Clinical trials: Choledocholithiasis
Cholangitis; Choledocholithiasis
The Comparisons of One-stage Stone Removal in Mild and Moderate Cholangitis
In expert comment, performing the sphincterotomy for choledocholithiasis with acute cholangitis may increase bleeding and pancreatitis risks (from 2% to 10%).
- Trial name
- ERCP (NCT03754491)
- Testing
- One stage treatment for mild and moderate cholangitis with choledocholithiasis
- Where
- Taiwan
- Volunteers
- 196 people
- Sponsor
- Chang Gung Memorial Hospital
Choledocholithiasis
Prospective Evaluation of the Covered Self-expandable Metal Stents (CSEMS) for Incomplete Biliary Stone Clearance
The current standard of care for bile duct stone are endoscopic sphincterotomy and stone extraction. Placement of plastic stents is an option for incomplete biliary stone clearance.
- Trial name
- NCT01475864
- Testing
- ERCP with metal stent
- Sponsor
- University of Florida
Choledocholithiasis, Gallstone Migration
Prospective Validation of "Cholecystectomy First" Strategy for Gallstone Migration
Initial cholecystectomy with intraoperative cholangiogram, followed if required by ERCP, has been implemented at the investigators institution as the standard management strategy for patients at intermediate risk of common bile…
- Conditions
- Choledocholithiasis, Gallstone Migration, Cholecystitis, Gallstone Pancreatitis
- Trial name
- NCT02461147
- Testing
- Cholecystectomy with intraoperative cholangiogram
- Where
- Switzerland
- Volunteers
- 161 people
- Sponsor
- University Hospital, Geneva
Choledocholithiasis With Cholecystitis With Obstruction, Obstructive Jaundice
COMBO Endoscopy Oropharyngeal Airway in Sedated Endoscopic Retrograde Cholangiopancreatography for Patients
Hypoxia represents the prevailing adverse occurrence during the sedation of patients undergoing Endoscopic Retrograde Cholangiopancreatography (ERCP) with propofol.
- Conditions
- Choledocholithiasis With Cholecystitis With Obstruction, Obstructive Jaundice, Pancreatitis, Cholelithiasis
- Trial name
- NCT07012772
- Testing
- The COMBO Endoscopy Oropharyngeal Airway
- Where
- 2 sites in China
- Volunteers
- 50 people
- Sponsor
- Zhejiang University
Cholelithiasis, Choledocholithiasis
Microbiomes in Patients of Recurrent Common Bile Duct Stones
Bile duct stones is a common biliary tract disease, which is characterized by high morbidity and frequent recurrence. Endoscopic retrograde cholangiopancreatography (ERCP) is an effective therapy for common bile duct stones, and…
- Trial name
- NCT03102281
- Where
- China
- Volunteers
- 100 people
- Sponsor
- The Second Hospital of Nanjing Medical University
Periampullary Diverticula
Effect of EPBD in ERCP on the Prognosis of Patients With Choledocholithiasis Complicated With Duodenal Papillary Diverticula
The investigators hypothesized that nipple balloon dilatation could make ERCP more successful and reduce postoperative complications and mortality. So the investigators design this experiment on this assumption.
- Trial name
- EPBD (NCT04254887)
- Testing
- EPBD, EST
- Where
- China
- Volunteers
- 128 people
- Sponsor
- Renmin Hospital of Wuhan University
Biliary Stones
Non-Complex Biliary Stones DSC vs ERC
To prospectively compare non-complex biliary stone clearance using fluoroscopy/radiation-free direct solitary cholangioscopy (DSC) utilizing the SpyGlass™ system with non-complex biliary stone clearance using standard endoscopic…
- Trial name
- NCT03421340
- Testing
- DSC, ERC
- Where
- 8 sites in United States, India and 2 more
- Volunteers
- 250 people
- Sponsor
- Boston Scientific Corporation
Drainage, Laparoscopic Cholecystectomy
The Efficacy and Safety of Using Prophylactic Abdominal Drainage After Cholecystectomy
Investigators want to assess the safety and efficacy of using abdominal drainage with not using any drainage, by estimating different outcomes after laparoscopic cholecystectomy for different reasons.
- Conditions
- Drainage, Laparoscopic Cholecystectomy, Acute Cholecystitis
- Trial name
- NCT05267860
- Testing
- Prophylactic Drain
- Where
- Syria
- Volunteers
- 232 people, healthy volunteers welcome
- Sponsor
- University of Aleppo
Choledocholithiasis, Large Common Bile Duct Stone
Comparison of Endoscopic Sphincterotomy Plus Large-balloon Dilatation and Conventional Treatment for Large CBD Stones
Bile duct stone extraction is impossible after endoscopic sphincterotomy (ES) alone in approximatively 10% of cases (mostly because of stones' size).
- Trial name
- NCT02592811
- Testing
- ERCP, Endoscopic Sphincterotomy, Large Balloon Dilatation of Oddi Sphincter
- Volunteers
- 150 people
- Sponsor
- Société Française d'Endoscopie Digestive
Choledocholithiasis with Cholecystitis
For Patients with Stones in Gallbladder and Bile Duct Stones At the Same Time, Surgical Removal of the Gallbladder with the Laparoscope is Done in the Same Admission Compared to Its Removal After 6 Weeks Following Successful Removel of the Stones from the Bile Ducts by the Side View Endoscope
The goal of this clinical trial is to learn if early laparoscopic cholecystectomy is safe and feasible when performed during the same admission for patients with concomitant gallbladder and common bile duct stones after clearance…
- Trial name
- NCT06599437
- Testing
- laparoscopic cholecystectomy, Late laparoscopic cholecystectomy
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Damanhour Medical National Institute
Acute Cholangitis, Biliary Tract Infection
Comparative Efficacy Of Intraductal Antibiotic During ERCP In Acute Cholangitis
Does intraductal administration of antibiotics during endoscopic retrograde cholangiopancreatography (ERCP), in addition to standard systemic antibiotic therapy, improve clinical outcomes in patients with acute cholangitis…
- Conditions
- Acute Cholangitis, Biliary Tract Infection, Biliary Obstruction, Choledocholithiasis
- Trial name
- NCT07407491
- Testing
- Gentamicin - single dose, Distilled water
- Where
- Malaysia
- Volunteers
- 172 people
- Sponsor
- National University of Malaysia
Choledocholithiasis, Cholangiocarcinoma
Etomidate vs. Midazolam for Sedation During ERCP
Recently up-coming drug, etomidate which is a modulator of GABA(gamma-Aminobutyric acid)-A receptor has been known that it maintains the appropriate sedative levels and affects little effects on respiratory system.
- Conditions
- Choledocholithiasis, Cholangiocarcinoma, Pancreatitis, Pancreatic Cancer
- Trial name
- NCT02027311
- Testing
- Etomidate, Midazolam, Meperidine
- Where
- South Korea
- Volunteers
- 63 people
- Sponsor
- Cheju Halla General Hospital
Choledocholithiasis With Acute Cholangitis (Diagnosis), Acute Pancreatitis Due to Gallstones
Complications After Endoscopic Retrograde Cholangiopancreatography
Retrospective study to analyze benign complications and malignancy risks after ERCP with sphincterotomy. All patients who received a ERCP with sphincterotomy for a benign disease will be included.
- Trial name
- ERCP (NCT04735224)
- Volunteers
- 500 people
- Sponsor
- Juan Carlos Martín del Olmo
Cholangiocarcinoma, Cholangiopathy
Spanish Registry of Direct Cholangiopancreatoscopy by Single Operator
Endoscopic ultrasound (EUS) and endoscopic retrograde cholangiopancreatography (ERCP) remain fundamental tools for the diagnosis and treatment of many pancreatobiliary diseases.
- Conditions
- Cholangiocarcinoma, Cholangiopathy, Biliary Stricture, Choledocholithiasis
- Trial name
- NCT07064447
- Testing
- Cholangiopancreatoscopy
- Volunteers
- 260 people
- Sponsor
- Germans Trias i Pujol Hospital
Choledocholithiasis
Comparison of LCBDE vs ERCP + LC for Choledocholithiasis
Protection of Oddi's sphincter remains a huge argument especially in the long term complications like common bile duct stone recurrence or cholangitis after ERCP, which determined to destroy the sphincter of Oddi.
- Trial name
- NCT02515474
- Testing
- Laparoscopy, Endoscopy
- Where
- 12 sites in China
- Volunteers
- 1,000 people
- Sponsor
- Hepatopancreatobiliary Surgery Institute of Gansu Province
Gall Stone, Common Bile Duct Calculi
Laparoendoscopic Rendezvous for Concomitant Gall Bladder Stones and Common Bile Duct Stones
Chronic calculous cholecystitis in pediatric patients leads to choledocholithiasis in about 12% of cases. These patients require removal of stones from the common bile duct.
- Conditions
- Gall Stone, Common Bile Duct Calculi, Cholecystitis, Chronic, Choledocholithiasis
- Trial name
- LERV (NCT07008170)
- Testing
- Laparoendoscopic rendezvous
- Where
- Egypt
- Volunteers
- 80 people
- Sponsor
- Minia University
Choledocholithiasis
Left Lateral Position and Prone Position for Endoscopic Retrograde Cholangiopancreatography
Endoscopic retrograde cholangiopancreatography (ERCP) has been widely used in diagnosis and treatment of pancreaticobiliary diseases. Traditionally, ERCP has been performed in the prone position.
- Trial name
- NCT02594475
- Testing
- Endoscopic retrograde cholangiopancreatography
- Where
- South Korea
- Volunteers
- 64 people
- Sponsor
- Chuncheon Sacred Heart Hospital
Choledocholithiasis
Enhanced Recovery After Surgery Program Versus Conventional Care for Laparoscopic Common Bile Duct Exploration
Laparoscopic common bile duct exploration (LCBDE) is a minimally invasive procedure to treat common bile duct stones (CBDS). Perioperative anxiety, hunger, thirst, fatigue, pain, nausea, and vomiting can influence a patient's…
- Trial name
- NCT06630767
- Testing
- ERAS, Conventional
- Where
- 2 sites in Egypt
- Volunteers
- 228 people
- Sponsor
- South Valley University
Common Bile Duct Gallstones, Choledocholithiasis
Endoscopic Treatment of Difficult Bile Duct Stones: Spyglass + EHL x Balloon Dilation of the Papilla
This study compare 2 techniques to treat difficult bile duct stones endoscopically
- Trial name
- EHL (NCT02703077)
- Testing
- Spyglass, Balloon dilation of the papilla, EHL (electrohydraulic lithotripsy)
- Where
- Brazil
- Volunteers
- 100 people
- Sponsor
- University of Sao Paulo General Hospital
Stone - Biliary
Effect of Saline Irrigation in Reducing Choledocholithiasis Recurrence After ERCP
In this prospective study, the investigators assessed the utility of intermittent saline irrigation in reducing the recurrent rate of choledocholithiasis after the endoscopic extraction for common bile duct stones, and it does…
- Trial name
- NCT03937037
- Testing
- Saline irrigation
- Where
- China
- Volunteers
- 180 people
- Sponsor
- Hepatopancreatobiliary Surgery Institute of Gansu Province