Clinical trials: Child Development
Dyslexia, Developmental
Neural Mechanisms of Successful Intervention in Children With Dyslexia
Dyslexia, an impairment in accurate or fluent word recognition, is the most common learning disability affecting roughly ten percent of children.
- Trial name
- NCT04323488
- Testing
- Lindamood-Bell Seeing Stars
- Where
- United States
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Stanford University
Autism, Asperger's Syndrome
Cognitive Behavioral Therapy for Anxiety Disorders in Adolescents With Autism
Due to the considerable prevalence of anxiety in youth with autism spectrum disorders, this study seeks to establish the efficacy of a modified cognitive behavioral therapy protocol in 50 adolescents versus other available…
- Conditions
- Autism, Asperger's Syndrome, Pervasive Developmental Disorder Not Otherwise Specified, Generalized Anxiety Disorder
- Trial name
- NCT01563003
- Testing
- Cognitive Behavioral Therapy, Treatment as usual
- Where
- United States
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- University of South Florida
Developmental Language Disorder, Specific Language Impairment
Retrieval-Based Word Learning in Developmental Language Disorder During Book Reading
Children with developmental language disorder (DLD; also referred to as specific language impairment) experience a significant deficit in language ability that is longstanding and harmful to the children's academic, social, and…
- Conditions
- Developmental Language Disorder, Specific Language Impairment, Language Development
- Trial name
- NCT06026124
- Testing
- Retrieval-based word learning: Repeated Spaced Retrieval condition, Retrieval-based word learning: Repeated Study condition
- Where
- 2 sites in United States
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- Purdue University
Developmental Language Disorder and Language Impairment, Specific Language Impairment
Retrieval-Based Word Learning in Developmental Language Disorder During Book Reading II
Children with developmental language disorder (DLD; also referred to as specific language impairment) experience a significant deficit in language ability that is longstanding and harmful to the children's academic, social, and…
- Conditions
- Developmental Language Disorder and Language Impairment, Specific Language Impairment, Language Development
- Trial name
- NCT07048392
- Testing
- Retrieval-based word learning: Repeated Spaced Retrieval condition, Retrieval-based word learning: Repeated Study condition
- Where
- United States
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Purdue University
Autism Spectrum Disorder, Healthy
Effects of Drugs on Responses to Brain and Emotional Processes
To study the effects of a psychostimulant on responses to affective touch in individuals with a range of autistic traits
- Trial name
- MAT (NCT04053036)
- Testing
- MDMA
- Where
- United States
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- University of Chicago
Autism Spectrum Disorder, Typical Development
Improving Social Interaction for Adolescents With Autism During the Transition to Adulthood
This study compares the efficacy of two intervention strategies for improving social outcomes for autistic adolescents and young adults when interacting with unfamiliar non-autistic peers.
- Trial name
- NCT03785327
- Testing
- tDCS, Autism Training
- Where
- United States
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- The University of Texas at Dallas
Autism Spectrum Disorder
CPI Training for Parents of Children With ASD
The purpose of this 24-week study is to determine whether the "Parent-based Crisis Prevention Institute (CPI) physical management training program" (i.e., P-CPI) is effective in increasing self-efficacy in parents of children…
- Trial name
- NCT03537261
- Testing
- Parent-based Crisis Prevention Institute (CPI) physical management training program (P-CPI)
- Where
- United States
- Volunteers
- 81 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Chronic Toxic Stress, Developmental/ Behavioral Regression in Young Children
(YMP) Young Moms Program
Young Moms Program (YMP) is designed to address systemic barriers to the health and stability of young moms and their children such as the lack of coordination of service delivery or logistical barriers within the health system.
- Trial name
- YMP (NCT05082857)
- Testing
- "traditional" Parents as Teachers (PAT), "hybrid" PAT model
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Wake Forest University Health Sciences
Early Child Development
Testing Means to Scale Early Childhood Development Interventions in Rural Kenya
This study aims to experimentally test the effectiveness and cost-effectiveness of competing models of delivery of an Early Childhood Development (ECD) intervention in rural Kenya to determine how to maximize their reach to…
- Trial name
- NCT03548558
- Testing
- Group sessions, Group+Home sessions, Booster sessions
- Where
- United States
- Volunteers
- 1,152 people, healthy volunteers welcome
- Sponsor
- University of Southern California
Autism Spectrum Disorder
A Feasibility Study of N-acetylcysteine for Self-injurious Behavior in Children With Autism Spectrum Disorder
The purpose of this study is to demonstrate the feasibility of a 9-week, randomized trial of N-acetylcysteine (NAC) compared to placebo in 14 children (age 5 to 12 years) with Autism Spectrum Disorder (ASD) and a moderate level…
- Trial name
- NAC (NCT03008889)
- Testing
- N-acetylcysteine
- Where
- United States
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Emory University
Autism Spectrum Disorder, Gastrointestinal Symptoms
Combination Probiotic: BB-12 With LGG (Different Doses) in Treating Children With Autism Spectrum Disorder
This protocol is a blinded randomized controlled study of the effects of BB-12 with LGG at different doses in 70 healthy children with autism spectrum disorders at lower and higher doses over an 56-day period and a 28- day…
- Trial name
- NCT03514784
- Testing
- BB-12 with LGG (Higher Dose), BB-12 with LGG (Lower Dose)
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- The University of Texas Health Science Center, Houston
Hospitalism in Children, Post Traumatic Stress Disorder
Pilot Testing of an Equity Focused and Trauma-informed Communication Intervention During Family-centered Rounds
Development and pilot testing of a clinician coaching communication intervention to improve communication between medical teams and caregivers (parents, family members) of children in the hospital.
- Trial name
- EFTI (NCT05618652)
- Testing
- Equity Focused and Trauma-Informed Communication Intervention
- Where
- United States
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- Duke University
Autistic Disorder, Autism Spectrum Disorder
A Study to Investigate the Safety, Tolerability, Pharmacokinetics, Pharmacodynamics and Food Effect of RO6953958 in Healthy Participants
This study will evaluate the safety, tolerability, pharmacokinetics (PK) and pharmacodynamics (PD) of single- and multiple-ascending doses (SAD (Part 1) and MAD (Part 2)) and food effect (FE) of RO6953958 following oral…
- Conditions
- Autistic Disorder, Autism Spectrum Disorder, Child Development Disorders, Pervasive, Mental Disorders
- Trial name
- NCT04475848
- Testing
- RO6953958, Midazolam
- Where
- United Kingdom
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- Hoffmann-La Roche
Asthma in Children
BREATHE-Peds Pilot- II III Trial and Post Trial
The overall aims of this study are to develop and pilot test BRief intervention to Evaluate Asthma THErapy (BREATHE)-Peds, a dyadic shared decision-making intervention, to improve asthma by supporting self-management among racial…
- Trial name
- NCT05832437
- Testing
- BREATHE-Peds Intervention, Control Intervention
- Where
- 3 sites in United States
- Volunteers
- 67 people, healthy volunteers welcome
- Sponsor
- Columbia University
Child Development
Added Sugar Intake and Brain Structure and Function
The purpose of this study is to learn if there is a relationship between added sugar intake during pregnancy, infancy, and toddlerhood and the brain's structure and function at 5-6 years old.
- Trial name
- GAINS BRAINS (NCT06640829)
- Where
- United States
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- University of Kansas Medical Center
Autism Spectrum Disorders, Autism
Psychotherapy for Anxiety in Children With Autism Spectrum Disorder
Anxiety disorders affect 40 to 50% of children with autism spectrum disorders (ASD), contributing to substantial distress and impairment.
- Conditions
- Autism Spectrum Disorders, Autism, Asperger's Syndrome, Pervasive Developmental Disability - Not Otherwise Specified
- Trial name
- TAASD (NCT02028247)
- Testing
- Personalized Cognitive-behavioral therapy, Standard Practice Cognitive-behavioral therapy, Treatment as Usual
- Where
- United States
- Volunteers
- 214 people, healthy volunteers welcome
- Sponsor
- University of South Florida
Autism Spectrum Disorder
Effectiveness of a 6-week Hippotherapy Program in Children With Autism Spectrum Disorder
The prevalence of autism spectrum disorders (ASD) has increased dramatically in the last decade. The increasing occurrence of ASD creates an imperative need to test the effectiveness and efficacy mechanisms of appropriate…
- Trial name
- NCT04772898
- Testing
- Hippotherapy
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Creighton University
Autism or Autistic Traits, Mental Health Disorder
The Effects of Executive Functions and Social Cognition on Mental Health
The objective of this study is to analyze the effects of executive functions (EFs) and social-cognitive abilities on the associations between autistic traits and mental health indicators (depression, anxiety, and stress).
- Conditions
- Autism or Autistic Traits, Mental Health Disorder, Executive Dysfunction, Social Cognition
- Trial name
- NCT06213194
- Testing
- MindZone
- Where
- Turkey (Türkiye)
- Volunteers
- 178 people, healthy volunteers welcome
- Sponsor
- Ibn Haldun University
Autism Spectrum Disorder, Apraxia of Speech
Video Assisted Speech Technology to Enhance Motor Planning for Speech
Nearly 3.5 million Americans are diagnosed with Autistic Spectrum Disorder (ASD), a communication disorder that causes skill limitations in the areas of language acquisition, sensory integration, and behavior.
- Trial name
- VAST (NCT04764539)
- Testing
- Video Assisted Speech Therapy (VAST)
- Where
- United States
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- iTherapy, LLC
Behavioral Insomnia of Childhood
Development of Sleep Intervention for Parent and Child
This study aims to develop and test the intervention program to help manage parental thoughts in parents with child sleep problems.
- Trial name
- NCT05806450
- Testing
- Intervention, Active control condition
- Where
- South Korea
- Volunteers
- 190 people, healthy volunteers welcome
- Sponsor
- Sungshin Women's University