Clinical trials: Cesarean Section Surgery
Surgical Site Infection
Chlorhexidine-Alcohol Versus Povidone-Iodine for Cesarean Antisepsis
Primary Hypothesis: chlorhexidine gluconate alcohol skin antiseptic preparation is superior to povidone-iodine scrub and paint skin antiseptic preparation for prevention of cesarean related surgical site infection.
- Trial name
- CAPICA (NCT02202577)
- Testing
- Chlorhexidine - Isopropyl alcohol, Povidone-Iodine Scrub and Paint
- Where
- United States
- Volunteers
- 932 people, healthy volunteers welcome
- Sponsor
- Case Western Reserve University
Emotional Support During Cesarean Delivery
The Effect of Emotional Support Given During Cesarean Section on Pain, Anxiety, and Surgical Fear
The study was conducted to determine the effect of emotional support given during cesarean section on pain, anxiety and surgical fear.
- Trial name
- NCT06795828
- Testing
- Emotional support group
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Cumhuriyet University
High-risk Nulliparous Pregnancy, Patients Scheduled for Cesarean Section, Surgical Fear, Preoperative Anxiety, and Cortisol Level
The Effect of Mandala Art Therapy on Surgical Fear and the Stress Hormone (Cortisol) in High-risk Pregnant Women Before Cesarean Section.
This randomized controlled study aims to evaluate the effect of mandala art therapy applied before cesarean section on surgical fear and cortisol levels in high-risk pregnant women.
- Trial name
- NCT07691320
- Testing
- Mandala Art Therapy
- Volunteers
- 142 people
- Sponsor
- Inonu University
Cesarean Section
The Effect of Amniotic Membrane Application on Post-Cesarean Wound Healing and Cosmetic Outcomes
This clinical trial evaluates the effectiveness of amniotic membrane application during cesarean delivery in reducing post-surgical complications and improving wound healing and cosmetic outcomes in women aged 18-40 undergoing…
- Trial name
- Amniotic Membr (NCT06770946)
- Testing
- Amniotic Membrane Application
- Where
- Turkey (Türkiye)
- Volunteers
- 372 people
- Sponsor
- Yuzuncu Yil University
Cesarean Section, Pregnancy Related
Brain Oxygenation in Newborns Due to Neuroaksial Methods
Epidural and spinal anesthesia techniques are frequently used all over the world in elective cesarean section operations. To evaluate the effects of epidural and spinal anesthesia techniques applied in cesarean section surgery on…
- Conditions
- Cesarean Section, Pregnancy Related, Cerebral Hypoxia, Anesthesia, Regional
- Trial name
- oxygenation (NCT06316596)
- Testing
- Spinal Anesthesia, Epidural Anesthesia
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Bursa Yuksek Ihtisas Training and Research Hospital
D001458, D011247
Effect of Prophylactic Negative Pressure Versus Silver Impregnated Silicone Bandage on C-Section Infection Rates
Effect of Prophylactic Negative Pressure versus Silver Impregnated Silicone Bandage on Cesarean Section Surgical Site Infection Rate
- Trial name
- NCT04582045
- Testing
- silver impregnated dressing
- Where
- United States
- Volunteers
- 1,064 people
- Sponsor
- HealthPartners Institute
Post Surgical Pain
Dose Escalation of Dexamethasone to Increase Duration of Transversus Abdominal Plane Block Following Cesarean Section
The study aims to improve the care of the obstetric population after cesarean section and improve total patient satisfaction by improving post-surgical pain control with the use of dexamethasone in combination with bilateral TAP…
- Trial name
- NCT03098420
- Testing
- 2mg Dexamethasone, 4mg Dexamethasone, Ropivacaine (TAP blocks)
- Where
- United States
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Analgesia, Obstetrical, Coagulation Defect; Postpartum
IV Ketorolac on Platelet Function Post-Cesarean Delivery
Cesarean delivery has become the most common surgical procedure in the US. Non-steroidal anti-inflammatory drugs (NSAIDs) have been shown to improve the quality of post-cesarean analgesia and markedly reduce opioid consumption.
- Conditions
- Analgesia, Obstetrical, Coagulation Defect; Postpartum, Nonsteroidals (NSAIDs)Toxicity, Postpartum Hemorrhage
- Trial name
- KetoPltAgg (NCT03805607)
- Testing
- Ketorolac Tromethamine 30 MG/ML
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Beth Israel Deaconess Medical Center
Surgical Wound Infection, Infection; Cesarean Section
Antibiotics and Gut Microbiota Among Newborn Infants
Background Women undergoing Caesarean Section (CS) have an increased risk of postpartum infections compared to women undergoing vaginal delivery. In Denmark the incidence of post-CS infections is 7-10%.
- Conditions
- Surgical Wound Infection, Infection; Cesarean Section, Complications; Cesarean Section
- Trial name
- NCT02072798
- Testing
- Cefuroxime
- Where
- Denmark
- Volunteers
- 42 people
- Sponsor
- Odense University Hospital
Surgical Site Infection (SSI)
Skin Adhesive Plus Intra-cuticular Suture Versus Suture Alone for Cesarean Skin Closure
The goal of this randomized control trial is to compare two skin closure techniques after cesarean section. Both techniques are currently in wide use but no comparison between the two was reasserted yet.
- Trial name
- NCT07483411
- Testing
- Dermabond
- Where
- Israel
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- Doron Kabiri
Surgical Site Infection
Using mHealth Technology to Identify and Refer Surgical Site Infections in Rwanda
The present study aims to examine whether or not the use of mobile Health (mHealth) by community health workers (CHWs) can improve the identification of surgical site infection (SSI) and a timely return to care among patients who…
- Trial name
- NCT03311399
- Testing
- SSI Screening Tool used in home visits by CHWs, SSI Screening Tool used via phone call follow-up
- Where
- Rwanda
- Volunteers
- 653 people, healthy volunteers welcome
- Sponsor
- Brigham and Women's Hospital
Child Delivery Using an Elective C- Section
Evaluation of the BioWeld1 System as a Method for Surgical Incision Closure
The purpose of this study is to assess the safety and performance of the BioWeld1 System procedure for surgical incision closure of the skin in women scheduled for elective C-section procedure.
- Trial name
- NCT01709240
- Testing
- BioWeld1 System
- Where
- Israel
- Sponsor
- IonMed Ltd
Surgical Site Infection
Surgical Site Infection Rates in Obese Patients After Cesarean Delivery
The aim of this study is to determine the surgical site infection rate and patient satisfaction for subcuticular versus interrupted mattress suture in closure of skin at Cesarean delivery in obese patients.
- Trial name
- NCT01713751
- Testing
- Interrupted suturing, Subcuticular suturing
- Volunteers
- 500 people
- Sponsor
- Ain Shams University
Surgical Site Infection, Obesity
SUpPress SSI - Single Use Negative Pressure Wound Therapy (NPWT) to Reduce Surgical Site Infections
Our goal is to provide data that will give surgeons and hospitals clear recommendations on the use of NPWT for Cesarean section, abdominal hysterectomy and colon surgeries in patients with diabetes and/or obesity.
- Conditions
- Surgical Site Infection, Obesity, Diabetes, Cesarean Section Complications
- Trial name
- SUpPressSSI (NCT03816293)
- Testing
- Negative Pressure Wound Therapy
- Where
- 5 sites in United States
- Volunteers
- 3,680 people
- Sponsor
- University of Illinois Chicago
Post Spinal Hypotension
Can Subclavian / Infraclavicular Axillary Vein Collapsibility Index Predict Post-Spinal Hypotension in Caesarean Section Operations?
Postspinal hypotension (PSH) is a common side effect with an incidence of 15.3% to 33%, which may result in organ hypoperfusion and ischemic events (1,2).
- Trial name
- Cesarean (NCT05120258)
- Volunteers
- 100 people
- Sponsor
- Selcuk University
Cesarean Section, Emotional Regulation
The Effect of Emotional Freedom Technique Applied Before Cesarean Section
Since all the follow-up and care of the pregnant during the prenatal period are carried out by the midwives, the care provided by the midwives to the women during the prenatal period plays a key role for the woman to have a…
- Conditions
- Cesarean Section, Emotional Regulation, Surgery, Traumatic Birth
- Trial name
- NCT05646979
- Testing
- EFT group
- Where
- Turkey (Türkiye)
- Volunteers
- 53 people, healthy volunteers welcome
- Sponsor
- Inonu University
Cesarean Section Complications
How Well do the Current Cesarean Deliveries Adhere to the Published ERAS Guidelines?
Local guidelines for the postoperative care of women who have undergone cesarean delivery at the HUS/Women's hospital are based recommendations by the ERAS society.
- Trial name
- NCT05396417
- Testing
- cesarean delivery
- Where
- Finland
- Volunteers
- 500 people
- Sponsor
- Women's Hospital HUS
Chronic Post-cesarean Pain
Evaluation of the Incidence of Chronic Post-cesarean Pain as Part of an Enhanced Recovery After Surgery (ERAS) Protocol.
Enhanced Rehabilitation After Surgery (ERAS), developed in the 1990s, is a program encompassing a set of measures before, during and after surgery aimed at improving management by promoting the early recovery of the patient's…
- Trial name
- ChroCéRAAC (NCT04919408)
- Testing
- telephone survey
- Where
- 2 sites in France
- Volunteers
- 283 people
- Sponsor
- Centre Hospitalier Intercommunal de Toulon La Seyne sur Mer
Elective Caesarean Section Surgeries
Intrathecal Levobupivacaine With Opioids for Caesarean Section
In this prospective, randomized, double-blind, controlled study, the aim was to compare the effect of adding fentanyl (10 µg) or sufentanil (2.5 µg) to levobupivacaine (2.2±0.2 ml 0.5%) on the intraoperative anesthesia quality…
- Trial name
- NCT01858090
- Testing
- Control Group Chirocaine, Group Fentanyl, Group sufentanil
- Where
- Turkey (Türkiye)
- Volunteers
- 93 people
- Sponsor
- Baskent University
Caesarean Wound, Hypertrophic Surgical Scar
: Protescal: Prevention of Hypertrophic Scar and Keloid Formation Post Caesarean Section
This study aimed to evaluate the effectiveness of Protescal in preventing post caesarean section hypertrophic scar and keloid formation.
- Conditions
- Caesarean Wound, Hypertrophic Surgical Scar, Keloid Scar Following Surgery
- Trial name
- NCT04951869
- Testing
- Protescal gel
- Where
- Malaysia
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Universiti Kebangsaan Malaysia Medical Centre