Clinical trials: Chemotherapy Induced Peripheral Neuropathy (CIPN)
CIPN - Chemotherapy-Induced Peripheral Neuropathy, Breast Cancer
Network-Guided Theta Burst Stimulation for Breast Cancer With Chemotherapy-Induced Peripheral Neuropathy: Clinical and fMRI Biomarker Evidence
Chemotherapy-induced peripheral neuropathy (CIPN) is a common and debilitating complication among breast cancer survivors, frequently associated with chronic neuropathic pain that remains inadequately controlled by…
- Trial name
- CIPN TBS (NCT07695415)
- Testing
- pcTBS
- Where
- Taiwan
- Volunteers
- 40 people
- Sponsor
- Taipei Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation
CIPN
Sensory Rehabilitation in Chemotherapy Induced Peripheral Neuropathy (CIPN)
Physiotherapist research about Sensory rehabilitation in chemotherapy induced peripheral neuropathy (CIPN) with the aid of questioners and physiotherapy practice
- Trial name
- NCT05382520
- Testing
- Questionares and practice
- Where
- Israel
- Volunteers
- 12 people
- Sponsor
- Assaf-Harofeh Medical Center
Breast Cancer Female, Gynecologic Cancer
Transcranial Magnetic Stimulation for Chemotherapy-Induced Peripheral Neuropathy in Breast and Gynecologic Cancer Survivors
The goal of this study is to evaluate the change in pain scores among patients with chemotherapy-induced peripheral neuropathy after receiving treatment with repetitive transcranial magnetic stimulation (rTMS).
- Trial name
- rTMS for CIPN (NCT07120100)
- Testing
- rTMS
- Where
- United States
- Volunteers
- 19 people
- Sponsor
- University of Utah
Taxane-induced Peripheral Neuropathy, Chemotherapy-induced Peripheral Neuropathy (CIPN)
A Pilot Study of Acupuncture for Chemotherapy-induced Peripheral Neuropathy in Breast Cancer Patients
This study is being done to evaluate the potential benefits of using acupuncture to reduce symptoms of tingling, burning, numbness and pain in the hands and feet of women with peripheral neuropathy after completion of…
- Conditions
- Taxane-induced Peripheral Neuropathy, Chemotherapy-induced Peripheral Neuropathy (CIPN), Early-Stage Breast Carcinoma, Stage I Breast Cancer
- Trial name
- NCT02129686
- Testing
- Immediate Acupuncture Group, Delayed Acupuncture Group
- Where
- United States
- Volunteers
- 57 people
- Sponsor
- Dana-Farber Cancer Institute
Chemotherapy-induced Peripheral Neuropathy, CIPN - Chemotherapy-Induced Peripheral Neuropathy
High-concentration Capsaicin Patch for the Prevention of Paclitaxel-induced Peripheral Neuropathy
This research study is for participants who are receiving paclitaxel infusion as part of their cancer treatment. The purpose of this study is to test the effectiveness of the Food and Drug Administration (FDA) approved…
- Trial name
- NCT07834281
- Testing
- High Concentration Capsaicin Patch (HCCP)
- Where
- United States
- Volunteers
- 240 people
- Sponsor
- Case Comprehensive Cancer Center
Cancer
A Study to Assess the Efficacy and Safety of Oxycodone/Naloxone in Korean Patients With Chemotherapy-Induced Peripheral Neuropathy (CIPN)
A multicenter, phase IV, interventional study to assess the efficacy and safety of Targin (Oxycodone/Naloxone) Korean patients with CIPN (Chemotherapy-Induced Peripheral Neuropathy) who need opioid combination treatment with…
- Trial name
- NCT01675531
- Testing
- Targin
- Where
- South Korea
- Volunteers
- 73 people
- Sponsor
- Mundipharma Korea Ltd
Pain
Neuromodulation as a Treatment for Chemotherapy-Induced Peripheral Neuropathy
The goal of this clinical research study is to learn if using a type of non-invasive therapy called neurofeedback training can help teach patients with peripheral neuropathy how to change their own brain waves to lower their…
- Trial name
- NCT02573766
- Testing
- Neurofeedback Training, Electroencephalogram, Pain Scale
- Where
- United States
- Volunteers
- 91 people
- Sponsor
- M.D. Anderson Cancer Center
Cancer, Chemotherapy-induced Peripheral Neuropathy
Chemotherapy-induced Peripheral Neuropathy (CIPN) on Motor and Sensory Function
As cancer survival rates have been increased due to technological developments and early detection strategies, there has been been a growing need to assess the effect of long-term complications and adverse effects upon patients'…
- Conditions
- Cancer, Chemotherapy-induced Peripheral Neuropathy, Chemotherapeutic Toxicity, Breast Cancer
- Trial name
- NCT04799080
- Where
- Turkey (Türkiye)
- Volunteers
- 72 people
- Sponsor
- Izmir Bakircay University
Chemotherapy-induced Peripheral Neuropathy (CIPN)
AYUrvedic Foot Massage for Symtoms of Taxane-induced Peripheral nEuroPathy
Chemotherapy-induced peripheral neuropathy (CIPN) affects approximately 40% of patients treated with taxanes. These agents may cause burning pain, paresthesia, numbness, and loss of proprioceptive sensitivity, which can reduce…
- Trial name
- AYU-STEP (NCT07884071)
- Testing
- Manual manipulation of the feet.
- Where
- Italy
- Volunteers
- 20 people
- Sponsor
- European Institute of Oncology
Prostate Cancer Metastatic Disease, Chemotherapy Induced Peripheral Neuropathy (CIPN)
o Tadalafil for Prevention of Docetaxel-Induced Peripheral Neuropathy in Prostate Cancer
Docetaxel is a standard chemotherapy for metastatic prostate cancer but is associated with dose-limiting peripheral neuropathy. Currently, no pharmacologic agents are established for prevention.
- Conditions
- Prostate Cancer Metastatic Disease, Chemotherapy Induced Peripheral Neuropathy (CIPN), Neurotoxicity
- Trial name
- NCT07333976
- Testing
- Tadalafil 5 mg
- Where
- Taiwan
- Volunteers
- 90 people
- Sponsor
- Tri-Service General Hospital (TSGH)
CIPN - Chemotherapy-Induced Peripheral Neuropathy
Biomarkers in Chemotherapy-Induced Peripheral Neurotoxicity
This pilot study will attempt to establish the feasibility of using tissue oxygen measurements and the protein, neurofilament light chain (NF-L), as potential biomarkers for chemotherapy-induced peripheral neuropathy (CIPN).
- Trial name
- CIPN (NCT03348956)
- Testing
- EPR Oximetry
- Where
- United States
- Volunteers
- 7 people
- Sponsor
- Dartmouth-Hitchcock Medical Center
Chemotherapy Induced Peripheral Neuropathy (CIPN)
Improving Chemotherapy Induced Peripheral Neuropathy in Children With Leukemia: A Study of Transcutaneous Acupoints Electrical Stimulation and Auricular Acupressure Interventions
The goal of this clinical trial is to compare the effectiveness of Transcutaneous Acupoints Electrical Stimulation (TAES) and Auricular Acupressure (AA) on subject CIPN symptoms, sensory function, motor and physical function…
- Trial name
- NCT07279818
- Testing
- Transcutaneous Acupoints Electrical Stimulation (TAES), Auricular Acupressure (AA), No intervention
- Where
- China
- Volunteers
- 132 people
- Sponsor
- The Hong Kong Polytechnic University
Chemotherapy Induced Peripheral Neuropathy (CIPN)
Neoadjuvant FOLFOX Chemotherapy for Colon Cancer: Long-Term Chemotherapy-Induced Peripheral Neuropathy and Impact on Quality of Life
The goal of this observational study was to learn about the long-term effects of neoadjuvant (pre-surgery) chemotherapy on patients with locally advanced colon cancer.
- Trial name
- NEOCIPN-COLON (NCT06844409)
- Where
- Russia
- Volunteers
- 54 people
- Sponsor
- P. Herzen Moscow Oncology Research Institute
Lymphoma, Peripheral Neuropathy
Chemotherapy Induced Peripheral Neuropathy (CIPN) and Lymphoma Longitudinal Follow-up and Prognostic Factors
Vincristine-induced peripheral neuropathy, which is commonly a sensorimotor neuropathy, remains a major complication of lymphoma patients treated with R-CHOP.
- Trial name
- NeuroTox-L (NCT05378256)
- Testing
- Clinical scales of CIPN
- Where
- France
- Volunteers
- 40 people
- Sponsor
- Centre Hospitalier Régional d'Orléans
Peripheral Neuropathy in Breast Cancer Patient
Nutraceuticals Versus Usual Care in the Prevention or Reduction of CIPN in Patients Treated With Docetaxel as Neoadjuvant/Adjuvant Breast Cancer Therapy
The trial will utilize Nutraceuticals (Vitamin D 2000IU oral once daily, Vitamin B6 100 mg oral once daily, Vitamin B12 100 mcg oral once daily, Omega-3 Fatty Acids 900 mg oral three times a day) in patients treated with…
- Trial name
- CIPN (NCT02795572)
- Testing
- Vitamin D, Vitamin B6, Vitamin B12
- Where
- Canada
- Volunteers
- 13 people
- Sponsor
- AHS Cancer Control Alberta
Colorectal Cancer, Chemotherapy-induced Peripheral Neuropathy
Preventive Treatment of OxaLiplatin Induced peripherAl neuRopathy in Adjuvant Colorectal Cancer
This study is to evaluate PledOx for prevention of chronic chemotherapy induced peripheral neuropathy induced by oxaliplatin in patients with Stage III or high-risk Stage II colorectal cancer (CRC).
- Trial name
- POLAR-A (NCT04034355)
- Testing
- Calmangafodipir (5 µmol/kg)
- Where
- 65 sites in Belgium, Czechia and 8 more
- Volunteers
- 301 people
- Sponsor
- Egetis Therapeutics AB (publ)
Chemotherapy Induced Peripheral Neuropathy
Self-applied taVNS for CIPN
The purpose of this study is to determine the feasibility of using a portable device at home to self-administer transcutaneous auricular vagus nerve stimulation (taVNS).
- Trial name
- NCT07596030
- Testing
- Transcutaneous Auricular Vagus Nerve Stimulation (taVNS)
- Where
- United States
- Volunteers
- 36 people
- Sponsor
- University of Miami
CIPN - Chemotherapy-Induced Peripheral Neuropathy, Breast Cancer
Meridian Yoga on Chemotherapy-induced Peripheral Neuropathy in Breast Cancer Patients
Chemotherapy-induced peripheral neuropathy (CIPN) is a common side effect in breast cancer patients with completion of chemotherapy, and that is characterized by associated clinical symptoms such as pain, tingling, numbness, and…
- Trial name
- CIPN (NCT05959811)
- Testing
- yoga
- Where
- Taiwan
- Volunteers
- 80 people
- Sponsor
- China Medical University Hospital
Peripheral Neuropathy
Effects of Reiki, Yoga, Meditation, on the Physical and Psychological Symptoms of Chemotherapy-Induced Peripheral Neuropathy
The purpose of this study is to test whether people with symptoms of chemotherapy-induced peripheral neuropathy (CIPN) receive physical or psychological benefits from participating in a six-week Reiki, Yoga, Meditation, or…
- Trial name
- NCT01569269
- Testing
- Yoga Intervention, Meditation Intervention, Reiki
- Where
- United States
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- George Mason University
Chemotherapy-Induced Peripheral Neuropathy (CIPN)
Efficacy of Acupuncture on Chemotherapy-Induced Peripheral Neuropathy (CIPN)
The purpose of this study is to assess the neurological efficacy of acupuncture in patients with cancer who experienced peripheral neuropathy, which is induced by chemotherapy.
- Trial name
- NCT04651907
- Testing
- acupuncture, minimal acupuncture
- Where
- 3 sites in Taiwan
- Volunteers
- 69 people
- Sponsor
- China Medical University Hospital