Clinical trials: Child
HIV Infections
A Study of Dideoxycytidine Plus Zidovudine (AZT) in HIV-Infected Children Who Have Taken AZT
PRIMARY: To determine safety, tolerance, and pharmacokinetics of zidovudine (AZT) and zalcitabine (dideoxycytidine; ddC) when given in combination in clinically stable AZT-treated children.
- Trial name
- NCT00001032
- Testing
- Zidovudine, Zalcitabine
- Where
- 47 sites in United States, Puerto Rico
- Volunteers
- 180 people
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Molar Incisor Hypomineralization, Oral Health
Prevalence, Etiology and Effects on Oral Health and Life Quality of Molar Incisor Hypomineralization
Molar incisor hypomineralization (MIH) can lead to many clinical conditions and affect oral health-related quality of life (OHRQoL).
- Conditions
- Molar Incisor Hypomineralization, Oral Health, Child, Only, Pediatric ALL
- Trial name
- NCT05779332
- Testing
- survey application
- Where
- Turkey (Türkiye)
- Volunteers
- 655 people, healthy volunteers welcome
- Sponsor
- Recep Tayyip Erdogan University Training and Research Hospital
Picky Eating
PEaters Choice™: Nutrition Intervention Module for Picky Eaters
Picky eaters (PE) are defined as individuals with a lack of diversity in food intake and fear of trying new foods which generally leads to malnutrition. Globally, between 20% to 55% of children worldwide are being reported as PE.
- Trial name
- PEaters (NCT05445193)
- Testing
- PEaters Choice Module
- Where
- Malaysia
- Volunteers
- 154 people
- Sponsor
- National University of Malaysia
Asthma
Childhood Asthma Mentoring Program for Parents
There are 7.1 million children with asthma. Asthma is the cause of 10.5 million missed days of school, 7.5 million outpatient visits, 640,000 ED visits, and 157,000 hospitalization visits in 2008.
- Trial name
- CAMPP (NCT02747706)
- Testing
- Parent-to-parent mentoring
- Where
- United States
- Volunteers
- 240 people
- Sponsor
- InquisitHealth, Inc.
Anxiety
Effectiveness of Play Interventions on Anxiety Among Hospitalized Children
The study evaluates the effectiveness of play interventions on anxiety among hospitalized children in selected hospital of Yamuna Nagar, Haryana. Quasi experimental approach was adopted.
- Trial name
- NCT03222063
- Testing
- Play interventions
- Volunteers
- 60 people
- Sponsor
- Maharishi Markendeswar University (Deemed to be University)
Food Allergy
Use of Hypoallergenic (H.A.) Cereals in Children With Diagnosed Allergy to Wheat
The investigators plan to launch a Specific Oral Tolerance Induction (SOTI) pilot study in order to assess the efficacy and the safety of hypoallergenic (H.A.) wheat cereals, for children with allergy to wheat.
- Trial name
- NCT01332084
- Testing
- HA wheat cereals
- Where
- 2 sites in Switzerland
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- Société des Produits Nestlé (SPN)
Leukemia
Diagnostic Study of Gene Alterations in Children Who Have Been Treated for Relapsed Acute Lymphocytic Leukemia
RATIONALE: Diagnostic procedures, such as genetic testing, may improve the ability to detect acute lymphocytic leukemia and determine the extent of disease.
- Trial name
- NCT00003933
- Testing
- laboratory biomarker analysis
- Where
- 41 sites in United States, Australia and 1 more
- Sponsor
- Children's Oncology Group
Systemic Lupus Erthematosus (SLE)
Team-based Implementation of Hypertension Management in Childhood Lupus
The goal of this study is to compare the effectiveness of widely used implementation strategies to promote adherence to guideline-concordant evidence-based practices for monitoring and controlling blood pressure in patients with…
- Trial name
- ABOUT TIME (NCT07792733)
- Testing
- Health Navigator Engagement, Team Charter with Performance Monitoring, Pre-visit worksheet
- Volunteers
- 1,200 people
- Sponsor
- Boston Children's Hospital
Urinary Tract Infections in Children
7-day Compared With 10-day Antibiotic Treatment for Febrile Urinary Tract Infections in Children
The investigators aim to assess the effectiveness of a 7-day compared with a 10-day course of antibiotic treatment for febrile urinary tract infections (UTIs) in children.
- Trial name
- NCT03221504
- Testing
- Longer therapy duration, Shorter therapy duration
- Where
- 2 sites in Poland
- Volunteers
- 221 people
- Sponsor
- Medical University of Warsaw
Food Allergy in Children
Friends, Family & Food: Food Allergy App for Youth - II
Objective: This Phase II STTR grant incorporated user feedback collected in an earlier development project to build interactive, web-based software that helps children with food allergies learn about their condition and gain…
- Trial name
- F3A-App (NCT05111938)
- Testing
- Friends, Family, and Food App (F3A-App)
- Volunteers
- 80 people
- Sponsor
- Rhode Island Hospital
Recurrent Respiratory Papillomatosis (RRP), Juvenile-onset Recurrent Respiratory Papillomatosis
Zopapogene Imadenovec for the Treatment of Recurrent Respiratory Papillomatosis in Children
Recurrent respiratory papillomatosis (RRP) is a rare disease in which wart-like growths caused by human papillomavirus (HPV) types 6 or 11 form in the airway.
- Conditions
- Recurrent Respiratory Papillomatosis (RRP), Juvenile-onset Recurrent Respiratory Papillomatosis, Papillomavirus Infections
- Trial name
- NCT07901738
- Testing
- Zopapogene imadenovec-drba
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Precigen, Inc
Child Obesity
Mixed Methods Feasibility Study of an App for Childhood Obesity Prevention and Management
This evaluation evaluated Health Education England's NoObesity digital health app's usability and acceptability to undertake activities improving families' diet, physical activity and weight.
- Trial name
- NCT05261555
- Testing
- NoObesity app
- Where
- United Kingdom
- Volunteers
- 231 people, healthy volunteers welcome
- Sponsor
- University of Plymouth
Caries
Post-operative Pain and Child Behavior of Hall Technique Versus SDF in the Management of Carious Primary Molars: RCT
PICO question: Papulation: children suffering from caries Intervention: Silver Diamine Fluoride Comparison: Hall technique Outcome: Primary Outcome: Intraoperative and postoperative pain Measurement device: Face pain scale…
- Trial name
- NCT04794426
- Testing
- Silver diamine fluoride, Hall Technique
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Noura Mohamed Alhosaini
CHILDREN BORN VERY PRETERM AT SCHOOL-AGE
QUALITY OF LIFE OF CHILDREN BORN VERY PRETERM AT SCHOOL-AGE
AIMS The aims were 1) to describe the quality of life (QoL) of a cohort of children born very preterm (<28 weeks of gestation) aged 7 to 9 years; 2) to compare children's QoL to the QoL reported by a French general population of…
- Trial name
- NCT01675726
- Testing
- questionary on quality of life
- Where
- France
- Volunteers
- 350 people
- Sponsor
- Assistance Publique Hopitaux De Marseille
Flexible Flatfoot
Early Warning and Intervention Mechanism of Foot Health Risk in Children and Adolescents
This clinical study was a prospective intervention study. The growth and development parameters and kinematic parameters of 120 children were planned to be collected for an observational study, and then the sensors were used to…
- Trial name
- NCT06581978
- Testing
- Whole-Body Vibration Intervention, Exercise Intervention Group
- Where
- China
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Nanfang Hospital, Southern Medical University
Anemia, Intrauterine Growth Retardation
Impact of Pre-pregnancy Micronutrient Supplementation on Maternal and Child Outcomes
The study evaluates the efficacy of providing weekly iron-folate (IFA) supplements or Multiple Micronutrient (MM) supplements before pregnancy in increasing birth weight and duration of gestation as well as maternal and infant…
- Conditions
- Anemia, Intrauterine Growth Retardation, Preterm Delivery, Iron Deficiency
- Trial name
- NCT01665378
- Testing
- Multiple Micronutrient, Iron and Folic Acid, Folic Acid
- Where
- Vietnam
- Volunteers
- 5,011 people, healthy volunteers welcome
- Sponsor
- Emory University
Dental Caries in Children
Partial or Complete Excavation of Deep Caries in Primary Molars
Background: The traditional approach of carious lesions with risk for progression has has been to excavate all infected and demineralised tissue before placement of the restoration.
- Trial name
- PBRN (NCT04614285)
- Testing
- Partial excavation
- Where
- Sweden
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Karolinska Institutet
Constipation
Diurnal Variation in Rectal Diameter
The purpose of the study is to determine the diurnal variation of rectal diameter in healthy and constipated children using transabdominal ultrasound.
- Trial name
- NCT01695915
- Testing
- Transabdominal ultrasound
- Where
- Denmark
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Line Modin
Gastroparesis, Functional Dyspepsia
Controlled Trial of Gastric Electrical Stimulation in Children
This study evaluates whether gastric electrical stimulation (GES) improves symptoms in children with severe nausea and vomiting that have not responded to standard treatments.
- Conditions
- Gastroparesis, Functional Dyspepsia, Vomiting Syndrome
- Trial name
- NCT07474415
- Testing
- Temporary Gastric Electrical Stimulation
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Nationwide Children's Hospital
Cough
Efficacy & Tolerability of a Specific Plantain,Thyme and Honey Cough Syrup vs Placebo in Child Cough Due to Common Cold
Cough is a life saving reflex, therefore it is important, especially in pediatrics, to calm cough spells without sedating the reflex.
- Trial name
- NCT02486835
- Testing
- Cough syrup for adults and children
- Where
- 4 sites in Israel
- Volunteers
- 150 people
- Sponsor
- Clalit Health Services