapy for Adolescents With Sleep Problems- a Feasibility Trial
The primary objective of this study is to test the feasibility and efficacy of Internet-delivered Cognitive Behavioral Therapy (CBT) for adolescents (13 - 17 years) with sleep problems (ICBT-I).
- Conditions
- Insomnia Disorder, Depressive Disorder, Anxiety Disorders, Pain, Chronic
- Trial name
- NCT04616157
- Testing
- ICBT-I
- Where
- Sweden
- Volunteers
- 27 people
- Sponsor
- Karolinska Institutet