Clinical trials: Choice Behavior
Pulmonary Disease, Chronic Obstructive
FF/UMEC/VI Inhaler: Qualitative Analysis and Subject Preference Survey
Three main classes of inhaled treatment exist for chronic obstructive pulmonary disease (COPD): Beta2-adrenergic agonists (which may be short (SABA) or long (LABA) acting), long-acting muscarinic acetylcholine receptor…
- Trial name
- NCT03046069
- Testing
- Telephone interviews, In-person focus groups, DCE surveys- cognitive interviews
- Where
- United Kingdom
- Volunteers
- 634 people
- Sponsor
- GlaxoSmithKline
Glaucoma
24-Hour Intraocular Pressure Control With Bimatoprost/Timolol Versus Latanoprost as First Choice
The primary objective of this crossover 24-hour Intraocular Pressure (IOP) trial is to compare the control obtained after 3 months of therapy with the bimatoprost/timolol fixed combination (BTFC, Ganfort) given once in the…
- Trial name
- NCT01448837
- Testing
- Bimatoprost/Timolol, 24-hour intraocular pressure monitoring, Latanoprost, 24-hour intraocular pressure monitoring
- Where
- Greece
- Volunteers
- 37 people
- Sponsor
- Aristotle University Of Thessaloniki
Brain Activity, Appetite
Effects of Protein and Fiber at Breakfast on Appetite, Blood Sugar, and Cholesterol
The objectives of the research are to assess the effects of increased protein and fiber intake at breakfast on neural activation in brain regions associated with appetitive drive and reward-driven eating, measures of subjective…
- Conditions
- Brain Activity, Appetite, Ingestive Behavior, Glucose Control
- Trial name
- PFB (NCT02169245)
- Testing
- Dietary control of protein and fiber intake at breakfast
- Where
- 2 sites in United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Purdue University
Chronic Kidney Failure
Developing and Evaluating the Yorkshire Dialysis Decision Aid
The purpose of this research is to develop a patient decision aid in paper and web formats to help patients with chronic kidney disease make informed dialysis treatment decisions.
- Trial name
- YoDDA (NCT01671228)
- Testing
- Decision Aid, Decision aid + patient stories, Decision Aid + values task
- Where
- 6 sites in United Kingdom
- Volunteers
- 488 people
- Sponsor
- University of Leeds
Human Health in Extreme Conditions
CHOICE KERGUELEN 1: Consequences of Longterm Confinement on Immunity in the Sub-Antarctic Islands: Inclusion of Volunteers Before Departure to the Kerguelen Islands
Living for long periods in extreme environments-like Antarctic research stations or space missions-can have a significant impact on human health, especially on the immune system.
- Trial name
- NCT07065253
- Testing
- blood ponction, urines collection, hair collection
- Where
- France
- Volunteers
- healthy volunteers welcome
- Sponsor
- University Hospital, Angers
Reproductive Disorder
Interest of Morphokinetic Parameters of Early Embryonic Development in the Birth Rates in Vitro Fertilization
In France, nearly 3% of children are conceived by the technique of Assisted Reproductive Medicine, of which nearly 70% by in vitro fertilization (IVF).
- Trial name
- EMCIMO (NCT03806153)
- Testing
- Morphokinetic
- Where
- 2 sites in France
- Volunteers
- 520 people
- Sponsor
- University Hospital, Rouen
Clinical Stage III Cutaneous Melanoma AJCC v8, Clinical Stage IV Cutaneous Melanoma AJCC v8
Physician/Patient Choice of Either High-Dose Recombinant Interferon Alfa-2B or Ipilimumab, Versus Pembrolizumab in Treating Patients With Stage III-IV High Risk Melanoma That Has Been Removed by Surgery
This randomized phase III trial studies how well pembrolizumab works compared with the current standard of care, physician/patient choice of either high-dose recombinant interferon alfa-2B or ipilimumab, in treating patients with…
- Conditions
- Clinical Stage III Cutaneous Melanoma AJCC v8, Clinical Stage IV Cutaneous Melanoma AJCC v8, Metastatic Cutaneous Melanoma, Metastatic Mucosal Melanoma
- Trial name
- NCT02506153
- Testing
- Biospecimen Collection, Computed Tomography, Ipilimumab
- Where
- 576 sites in United States, Canada and 1 more
- Volunteers
- 1,301 people
- Sponsor
- National Cancer Institute (NCI)
Type 2 Diabetes Mellitus, Hypertension
Evaluation of Improved Outcomes Among Ambulatory Diabetes and/or Hypertensive Patients - an Intervention Study (CPCLINT)
The goal of this interventional study is to compare improved outcomes among diabetes and/or hypertensive patients sequel to educational intervention.
- Trial name
- CPCLINT (NCT05996601)
- Testing
- Educational intervention
- Where
- Nigeria
- Volunteers
- 400 people
- Sponsor
- University of Ibadan
Sedentary Behavior, Risk Reduction
Achievement and Adherence to Behavioral Health Goals in the Setting of Patient-Directed Goal Choice
Health care decisions should include patients' health outcome goals and care preferences so as to enable a unified set of individualized patient outcome goals, rather than disparate disease-specific goals that do not reflect…
- Trial name
- NCT04294381
- Testing
- Decision tool
- Where
- Israel
- Volunteers
- 50 people
- Sponsor
- Hadassah Medical Organization
Weight Loss, Overweight and Obesity
Choosing Healthy Activities and Lifestyle Management Through Portal Support
The study aims to randomize 250 participants to 1 of 2 arms: a.) an Active Intervention Group (based on the Look AHEAD* ILI) or b.) a Comparison Group (based on the Look AHEAD DSE Comparison group) to test the hypothesis that a…
- Conditions
- Weight Loss, Overweight and Obesity, Behavior, Health
- Trial name
- CHAMPS (NCT05410353)
- Testing
- Active Intervention Group, Comparison Group
- Where
- United States
- Volunteers
- 229 people, healthy volunteers welcome
- Sponsor
- University of Tennessee
Dementia, Psychiatric Disorders Mood
Genetic Evaluation for Medication Selection (GEMS) Study
Investigators propose to determine whether knowing details about how a person's genes affect the way medicines work in the brain and body will help doctors pick more effective or safer medicine for that person.
- Conditions
- Dementia, Psychiatric Disorders Mood, Behavior Disorders
- Trial name
- GEMS (NCT03736057)
- Testing
- Delayed results of pharmacogenomic results
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- University of Alabama at Birmingham
Obesity
Nighttime Macronutrient Choice and Combined Resistance and High-intensity Interval Training
Obesity is recognized as a major public health concern because of its link to potential fatal complications arising from metabolic and cardiovascular diseases.
- Trial name
- NCT01830946
- Testing
- Whey Protein, Combined Resistance and High-Intensity Interval training, Casein Protein
- Where
- United States
- Volunteers
- 59 people, healthy volunteers welcome
- Sponsor
- Florida State University
Metastatic Breast Cancer
A Study of DB-1303/BNT323 vs Investigator's Choice Chemotherapy in HER2-Low, Hormone Receptor Positive Metastatic Breast Cancer (DYNASTY-Breast02)
The goal of this clinical trial is to assess the efficacy of DB-1303/BNT323 compared with investigator's choice chemotherapy in terms of progression-free survival (PFS) by blinded independent central review (BICR) in the HR+…
- Trial name
- NCT06018337
- Testing
- DB-1303/BNT323, Capecitabine, Paclitaxel
- Where
- 258 sites in United States, Argentina and 15 more
- Volunteers
- 541 people
- Sponsor
- DualityBio Inc.
Infertility
Medically Assisted Procreation and Choice of the Embryo: How Far Would French People Like to go
In today's context of bioethics laws revision concerning Medically Assisted Procreation, the investigators focus on the opinion of couples resorting to In Vitro Fertilization on a fundamental, much debated issue ; the choice of…
- Trial name
- NCT04763551
- Where
- France
- Volunteers
- 300 people
- Sponsor
- University Hospital, Montpellier
Venous Thrombosis or Pulmonary Embolism
What Treatment for Patients With Phlebitis or Pulmonary Embolism ?
The objective of the "anticoagchoice" study is to analyze the preferences of people suffering from phlebitis, in terms of anticoagulant, to improve adherence to these treatments, to adapt the medical prescriptions.
- Trial name
- AntiCoagChoice (NCT03889457)
- Testing
- anticoagulation choice
- Where
- France
- Volunteers
- 1,000 people
- Sponsor
- Rennes University Hospital
Palliative Care
A Pragmatic Trial of an Active Choice Nudge for Generalist or Specialist Palliative Care for Seriously Ill Inpatients
This stepped-wedge, cluster-randomized pragmatic trial among six hospitals at University of Pennsylvania Health System will test a behavioral intervention embedded within the electronic health record that nudges hospital…
- Trial name
- NCT05502861
- Testing
- Generalist + Specialist palliative care, Pre-Intervention phase
- Where
- United States
- Volunteers
- 18,884 people
- Sponsor
- University of Pennsylvania
Food Preferences, Genetic Predisposition
Food Choice, Psychological Bias, and Genetic Predisposition
This project aims to assess if food choice is impacted by loss aversion (LA), and if this differs based on genetic predisposition to LA, in a UK healthy cohort.
- Conditions
- Food Preferences, Genetic Predisposition, Psychological
- Trial name
- NCT04955002
- Testing
- No intervention
- Where
- United Kingdom
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Oxford Brookes University
Recurrent or Metastatic Cervical Cancer
JSKN033 Versus Investigator's Choice of Chemotherapy in Recurrent or Metastatic Cervical Cancer
This study is a randomized, open-label, controlled, phase III study to evaluate the efficacy and safety of JSKN033 versus investigator's choice of chemotherapy in patients with recurrent or metastatic cervical cancer who have…
- Trial name
- NCT07797153
- Testing
- JSKN033, Docetaxel, Topotecan
- Where
- 2 sites in China
- Volunteers
- 368 people
- Sponsor
- Jiangsu Alphamab Biopharmaceuticals Co., Ltd
Neonatal Screening
Parent Education and Choice About Newborn Screening and Bloodspot Retention
To address the content, timing, efficacy, and impact of prenatal education about newborn screening generally and sample retention specifically.
- Trial name
- NCT02676245
- Testing
- Viewing Newborn Screening movie, Viewing Residual Dried Blood Spot movie
- Volunteers
- 664 people
- Sponsor
- University of Utah
Food Selection
Satiety Response of White and Brown Rice Compared to Glucose Control
The investigators hypothesize that consumption of either white or brown rice will be more satiating than glucose control.
- Trial name
- NCT01508975
- Testing
- White Rice, Brown Rice, Glucose
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Minnesota