Clinical trials: Cervical Cancer Screening
Cancer of the Cervix, Cervical Intraepithelial Neoplasia
Compass - Randomised Controlled Trial of Primary HPV Testing for Cervical Screening in Australia
Compass is a randomised controlled trial of primary HPV testing for cervical cancer screening in Australia. A pilot study involving 5,000 women was carried out in 2013-2014.
- Trial name
- Compass (NCT02328872)
- Testing
- Molecular testing for HPV, Liquid Based Cytology
- Where
- Australia
- Volunteers
- 76,181 people, healthy volunteers welcome
- Sponsor
- VCS Foundation
Cervical Cancer, Anxiety
Watching Live VIA/VILI Examinations on a Digital Screen May Reduce Patients' Anxiety
The purpose of this study is to assess whether the degree of anxiety experienced by women undergoing visual inspection with acetic acid (VIA) and Lugol's iodine (VILI) can be reduced by watching the procedure in real-time on a…
- Trial name
- NCT02945111
- Testing
- Real-time view, No visual support
- Where
- Cameroon
- Volunteers
- 122 people
- Sponsor
- Prof. Patrick Petignat
Human Immunodeficiency Virus, HPV Infection
Thermocoagulation for Treatment of Precancerous Cervical Lesions
The purpose of this study is to evaluate the safety, acceptability, and efficacy of Thermocoagulation for treatment of precancerous lesions among HIV-positive women in a screen-and-treat program in Western Kenya.
- Conditions
- Human Immunodeficiency Virus, HPV Infection, CIN 2/3
- Trial name
- NCT04191967
- Testing
- Thermocoagulation
- Where
- Kenya
- Volunteers
- 379 people
- Sponsor
- University of California, San Francisco
HPV Infection, Cervical Cancer
HPV-Based Screen-and-Treat Demonstration Project in Lilongwe
The purpose of this study is to assess completion and performance of the following novel invasive cervical cancer (ICC) screen-and-treat algorithm among 625 HIV-positive women in Lilongwe, Malawi: 1) rapid testing of…
- Conditions
- HPV Infection, Cervical Cancer, HIV Infections
- Trial name
- NCT04092257
- Testing
- VIA and thermocoagulation
- Where
- Malawi
- Volunteers
- 1,250 people, healthy volunteers welcome
- Sponsor
- UNC Lineberger Comprehensive Cancer Center
Cervical Cancers
Effect of Nurse Navigation Program on Cervical Cancer Screening Behaviour of the Women Aged 30-65
This study was designed as a randomized controlled experimental study to examine the effect of the 'Nurse Navigation Program' on cervical cancer screening behaviors (Human Papilloma Virus (HPV) DNA screening test and/or pap smear…
- Trial name
- NCT06647992
- Testing
- Nurse Navigation Program
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- TURKAN OZDAS
HPV Infection, Cervix Cancer
Prevention and Screening Towards Elimination of Cervical Cancer
The research project applies the protocol of the World Health Organisation for screening of cervical cancer, with testing of hrHPV as first screening, followed by Visual Inspection of the cervix with Acetic Acid for…
- Conditions
- HPV Infection, Cervix Cancer, Cervical Dysplasia
- Trial name
- PRESCRIP-TEC (NCT05234112)
- Testing
- Community mobilisation for hrHPV self-testing, hrHPV self-testing, Follow-up after testing
- Where
- Uganda
- Volunteers
- 30,000 people, healthy volunteers welcome
- Sponsor
- University Medical Center Groningen
Uterine Cervical Neoplasm, Uterine Neoplasms
Self-Testing Options in the Era of Primary HPV Screening for Cervical Cancer Trial
The Self-Testing options in the Era of Primary HPV screening for cervical cancer (STEP) trial will evaluate effectiveness of home-based HPV kits for improving cervical cancer screening uptake and its cost-effectiveness.
- Conditions
- Uterine Cervical Neoplasm, Uterine Neoplasms, Genital Neoplasms, Female, Urogenital Neoplasms
- Trial name
- STEP (NCT04679675)
- Testing
- Usual Care, Education, Direct Mail
- Where
- United States
- Volunteers
- 32,771 people
- Sponsor
- Kaiser Permanente
Cervical Cancer
Comparison of Cervical Cancer Screening Tests in HIV-infected Women in Lusaka, Zambia
This study will compare the test performance characteristics of visual inspection with acetic acid (VIA), Xpert HPV, and OncoE6 in HIV-infected women, to inform the possible inclusion of these molecular tests in future cervical…
- Trial name
- NCT02688816
- Testing
- Xpert HPV, OncoE6
- Where
- Zambia
- Volunteers
- 200 people
- Sponsor
- Carla Chibwesha, MD
Physiological Stress, HPV Infection
Psycho-emotional Impact of Preoperative Counselling in Cervico-carcinoma Screening Programs
The communication of an altered Pap smear or positive HPV test has a strong impact on patients on a psychological level. HPV positive women are more likely to have higher level of stress, anxiety, depression and impaired sexual…
- Conditions
- Physiological Stress, HPV Infection, Papilloma Viral Infection
- Trial name
- NCT06500767
- Where
- Italy
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- University of Turin, Italy
Cervical Cancer
Using CHWs or Mailing Self Sampling Home Tests to Increase Cervical Cancer Screening in South Florida
The study will test the significance of community health worker (CHW) participation by comparing self-sampling provided by a community health worker and self-sampling provided by mail.
- Trial name
- NCT02202109
- Testing
- CHW and Self-sampling for Cervical Cancer, Mailed Self Sampler
- Where
- United States
- Volunteers
- 602 people
- Sponsor
- University of Miami
Persons With Visual Disabilities, Breast Neoplasms
Breast and Cervical Cancer Awareness Training in Visually Impaired Women
This quasi-experimental study aims to determine whether a breast and cervical cancer awareness training program can increase participation in cancer screening among women with visual impairments.
- Conditions
- Persons With Visual Disabilities, Breast Neoplasms, Uterine Cervical Neoplasms, Awareness
- Trial name
- GORSEM (NCT07541859)
- Testing
- Cancer Screening Awareness Education for Visually Impaired Women
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 74 people, healthy volunteers welcome
- Sponsor
- Marmara University
Oral Potentially Malignant Disorders, Oral Cancer
Predictive Value of GOCCLES® Device for Early Diagnosis of Oral Potentially Malignant Disorders
Oral potentially malignant disorders (OPMDs) are chronic pathologies which can suffer dysplastic alterations and evolve into oral cancer.
- Trial name
- NCT05562375
- Testing
- GOCCLES, Toluidine blue stain, Biopsy
- Where
- Spain
- Volunteers
- 73 people
- Sponsor
- Universidad Rey Juan Carlos
Uterine Cervical Neoplasms, Sexually Transmitted Diseases
Preventive Sexual Health Screening Among Female-to-Male (FTM) Transgender Adult Patients
The purpose of this study is to assess the acceptability and effectiveness of utilizing vaginal self-swabs for HPV DNA testing as compared to provider-collected cervical swabs for HPV, as well as to investigate the prevalence of…
- Trial name
- NCT02401867
- Where
- United States
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Fenway Community Health
Cervical Cancer Screening
Comparing Effectiveness of Physician-assisted Versus Self-assisted Pap Smear Collection
This purpose of this research study is to determine the effectiveness of the Personal Pap Smear Device™ to collect adequate cervical cell samples for cytology examination when compared with the Rover Cervex-Brush…
- Trial name
- NCT06229275
- Testing
- Pap smear collection using the Personal Pap Smear (PPS) Device, Active Comparator: Pap smear collection using the Rovers Cervex-Brush
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Morehouse School of Medicine
Cancer of Cervix, Vaccinia
The Prospective Cohort Study to Evaluate the Preventive Efficacy of HPV Vaccine in Japanese Women Aged 27-45 Years
A nonrandomized, non-double blinded prospective cohort study to evaluate the preventive efficacy of quadrivalent HPV6/11/16/18 vaccine for the persistent infection of HPV16 genotype or HPV18 genotype in Japanese women aged 27-45…
- Trial name
- NCT04022148
- Testing
- Gardasil
- Volunteers
- 2,800 people, healthy volunteers welcome
- Sponsor
- University of Fukui
Cervical Cancer
HPV Testing In Polish POpulation-based Cervical Cancer Screening Program.
The HIPPO PROJECT is a randomized healthcare study nested in the OCCSP in Poland. This project will assess the performance of the new screening test (HR HPV test) before its implementation in Poland.
- Trial name
- HIPPOPROJECT (NCT04111835)
- Testing
- Offering an alternative cervical cancer screening method - hrHPV molecular testing.
- Where
- Poland
- Volunteers
- 33,000 people
- Sponsor
- Maria Sklodowska-Curie National Research Institute of Oncology
Breast Cancer, Cervical Cancer
Kukui Ahi Navigator Cancer Screening and Treatment Demonstration Project
This Cancer Prevention and Treatment Demonstration Project funded by the Centers of Medicare and Medicaid Services awarded six sites across the United States to develop Patient Navigator Programs to eliminate disparities in the…
- Conditions
- Breast Cancer, Cervical Cancer, Prostate Cancer, Colorectal Cancer
- Trial name
- NCT00379782
- Testing
- Navigation
- Where
- United States
- Volunteers
- 628 people, healthy volunteers welcome
- Sponsor
- Queen's Medical Center
Cervical Cancer, Cervical Intraepithelial Neoplasia
Dry Run of the ScreenUrSelf Trial
The proposed study is the Dry Run preceding the ScreenUrSelf trial.
- Conditions
- Cervical Cancer, Cervical Intraepithelial Neoplasia, Human Papilloma Virus, HPV-Related Cervical Carcinoma
- Trial name
- NCT05996796
- Testing
- Colli-Pee Small Volumes, Evalyn Brush
- Where
- Belgium
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Universiteit Antwerpen
HPV Infection, Cervical Cancer
Clinical Correlation Between Self-collected and Physician-collected HPV Screening Kits
The objective of this study is to validate the of the Evalyn®Brush via self-collection to the standard clinician-collected technique using the BD SurePath™ collection vial and Rovers CombiBrush for detection of Human…
- Trial name
- NCT05679141
- Where
- Canada
- Volunteers
- 344 people, healthy volunteers welcome
- Sponsor
- Switch Health Solutions Inc.
Cervical Cancer, Breast Cancer
Salud en Mis Manos - Breast and Cervical Cancer Prevention and Early Detection - Expansion 1
The purpose is to evaluate implementation of a community-based prevention project aimed at increasing early detection and prevention of breast and cervical cancer through education and navigation and to increase breast and…
- Trial name
- SEMM1 (NCT06082505)
- Testing
- Education, Navigation to clinic
- Where
- United States
- Volunteers
- 8,262 people, healthy volunteers welcome
- Sponsor
- The University of Texas Health Science Center, Houston