Clinical trials: Chronic Back Pain
Pain, Intractable, Pain, Chronic
Intermittent vs. Continuous Dorsal Root Ganglion Stimulation
The purpose of this study is to evaluate and compare the therapeutic efficacy of intermittent Dorsal Root Ganglion Stimulation (DRG-S) to standard continuous stimulation in patients with chronic intractable pain
- Trial name
- NCT04727216
- Testing
- Dorsal Root Ganglion Stimulation (DRG-S)
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Spine and Pain Institute of New York
Chronic Low Back Pain
Case Series Evaluation of Psychodynamic Interpersonal Therapy in Chronic Low Back Pain
Many people in the world have chronic pain; this is pain which lasts more than twelve weeks. Pain can cause people to feel low in mood and change how they feel about themselves and others around them.
- Trial name
- NCT03658226
- Testing
- Psychodynamic Interpersonal Therapy (PIT)
- Where
- United Kingdom
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Charlotte Morgan
Pain, Low Back Pain
Efficacy and Safety Study of Buprenorphine HCl Buccal Film in Subjects With Low Back Pain
The purpose of this study is to determine whether buprenorphine hydrochloride (HCl) buccal film is effective and safe in the treatment of chronic low back pain (CLBP).
- Trial name
- NCT01256450
- Testing
- Buprenorphine
- Where
- 24 sites in United States
- Volunteers
- 334 people
- Sponsor
- BioDelivery Sciences International
Low Back Pain
Effects of GPR on Non-Specific Chronic Low Back Pain
Introduction: Low back pain affects approximately 18.5% of the Brazilian population in adulthood, significantly impacting the quality of life and generating substantial costs for the health system.
- Trial name
- GPRSHAM (NCT06928597)
- Testing
- Global Postural Reeducation
- Where
- Brazil
- Volunteers
- 42 people
- Sponsor
- Federal University of Bahia
Low Back Pain, Constipation
Investigation of Low Back Pain Level on Symptoms in Chronic Consipation
Consipation is the most common digestive complaint in the general population
- Trial name
- NCT06073262
- Where
- Turkey (Türkiye)
- Volunteers
- 52 people
- Sponsor
- Istanbul Medipol University Hospital
Chronic Pain
A Study on the Efficacy of Dual-Carrier-Frequency Transcranial Alternating Current Stimulation Modulating the Hippocampus for the Treatment of Chronic Non-Specific Low Back Pain
This is a single-center, randomized, double-blind, sham-controlled trial evaluating dual-carrier-frequency transcranial alternating current stimulation targeting the hippocampus in 60 patients with chronic non-specific low back…
- Trial name
- NCT07832188
- Testing
- Dual-carrier-frequency transcranial alternating current stimulation, Transcranial electrical stimulation (tES)
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Qilu Hospital of Shandong University
Interstitial Cystitis, Chronic
RADIOFREQUENCY TREATMENT OF CHRONIC PELVIC PAIN MANAGEMENT IN INTERSTITIAL CYSTITIS
Interstitial cystitis/painful bladder syndrome is a collection of symptoms that includes urinary urgency, urge incontinence, nocturia, and painful urination.
- Trial name
- NCT06256679
- Testing
- superior hypogastric plexus pulsed radiofrequency and transcutaneous tibial nerve stimulation, superior hypogastric plexus pulsed radiofrequency
- Where
- Turkey (Türkiye)
- Volunteers
- 34 people
- Sponsor
- Turkish League Against Rheumatism
Chronic Low-back Pain
Manual Therapy/Exercises vs. Physiotherapy/Back School vs. Waiting List in Patients With Chronic Low Back Pain
A randomized controlled trial for patients with chronic low back pain with two treatment arms and one waiting list control group. Primary outcome is pain intensity on VAS.
- Trial name
- NCT05843149
- Testing
- Manual Therapy/Exercises, Physiotherapy/Back School
- Where
- Germany
- Volunteers
- 6 people
- Sponsor
- Charite University, Berlin, Germany
Low Back Pain, Mechanical
Thoracic Lymphatic Pump Technique Exercises Chronic Mechanical Low Back Pain
The purpose of the study is to compare between the combined effect of thoracic lymphatic pump technique with exercises and exercises alone on pain intensity using Visual Analogue Scale (VAS), lumbar spine mobility using…
- Trial name
- NCT05568758
- Testing
- Thoracic lymphatic pump technique, Exercises (stretching and strenghtening )
- Where
- Egypt
- Volunteers
- 42 people
- Sponsor
- Cairo University
Pain, Chronic, Failed Back Surgery Syndrome
Burst Spinal Cord Stimulation (Burst-SCS) Study
Recently a new form of spinal cord stimulation therapy called burst spinal cord stimulation (Burst-SCS) is available to treat chronic pain. The goal of this study is to learn more about how Burst-SCS works to reduce chronic pain.
- Trial name
- NCT03718325
- Testing
- Burst-SCS
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- University of Michigan
Chronic Low-back Pain
The Impact of Positive, Neutral and Negative Expectation Speech on Manipulative Therapy Effects
The objective of this study will be to identify the short-term impact of positive, neutral, or negative speech on pain intensity (primary outcome).
- Trial name
- NCT05996991
- Testing
- Positive expectation speech regarding spinal manipulative therapy, Neutral expectation speech regarding spinal manipulative therapy, Negative expectation speech regarding spinal manipulative therapy
- Where
- Brazil
- Volunteers
- 60 people
- Sponsor
- Universidade Federal de Sao Carlos
Chronic Low Back Pain (CLBP), Heart Rate Variability
Autonomic Differences in Heart Rate Variability Between Healthy and Chronic Low Back Pain Subjects
This study aims to evaluate the autonomic differences in heart rate variability (HRV) between healthy individuals and those with chronic low back pain.
- Conditions
- Chronic Low Back Pain (CLBP), Heart Rate Variability, Autonomic Nervous System Dysfunction
- Trial name
- NCT06760390
- Where
- Spain
- Volunteers
- 98 people, healthy volunteers welcome
- Sponsor
- Universidad de Extremadura
Chronic Low Back Pain, Posttraumatic Stress Disorder
Exercise Maintenance in Chronic Pain and PTSD
The primary purpose of the R21 is using an experimental medicine research approach to study whether a chronic, progressive-based exercise program will help Veterans suffering from chronic low back pain (cLBP) and PTSD achieve…
- Trial name
- NCT03644927
- Testing
- Progressive exercise training, Waitlist Control
- Where
- United States
- Volunteers
- 11 people
- Sponsor
- Boston University
Chronic Low Back Pain (CLBP), Sacroiliac Joint Dysfunction
Connective Tissue Dry Needling for Low Back Pain Related to Local Posterior Superior Iliac Spine Pain
This single-blind randomized controlled trial will aim to determine the effectiveness of a connective tissue dry needling (CTDN) technique, in reducing pain and improving function in individuals with chronic mechanical low back…
- Conditions
- Chronic Low Back Pain (CLBP), Sacroiliac Joint Dysfunction, Mechanical Low Back Pain
- Trial name
- NCT07345871
- Testing
- Connective tissue dry needling, Exercise therapy
- Volunteers
- 42 people
- Sponsor
- University of Social Welfare and Rehabilitation Science
Chronic Low-back Pain (cLBP)
Effects of a Hip Flexor and Extensor Muscle Training Program in Individuals with Chronic Mechanical Low Back Pain
The goal of this clinical trial is to evaluate the effect of a physiotherapy intervention program in the lumbopelvic area in chronic low back pain patients. The main questions it aims to answer are: 1.
- Trial name
- NCT06787209
- Testing
- Program to improve lumbopelvic function., generic health care
- Where
- Spain
- Volunteers
- 50 people
- Sponsor
- Lucía Pilar Vicente Pina
Chronic Low Back Pain
Validation of the Evaluation of the Perception of Physical Activity Questionnaire Adapted to Chronic Low Back Pain
Physical exercise has a fundamental position in the chronic low back pain treatment. However, the physical activity level is often low in these patients and the adherence to the care program is not enough in the long term.
- Trial name
- EPAP-LOMB (NCT05942196)
- Where
- France
- Volunteers
- 99 people
- Sponsor
- University Hospital, Clermont-Ferrand
Chronic Nonspecific Low Back Pain
Responsiveness of Turkish Disability Questionnaires in Chronic Non-Specific Low Back Pain
This prospective observational clinimetric study aimed to compare the responsiveness of the Turkish versions of the Roland-Morris Disability Questionnaire (RMDQ), Oswestry Disability Index (ODI), and Quebec Back Pain Disability…
- Trial name
- NCT06271460
- Testing
- Standardized Physiotherapy Program
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Acibadem University
Low Back Pain, Rehabilitation Program
Oxygenation of Paravertebral Muscles During Exercise in Chronic Low Back Pain Patients
The study evaluate paraspinal aerobic metabolism of chronic low back pain patients and healthy people during an original and standardized isokinetic protocol.
- Conditions
- Low Back Pain, Rehabilitation Program, Muscular Weakness
- Trial name
- OXYLOM (NCT03055182)
- Testing
- Physical rehabilitation program
- Where
- France
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- University Hospital, Lille
Low Back Pain, Sciatica
Non-surgical Spinal Decompression in Patients With Chronic Low Back Pain
The goal of this quasi-experimental trial was to evaluate the effects of non-surgical spinal decompression on disability and pain in patients with chronic low back pain and sciatica throughout a two-month follow-up, and to…
- Conditions
- Low Back Pain, Sciatica, Lumbar Disc Herniation
- Trial name
- NCT06275750
- Testing
- Spinal decompression with BTL-6000 spinal decompression system (BTL Industries Ltd.)
- Where
- Mexico
- Volunteers
- 39 people
- Sponsor
- Hospital Civil de Guadalajara
Chronic Non Specific Mechanical Low Back Pain
Effect of Lumbar Stabilization Exercises With and Without YTWL (Scapular Stabilization Exercises) on Reducing Chronic Low Back Pain and Related Disability by Numerical Pain Rating Scale and Modified Oswestry Disability Index Respectively.
Chronic low back pain is a common problem that can make daily activities difficult. Exercises that strengthen and stabilize the lower back are commonly used to reduce pain and improve movement.
- Trial name
- A RCT (NCT07845760)
- Testing
- Lumbar Stabilization Exercises and heating pad, Scapular Stabilization Exercises (YTWL) + Lumbar Stabilization Exercises + Heating Pad
- Where
- Pakistan
- Volunteers
- 70 people
- Sponsor
- Dow University of Health Sciences