Clinical trials: Choice Behavior
End Stage Renal Disease
Vascular Access Choice and Outcomes in the Elderly and Very Elderly With End Stage Renal Disease in China
The purpose of the study is to evaluate the clinical outcomes and cost-effectiveness of different vascular access(arteriovenous fistula, tunneled cuffed catheter and arteriovenous graft) in the elderly and very elderly with…
- Trial name
- ACCESS-China (NCT02272374)
- Testing
- AVF creation, TCC placement, AVG creation
- Where
- China
- Volunteers
- 500 people
- Sponsor
- Shanghai Changzheng Hospital
Food Selection
Encouraging Healthy and Sustainable Dietary Substitutions
The aim of this study is to examine emerging adults' responses to dietary substitution messages about health, the environment, or both health and the environment.
- Trial name
- NCT06175026
- Testing
- Health messages, Environmental messages, Health and environmental messages
- Where
- United States
- Volunteers
- 1,753 people, healthy volunteers welcome
- Sponsor
- Stanford University
Modified K-line and Modified SC-line in MRI
Laminoplasty for Multilevel Cervical Spondylotic Myelopathy Guided by Modified K-line and Modified SC-line in MRI
This study intended to investigate the combined Impact of mK-line and mSC-line on the selection of the surgical approach and whether could be used to predict sufficient decompression of cervical spinal cord and clinical outcome…
- Trial name
- NCT06478485
- Testing
- No Intervention: MCSM
- Where
- China
- Volunteers
- 300 people
- Sponsor
- Affiliated 2 Hospital of Nantong University
Platinum-resistant Ovarian Cancer, Fallopian Tube Cancer
Phase 3 Study of Nemvaleukin Alfa in Combination With Pembrolizumab in Patients With Platinum-Resistant Epithelial Ovarian Cancer (ARTISTRY-7)
This is a Phase 3, multicenter, open-label, randomized study of nemvaleukin in combination with pembrolizumab versus protocol-specific Investigator's choice chemotherapy in patients with platinum-resistant epithelial ovarian…
- Conditions
- Platinum-resistant Ovarian Cancer, Fallopian Tube Cancer, Primary Peritoneal Cancer
- Trial name
- ARTISTRY-7 (NCT05092360)
- Testing
- Nemvaleukin and Pembrolizumab Combination, Pembrolizumab, Nemvaleukin
- Where
- 117 sites in United States, Australia and 12 more
- Volunteers
- 456 people
- Sponsor
- Mural Oncology, Inc
Medication Related Osteonecrosis of the Jaw
Best Treatment Choice for Osteonecrosis of the Jaw
BETCON is a pragmatic randomized controlled open-label multi-center study in patients with newly diagnosed stage I-II MRONJ designed to answer the question whether minimally invasive management with LPRF membranes or primary…
- Trial name
- BETCON (NCT04512638)
- Testing
- Antibiotics, Chlorhexidine mouthwash, Minimally invasive surgery with LPRF
- Where
- 4 sites in Belgium
- Volunteers
- 125 people
- Sponsor
- Tim Van den Wyngaert
Motor Activity
The Influence of Laterality on the Performance of Healthy Women in Selected Standardized Tests
The aim of the research study is to find out how the results of healthy women aged 20-24 years (inclusive) differ in the Nine Peg Test, the Purdue Pegboard Test and the Box and Block Test, depending on the laterality of the…
- Trial name
- NCT05661617
- Testing
- Nine Hole Peg Test, Purdue Pegboard Test, Box and Block Test
- Where
- Czechia
- Volunteers
- 71 people, healthy volunteers welcome
- Sponsor
- Charles University, Czech Republic
Food Labelling, Eating Behaviour
Food Menu Labelling Effects on Individuals With Eating Disorders and Other Mental Health Conditions.
Calorie labelling in out-of-home (OOH) settings was introduced by the government in England as part of a wider strategy to 'tackle obesity' (DHSC, 2020).
- Conditions
- Food Labelling, Eating Behaviour, Mental Health, Eating Disorder
- Trial name
- NCT07809295
- Testing
- Control condition, Calorie labelling, Nutri-Score labelling
- Where
- United Kingdom
- Volunteers
- 900 people, healthy volunteers welcome
- Sponsor
- University of Liverpool
Pain, Analgesia
The Influence of Music Choice on Pain Tolerance in the Context of Social Background
This study will investigate the effect of different music on the pain tolerance during an increasing electric stimulus in healthy individuals, taking social background into account.
- Trial name
- MOSART (NCT06008951)
- Testing
- Listening to music, Listening to a podcast
- Where
- Netherlands
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Markus Klimek
Diffuse Large B-cell Lymphoma
A Phase 3 Trial of Epcoritamab vs Investigator's Choice Chemotherapy in Relapsed/Refractory (R/R) Diffuse Large B-cell Lymphoma (DLBCL)
The purpose of this trial is to find out if epcoritamab, also known as EPKINLY™ and GEN3013, is safe and works well as treatment for participants with DLBCL that are not responding to treatment, have grown in size, or have come…
- Trial name
- EPCORE DLBCL-1 (NCT04628494)
- Testing
- Epcoritamab, Investigator's Choice Chemotherapy
- Where
- 186 sites in United States, Australia and 22 more
- Volunteers
- 483 people
- Sponsor
- Genmab
Gestational Diabetes, Diabetes, Gestational
Metabolic Analysis for Treatment Choice in Gestational Diabetes Mellitus
Gestational diabetes (GDM) is a significant clinical and public health burden, affecting over 400,000 pregnant women in the United States each year.
- Conditions
- Gestational Diabetes, Diabetes, Gestational, Pregnancy in Diabetes
- Trial name
- MATCh-GDM (NCT03029702)
- Testing
- Insulin, Glyburide, Metformin
- Where
- United States
- Volunteers
- 54 people
- Sponsor
- Maisa N. Feghali, MD
Breast Cancer Metastatic, BRCA 1 Gene Mutation
Assessment of the Efficacy and Safety of Olaparib Monotherapy Versus Physicians Choice Chemotherapy in the Treatment of Metastatic Breast Cancer Patients With Germline BRCA1/2 Mutations.
This open label, randomised, controlled, multi-centre phase III study will assess the efficacy and safety of single agent olaparib vs standard of care based on physician's choice of capecitabine, vinorelbine or eribulin in…
- Conditions
- Breast Cancer Metastatic, BRCA 1 Gene Mutation, BRCA 2 Gene Mutation
- Trial name
- OlympiAD (NCT02000622)
- Testing
- Olaparib, Physician's choice chemotherapy
- Where
- 171 sites in United States, Bulgaria and 17 more
- Volunteers
- 302 people
- Sponsor
- AstraZeneca
Food Preferences, Genetic Predisposition
Food Choice, Psychological Bias, and Genetic Predisposition
This project aims to assess if food choice is impacted by loss aversion (LA), and if this differs based on genetic predisposition to LA, in a UK healthy cohort.
- Conditions
- Food Preferences, Genetic Predisposition, Psychological
- Trial name
- NCT04955002
- Testing
- No intervention
- Where
- United Kingdom
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Oxford Brookes University
Contraceptive Use
Utilizing Pediatric Primary Care Connections to Advance Reproductive Health
The purpose of this study is to understand in what ways the pediatrician's office can support women's family planning by screening for contraceptive needs at each well child visit over the first 12 months of the child's life.
- Trial name
- NCT07064837
- Testing
- Conecta Familia, Contraceptive need survey
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Factors Determining Time Allocation of a Multiple-Choice Question Examination
Factors Determining Time Allocation of a MCQ Examination
The MCQ is one of the objective assessment methods. It is proper to evaluate the cognitive domain of learners with high objectivity. However, there are no definite criteria for determining the appropriate exam time.
- Trial name
- NCT06210997
- Testing
- Questionaires
- Where
- Thailand
- Volunteers
- 298 people
- Sponsor
- Suranaree University of Technology
Acute Respiratory Failure
Randomized Trial of Sedative Choice for Intubation
Among critically ill adults undergoing emergency tracheal intubation, one in five experience hypotension, cardiac arrest, or death.
- Trial name
- RSI (NCT05277896)
- Testing
- Ketamine, Etomidate
- Where
- 6 sites in United States
- Volunteers
- 2,367 people
- Sponsor
- Vanderbilt University Medical Center
HIV Care Loss to Followup
Choice-Based Support for Adults Starting or Restarting Antiretroviral Therapy in Cape Town, South Africa
Disengagement from HIV care is very common in the first year after starting or restarting antiretroviral therapy (ART). There is increasing recognition of people cycling in and out of HIV care over time people newly starting and…
- Trial name
- Zikhethele (NCT07439562)
- Testing
- In-person group support, WhatsApp group support, AI coach
- Where
- South Africa
- Volunteers
- 140 people
- Sponsor
- University of Cape Town
Palliative Care
A Pragmatic Trial of an Active Choice Nudge for Generalist or Specialist Palliative Care for Seriously Ill Inpatients
This stepped-wedge, cluster-randomized pragmatic trial among six hospitals at University of Pennsylvania Health System will test a behavioral intervention embedded within the electronic health record that nudges hospital…
- Trial name
- NCT05502861
- Testing
- Generalist + Specialist palliative care, Pre-Intervention phase
- Where
- United States
- Volunteers
- 18,884 people
- Sponsor
- University of Pennsylvania
Colorectal Cancer Screening
Outreach and Choice in Colorectal Cancer Screening
The primary objective of this clinical trial will be to compare overall colorectal cancer (CRC) screening participation between an active choice (fecal immunochemical test [FIT] or colonoscopy) and a sequential choice (FIT…
- Trial name
- NCT04940442
- Testing
- Outreach
- Where
- United States
- Volunteers
- 5,000 people
- Sponsor
- Stanford University
Diabetes, Hypertension
Pharmacy Home Adherence Reporting and Monitoring Outcomes Study
This study is a pilot test of an intervention that delivers timely diagnostic information about medication nonadherence to doctors, and then offers the services of clinical pharmacists to treat these nonadherence problems.
- Conditions
- Diabetes, Hypertension, Hypercholesterolemia
- Trial name
- PHARxMOS (NCT02306122)
- Testing
- Pharmacist calls patient unless physician cancels call, Patient nonadherence information sent to physician, Pharmacist calls patient if physician requests call
- Where
- United States
- Volunteers
- 2,697 people
- Sponsor
- Brown University
Early Breast Cancer
Innovative "Scoring System" in Breast Cancer Post Neoadiuvant Chemotherapy
Our aim is to create a Scoring System (SS) able of guaranteeing radical oncology by completely removing cancer and aesthetic outcomes in line with the needs or expectations of the patients that helps surgeons to decide the type…
- Trial name
- BreastNESSy (NCT05213403)
- Testing
- Evaluation with new scoring system
- Volunteers
- 255 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS