Clinical trials: Chronic Constipation
Constipation
The Effects of Abdominal Massage on Functional (Primary) Chronic Constipation
The aim of the present study is to investigate the efficacy of abdominal massage in patients with functional (primary) chronic constipation. The present study is designed as a randomized placebo controlled.
- Trial name
- NCT03764995
- Testing
- Standard bowel management, Abdominal massage
- Where
- Turkey (Türkiye)
- Volunteers
- 74 people
- Sponsor
- Hacettepe University
Constipation
Effectiveness of Electromagnetic Field Therapy in Chronic Constipation
This study was, randomise controlled study. The aim of this study was to determine the effect of transabdominal magnetic field therapy on constipation severity in patients with chronic functional constipation.
- Trial name
- NCT06578442
- Testing
- Magnetic Field Treatment, Standard Care Group
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Medipol University
Chronic Severe Pain
A Non-interventional, Observational Study for Quality of Life (Overall Health Assessment) in Patients With Chronic Severe Pain During Targinact® Treatment
This non-interventional, observational study evaluates the efficacy of Targinact with regard to quality of life in daily clinical practice in Belgium compared to the previous analgesic treatment.
- Trial name
- NCT01710917
- Testing
- Targinact® (oxycodon/naloxon)
- Where
- Belgium
- Volunteers
- 1,800 people
- Sponsor
- Mundipharma CVA
Chronic Constipation
Physiotherapeutic Intervention in Children With Chronic Functional Constipation
The purpose of this study is to determine whether physiotherapy is effective in the treatment of the chronic functional constipation in children.
- Trial name
- NCT00906971
- Testing
- diaphragmatic breathing, isometric training of the abdominal muscles and abdominal massage
- Where
- Brazil
- Volunteers
- 72 people
- Sponsor
- Universidade Federal de Pernambuco
Constipation Chronic Idiopathic
Effect of Abdominal Massage Versus Visceral Manipulation on Constipation
The study compares the effect of abdominal massage vs. visceral manipulation on constipation status and quality of life in adults.
- Trial name
- NCT06414525
- Testing
- abdominal massage, visceral manipulation, instructions on daily, dietary , toilet , and physical activity habits
- Where
- Egypt
- Volunteers
- 75 people
- Sponsor
- Cairo University
Chronic Constipation
Phase II Study of KWA-0711 in Patients With Chronic Constipation (CC)
The purpose of this study is to evaluate the safety and efficacy of KWA-0711 in Chronic Constipation (CC) patients.
- Trial name
- NCT02343978
- Testing
- KWA-0711
- Where
- Japan
- Volunteers
- 37 people
- Sponsor
- Kissei Pharmaceutical Co., Ltd.
Constipation Chronic Idiopathic
Do the Symptoms of Chronic Constipation Improve With a Primary Care Programme Based on Behavioural Re-education and Abdominal Massage?
Constipation is one of the most common digestive problems in today's society. In Spain, it is estimated that this condition affects between 12% and 20% of the population, being more frequent in women, contributing considerably to…
- Trial name
- NCT06359249
- Testing
- change of habits, change of habits + auto abdominal massage
- Where
- Spain
- Volunteers
- 45 people
- Sponsor
- Fundacio d'Investigacio en Atencio Primaria Jordi Gol i Gurina
Bladder Dysfunction, Bowel Dysfunction
Comparison of Transcutaneous Electrical Nerve Stimulation and Manual Therapy in Children With Cerebral Palsy
There are many studies in the literature on healthy children with lower urinary tract dysfunction (LUTD), but there are limited number of studies in children with cerebral palsy (CP) with LUTD.
- Conditions
- Bladder Dysfunction, Bowel Dysfunction, Cerebral Palsy, Neurogenic Bladder
- Trial name
- NCT05351138
- Testing
- TENS, Massage
- Where
- Turkey (Türkiye)
- Volunteers
- 54 people
- Sponsor
- Bahçeşehir University
Dyssynergic Defecation, Puborectalis Syndrome
Puborectalis Syndrome as a Phenotype of Dyssynergic Defecation in Chronic Constipation: a Comparative Study of Defecography,High-resolution Anorectal Manometry, and Pelvic Floor Ultrasound
Patients with suspected DD who met the Rome IV criteria were divided into the DD group and other types of constipation groups. The differences between the two groups were analyzed to explore the precise diagnostic scheme for DD.
- Conditions
- Dyssynergic Defecation, Puborectalis Syndrome, Impaired Rectal Evacuation
- Trial name
- NCT07683390
- Testing
- Analysis of inter-group differences
- Where
- China
- Volunteers
- 164 people
- Sponsor
- Third Military Medical University
Constipation
Efficacy and Tolerability of Cassia Fistula Plus Senna Alexandrina Miller (Sugar Free) in the Chronic Functional Constipation (CFC).
Primary Objective: To evaluate the clinical efficacy of Naturetti (jelly sugar free) To test medication on subjects who suffer chronic functional constipation in 30 days use.
- Trial name
- NCT00931853
- Testing
- SENNA+CASSIA(Naturetti)
- Where
- Brazil
- Volunteers
- 117 people, healthy volunteers welcome
- Sponsor
- Sanofi
Chronic Constipation, Diabete Mellitus
Efficacy of Linaclotide in Type II Diabetics With Chronic Constipation
Study includes 5 visits, when all basic clinical information, vital signs, symptoms, and side effects are going to be assessed at each appointment.
- Trial name
- NCT03119584
- Where
- United States
- Volunteers
- 23 people
- Sponsor
- Texas Tech University Health Sciences Center, El Paso
Chronic Constipation
Elobixibat for Chronic Constipation Without Defecation Desire
Patients of chronic constipation without defecation desire will be orally administered elobixibat 10 mg once daily before meals for 4 weeks.
- Trial name
- NCT05703464
- Testing
- Elobixibat 10mg
- Where
- Japan
- Volunteers
- 40 people
- Sponsor
- International University of Health and Welfare
Low Back Pain, Constipation
Investigation of Low Back Pain Level on Symptoms in Chronic Consipation
Consipation is the most common digestive complaint in the general population
- Trial name
- NCT06073262
- Where
- Turkey (Türkiye)
- Volunteers
- 52 people
- Sponsor
- Istanbul Medipol University Hospital
Opioid Induced Constipation
Evaluation of the Efficacy and Safety of ADL5945 for the Treatment of Opioid-induced Constipation in Adults Taking Opioid Therapy for Chronic Noncancer Pain
Morphine and related opioid analgesics are known to slow gastrointestinal (GI) motility and reduce intestinal secretion through their binding to μ opioid receptors (MORs) within the GI tract.
- Trial name
- NCT01207427
- Testing
- ADL5945 0.1 mg, ADL5945 0.25 mg
- Volunteers
- 131 people
- Sponsor
- Cubist Pharmaceuticals LLC, a subsidiary of Merck & Co., Inc. (Rahway, New Jersey USA)
Opioid-induced Constipation
Safety and Efficacy of Tegaserod in Opioid-induced Constipation in Patients With Non-cancer Pain.
This study will evaluate the safety and efficacy of Tegaserod in opioid-induced constipation in patients with non-cancer pain. Patients who enter this study PRIOR to the core study (CHTF919N2201) interim analysis receive the…
- Trial name
- NCT00414024
- Testing
- Tegaserod
- Where
- 6 sites in United States, China and 4 more
- Volunteers
- 11 people
- Sponsor
- Novartis
Constipation, Arterial Stiffness
Acute Effects of Abdominal Massage on Arterial Stiffness, Muscle Oxygenation and Exercise Capacity in Constipation
Constipation is defined as having bowel movements fewer than three times per week or experiencing subjective complaints such as a sensation of incomplete evacuation, abdominal bloating, tightness, restlessness, or discomfort…
- Conditions
- Constipation, Arterial Stiffness, Muscle Oxygenation
- Trial name
- NCT07352449
- Testing
- Abdominal massage, SphygmoCOR XCEL, Moxy Monitor
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Gazi University
Constipation
Dose-ranging Study to Assess Safety and Efficacy of SP-333 for the Treatment of Opioid-induced Constipation (OIC)
The purpose of this study is to evaluate the safety and efficacy of a range of oral SP-333 doses for the treatment of opioid-induced constipation (OIC) in adults with non-cancer pain taking opioids.
- Trial name
- OIC (NCT01983306)
- Testing
- SP-333 1 mg, SP-333 3 mg, SP-333 6 mg
- Where
- 42 sites in United States
- Volunteers
- 292 people
- Sponsor
- Bausch Health Americas, Inc.
Constipation
Prucalopride in Patients With Chronic Idiopathic Constipation
The purpose of this study is to determine whether prucalopride is safe and effective in the treatment of chronic idiopathic constipation. Hypothesis: Prucalopride given at a dose of 1 mg o.d.
- Trial name
- NCT00575614
- Testing
- prucalopride
- Volunteers
- 87 people
- Sponsor
- Movetis
Chronic Functional Constipation
The Efficacy of Long-Course Treatment Using Vibrating Capsules for Chronic Constipation
This is a single-center trial. It enrolled nine 18- to 85-year-old patients with chronic constipation to evaluate the efficacy of long-course treatment by using vibrating capsule (VC).
- Trial name
- NCT06553664
- Testing
- Treat with Vibrabot capsules for at least 7 weeks
- Where
- China
- Volunteers
- 9 people
- Sponsor
- Beijing Tsinghua Chang Gung Hospital
Pain
Oxycodone-naloxone Prolonged Release Tablets in Relieving Opioid-related Constipation
The primary objective is to demonstrate that patients taking oxycodone/naloxone prolonged release tablets have improvement in symptoms of constipation compared to subjects taking oxycodone prolonged release tablets alone.
- Trial name
- NCT00412100
- Testing
- Oxycodone naloxone prolonged release tablets (OXN)
- Sponsor
- Mundipharma Research GmbH & Co KG