Clinical trials: Chest Tubes
Air Leakage
Digital Chest Tube Drainage System (Thopaz+) Versus Analog in Pediatric Patients
In 2007 the Thopaz digital drainage system was launched as one of the first chest tube drainage systems to utilize a digital rather than analog device.
- Trial name
- THOPAZ (NCT05511987)
- Testing
- Madela THOPAZ Digital Device, Atrium Analog Device
- Where
- United States
- Volunteers
- 140 people
- Sponsor
- University of Oklahoma
Critical Care Medicine, Mechanical Ventilation
Evaluating the Clinical Effectiveness of "Endotracheal Tube Position Anomaly Alerting System"
The goal of this clinical trial is to determine whether the Endotracheal Tube Position Anomaly Alerting System (ETPAAS) effectively reduces the duration of endotracheal tube malposition in patients admitted to the intensive care…
- Conditions
- Critical Care Medicine, Mechanical Ventilation, Radiographic Image Interpretation, Computer-Assisted, Alarms
- Trial name
- ETPAAS-1 (NCT06857019)
- Testing
- "Endotracheal Tube Position Anomaly Alerting System"
- Where
- Taiwan
- Volunteers
- 200 people
- Sponsor
- Kaohsiung Medical University Chung-Ho Memorial Hospital
Coronary Artery Bypass Graft Surgery(CABG), Postoperative Pain Management
VR During Chest Tube Removal After CABG
The purpose of this randomized controlled clinical trial was to investigate whether virtual reality (VR) could reduce pain and anxiety during chest tube removal in adult patients who underwent coronary artery bypass graft (CABG)…
- Trial name
- VR-CABG (NCT07891299)
- Testing
- VR Shinecon G04EA Virtual Reality Headset
- Where
- Turkey (Türkiye)
- Volunteers
- 82 people
- Sponsor
- Maltepe University
Chest Pain
Pain During Chest Tube Withdrawal: Evaluation Using Pan Monitor
Pain evaluation remains a clinical problem. Pain Monitor allows pain evaluation using the measurement of skin conductance. Withdrawal of chest tube can be painful and the purpose of the study was to compare auto-evaluation of…
- Trial name
- Pain Drain (NCT02015858)
- Testing
- Chest drain withdrawal, Pain Monitor
- Where
- France
- Volunteers
- 100 people
- Sponsor
- Hopital Foch
Pneumothorax
Pneumothorax Therapy: Manual Aspiration Versus Conventional Chest Tube Drainage
The purpose of this study is to evaluate the efficacy of manual aspiration in comparison to conventional chest tube drainage in pneumothorax therapy: 1. whether manual aspiration will shorten hospital admission. 2.
- Trial name
- pneumothorax (NCT00556335)
- Testing
- manual aspiration, conventional drainage
- Where
- Netherlands
- Volunteers
- 56 people
- Sponsor
- Isala
Transcutaneous Electrical Nerve Stimulation, Procedural Pain
Effect of TENS Application After Thoracic Surgery
After thoracic surgery, a chest tube is inserted to evacuate the air and fluid formed in the pleural space and to provide hemodynamic stability.
- Trial name
- NCT05927168
- Testing
- TENS
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Cukurova University
Chest Tube Removal
Effect of Warm Footbath Combined With Relaxation Exercise on Pain and Anxiety During Chest Tube Removal After Cardiac Surgery
Chest tube removal is a widely used surgical procedure, particularly in the post-cardiac surgery period, to maintain cardiopulmonary stability, provide mediastinal drainage, and prevent potential complications.
- Trial name
- NCT07585240
- Testing
- Relaxation Exercises, Warm Water Foot Bath
- Volunteers
- 60 people
- Sponsor
- Igdir University
Lung Neoplasms, Lung Surgery
Chest dRain rEmoval intrAoperatively afTer thoracOscopic Wedge Resection
Chest drain is used routinely after lung surgery. Despite preliminary studies demonstrate the feasibility and safety of intraoperative chest drain removal, these are either retrospective or mainly concerning benign disease.
- Conditions
- Lung Neoplasms, Lung Surgery, Enhanced Recovery After Surgery, Fast-track Surgery
- Trial name
- CREATOR (NCT05358158)
- Testing
- Intraoperative air leak test, Intraoperative chest drain removal, Standard chest drain placement
- Where
- 2 sites in Denmark
- Volunteers
- 94 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Lung Neoplasms, Lung Cancer
Effect of Muscle and Skin Fixation of Thoracic Drainage Tube on Postoperative Pain
Lung cancer is the leading cause of cancer-related death worldwide. Thoracoscopic pulmonary resection is a prevalent management for early stage of lung cancer.
- Conditions
- Lung Neoplasms, Lung Cancer, Pulmonary Neoplasm, Postoperative Pain
- Trial name
- NCT05202249
- Testing
- muscle layer fixation of thoracic drainage tube
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Daping Hospital and the Research Institute of Surgery of the Third Military Medical University
Cervical Cancer, Fallopian Tube Cancer
Immunotoxin Therapy in Treating Patients With Advanced Solid Tumors
RATIONALE: Immunotoxins can locate tumor cells and kill them without harming normal cells. Immunotoxin therapy may be effective in treating advanced solid tumors.
- Conditions
- Cervical Cancer, Fallopian Tube Cancer, Head and Neck Cancer, Lung Cancer
- Trial name
- NCT00066651
- Testing
- SS1(dsFv)-PE38 immunotoxin
- Where
- 2 sites in United States
- Sponsor
- National Cancer Institute (NCI)
Neoplasms
First-Time-in-Human Study of GSK4381562 in Participants With Advanced Solid Tumors
This is a first time in-human (FTIH) study designed to investigate the safety, tolerability, pharmacokinetics (PK), and immunogenicity of remzistotug in participants with select loco-regionally recurrent solid tumors or…
- Trial name
- NCT05277051
- Testing
- Remzistotug, Dostarlimab, Belrestotug
- Where
- 26 sites in United States, Australia and 7 more
- Volunteers
- 152 people
- Sponsor
- GlaxoSmithKline
Autologous Blood Patch Therapy
ABPT in Secondary Pneumothorax With Persistent Airleak Study
This is a prospective clinical trial with each patient serving as his/her own control. Patients will be recruited in three different Hong Kong hospital.
- Trial name
- ABPT (NCT04132687)
- Testing
- autologous blood patch therapy
- Where
- 2 sites in Hong Kong
- Volunteers
- 35 people
- Sponsor
- Chinese University of Hong Kong
Chest Tube Removal
Cold Application on Pain During Chest Tube Removal
Abstract Objectives: Use of analgesics is the most common method to alleviate the pain induced by chest tube removal (CTR), but patient response to medication can vary and may not be achieved complete relaxation.
- Trial name
- NCT03307239
- Testing
- cold application, tap water packs application
- Volunteers
- 60 people
- Sponsor
- Chiayi Christian Hospital
Thoracic Surgery
Criteria for Choice of Right Double Lumen Tube (DLT)
There are specific guidelines for choice of Lt DLT size in correlation to patient's height and tracheal diameter on chest X-ray/CT scan. Accordingly to these criteria the RT DLT size is determined.
- Trial name
- NCT00793936
- Volunteers
- 40 people
- Sponsor
- Assaf-Harofeh Medical Center
Cancer
Intrapleural BG00001 in Treating Patients With Malignant Pleural Mesothelioma or Malignant Pleural Effusions
RATIONALE: Using BG00001 to insert the gene for interferon-beta into a person's pleural cavity may improve the body's ability to fight cancer.
- Trial name
- NCT00066404
- Testing
- recombinant adenovirus-hIFN-beta
- Where
- United States
- Sponsor
- Abramson Cancer Center at Penn Medicine
The Efficacy of Percutaneous Catheter vs. Open Chest Tube, Traumatic Hemothorax
Multi-center:The Small (14F) Percutaneous Catheter vs. Large (28-40F) Open Chest Tube for Traumatic Hemothorax (P-CAT)
After sustaining severe trauma to the chest, patients will often bleed into the chest cavity (pleural space) which is called hemothorax or they may also experience air leakage within the chest cavity in combination with the…
- Trial name
- P-CAT (NCT03546764)
- Testing
- Percutaneous catheter
- Where
- 4 sites in United States
- Volunteers
- 61 people, healthy volunteers welcome
- Sponsor
- University of Arizona
Persistent Air Leaks
Thopaz for PALs Evaluation
Persistent air leaks (PALs) are a common postoperative complication resulting from tears in the visceral pleura or peripheral lung resections.
- Trial name
- NCT07105436
- Testing
- Persistent air leak quantification
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Kai Swenson
One-Lung Ventilation, Thoracic Surgery
Left Double Lumen Tube Selection
The aim of this study was to determine the accuracy and practicality of ultrasound in the selection of double lumen tube and whether the complications that may occur intraoperatively and postoperatively can be reduced.
- Trial name
- NCT06457763
- Testing
- Ultrasound
- Where
- Turkey (Türkiye)
- Volunteers
- 74 people, healthy volunteers welcome
- Sponsor
- Marmara University
Congenital Heart Disease (CHD), Chest Tube Removal
The Effect of Music and Musical Mobile Interventions on Pain and Physiological Parameters
Chest tube removal in infants undergoing surgery for congenital heart disease is an invasive procedure associated with significant pain and physiological stress responses.
- Trial name
- Music Pain Inf (NCT07564882)
- Testing
- Music Group, Musical Mobile Group
- Where
- Turkey (Türkiye)
- Volunteers
- 54 people
- Sponsor
- Baskent University
Non-small Cell Lung Cancer
Suction on Post-Operative Chest Tubes
The level of suction on post-operative chest tubes after video-assisted thoracoscopic surgery (VATS) lobectomy for lung cancer has previously shown to affect duration of drainage.
- Trial name
- SPOCT (NCT02911259)
- Testing
- Suction is set to -2 cmH2O, Suction is set to -10 cmH2O
- Where
- Denmark
- Volunteers
- 230 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet