Clinical trials: Child Development Disorder
Autism
T-ABA Group Based Early Intervention For Parents of Children With ASD
This study is a 10-week, randomized, parallel groups design which will evaluate the efficacy of T-ABA with combined parent training and individual child sessions versus T-ABA with individual sessions alone.
- Trial name
- T-ABA (NCT02202421)
- Testing
- Targeted Applied Behavior Analysis (T-ABA)
- Where
- United States
- Volunteers
- 21 people
- Sponsor
- The Cleveland Clinic
Autism
Aripiprazole in Children With Autism: A Pilot Study
This is a 6-week open pilot study of aripiprazole for the treatment of adolescents, aged 12 to 18 years, diagnosed with autism. Children who qualify for the study will be treated with aripiprazole for 6 weeks.
- Trial name
- NCT00208533
- Testing
- Aripiprazole
- Where
- United States
- Volunteers
- 11 people
- Sponsor
- Drexel University College of Medicine
Autism, Communication Disorders
iPad Application to Treat Prosodic Deficits in Students With Communication Disorders
The purpose of this study is to evaluate the utility of a specialized iPad application designed to treat difficulties with intonation (e.g., melody in voice) in children with autism spectrum disorders (ASD) and other…
- Trial name
- NCT01917864
- Testing
- iPad Application
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- Yale University
Autism Spectrum Disorder, Autism
A Novel Intervention for Training Auditory Attention in Adolescents With Autism Spectrum Disorder
Background: Previous research has shown that individuals with ASD often have difficulties coping with auditory stimuli in the environment.
- Trial name
- NCT03625999
- Testing
- video game training exercise
- Where
- United States
- Sponsor
- Boston University Charles River Campus
Autism
rTMS for Adults With Autistic Spectrum Disorder
rTMS over dorsolateral prefrontal cortex is effective in reducing repetitive behaviors in adults with autistic spectrum disorder rTMS over posterior superior temporal sulcus is effective in improving social ability in adults with…
- Trial name
- NCT01918787
- Testing
- repetitive TMS
- Where
- Taiwan
- Volunteers
- 30 people
- Sponsor
- Chang Gung Memorial Hospital
Growth Hormone Deficiency
A Single Dose Study to Evaluate the PK-PD Response and Safety of PHA-794428 in Children With Growth Hormone Deficiency
This will be the first clinical study of the development of PHA-794428 in a pediatric population. Since differences in PK and/or PD response may occur between adult and pediatric subjects, it is deemed appropriate to first…
- Trial name
- NCT00314938
- Testing
- PHA-794428
- Where
- 7 sites in Belgium, France and 3 more
- Volunteers
- 32 people
- Sponsor
- Pfizer
Autism Spectrum Disorder
Efficacy and Safety of Functional Neurogenesis Stimulation Therapy in Children With Autism Spectrum Disorder (ASD)
This study will test whether a noninvasive brain stimulation treatment called Functional Neurogenesis Stimulation (using the NeuroCytontron device) can safely improve core symptoms of Autism Spectrum Disorder (ASD) in children.
- Trial name
- NCT07276555
- Testing
- Functional Neurogenesis Stimulation Therapy
- Where
- 2 sites in United States, Mexico
- Volunteers
- 256 people
- Sponsor
- Neurocytonix, Inc.
Craniosynostosis
Osteogenic Profiling of Tissue From Children With Craniosynostosis
The primary objectives of this study are to procure human temporalis muscle, subcutaneous adipose (fat), and bone tissue samples from children with craniosynostosis, to grow cells from these tissues in vitro, to evaluate the…
- Trial name
- NCT00773643
- Testing
- biopsy
- Where
- 2 sites in United States
- Volunteers
- 29 people
- Sponsor
- University of Pittsburgh
Unilateral Cleft Lip and Palate, Cleft Lip
Evaluation of Facial Growth in Two Primary Protocols Used in the Surgical Treatment of Unilateral Cleft Lip and Palate Patients
The purpose of this study is to evaluate which surgical protocol for treating Unilateral Cleft Lip and Palate (UCLP), a single or two stage repair ( with hard palate late closure) will have less impact in mid facial growth.
- Conditions
- Unilateral Cleft Lip and Palate, Cleft Lip, Cleft Palate, Developmental Disabilities
- Trial name
- NCT02329509
- Testing
- two stage palate surgical repair, One stage Palate Surgical repair
- Volunteers
- 64 people
- Sponsor
- Professor Fernando Figueira Integral Medicine Institute
Autistic Disorder
Field Test of Motivity.Net Software for Data Collection During Behavioral Interventions
This is a study funded by a Phase II SBIR to build and test the feasibility of a new software prototype for delivering evidence-based behavioral therapy treatment for autism.
- Trial name
- NCT03919721
- Testing
- Applied Behavioral Analysis
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- Experiad LLC
Autism, Autism Spectrum Disorder
Word Learning From Parentese in Autistic Children
The overall objective of this research is to determine whether parentese delivered in the video format (Aim 1) and in live interaction (Aim 2) facilitates novel word learning in autistic children and to investigate if there are…
- Conditions
- Autism, Autism Spectrum Disorder, Neurodevelopmental Disorders
- Trial name
- NCT06649916
- Testing
- Parentese Speech, Adult Registered Speech
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- The University of Texas at Dallas
Autism Spectrum Disorder
Cognitively Enhanced Tai Chi for Executive Function in Children With Autism Spectrum Disorder
This study compares three exercise courses for children aged 8-11 years with autism spectrum disorder: Tai Chi with added cognitive challenges, standard Tai Chi, and general exercise.
- Trial name
- NCT07322952
- Testing
- Cognitively Enhanced Tai Chi, Standard Tai Chi, General Exercise
- Where
- China
- Volunteers
- 158 people
- Sponsor
- Jinan University Guangzhou
Autism Spectrum Disorder
Feasibility and Safety of a Virtual-Reality Based Job Interview Training Tool in Teenagers With High-Functioning Autism
The current project involves the application of a VR job training software. We propose to use an interactive VR job interview practice system, Virtual Reality Job Interview Training (VR-JIT), in youths with ASD at the highschool…
- Trial name
- NCT04773548
- Testing
- VR-JIT
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Kessler Foundation
Autism Disorder
Triadic Interactions of Families With Autism and Oxytocin
The study will investigate the effects of an intranasal administration of oxytocin (OT) to parents of children with autism spectrum disorders (ASD) on the quality of mother-father-child interactions.
- Trial name
- TAO (NCT01912378)
- Testing
- Oxytocin
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Autism Spectrum Disorder
Efficacy and Mechanism of rTMS in Children With ASD: an Open-label Clinical Trial
This study is a 6-week open-label clinical trial involving 20 children aged 6-10 years with autism spectrum disorder. During the study, subjects received repeated transcranial magnetic stimulation（rTMS）intervention at the left…
- Trial name
- NCT05238298
- Testing
- repetitive Transcranial Magnetic Stimulation
- Where
- China
- Volunteers
- 20 people
- Sponsor
- Xinhua Hospital, Shanghai Jiao Tong University School of Medicine
Toe Walking Behaviors, Backward Walking
Backward Walking Effects on Toe Walking in a Child With ASD: Single-Case Study
This study tested the hypothesis that backward walking exercises can reduce Toe Walking Behaviors (TWB) in children with ASD and emphasized the importance of pedobarographic measurements for quantitative TWB assessment.
- Trial name
- NCT07078214
- Testing
- Foot Sole Surface Area Measurements, Walking Exercise Program and Implementation Process
- Where
- Turkey (Türkiye)
- Volunteers
- 1 people
- Sponsor
- Giresun University
Attention Deficit Hyperactivity Disorder
Methylphenidate Study in Young Children With Developmental Disorders
The purpose of this study is to determine if methylphenidate (a common brand name is Ritalin), a medicine used for treating older children with Attention Deficit and Hyperactivity Disorder (ADHD), is also safe and helpful for…
- Trial name
- NCT00517504
- Testing
- Methylphenidate
- Volunteers
- 48 people
- Sponsor
- University of Arizona
Autism Spectrum Disorder
Effects of Low Frequency Whole Body Vibrations on Motor Skills and Sensory Integration in Children With Autism
This randomized controlled trial aims to evaluate the efficacy of low-frequency Whole Body Vibration therapy on motor skills and sensory integration in children aged 5-9 years diagnosed with mild to moderate ASD.
- Trial name
- NCT07757035
- Testing
- whole body vibration, Routine physical therapy
- Where
- Pakistan
- Volunteers
- 36 people
- Sponsor
- Riphah International University
Global Developmental Delay
Design and Implementation of a Carer Aromatherapy Training (CAT) Program for Children With Global Developmental Delay in Hong Kong: A Mixed Qualitative Study Using the COM-B Framework
This project aims to design and implement a Carer Aromatherapy Training (CAT) program, guided by the Capability, Opportunity, Motivation and Behaviour (COM-B) model, to empower carers with safe and effective aromatherapy…
- Trial name
- CAT programme (NCT07800689)
- Testing
- Carer Aromatherapy Training (CAT) program and home massage with massage oil with the mixture of Petitgrain Mandarin (Citrus reticulate) essential oil and fractionated coconut oil
- Where
- Hong Kong
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Hong Kong Metropolitan University
Scoliosis, Kyphosis
Postoperative and Chronic Pain Genetic Spine and Pectus Surgery Study
This will be an open label, prospective study to determine the association between specific genotypes, epigenetics and behavioral factors, with the phenotypes, defined by pain perception, postoperative pain, analgesic and side…
- Conditions
- Scoliosis, Kyphosis, Kyphoscoliosis, Pectus Excavatum
- Trial name
- NCT02998138
- Where
- 5 sites in United States
- Volunteers
- 880 people
- Sponsor
- Children's Hospital Medical Center, Cincinnati