Clinical trials: Chest Pain
Stroke (CVA) or TIA, Diabetes
Risk Factors, Costs, and Impacts of ED Boarding
The goal of this observational study is to learn about the risk factors, costs, and operational impacts of emergency department boarding (patients admitted to the hospital but remaining in the emergency department awaiting…
- Conditions
- Stroke (CVA) or TIA, Diabetes, Asthma (Diagnosis), COPD (Chronic Obstructive Pulmonary Disease)
- Trial name
- NCT07532564
- Where
- United States
- Volunteers
- 30,486 people, healthy volunteers welcome
- Sponsor
- University of Maryland, Baltimore
Dyspnea, Chest Pain
Contactless Ultrasound Data Acquisition in Emergency Departments to Discriminate the Origin of Dyspnea and Chest Pain
PAnDA-One is a prospective, multicenter, interventional study (10 centers, France) aimed at developing and validating a diagnostic support algorithm based on the ADx-One medical device, which non-invasively acquires thoracic…
- Trial name
- PAnDA-One (NCT07653204)
- Testing
- All patients from both groups will be imaged with airborne ultrasound device
- Where
- France
- Volunteers
- 2,500 people
- Sponsor
- Austral Diagnostics
Emergency Department Patients, Pulmonary Hypertension
Pulmonary Artery Pressure in Predicting Pulmonary Embolism in Patients Presenting To The Emergency Department With Dyspnea
The aim of this study is to determine the usability of echocardiographic PAP changes obtained from emergency department records in the early risk stratification of pulmonary embolism.
- Conditions
- Emergency Department Patients, Pulmonary Hypertension, Pulmonary Embolism
- Trial name
- NCT07641400
- Testing
- Pulmonary embolism (+), pulmonary embolism (-)
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Antalya Health Sciences University
Coronary Artery Bypass Graft (CABG), Chest Tubes
Chest Tube-Delivered Bupivacaine to Decrease Postoperative Pain After Cardiac Surgery
Background: After heart surgery, patients require temporary chest tubes - plastic drains placed inside the chest to prevent fluid building up around the heart and lungs.
- Conditions
- Coronary Artery Bypass Graft (CABG), Chest Tubes, Post Operative Pain Control
- Trial name
- FREEZE-B (NCT07643506)
- Testing
- 0.5% Bupivacaine without epinephrine, 10cc injection of normal saline (0.9%)
- Volunteers
- 60 people
- Sponsor
- University of Calgary
Breast Pain, Mastalgia
Hormones, Outcomes, and Pain Pathways in Exercise Study
The goal of the proposed project is to evaluate a mechanical intervention (sports bras designed specifically for full busted women) to alleviate neck, shoulder, arm, and back pain in full-busted women and investigate the…
- Conditions
- Breast Pain, Mastalgia, Back Pain, Back Pain, Low
- Trial name
- HOPE (NCT07579182)
- Testing
- Interventional Sports bra
- Where
- United States
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- University of Houston
Acute Myocardial Infarction (AMI), Left Bundle Branch Block
Machine Learning for Diagnosis of Occlusive MI in LBBB Patients
This study investigates a new way to diagnose severe heart attacks in patients who have a specific electrical heart pattern called a Left Bundle Branch Block (LBBB).
- Conditions
- Acute Myocardial Infarction (AMI), Left Bundle Branch Block, Coronary Occlusion/Thrombosis, Chest Pain
- Trial name
- AI-LBBB (NCT07620119)
- Testing
- Digital 12-Lead ECG Analysis and Invasive Coronary Angiography
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people
- Sponsor
- Konya City Hospital
Angina (Stable), INOCA (Ischemia With Non Obstructive Coronary Artery Disease)
Diagnostic and Clinical Management of Non-Obstructive Myocardial Ischemia in Patients With Long Covid-19 Syndrome and New Onset Chest Pain
Long Covid-19 INOCA is an investigator-initiated, prospective, randomized, sham-controlled, single center study. Its objective is to investigate the benefits of tailored medical therapy according to the results of the coronary…
- Conditions
- Angina (Stable), INOCA (Ischemia With Non Obstructive Coronary Artery Disease), Long COVID-19 Syndrome
- Trial name
- NCT07559994
- Testing
- Coronary functional test
- Where
- Spain
- Volunteers
- 108 people
- Sponsor
- Fundacion Investigacion Interhospitalaria Cardiovascular
Nonfatal Stroke, Nonfatal Myocardial Infarction
Coronary CT Angiogram - Prognostic Value of Adverse Plaque Features in Guiding Treatment (CT-PLAQUE)
The study aims at determining if the presence of adverse plaque features identified from the CT angiogram can help determine prognosis and guide treatment options.
- Conditions
- Nonfatal Stroke, Nonfatal Myocardial Infarction, Cardiovascular Death, All-cause Death
- Trial name
- CT-PLAQUE (NCT07212751)
- Testing
- CTCA
- Where
- Hong Kong
- Volunteers
- 22,000 people
- Sponsor
- The University of Hong Kong
Chest Pain, Stroke Acute
Evaluation and Optimization of Telephone Triage Using Artificial Intelligence (AI) Models for the Detection of Demands for Time-dependent Pathology at the Emergency and Urgent Care Coordination Center (CCUE).
Improving Telephone Triage in Emergency Calls with AI The Coordinating Centre for Urgencies and Emergencies in Andalusia (CCUE) handles thousands of calls every day.
- Conditions
- Chest Pain, Stroke Acute, Respiratory Failure, Cardiac Arrest (CA)
- Trial name
- TrIAje Project (NCT07247669)
- Where
- Spain
- Volunteers
- 5,000,000 people
- Sponsor
- Centro de Emergencias Sanitarias 061 Andalucía
Chest Tube Removal
Effect of Warm Footbath Combined With Relaxation Exercise on Pain and Anxiety During Chest Tube Removal After Cardiac Surgery
Chest tube removal is a widely used surgical procedure, particularly in the post-cardiac surgery period, to maintain cardiopulmonary stability, provide mediastinal drainage, and prevent potential complications.
- Trial name
- NCT07585240
- Testing
- Relaxation Exercises, Warm Water Foot Bath
- Volunteers
- 60 people
- Sponsor
- Igdir University
Heart Diseases, Coronary Artery Disease
Intraoperative Echocardiography in Low-Risk CABG Surgery
This goal of this study is to better understand when and where intraoperative transesophageal echocardiography (TEE) should (or should not) be used during coronary artery bypass graft (CABG) surgeries.
- Conditions
- Heart Diseases, Coronary Artery Disease, Chest Pain, Stenosis Coronary
- Trial name
- NCT06154265
- Testing
- TEE probe
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- University of Pennsylvania
Abdominal Pain, Thoracic Pain
PoCUS Impact on the Diagnostic Approach for Thoracic and Abdominal Pain in the ED
Many medical specialties and paramedical fields are increasingly using point-of-care ultrasound (PoCUS). In daily practice, thoracic and abdominal pain constitute a significant portion of emergency department consultations.
- Trial name
- DATAPUS (NCT06827730)
- Testing
- Point of care ultrasound
- Where
- Belgium
- Volunteers
- 406 people
- Sponsor
- Cliniques universitaires Saint-Luc- Université Catholique de Louvain
Pectus Excavatum, Pain, Postoperative
Identification of Best Postoperative Analgesia Method Following a Minimally Invasive Repair of Pectus Excavatum
Pectus excavatum is the most common chest wall deformity in children, accounting for 90% of all congenital chest wall deformities. It occurs in one to eight per 1000 live births.
- Trial name
- (MIRPE) (NCT04211935)
- Testing
- Use of PCA, Use of ESB for postoperative pain control after MIRPE, Use of INC for postoperative pain control after MIRPE
- Where
- United States
- Volunteers
- 158 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Chest Pain
Chest Pain Nurse Track
Chest pain is a commonly encountered presentation in the emergency department (ED), with an incidence ranging from 5 to 12%. Chest pain has a wide range of aetiologies from the mildest to the most severe.
- Trial name
- CHESTNUT (NCT06149819)
- Testing
- Diagnostic and safety of a nursing pathway for the management of non-traumatic chest pain
- Where
- France
- Volunteers
- 182 people
- Sponsor
- University Hospital, Grenoble
Coronary Artery Disease, Chest Pain
Arterial Stiffness for Improved Prediction of Coronary Artery Disease by Coronary CT Angiography
This study will evaluate the ability of device-estimated pulse wave velocity and machine learning methods to improve the prediction of potential symptomatic coronary artery disease
- Conditions
- Coronary Artery Disease, Chest Pain, Dyspnea, Arterial Stiffness
- Trial name
- NCT06734247
- Testing
- Coronary computer tomography angiography (CCTA), Photoplethysmography (PPG) and single-lead ECG, Brachial single cuff-based arterial stiffness
- Where
- Sweden
- Volunteers
- 156 people
- Sponsor
- Danderyd Hospital
Aortic Dissection Type A, Chest Pain
Triage and Recognition of Acute Aortic Dissection in Chest Pain by Electrocardiogram-Artificial Intelligence
The goal of this prospective multicenter observational study is to learn whether an artificial intelligence model based on electrocardiograms (ECGs) can help diagnose acute type A aortic dissection (TAAD) in adults who come to…
- Trial name
- TRACE (NCT07536932)
- Volunteers
- 10,000 people
- Sponsor
- Shanghai Zhongshan Hospital
Angina, Stable, Coronary Artery Disease
Objective Risk Assessment in Patients With Possible Anginal Chest Pain Using Leading Technology
The ORACLE study is an observational cohort study designed to explore the feasibility of providing an assessment of chest pain for patients with suspected angina within one working day of referral to specialist services.
- Trial name
- ORACLE (NCT06325020)
- Testing
- The assessment of patients with possible angina using the ORACLE pathway
- Where
- United Kingdom
- Volunteers
- 500 people
- Sponsor
- University of Edinburgh
Chest Pain, Coronary Artery Disease
Coronary Computed Tomographic Angiography Combined With CT-FFR in Intermediate-Risk Chest Pain Patients.
This study aims to investigate the guiding value of coronary CTA combined with CT-FFR in diagnostic and treatment decision-making for emergency chest pain patients at moderate risk, as well as its impact on clinical outcomes.
- Conditions
- Chest Pain, Coronary Artery Disease, Emergency Department
- Trial name
- E-CCTA (NCT07140419)
- Testing
- Coronary computed tomographic angiography with CT - derived fractional flow reserve
- Where
- China
- Volunteers
- 2,000 people
- Sponsor
- Qilu Hospital of Shandong University
Pain, Procedural, Pain, Postoperative
The Effect of Vibration and Cold on Pain and Anxiety Associated With Chest Tube Removal Following CABG
Removal of chest tubes after coronary artery bypass graft (CABG) surgery can cause severe pain and anxiety, which may negatively affect the recovery process.
- Conditions
- Pain, Procedural, Pain, Postoperative, Coronary Artery Bypass Surgery, Chest Tubes
- Trial name
- CABG (NCT06217263)
- Testing
- Vibration device, Vibration device&Cold application pack
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 93 people
- Sponsor
- Istanbul University - Cerrahpasa
Chest Tube, Virtual Reality
Virtual Reality Forest Sounds and Patient Outcomes During Chest Tube Removal
The aim of this study is to investigate the effects of listening to nature sounds in a virtual reality forest on pain, vital signs, comfort, and patient satisfaction during chest tube removal.
- Conditions
- Chest Tube, Virtual Reality, Chest Tube Removal
- Trial name
- NCT07457788
- Testing
- Virtual Reality with Nature Sounds
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Uskudar University