Clinical trials: Chinese Population
Metabolic Disease, Nutrition Disorders
Observational Study on a Chinese Population
An observational study was conducted in a health examination center to distinguish risk factors for health in a randomly recruited volunteers of Chinese population.
- Conditions
- Metabolic Disease, Nutrition Disorders, Genetic Predisposition to Disease
- Trial name
- NCT03406234
- Testing
- No intervention.
- Where
- China
- Volunteers
- 2,650 people, healthy volunteers welcome
- Sponsor
- Shenzhen Center for Chronic Disease Control
High-normal Blood Pressure
Study of Antihypertensive Treatment and Cardiovascular Risk in Chinese Prehypertensive Population
I. Research Objectives Primary Objectives: To evaluate the effect of low-dose antihypertensive therapy on the incidence of new-onset hypertension and new-onset diabetes in individuals with high-normal blood pressure and…
- Trial name
- NCT07652567
- Testing
- Telmisartan, Indapamide
- Where
- China
- Volunteers
- 690 people
- Sponsor
- Qilu Hospital of Shandong University
Acute Coronary Syndrome
Low-dose PCSK9 Inhibitor Combined With Stains on Serum Lipids in Chinese Population With Acute Coronary Syndrome
A total of 100 patients aged 18-85 years old with a definite diagnosis of ACS were admitted to the Department of Cardiovascular, The First Affiliated Hospital of Nanjing Medical University.
- Trial name
- NCT05298475
- Testing
- Statin, PCSK9 inhibitor
- Where
- China
- Volunteers
- 100 people
- Sponsor
- The First Affiliated Hospital with Nanjing Medical University
Gout, Hyperuricemia
A Dose Finding Study to Assess Efficacy and Safety of IBI128 in Chinese Gout Subjects
IBI128 (Tigulixostat) is a novel non-purine selective inhibitor of xanthine oxidase (XO). The XO inhibitors lower uric acid concentrations in serum by inhibiting the production of uric acid.
- Trial name
- NCT06501534
- Testing
- Febuxostat, IBI128
- Where
- China
- Volunteers
- 84 people
- Sponsor
- Innovent Biologics (Suzhou) Co. Ltd.
Breast Cancer, Quality of Life
RWE About QOL and Compliance of Patients With OFS in China
The purpose of this study is to assess the patient's feedback from using GnRHa depot formulation in postoperative, premenopausal patients with hormone receptor-positive breast cancer.
- Conditions
- Breast Cancer, Quality of Life, Hormone Receptor-positive Breast Cancer
- Trial name
- NCT05122377
- Testing
- 3M GnRHa, 1M GnRHa
- Where
- China
- Volunteers
- 562 people
- Sponsor
- Fudan University
Healthy Infants
Efficacy of Two HMOs in Chinese Infants
This is a randomized, controlled, double-blind, intervention trial of healthy male and female term infants to evaluate the efficacy of the 2 HMOs on beneficially modulating the gut microbiota, gut maturation, gut barrier…
- Trial name
- NCT06361719
- Testing
- Experimental Group (EG), Control Group (CG)
- Where
- China
- Volunteers
- 262 people, healthy volunteers welcome
- Sponsor
- Société des Produits Nestlé (SPN)
Gastroesophageal Reflux Disease
Development of a Novel Disease-Specific Quality of Life Questionnaire for Gastroesophageal Reflux Disease (GERD) Patients in Chinese Population
A questionnaire composed of items addressing psychological, emotional and social aspects of GERD is developed for Chinese population.
- Trial name
- NCT00165022
- Where
- China
- Volunteers
- 330 people
- Sponsor
- Chinese University of Hong Kong
Hypertension
A Study in Chinese Mild to Moderate Hypertensive Patients Comparing the Efficacy of Co-Diovan With Diovan.
Valsartan, an orally active angiotensin II receptor blocker, is registered in most countries worldwide for the treatment of hypertension. In China the usual recommended starting and maintenance dose is 80 mg o.d.
- Trial name
- NCT00250562
- Testing
- valsartan plus hydrochlorothiazide
- Where
- United States
- Volunteers
- 1,171 people, healthy volunteers welcome
- Sponsor
- Novartis
Midface Volume Deficit, Midface Contour Deficiency
A Study to Evaluate the Long-term Safety and Effectiveness of Sculptra™
This is a non-interventional, multi-center, study designed to evaluate the long-term safety and effectiveness of Sculptra™ for the correction of midface volume deficit and/or midface contour deficiency in subjects of Chinese…
- Trial name
- NCT07891767
- Where
- China
- Volunteers
- 300 people
- Sponsor
- Galderma R&D
Chronic Obstructive Pulmonary Disease
Pharmacokinetics and Safety Study of PT010 and PT003 in Healthy Chinese Adult Subjects
A study to assess the pharmacokinetics and safety of two doses of PT010 and a single dose of PT003 in healthy Chinese adult subjects
- Trial name
- NCT03075267
- Testing
- PT010 (BGF MDI) 320/14.4/9.6 µg, PT010 (BGF MDI) 160/14.4/9.6 µg, PT003 (GFF MDI) 14.4/9.6 µg
- Where
- China
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- Pearl Therapeutics, Inc.
COPD, FEV1
Predictive Value of Inflammatory Biomarkers and FEV1 for COPD
This is a multi-center, prospective, cohort study. A total of 10,000 people aged 40～75 without lung disease will be recruited and followed for 3 years.
- Trial name
- PIFCOPD (NCT03532893)
- Testing
- No intervention
- Where
- 10 sites in China
- Volunteers
- 10,385 people, healthy volunteers welcome
- Sponsor
- Peking University First Hospital
Infertility
Evaluation of Efficacy and Safety of Highly Purified Urofollitropin in Chinese Females Undergoing an Assisted Reproductive Technology (ART) Program
Evaluate the efficacy and safety of of Highly Purified Urofollitropin for Injection Compared to Recombinant Human Follitropin Alfa for Injection in Chinese Females Undergoing an Assisted Reproductive Technology (ART) Program.
- Trial name
- NCT01922193
- Testing
- Highly Purified Urofollitropin, Recombinant Human Follitropin Alfa
- Where
- 11 sites in China
- Volunteers
- 263 people
- Sponsor
- Ferring Pharmaceuticals
Metabolic-dysfunction-associated Fatty Liver Disease (MAFLD)
Noninvasive Assessment of Metabolic Associated Fatty Liver Disease (MAFLD) in Chinese Population
Attenuation imaging (ATI) technology independently developed by Canon medical is a non-invasive examination technology for quantitative detection and analysis of liver steatosis.
- Trial name
- NCT04551716
- Where
- China
- Volunteers
- 448 people, healthy volunteers welcome
- Sponsor
- Chinese PLA General Hospital
Homeostasis, Metabolism and Nutrition Disorder
Energy Metabolism Profiles Over Weight-loss and Eating Responses
This is an exploratory controlled before-after study, which involves 112 participants, of whom 28 are with normal weight and 84 are overweight or obese.
- Conditions
- Homeostasis, Metabolism and Nutrition Disorder, Healthy, Obesity
- Trial name
- NCT05785221
- Testing
- General lifestyle and nutritional education, Personalized nutritional and lifestyle weight reduction intervention
- Where
- China
- Volunteers
- 117 people, healthy volunteers welcome
- Sponsor
- Chinese Academy of Sciences
Health Adult Subjects
An Early-stage Clinical Trial to Evaluate the Safety, Absorption, and Disposition of YR001 Ointment Following Topical Application on the Skin of Healthy Chinese Subjects
The goal of this clinical trial is to evaluate the safety, local tolerability, and pharmacokinetic (PK) profile of YR001 Topical Ointment in healthy Chinese participants.
- Trial name
- NCT07673458
- Testing
- PA032, Vehicle Ointment
- Where
- China
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Hangzhou Yirui Pharmaceutical Technology Co., Ltd
Gastrointestinal Disease
Proton Pump Inhibitor (PPI) Inappropriate Use and Economic Burden in Chinese Population
This is a descriptive retrospective database analysis study in using database. All patients with a physician PPI prescription will be selected to estimate the PPI inappropriate use.
- Trial name
- ECHO (NCT03118778)
- Where
- China
- Volunteers
- 90,895 people
- Sponsor
- AstraZeneca
Eye Diseases
Myopic Optic Neuropathy in Chinese High Myopia Population
This study intends to establish a registry cohort to enroll patients with high myopia to study the natural course of myopic optic neuropathy in Chinese adult population.
- Trial name
- NCT04302220
- Where
- China
- Volunteers
- 813 people, healthy volunteers welcome
- Sponsor
- Sun Yat-sen University
Major Depressive Disorder
Efficacy and Safety of Light Therapy in the Treatment of Non-seasonal Depressive Disorder in Chinese Population
Depression is a kind of mental illness with high incidence, high recurrence and high disability. But so far, treatment remission rates for depression remain low. Therefore, it is necessary to develop more new treatments.
- Trial name
- NCT05499117
- Testing
- Light terapy, pseudo-light therapy
- Where
- China
- Volunteers
- 80 people
- Sponsor
- Shanghai Mental Health Center
Schizophrenia
Bioequivalence Study of Long-Acting Paliperidone Palmitate in Patients With Schizophrenia
This multicenter, randomized, open-label, parallel-group, multiple-dose study is designed to evaluate the bioequivalence, at pharmacokinetic steady state, of a paliperidone palmitate injection manufactured by CSPC Zhongnuo…
- Trial name
- NCT07268430
- Testing
- Paliperidone Palmitate Injection(PP1M), Paliperidone Palmitate Injection(PP1M)(Reference Group)
- Where
- China
- Volunteers
- 256 people
- Sponsor
- CSPC Zhongnuo Pharmaceutical (Shijiazhuang) Co., Ltd.
COVID-19
Phase I Trial of a Recombinant SARS-CoV-2 Vaccine (Sf9 Cell)
This is a phase I, single-center, randomized, placebo-controlled, double-blind study, to evaluate safety, tolerability and immunogenicity of a recombinant SARS-CoV-2 vaccine (Sf9 cell) in Chinese healthy population aged 18 years…
- Trial name
- NCT04530656
- Testing
- Two doses of middle-dose recombinant SARS-CoV-2 vaccine (Sf9 Cell) at the schedule of day 0, 28, Two doses of high-dose recombinant SARS-CoV-2 vaccine (Sf9 Cell) at the schedule of day 0, 28, Three doses of high-dose recombinant SARS-CoV-2 vaccine (Sf9 Cell) at the schedule of day 0, 14, 28
- Where
- China
- Volunteers
- 168 people, healthy volunteers welcome
- Sponsor
- Jiangsu Province Centers for Disease Control and Prevention