Clinical trials: Chronic Graft-versus-host-disease
Chronic Urticaria
Cross-Cultural of the Validity, Reliability and Interpretability of Thai-version of Urticaria Control Test
Chronic urticaria symptoms commonly fluctuate from day by day. Consequently the clinical presentation of a patient in each visit is not representative of the current disease status.
- Trial name
- NCT02285049
- Testing
- Urticaria Control Test
- Where
- Thailand
- Volunteers
- 169 people
- Sponsor
- Mahidol University
Cerebral Palsy (CP)
A Novel Home-based Non-invasive Neuromodulation Therapy for Children and Adolescents With Cerebral Palsy
The aim of this study is to evaluate the clinical effectiveness, feasibility and acceptability of a novel home-based noninvasive neuromodulation therapy (AscenZ-IV Stimulator) that utilizes transcranial Pulse Current Stimulation…
- Trial name
- NCT06921538
- Testing
- AscenZ-IV neuromodulation device
- Where
- 2 sites in Singapore
- Volunteers
- 60 people
- Sponsor
- KK Women's and Children's Hospital
Rheumatoid Arthritis, Chronic Hepatitis B
Abatacept vs Placebo in RA Patients With Hepatitis B on Entecavir Background
The purpose of this study is to investigate whether the combination of abatacept along with entecavir (the study drugs) is safe and effective in treating symptoms related to rheumatoid arthritis (RA).
- Trial name
- RA (NCT02053727)
- Testing
- Abatacept
- Where
- United States
- Sponsor
- University of California, Los Angeles
Chronic Pain, Musculoskeletal Pain
The PROmoting Pain Self-Management (PROs) Trial: Holistic Pain Care in the Military Health System
The goal of this study is to improve pain care in the MHS by identifying effective, whole-person, non-pharmacologic interventions for persons with chronic musculoskeletal pain.
- Conditions
- Chronic Pain, Musculoskeletal Pain, Musculoskeletal Pain Disorder
- Trial name
- PROs (NCT06940986)
- Testing
- Empowered Relief, Move to Health, Usual Care as determined by primary care provider
- Where
- 5 sites in United States
- Volunteers
- 608 people
- Sponsor
- Brooke Army Medical Center
Blood Cancers, Leukemia
A Manualised Post-Traumatic Growth Intervention For People With Hematological Cancers In Greece
This clinical trial aims to determine whether a manualised group intervention for people with blood cancers can help them experience positive psychological changes following their diagnosis, known as post-traumatic growth.
- Conditions
- Blood Cancers, Leukemia, Lymphoma, Bone Marrow Transplant
- Trial name
- NCT07814170
- Testing
- A manualised post-traumatic growth intervention for people with hematological cancers
- Where
- 2 sites in Greece
- Volunteers
- 80 people
- Sponsor
- University of West Attica
ESRD, Social Behavior
SOCIABLE Seniors Optimizing Community Integration to Advance Better Living With ESRD
This research is being done to find out the best ways to help people with end stage kidney disease take care of their daily lives and improve their social functioning.
- Conditions
- ESRD, Social Behavior, Physical Disability
- Trial name
- SOCIABLE (NCT03055273)
- Testing
- SOCIABLE
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- Johns Hopkins University
Leukemia, CLL
Lenalidomide as Initial Treatment of Patients With Chronic Lymphocytic Leukemia (CLL) Age 65 and Older
Primary Objective: To assess the activity of lenalidomide in patients with previously untreated chronic lymphocytic leukemia (CLL) age 65 and older.
- Conditions
- Leukemia, CLL, Chronic Lymphocytic Leukemia, Small Lymphocytic Lymphoma
- Trial name
- NCT00535873
- Testing
- Lenalidomide
- Where
- United States
- Volunteers
- 61 people
- Sponsor
- M.D. Anderson Cancer Center
Low Back Pain, Mechanical, Biofeedback, Pain, Chronic
The Effectiveness of Two Different Feedbacks in Core Stabilization Education for Chronic Nonspecific Low Back Pain
Abstract. Insufficient motor control mechanism of transversus abdominus and multifidus muscles is the most important cause of the chronic nonspecific low back pain (CNLBP).
- Trial name
- NCT03099941
- Testing
- Biofeedback
- Volunteers
- 38 people
- Sponsor
- Istanbul University
Premenstrual Syndrome, Premenstrual Pain
The Soft Tissue Mobilization Techniques on PMS
The aim of this study is investigate the effects of progressive relaxation and myofascial release technique on blood flow velocity, pain, premenstrual symptoms and quality of life in premenstrual syndrome patients.
- Conditions
- Premenstrual Syndrome, Premenstrual Pain, Chronic Pelvic Pain
- Trial name
- NCT05836454
- Testing
- Progressive Muscle Relaxation Group:, Myofascial Release Technique Group
- Where
- Cyprus
- Volunteers
- 94 people
- Sponsor
- Eastern Mediterranean University
Chronic Disease, Quality of Life
Electronic Patient Reported Outcome (ePRO) Mobile Application Pragmatic Trial
Canadian and international health care systems require solutions on how to address the needs of a relatively small population that take up a large portion of health care resources.
- Trial name
- NCT02917954
- Testing
- ePRO Tool Intervention
- Where
- Canada
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Mount Sinai Hospital, Canada
Asthma, COPD
Differentiation of Asthma/COPD Exacerbation and Stable State Using Automated Lung Sound Analysis With LungPass Device
This observational study evaluates whether lung sound analysis with LungPass device can be used to differentiate exacerbation and stable state asthma and COPD.
- Trial name
- NCT05145894
- Testing
- Lung auscultation with LungPass device (electronic auscultation)
- Where
- Belarus
- Volunteers
- 200 people
- Sponsor
- Healthy Networks
Chronic Low Back Pain, Leg Pain
MIS MiLIF Versus Open
This study is being undertaken to compare the clinical outcomes of patients that have unilateral posterolateral lumbar interbody fusion using a traditional open approach versus the MiLIF procedure based on the MiCOR Precision…
- Trial name
- NCT00792129
- Testing
- The Atavi System
- Where
- 9 sites in United States
- Volunteers
- 113 people
- Sponsor
- Zimmer Biomet
Pulmonary Hypertension, COPD
Integrating ePReBMs From Phoenix in Respiratory Diseases
Participants with respiratory disease experience often a worsening of their condition, with increasing symptoms such as cough and shortness of breath.
- Conditions
- Pulmonary Hypertension, COPD, Interstitial Lung Disease, Healthy Volunteers
- Trial name
- NCT05827302
- Testing
- Health Gauge AI-Based Wearable Device - Model: Phoenix
- Where
- Canada
- Volunteers
- 7 people, healthy volunteers welcome
- Sponsor
- University of Alberta
Stroke
Improving Propulsion of the Paretic Leg In Chronic Stroke
Stroke survivors may have a latent, propulsive capacity of the paretic leg, that can be elicited during short, intensive gait training interventions.
- Trial name
- I-PICS (NCT04650802)
- Testing
- Gait training
- Where
- Netherlands
- Volunteers
- 29 people
- Sponsor
- Sint Maartenskliniek
Hepatitis C, Chronic
Hepatitis C Surveillance With Linkage to Care of Patients From Non-ID Departments in Jiangsu
Due to the occult nature of hepatitis C virus (HCV), it is estimated that less than 5% of people with chronic hepatitis C (CHC) infection knowing their status.
- Trial name
- NCT03772002
- Testing
- HCV screening
- Where
- 2 sites in China
- Volunteers
- 600 people
- Sponsor
- The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School
Urinary Incontinence, Urge
CAN-Stim Compared to SNS in Treatment of Urinary Urgency Incontinence With Wireless Neuromodulation Technology
This is a prospective, randomized, controlled, multi-center, study in which 150 evaluable subjects will be randomized 1:1 to receive either a Protect CAN-Stim or SNS InterStim® system.
- Trial name
- PROTECT (NCT02577302)
- Testing
- CAN-Stim - Protect CAN-Stim System, SNS - InterStim® System
- Where
- 15 sites in United States
- Volunteers
- 200 people
- Sponsor
- Uro Medical Corporation
Chronic Constipation
Effect of Propofol on Internal Anal Sphincter Pressure During ARM
Background and Aim: An anorectal manometry (ARM) is a common test in the evaluation of outlet obstruction in constipation. In children under 6 yo, anesthesia is often used for patient comfort and compliance.
- Trial name
- NCT01793753
- Testing
- Propofol
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Massachusetts General Hospital
Endometritis; Chronic, Subfertility
The FLORA-project: in Search for the Microbial Cause of Chronic Endometritis and the Most Appropriate Treatment to Obtain a Successful Pregnancy IVF/ICSI
Chronic endometritis is an inflammatory condition of the endometrium. This inflammation can negatively affect fertility and pregnancy. The pathology is frequently (+-10%) observed in women with fertility problems.
- Trial name
- FLORA (NCT05337072)
- Testing
- Microbiome study
- Where
- Belgium
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Universitair Ziekenhuis Brussel
Constipation
Probiotics for Alleviating Chronic Constipation in Adults
To investigate the clinical effects of probiotics in relieving intestinal motility and chronic constipation through regulating gut microbiota.
- Trial name
- NCT07152795
- Testing
- Probiotic
- Where
- China
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Wecare Probiotics Co., Ltd.
Recurrent Acute Pancreatitis, Chronic Pancreatitis
Simvastatin Treatment to Improve Patient-reported Outcomes in Patients With Chronic Pancreatitis
The purpose of this pilot study to examine the feasibility and acceptability of simvastatin in adults with Recurrent Acute Pancreatitis (RAP) and Chronic Pancreatitis (CP).
- Trial name
- SMV in CP (NCT05771675)
- Testing
- Simvastatin
- Where
- 5 sites in United States
- Volunteers
- 90 people
- Sponsor
- Cedars-Sinai Medical Center