Clinical trials: Choledocholithiasis
Gallstones, Cholelithiasis
Chinese Registry Study on Treatment of Cholecysto-Choledocholithiasis
Patients with gallstone and confirmed common bile duct stones are registered in this study. The three managements for common bile duct stones are endoscopic sphincterotomy (EST), laparoscopic common bile duct exploration (LCBDE)…
- Conditions
- Gallstones, Cholelithiasis, Cholecystolithiasis, Choledocholithiasis
- Trial name
- CREST Choles (NCT02554097)
- Testing
- endoscopic sphincterotomy, laparoscopic common bile duct exploration, laparoscopic transcystic common bile duct exploration
- Where
- China
- Volunteers
- 2,700 people
- Sponsor
- Beijing Friendship Hospital
Bile Duct Stricture, Choledocholithiasis
Prospective Study to Investigate the Frequency of Possible Bacterial Entry Into the Bloodstream (Bacteremia) and Infectious Complications Associated With the Use of the Spyglass Cholangioscopy System During ERCP (Endoscopic Retrograde Cholangiopancreatography).
The aim of this study is to prospectively evaluate the frequency of bacteremia after ERCP/cholangioscopy using the Spyglass Direct Visualization System.
- Trial name
- NCT01414400
- Testing
- Blood draw for culture
- Where
- United States
- Volunteers
- 72 people
- Sponsor
- Stanford University
Choleclithiasis, Common Bile Duct Stones
Randomized Trial of ERCP Then Laparoscopic Cholecystectomy vs. Laparoscopic Cholecystectomy Plus Laparoscopic Common Bile Duct Exploration in Patients With Likely Choledocholithiasis
Objective: We compared outcome parameters for good-risk patients with classic signs, symptoms, laboratory and abdominal imaging features of cholecystolithiasis and choledocholithiasis randomized to either LC + LCBDE or ERCP/S +…
- Trial name
- ERCP/CBDE (NCT00807729)
- Testing
- ERCP, LapCBDE
- Where
- United States
- Volunteers
- 122 people
- Sponsor
- University of California, San Francisco
Cholecystitis; Acute, Choledocholithiasis
Early MRI in Acute GallstonE Disease
This pilot study aims to determine the utility of direct Magnetic Resonance Cholangiopancreatography (MRCP) in the assessment of suspected acute gallstone disease presentations.
- Trial name
- E-MAGED (NCT03709030)
- Testing
- magnetic resonance cholangiopancreatography (MRCP)
- Where
- United Kingdom
- Volunteers
- 27 people
- Sponsor
- Perspectum
Choledocholithiasis, Bile Duct Diseases
Cholangiography Using Carbon Dioxide Versus Iodinated Contrast in ERCP
Carbon dioxide (CO2) gas is widely used for luminal insufflation during endoscopic retrograde cholangiopancreatography (ERCP) of the biliary tract.
- Conditions
- Choledocholithiasis, Bile Duct Diseases, Bile Duct Carcinoma
- Trial name
- NCT02611453
- Testing
- "Air" contrast cholangiography using carbon dioxide gas
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- University of Virginia
Choledocholithiasis
Application of Machine Learning Models to Reduce Need for Diagnostic EUS or MRCP in Patients With Intermediate Likelihood of Choledocholithiasis
Machine learning predictive model can help in stratifying heterogenous intermediate likelihood group to reduce need for EUS or MRCP in selected subgroup of patients.
- Trial name
- NCT06066372
- Where
- India
- Volunteers
- 1,000 people
- Sponsor
- Asian Institute of Gastroenterology, India
Choledocholithiasis, Cholangiopancreatography, Endoscopic Retrograde
Effect of the Sequence of Dilatation and Lithotripsy on the Treatment of Choledocholithiasis With ERCP
Choledocholithiasis is a common and frequently occurring disease in China, accounting for 15.3% ~ 31.7% of the total cholelithiasis.According to its source, can be divided into primary and secondary choledocholithiasis.For large…
- Trial name
- NCT05035433
- Testing
- First lithotripsy and then EPBD, First EPBD and then lithotripsy
- Where
- China
- Volunteers
- 480 people
- Sponsor
- Xinhua Hospital, Shanghai Jiao Tong University School of Medicine
Cholecystolithiasis, Choledocholithiasis
Feasibility and Safety of Bile Duct Clearance by Transcystic Sphincter of Oddi Balloon Dilatation
To investigate feasibility and safety of intraoperative bile duct clearance by sphincter of Oddi balloon dilatation via cystic duct at cholecystectomy. Primary endpoint: rate of successful bile duct stone clearance (feasibility).
- Conditions
- Cholecystolithiasis, Choledocholithiasis, Surgery
- Trial name
- TCPBD (NCT04737642)
- Testing
- Papillary ballon dilatation
- Where
- Switzerland
- Volunteers
- 57 people
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Cholangitis, Pancreatic Cancer
Ketamine-midazolam as a Sedative Agent in Endoscopic Retrograde Cholangiopancreatography.
Does Ketamine-Midazolam have a better efficacy and safety profile compared to Midazolam - Pethidine in Endoscopic Retrograde Cholangiopancreatography (ERCP)?
- Conditions
- Cholangitis, Pancreatic Cancer, Choledocholithiasis, Choledochal Cyst
- Trial name
- NCT06111872
- Testing
- Ketamine, Midazolam, Pethidin
- Where
- Malaysia
- Volunteers
- 90 people
- Sponsor
- National University of Malaysia
ERCP
A Prospective Study of Treating Duodenal Papillary Sphincter in Different Ways During ERCP
Endoscopic retrograde cholangiopancreatography (ERCP) is commonly performed to remove bile duct stones.Endoscopic sphincterotomy (EST), endoscopic papillary balloon dilation (EPBD), and endoscopic sphincterotomy plus balloon…
- Trial name
- NCT03416205
- Testing
- Erbao electric knife, Three-cavity incision knife, Columnar expansion balloon
- Where
- China
- Volunteers
- 450 people
- Sponsor
- Zhujiang Hospital
Choledocholithiasis, Endoscopy
Study of Endoscopic Sphincterotomy With Needle Knife Papillotome in Patients of Ampullary Impacted Stone
Using a needle knife papillotome by an experienced endoscopist, endoscopic sphincterotomies were performed in difficult cannulation cases.
- Trial name
- NCT00173368
- Volunteers
- 20 people
- Sponsor
- National Taiwan University Hospital
Acute Cholecystitis, Choledocholithiasis
Acute Cholecystitis With Concomitant Choledocholithiasis: Unicentric Study of Prevalence and Predictive Factors
The management of cholelithiasis with choledocolithiasis is extensively known, whereas for Acute Calculous Cholecystitis (ACC) with choledocolithiasis or common bile duct stones (CBDS), a common entity, there is a lack of…
- Trial name
- CHOLEPREV (NCT04739891)
- Volunteers
- 120 people
- Sponsor
- Hospital de Mataró
Cholangiocarcinoma, Choledocholithiasis; Cholangitis
Efficacy of Fistulotomy for Biliary Cannulation
Access to the main bile duct is the first step in order to perform a therapeutic maneuver for biliary diseases. Early precut has been shown to ameliorate cannulation success rate, specially in difficult cannulation cases, when…
- Conditions
- Cholangiocarcinoma, Choledocholithiasis; Cholangitis, Pancreatic Cancer, Pancreatitis
- Trial name
- NCT04037007
- Testing
- Fistulotomy - High experienced., Fistulotomy - Low experienced., Conventional (guidewire) cannulation- High experienced
- Where
- Mexico
- Volunteers
- 320 people
- Sponsor
- Coordinación de Investigación en Salud, Mexico
Choledocholithiasis
EPLBD With Limited EST vs. EPLBD for Choledocholithiasis
Endoscopic papillary balloon dilation (EPBD) for choledocholithiasis is known to be comparable to endoscopic sphincterotomy (EST) especially in cases of small stones.
- Trial name
- NCT05056506
- Testing
- EPLBD, ELPBD+ESD
- Where
- 2 sites in China
- Volunteers
- 168 people
- Sponsor
- Jianfeng Yang
Choledocholithiasis
Comparison of Papillary Balloon Dilatation Vs.Sphincterotomy for Lithotripsy in Difficult Sphincterotomy or Distal CBD Tapering
Compare endoscopic papillary balloon dilatation vs. endoscopic sphincterotomy for bile duct stones in: when sphincterotomy is difficult (periampullary diverticulum, prior sphincterotomy or Billroth II anastomosis) when there is…
- Trial name
- NCT00329888
- Testing
- Endoscopic papillary balloon dilatation, Endoscopic sphincterotomy
- Where
- Taiwan
- Sponsor
- National Taiwan University Hospital
ERCP, Choledocholithiasis
Pre-cut Versus Intentional Double Guidewire for ERCP Cannulation: Prospective, Randomized Controlled Trial
Endoscopic retrograde cholangiopancreatography (ERCP) is an indispensable therapeutic procedure in the management of a wide spectrum of pancreaticobiliary disorders, including choledocholithiasis, benign and malignant biliary…
- Conditions
- ERCP, Choledocholithiasis, Biliary Drainage, Biliary Strictures Caused by Malignant Neoplasms
- Trial name
- PRIDE (NCT07329803)
- Testing
- Precut Sphincterotomy, Double Guidewire Technique
- Volunteers
- 840 people
- Sponsor
- Asian Institute of Gastroenterology, India
Biliary Disease, Choledocholithiasis
Optimizing the Evaluation and Management of Patients With Suspected Choledocholithiasis
Choledocholithiasis (stone(s) in the common bile duct) is common. Untreated or missed, choledocholithiasis has high morbidity and mortality.
- Trial name
- NCT05141916
- Testing
- Endoscopic Retrograde Cholagiopancreatography (ERCP)
- Where
- Canada
- Volunteers
- 2,000 people
- Sponsor
- University of Calgary
Choledocholithiasis, Cholangiopancreatography, Endoscopic Retrograde
IDUS in CBD Stone Recurrence High Risk Patients
This study is designed to observed CBD stones cases with high recurrence risks applying IDUS or not during ERCP. Patients with CBD stone high recurrence risks were enrolled in this study, and prospectively randomized into IUDS…
- Conditions
- Choledocholithiasis, Cholangiopancreatography, Endoscopic Retrograde, Ultrasonography
- Trial name
- NCT06265311
- Testing
- IDUS examination
- Where
- China
- Volunteers
- 248 people
- Sponsor
- Shanghai Municipal Hospital of Traditional Chinese Medicine
Cholelithiasis Associated With Common Bile Duct Stones
Prophylactic PS Placement to Prevent Pancreatitis After Endoscopic Transpapillary GPC for Cholelithiasis With Concomitant Choledocholithiasis
In this multicenter, randomized trial, patients with cholelithiasis with concomitant choledocholithiasis based on inclusion and exclusion criteria will be randomly assigned to receive rectal indomethacin alone or the combination…
- Trial name
- NCT07495111
- Testing
- Prophylactic pancreatic stent, rectal indomethacin alone
- Where
- China
- Volunteers
- 88 people
- Sponsor
- Qilu Hospital of Shandong University
Common Bile Duct Calculi
Symbolic Regression Model To Predict Choledocholithiasis
Choledocholithiasis refers to the presence of gallstones within the common bile duct. It is proposed to look for markers that help in the diagnosis and in differentiating between retained and migrated gallstones.
- Trial name
- (SymChole) (NCT04410848)
- Testing
- To determine the diagnostic of Choledocholithiasis with symbolic regression model
- Where
- Mexico
- Volunteers
- 200 people
- Sponsor
- Hospital Universitario Dr. Jose E. Gonzalez