Clinical trials: Chest Trauma
Chest Trauma, High Flow Oxygenation
Management of Moderately Hypoxemic Thoracic Trauma
In France, the average incidence of thoracic trauma is 10,000 to 15,000 each year. These patients are at risk of early and late post traumatic respiratory complications as follows: pneumonia, Acute Respiratory Distress Syndrome…
- Trial name
- TrOMaTho (NCT03997630)
- Testing
- High flow Oxygenation, Standard oxygen
- Where
- 18 sites in France
- Volunteers
- 770 people
- Sponsor
- University Hospital, Brest
Pseudomonas Infection, Cystic Fibrosis
Role of Toxins in Lung Infections Caused by Pseudomonas Aeruginosa
Some bacteria that cause disease can produce toxic substances that may worsen the disease. Pseudomonas aeruginosa is a bacteria that can produce a variety of toxins and is of special interest for patients with cystic fibrosis and…
- Trial name
- NCT00027183
- Where
- United States
- Volunteers
- 134 people
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Perioperative Complications, Perioperative/Postoperative Complications
Perioperative Database of Chinese Elderly Patients
The investigators aim to establish a prospective database of perioperative elderly patients from multiple regions and centers. Collected data involves postoperative complications of the central nervous system, cardiovascular…
- Conditions
- Perioperative Complications, Perioperative/Postoperative Complications, Perioperative Adverse Events
- Trial name
- PDCEP (NCT04911530)
- Testing
- no intervention
- Where
- China
- Volunteers
- 10,000 people
- Sponsor
- Chinese PLA General Hospital
Multiple Trauma
Thoracic Injuries in Pediatric Polytraumatized Patients: Epidemiology, Treatment and Outcome
The present study predicts that concomitant chest injuries in polytraumatized pediatric patients are a potential source of substantial morbidity and mortality.
- Trial name
- NCT02398175
- Testing
- reanimation/intubation
- Volunteers
- 71 people
- Sponsor
- Medical University of Vienna
Rib Fractures, Trauma
Continuous Erector Spinae Plane Blocks for Rib Fractures
Rib fractures are one of the most common injuries in trauma patients. These fractures are associated with significant pain as well as decreased ability to inspire deeply or cough to clear secretions, which together lead to…
- Conditions
- Rib Fractures, Trauma, Anesthesia, Anesthesia, Local
- Trial name
- NCT04558281
- Testing
- Active ropivacaine 0.3% erector spinae plane perineural administration
- Where
- United States
- Volunteers
- 4 people
- Sponsor
- University of California, San Diego
Coronary Artery Disease, Cardiac Disease
The CAROLE (CArdiac Related Oncologic Late Effects) Study
CAROLE seeks to evaluate the relationship between chest Radiation Therapy and coronary artery disease. The purpose of CAROLE is to check the heart health of women who received breast cancer treatments in the past and protect them…
- Conditions
- Coronary Artery Disease, Cardiac Disease, Cardiac Toxicity, Radiation
- Trial name
- CAROLE (NCT03235427)
- Where
- United States
- Volunteers
- 201 people
- Sponsor
- Northwell Health
Spinal Cord Injuries
Extracorporeal Shockwave Therapy (ESWT) to Improve Function in Chronic ASIA-A Patients
The global prevalence of spinal cord injury is estimated between 236 to 4187/Million. A spontaneous recovery of the sense-motoric function is decreasing with the time after injury and is only seen sporadically after 1 to 2 years.
- Trial name
- NCT03399968
- Testing
- ESWT
- Where
- 2 sites in Austria
- Volunteers
- 25 people
- Sponsor
- AUVA Trauma Center Meidling
Thoracic Surgery, Obesity
Association Between Body Roundness Index and Wound Healing
Background Obesity is a significant risk factor for adverse postoperative outcomes, including impaired wound healing. This study aimed to investigate the association between the Body Roundness Index (BRI) and impaired wound…
- Conditions
- Thoracic Surgery, Obesity, BMI, Visceral Fat
- Trial name
- NCT07065890
- Where
- China
- Volunteers
- 422 people
- Sponsor
- Zhao bo
Non-small Cell Lung Cancer Stage III
Radiotherapy Combined With ICIs as Treatment for LA-NSCLC After Failing Induction Immunochemotherapy
Patients with stage III non-small-cell lung cancer initially evaluated as unresectable are selected for the program, who are remained unresectable after 2-4 cycles of conversion chemotherapy combined with immune checkpoint…
- Trial name
- NCT06031597
- Testing
- radiotherapy, Platinum-Based Drug, Immunotherapy
- Volunteers
- 105 people
- Sponsor
- Zhejiang Cancer Hospital
Shoulder Impingement
Cervical Unilateral Antero-posterior Mobilization and Thoracic Central Postro-anterior Mobilization in Treatment of Shoulder Impingement Syndrome
Shoulder impingement syndrome (SIS) is a complex, multi-factorial problem that is treated with a variety of different conservative options.
- Trial name
- NCT06349746
- Testing
- therapeutic exercises, mobilization exercise
- Where
- Egypt
- Volunteers
- 56 people
- Sponsor
- Egyptian Chinese University
Post Operative Pain, Pain, Acute
Post-thoracotomy Pain Management With Active External Warming and Ice Application
The aim of study is to investigate the effects of active external warming of patient concurrently with application of ice to incision site on thoracotomy pain and analgesic consumption.
- Conditions
- Post Operative Pain, Pain, Acute, Thoracic Injury
- Trial name
- NCT05299788
- Testing
- Active external warming, Ice application
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people
- Sponsor
- Akdeniz University
Lung Cancer, Metastases to Lung
A Multicenter Phase II Study of Stereotactic Radiotherapy for Centrally Located Lung Tumors (STRICT-LUNG STUDY) and Ultra-centrally Located Lung Tumors (STAR-LUNG STUDY).
An open-label phase II study, investigating toxicity, treatment efficacy and the local tumor control rate in 69 patients with centrally located tumors and in 69 patients with ultra-centrally located tumors in the lung.
- Conditions
- Lung Cancer, Metastases to Lung, Radiotherapy Side Effect
- Trial name
- STRICTSTARLUNG (NCT05354596)
- Testing
- STRICT LUNG, STAR LUNG
- Where
- 6 sites in Denmark
- Volunteers
- 138 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Rib; Fracture
RibFix Blu Thoracic Fixation System Versus Non-surgical Treatment in Non-flail Chest Rib Fractures
This is a prospective, multi-center, observational, cohort study involving skilled cardiothoracic surgeons who are experienced in implanting the treatment of non-flail chest rib fractures and the use of RibFix Blu Thoracic…
- Trial name
- NCT05146986
- Testing
- Non surgical and Surgical
- Where
- 5 sites in Australia, South Korea
- Volunteers
- 167 people, healthy volunteers welcome
- Sponsor
- Zimmer Biomet
Siewert Type II Adenocarcinoma of Esophagogastric Junction
Right Versus Left Thoracic Surgical Approaches for Siewert II Gastroesophageal Junction Adenocarcinoma
To explore the 5-year overall survival (OS) of right versus left thoracic surgical approaches for patients with locally advanced Siewert II gastroesophageal junction adenocarcinoma treated by neoadjuvant chemotherapy
- Trial name
- NCT06644352
- Testing
- different thoracic surgical approaches
- Where
- China
- Volunteers
- 236 people
- Sponsor
- Cancer Institute and Hospital, Chinese Academy of Medical Sciences
Rib Fractures
INTERCOSTAL NERVE BLOCK: Efficacy of CINB for Patients With Multiple Rib Fractures
This is a prospective, randomized, non-blinded study comparing CINB plus medical therapy versus standard medical care (non-steroidals and opioids intravenous/oral inpatient and oral outpatient) alone for patients with multiple…
- Trial name
- NCT05642026
- Testing
- Ropivacaine, Non steroidal anti-inflammatory drug and opioids
- Where
- United States
- Volunteers
- 180 people
- Sponsor
- Zachary Warriner
Solid Carcinoma, 5-Fluorouracil Toxicity
Prevention of Chest Pain in Chemo-treated Cancer Patients
This is a prospective, exploratory, randomised clinical trial. Patients with diagnosed cancer that are to be treated with 5-fluorouracil (5-FU) will be randomised into standard oncological treatment or a cardiological assessment…
- Conditions
- Solid Carcinoma, 5-Fluorouracil Toxicity, Cardiotoxicity, Chemotherapeutic Toxicity
- Trial name
- CATCH (NCT03486340)
- Testing
- Cardiologic assessment
- Where
- Denmark
- Volunteers
- 218 people
- Sponsor
- Vejle Hospital
Rib Fractures, Rib Fracture Multiple
Effects of Using the Duracore Splinting Device on Patient Outcomes Related to Chest Trauma
The purpose of this study is to use the Duracore splinting device to measure lung capacities of patients with rib fractures in control and experimental groups to determine if lung capacities improve with the splint.
- Trial name
- NCT04909463
- Testing
- Chest Splint
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- CommonSpirit Health
Pain Management, Thoracic Trauma
Comprehensive Multicenter Study on the Management of Acute Pain Following Thoracic Combat-Related Trauma in Ukraine
This study is a multicenter clinical trial conducted in Vinnytsia, Rivne, and Lviv, Ukraine, focusing on the management of acute pain following thoracic injuries sustained during combat.
- Conditions
- Pain Management, Thoracic Trauma, Pulmonary Function, Quality of Life
- Trial name
- CMS-APT-UA (NCT07380789)
- Testing
- Cryoablation, Radiofrequency ablation alone
- Where
- Ukraine
- Volunteers
- 50 people
- Sponsor
- Lviv National Medical University
Radiation Induced Lung Injury, Non Small Cell Lung Cancer
Hyperpolarized Noble Gas MRI Detection of Radiation-Induced Lung Injury
Lung cancer is the leading cause of cancer death in the world; each year lung cancer claims over 20 000 lives in Canada and more than one million lives globally (1).
- Trial name
- NCT03632369
- Testing
- Hyperpolarized xenon-129 MRI
- Volunteers
- healthy volunteers welcome
- Sponsor
- Thunder Bay Regional Health Research Institute
Lung Cancer, Lung Function Decreased
Use of Dual Energy Computed Tomography in Thoracic Radiotherapy Planning.
This is a prospective observational study aiming: 1) To quantify lung function using perfusion dual energy computed tomography (DECT) and use this information at the time of treatment planning with preferential sparing of…
- Conditions
- Lung Cancer, Lung Function Decreased, Radiation Pneumonitis
- Trial name
- NCT04863027
- Testing
- Thoracic radiotherapy
- Where
- Canada
- Volunteers
- 60 people
- Sponsor
- Centre hospitalier de l'Université de Montréal (CHUM)