Clinical trials: Chest Wall Disorders
Respiratory Failure, Neuromuscular Disease
Ventilator Monitoring in Early Exacerbation Detection
The aim of this study is to determine whether respiratory disease exacerbations (a sudden worsening of symptoms) can be predicted by variables that are monitored by non-invasive ventilators (small machines that assist breathing)…
- Conditions
- Respiratory Failure, Neuromuscular Disease, Chest Wall Disorder, Chronic Obstructive Pulmonary Disease
- Trial name
- NCT01644162
- Testing
- iVAPS ventilation
- Where
- United Kingdom
- Volunteers
- 30 people
- Sponsor
- ResMed
Chest Wall Disorder, Neuromuscular Disease
AutoVPAP Versus VPAP; Assessment of Sleep and Ventilation
The aim of the study is to compare the effects of a modified form (AutoVPAP) of the VPAP non-invasive ventilator versus standard VPAP ventilation on sleep quality and breathing during sleep in stable patients with nocturnal…
- Trial name
- NCT00252252
- Testing
- VPAP non-invasive ventilator, AutoVPAP non-invasive ventilator
- Where
- United Kingdom
- Volunteers
- 20 people
- Sponsor
- ResMed
Bronchial Asthma, Asthma
HFCWO in Hospitalized Asthmatic Children
To determine whether or not high frequency chest wall oscillation (in the form of the VestTM) is superior to regular asthma therapy in the management of children hospitalized with moderate to severe asthma.
- Conditions
- Bronchial Asthma, Asthma, Status Asthmaticus
- Trial name
- NCT00722020
- Testing
- VEST
- Where
- 2 sites in United States
- Volunteers
- 43 people
- Sponsor
- Hill-Rom
Cystic Fibrosis, Bronchiectasis
Effect of High Frequency Chest Wall Oscillation Vests on Spirometry Measurements
The impact of high-frequency chest wall oscillation therapy on spirometry values (Forced Expiratory Volume, Forced Vital Capacity, Peak Expiratory Flow, Forced Expiratory Flow and Tidal Volume is investigated during use of…
- Trial name
- NCT03534986
- Testing
- International Biophysics AffloVest, Hill-Rom The Vest, Respirtech inCourage
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- International Biophysics Corporation
Chronic Obstructive Pulmonary Disease, Dyspnea
A Wearable In-phase Chest Wall Vibration Device for Relief of Dyspnoea in COPD: a First-in-human Exploratory Study
The goal of this exploratory clinical trial is to evaluate the initial clinical safety and performance of a prototype wearable chest wall vibration (CWV) device intended to relieve exertional dyspnea in adults with Chronic…
- Trial name
- ResWave (NCT06432920)
- Testing
- ResWave
- Where
- Ireland
- Volunteers
- 20 people
- Sponsor
- Elevre Medical Ltd.
Breast Cancer
Phase 1/2 Study of ThermoDox With Approved Hyperthermia in Treatment of Breast Cancer Recurrence at the Chest Wall
This is a research study to evaluate the effects of ThermoDox in combination with therapeutic heating of the chest wall in the treatment of recurrent regional breast cancer.
- Trial name
- DIGNITY (NCT00826085)
- Testing
- ThermoDox in combination with Microwave Hyperthermia (heat)
- Where
- 6 sites in United States
- Volunteers
- 17 people
- Sponsor
- Imunon
Nocturnal Hypoventilation, Neuromuscular Disease
Autotitrating Versus Standard Non-invasive Ventilation (NIV) in Newly Diagnosed Patients
The aim of the study is to compare the efficacy and tolerance of autotitrating non-invasive ventilation (NIV) versus standard NIV in patients with newly diagnosed nocturnal hypoventilation who have never experienced nocturnal…
- Conditions
- Nocturnal Hypoventilation, Neuromuscular Disease, Chest Wall Disorder
- Trial name
- NCT00901485
- Testing
- AutoVPAP, VPAPIIIST-A
- Where
- United Kingdom
- Volunteers
- 23 people
- Sponsor
- ResMed
Bronchiectasis
Clinical Effectiveness Of High Frequency Chest Wall Oscillation (HFCWO) In A Bronchiectasis Population
The primary objective is to compare the patient's baseline QoL prior to HFCWO use against the patient's QoL at various study timepoints over a one-year period of HFCWO use.
- Trial name
- HFCWO (NCT04271969)
- Testing
- SmartVest Airway Clearance System
- Where
- 4 sites in United States
- Volunteers
- 25 people
- Sponsor
- Electromed, Inc.
Respiratory Failure, Neuromuscular Disease
Autotitrating Versus Standard Non-invasive Ventilation (NIV) in Acute Exacerbation of Respiratory Failure
The aim of the study is to compare the efficacy and tolerance of autotitrating non-invasive ventilation (NIV) versus standard NIV in patients admitted to hospital with acute exacerbation of chronic respiratory failure.
- Conditions
- Respiratory Failure, Neuromuscular Disease, Chest Wall Disorder, Chronic Obstructive Pulmonary Disease
- Trial name
- NCT01174316
- Testing
- AutoVPAP™, VPAPIIIST-A™
- Where
- United Kingdom
- Sponsor
- ResMed
Cystic Fibrosis, Bronchiectasis
Effect of HFCWO Vests on Spirometry Measurements
The impact of high-frequency chest wall oscillation therapy on spirometry values (Forced Expiratory Volume, Forced Vital Capacity, Peak Expiratory Flow, Forced Expiratory Flow and Tidal Volume is investigated during use of…
- Trial name
- NCT03628456
- Testing
- International Biophysics AffloVest, Hill-Rom Monarch
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- International Biophysics Corporation
Bronchiectasis, Bronchiectasis With Acute Exacerbation
A Pilot Study to Evaluate the Use of the Vest® System for Treatment of Bronchiectasis Patients in the Home Setting
This a 70 patient multi-site non blinded randomized control trial evaluating the use of the Vest® System for treatment of Non-Cystic Fibrosis Bronchiectasis (NCFBE) patients in the home setting.
- Trial name
- NCT04017312
- Testing
- High Frequency Chest Wall Oscillation, Oscillating Positive Expiratory Pressure (OPEP)
- Where
- 3 sites in United States
- Volunteers
- 43 people
- Sponsor
- Hill-Rom
Cerebral Palsy
Study Assessing High-Frequency Chest Wall Oscillation (HFCWO) in Preventing Pulmonary Exacerbations
To asssess efficacy of airway clearance provided by Vest therapy (HFCWO) in the reduction of respiratory exacerbations requiring hospitalization or antibiotic utilization in patients with muscle weakness and restrictive lung…
- Trial name
- NCT00739310
- Testing
- Vest Treatment (high frequency chest wall oscillation)
- Where
- United States
- Volunteers
- 29 people
- Sponsor
- Hill-Rom
Breast Cancer
A Novel Therapy for the Treatment of Chest Wall Progression of Breast Cancer
This study will assess safety and ergonomics/engineering design of a novel cancer treatment, Continuous Low Irradiance Photodynamic therapy (CLIPT).
- Trial name
- NCT01262716
- Where
- United States
- Volunteers
- 3 people
- Sponsor
- Rogers Sciences Inc.