Clinical trials: Chronic Functional Constipation
Cerebral Palsy, Spastic
Role Of Physical Therapy In Relieving Constipation In Children With Spastic Cerebral Palsy
This study was conducted to determine the effectiveness of Physical Therapy management in relieving constipation among Spastic Cerebral Palsy children.
- Trial name
- NCT03379038
- Testing
- Progressive Physical Therapy, Maintenance Physical Therapy
- Where
- Pakistan
- Volunteers
- 35 people
- Sponsor
- Isra University
Irritable Bowel Syndrome, Constipation
Treatment of Functional Bowel Disorders
The primary purpose for this study is to compare clinical treatments for patients with functional bowel disorders (irritable bowel syndrome, abdominal pain, painful constipation) in women.
- Conditions
- Irritable Bowel Syndrome, Constipation, Abdominal Pain, Functional Colonic Diseases
- Trial name
- NCT00006157
- Testing
- Desipramine, Cognitive Behavioral Treatment
- Where
- 2 sites in United States, Canada
- Volunteers
- 300 people
- Sponsor
- National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Chronic Functional Constipation
Effectiveness & Safety of Promelaxin® Microenemas Against Macrogol 4000 P.O. in Chronic Constipation in Children 6-48 Months
The study is aimed at the efficacy and safety evalutation of the study treatments through a 2-weeks study period and the subsequent follow-up-
- Trial name
- NCT02751411
- Testing
- micro-enema with Promelaxin, Macrogol 4000
- Where
- 4 sites in Italy
- Volunteers
- 158 people
- Sponsor
- Aboca Spa Societa' Agricola
Chronic Constipation
A Single-blind, Dose-titration Study of KWA-0711 in Patients With Chronic Constipation
The purpose of this study is to evaluate the efficacy and safety of titrated KWA-0711 dose in chronic constipation patients.
- Trial name
- NCT01938196
- Testing
- KWA-0711
- Where
- Japan
- Sponsor
- Kissei Pharmaceutical Co., Ltd.
Chronic Constipation
Administration of a Natural Molecular Complex in Functional Chronic Constipation
This is a multi-center, randomized, double-blinded placebo controlled trial to evaluate the efficacy and safety of the substance-based medical device (Sollievo Fisiolax) in the treatment of Chronic Constipation.
- Trial name
- NCT05192317
- Testing
- Sollievo Fisiolax
- Where
- 2 sites in Italy
- Volunteers
- 86 people
- Sponsor
- Aboca Spa Societa' Agricola
Chronic Osteoarthritis
OXN PR Compared to OxyPR to Demonstrate Non-inferiority in Pain & Locomotor Function & Improvement in Symptoms of Constipation in OA Subjects
The primary objectives are to demonstrate that the treatment with OXN PR tablets is non-inferior to the treatment with OxyPR with regards to analgesic efficacy and locomotor function.
- Trial name
- NCT00902837
- Testing
- Oxycodone naloxone prolonged release tablets (OXN), oxycodone prolonged release tablet, oxycodone naloxone tablet
- Where
- 36 sites in Belgium, Czechia and 4 more
- Volunteers
- 181 people
- Sponsor
- Mundipharma Research GmbH & Co KG
Chronic Functional Constipation
Comparative Study on the Efficacy of Vibrabot Capsule and Polyethylene Glycol for Chronic Functional Constipation
This is a single-center trial that enrolls 20 18 to 85-year-old patients with moderate to severe FC to study the efficacy of Vibrabot capsule (dosage: 5 capsules/week) and polyethylene glycol, as well as the mechanism of action…
- Trial name
- NCT06364111
- Testing
- Vibrabot capsule, polyethylene glycol
- Where
- China
- Volunteers
- 45 people
- Sponsor
- Beijing Tsinghua Chang Gung Hospital
Constipation - Functional
Chronic Ingestion of Fructooligosaccharide and Psyllium on Intestinal Transit in Women With Functional Constipation: A Randomized Crossover Trial
The goal of this clinical trial is to evaluate the effect of dietary fibers in the treatment of functional constipation in women. It will also assess the potential side effects associated with fiber consumption.
- Trial name
- NCT07202481
- Testing
- Psyllium powder, Fructooligosaccharide
- Where
- Brazil
- Volunteers
- 25 people
- Sponsor
- Federal University of Minas Gerais
Constipation, Constipation - Functional
The Impact of Respiratory Muscle Training and Patient Education on Chronic Constipation Outcomes
The primary aim of this study will be to determine if a respiratory muscle training program that includes both inspiratory muscle training (IMT) and expiratory muscle training (EMT), targeted at improving respiratory muscle…
- Conditions
- Constipation, Constipation - Functional, Dyssynergia
- Trial name
- NCT05823259
- Testing
- Hybrid Telehealth Program: Respiratory Muscle Training and Patient Education, Standard Physical Therapy Care
- Where
- United States
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- University of Miami
Constipation
Levofloxacin in the Treatment of Chronic Functional Constipation Associated With PIB(Peristaltic Contraction-Inhibiting Bacterium) Infection
Constipation, a prevalent clinical condition, significantly impacts patients' quality of life, yet relevant clinical trial technical guidelines have yet to be issued domestically.
- Trial name
- NCT06571097
- Testing
- Levofloxacin
- Where
- China
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Haifeng Lan
Chronic Constipation
Drinking Effect of Electrolyzed Alkaline Reduced Water on Functional Constipation
The goal of this clinical trial is to investigate drinking effect of electrolyzed hydrogen-rich alkaline reduced water (EHARW) in chronic constipation patients.
- Trial name
- NCT05734859
- Testing
- Electrolyzed Alkaline Ionizer
- Where
- South Korea
- Volunteers
- 30 people
- Sponsor
- Wonju Severance Christian Hospital
Functional Constipation, Fecal Impaction
Comparison of Efficacy & Tolerability Of PEG 4000 Versus PEG 3350+ Electrolytes for Pediatric Fecal Disimpaction
Childhood constipation is a common but serious gastrointestinal disorder prevalent worldwide. In 90-95% of children, it is of functional origin.
- Conditions
- Functional Constipation, Fecal Impaction, Constipation - Functional, Constipation Chronic Idiopathic
- Trial name
- NCT06349031
- Testing
- Administration of Polyethylene Glycol (PEG) 4000 as per treatment allocation to participants, Administration of Polyethylene Glycol (PEG) 3350 + Electrolyte as per treatment allocation to participants
- Where
- India
- Volunteers
- 100 people
- Sponsor
- Institute of Medical Sciences and SUM Hospital
Chronic Functional Constipation
Quality of Life in Children and Adolescents With Chronic Functional Constipation: Educational Action Effects
The purpose of this study is to determine if the quality of life in children and adolescents diagnosed with chronic functional constipation improves after educational activity in focus group composed by these patients' mothers.
- Trial name
- NCT01901445
- Testing
- Educational action with focal group
- Where
- Brazil
- Volunteers
- 11 people
- Sponsor
- Universidade Federal de Pernambuco
Chronic Pancreatitis, Inflammatory Bowel Diseases
Genomic Resources for Enhancing Available Therapies (GREAT1.0) Study
This is a prospective, descriptive, observational research study designed to observe and document the clinical practice by domain experts, and how the knowledge of new findings that are published in the medical literature affect…
- Conditions
- Chronic Pancreatitis, Inflammatory Bowel Diseases, Hepatitis, NASH - Nonalcoholic Steatohepatitis
- Trial name
- GREAT1 (NCT04306939)
- Testing
- venipuncture, Questionnaires, Additional Sample Collections
- Where
- United States
- Volunteers
- 120,000 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Functional Constipation (FC)
This is a Randomized, Double-blind, Placebo-controlled, Multicenter, Parallel-group Study of the Efficacy and Safety of 2 Weight-based Treatment Groups of Plecanatide Versus Placebo in Children and Adolescent Participants 6 to Less Than 18 Years of Age With FC
The goal of this clinical trial is to learn if plecanatide can treat functional constipation in children and adolescents aged 6 to less than 18 years.
- Trial name
- Trulance (NCT07723924)
- Testing
- plecanatide
- Where
- 29 sites in United States
- Volunteers
- 180 people
- Sponsor
- Bausch Health Americas, Inc.
Constipation - Functional
HyGIeaCare Procedure for Chronic Constipation
To assess the safety and clinical effectiveness of using the FDA cleared HyGIeaCare System to relieve constipation in patients not responding to standard laxative treatment.
- Trial name
- NCT03335969
- Testing
- colon irrigation
- Where
- United States
- Sponsor
- HyGIeaCare, Inc.
Constipation
Evaluation of Acacia Gum on Microbiome and Bowel Function in Participants With Chronic Constipation
Proof of concept study to investigate the impact of a food supplement consisting of Acacia gum on changes of gut microbiota and production of short chain fatty acids.
- Trial name
- NCT04382456
- Testing
- acacia gum
- Where
- Germany
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Alpinia Laudanum GmbH
Constipation Chronic Idiopathic
Evaluation of the Triple Management Program in the Management of Functional Chronic Constipation in Children
Abstract Background: Chronic constipation is a common disease in children, 3% all children visit gastroenterology clinics with different types and complains.
- Trial name
- NCT06082622
- Testing
- laxatives
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Minia University
Constipation, Irritable Bowel Syndrome
Factors Affecting Dissatisfaction to Treatments in Patients With Chronic Constipation and IBS With Constipation
Chronic constipation (CC) and Irritable Bowel Syndrome with Constipation (IBS-C) are two conditions difficult to manage because factors affecting dissatisfaction to treatments are misleading.
- Trial name
- NCT02813616
- Where
- Italy
- Volunteers
- 78 people
- Sponsor
- Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico
Constipation - Functional
Effect and Safety of the Dietary Supplement Mannite in Pediatric Patients With Chronic Functional Constipation
Functional constipation is a widely prevalent pediatric issue, with a prevalence in some studies as high as 32.2%. Treatment consists of a combination of behavioral and pharmacological interventions (mainly, administration of…
- Trial name
- MANNAPED (NCT06404853)
- Testing
- Manna
- Where
- Italy
- Volunteers
- 110 people
- Sponsor
- Azienda Ospedaliera SS. Antonio e Biagio e Cesare Arrigo di Alessandria