Clinical trials: Cervical Cancer Screening
Cervical Dysplasia
Effect of a Childcare Resource on Cervical Cancer Prevention
Aim 1: Determine the prevalence of unmet childcare needs among women with abnormal cervical cancer screening and establish the relevance of childcare as a social determinant of health in the context of cervical dysplasia.
- Trial name
- NCT06086054
- Testing
- Navigation and EMR referral to childcare facility
- Where
- United States
- Volunteers
- 65 people, healthy volunteers welcome
- Sponsor
- University of Texas Southwestern Medical Center
Oropharyngeal Cancer, HPV-Related Carcinoma
A Study Using Human Papillomavirus (HPV) DNA Testing to Detect HPV-Related Oropharyngeal Cancer (OPC)
The researchers think that a blood test (NavDx®) may be able to identify cancer early by looking for circulating DNA from Human Papillomavirus/HPV. Circulating DNA are small pieces of genes that are released into the bloodstream.
- Conditions
- Oropharyngeal Cancer, HPV-Related Carcinoma, HPV Positive Oropharyngeal Squamous Cell Carcinoma
- Trial name
- NCT05814549
- Testing
- NavDx
- Where
- 7 sites in United States
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- Memorial Sloan Kettering Cancer Center
Cervical Cancer
CINtec PLUS Triage in HPV Primary Screening
Prospective study which will recruit participants when they attend for a routine cervical screening. The study will evaluate the use of CINtec PLUS for triage of human papillomavirus (HPV) positive participants in HPV primary…
- Trial name
- NCT03721484
- Testing
- CINtec PLUS
- Where
- United Kingdom
- Volunteers
- 9,800 people, healthy volunteers welcome
- Sponsor
- Western Health and Social Care Trust
Esophageal Cancer, Head and Neck Cancer
Early Detection of Esophageal Squamous Cancer With the Capsule Sponge Device
Esophageal squamous cell carcinoma accounts for ~90% of the nearly half-million annual incident cases of esophageal cancer worldwide.
- Conditions
- Esophageal Cancer, Head and Neck Cancer, Squamous Cell Carcinoma
- Trial name
- ANGELA (NCT06418516)
- Testing
- Capsule-sponge
- Volunteers
- 340 people, healthy volunteers welcome
- Sponsor
- Centre of Postgraduate Medical Education
Hiv, Hpv
Real-world Effectiveness of HPV Vaccine in Women Living With HIV and Its Impact on Cervical Cancer Screening Accuracies
This study will examine both Human papillomavirus (HPV) vaccine effectiveness and Primary high-risk HPV PHS screening triage strategies in women living with HIV (WLHIV) by partnering with the Pediatric HIV/AIDs Cohort Study…
- Trial name
- LiVes-LLC (NCT06144229)
- Testing
- Self-Collection HPV testing kit from Abbott
- Where
- 9 sites in United States
- Volunteers
- 650 people
- Sponsor
- University of California, Los Angeles
Cervical Intraepithelial Neoplasia
A Novel, Low-Cost, Handheld 3D Imaging System for Improved Screening for Cervical Neoplasia in Resource-Limited Settings
The purpose of this study is to evaluate the design and engineering of a new minimally invasive medical imaging device (CervImage™).
- Trial name
- CervImage (NCT06810427)
- Testing
- CervImage device
- Where
- United States
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Carilion Clinic
Cancer of Esophagus
Impedance Spectroscopy in Esophageal Cancer
Detection of early esophageal cancer in surrounding normal tissue can be challenging even for experienced examiners. The early detection is essential to determine the following treatment.
- Trial name
- NCT04046601
- Testing
- impedance
- Where
- Germany
- Volunteers
- 67 people
- Sponsor
- Sana Klinikum Offenbach
Endometrial Cancer, Methylation
Clinical Studies of Endometrial Cytology and Cervical Methylation Assays in Endometrial Cancer Screening and Fertility-Preservation Evaluation
The current study aims to assess high-risk patients using both liquid-based cytology and cervical methylation testing. The results will be compared with the traditional hysteroscopic pathological findings to determine the…
- Conditions
- Endometrial Cancer, Methylation, Cytology, Fertility Preservation
- Trial name
- NCT06672341
- Testing
- Endometrial Cytology Testing, Cervical Methylation Testing
- Volunteers
- 200 people
- Sponsor
- Yulan Ren
Cervical Cancer
Finding Barriers and Designing Solutions to Promote Women s Cancer Screening in South Africa
The primary aim of the study explore drivers of cervical cancer screening and barriers contributing to low screening coverage among women in South Africa.
- Trial name
- FIND (NCT05414097)
- Testing
- Semi-structured focus group discussions - Women, semi-structured focus groups discussions - Men, In-depth key stakeholders interviews
- Where
- South Africa
- Volunteers
- 348 people, healthy volunteers welcome
- Sponsor
- UNC Lineberger Comprehensive Cancer Center
Cervical Cancers, CIN - Cervical Intraepithelial Neoplasia
Primary HPV Self-Collection in Indonesia
The purpose of this study is to implement human papillomavirus (HPV) self-collection in Indonesia.
- Conditions
- Cervical Cancers, CIN - Cervical Intraepithelial Neoplasia, Human Papillomavirus (HPV)
- Trial name
- NCT06942286
- Testing
- HPV Self-Collection
- Where
- 3 sites in Indonesia
- Volunteers
- 8,000 people, healthy volunteers welcome
- Sponsor
- Dharmais National Cancer Center Hospital
Head and Neck Squamous Cell Carcinoma (HNSCC)
Screening Trial of Nivolumab With Image Guided, Stereotactic Body Radiotherapy (SBRT) Versus Nivolumab Alone in Patients With Metastatic Head and Neck Squamous Cell Carcinoma (HNSCC)
Nivolumab is an antibody (a type of human protein) that is designed to boost your body's immune system. It does this by allowing immune cells to grow and fight the cancer.
- Trial name
- NCT02684253
- Testing
- Nivolumab, Stereotactic Body Radiation Therapy (SBRT)
- Where
- 6 sites in United States
- Volunteers
- 65 people
- Sponsor
- Memorial Sloan Kettering Cancer Center
Differentiated Thyroid Cancer (DTC), Robotic Assistance
Robotic Surgery Via Bilateral Axillo-breast Approach for Relatively Low-risk Papillary Thyroid Carcinoma With Lateral Cervical Lymph Node Metastasis: a Safe and Effective Cosmetic Procedure in the Context of Prevalent Thyroid Ultrasound Screening
The goal of this observational study is to learn the efficacy, cosmetic effectiveness and safety of robotic modified radical neck dissection in well-selected cases, through direct comparison with conventional open surgery in…
- Trial name
- NCT07229859
- Where
- China
- Volunteers
- 332 people
- Sponsor
- Ruijin Hospital
Esophageal Cancer, Gastric Cancer
Molecular Assessment for Gastro-Esophageal Cancer
The goal of this minimally invasive interventional study is to learn if oncometabolic biomarkers, detected in the exhaled breath and blood can identify early-stage gastro-oesophageal cancer in patient at risk for…
- Conditions
- Esophageal Cancer, Gastric Cancer, Barrett Esophagus
- Trial name
- MAGEC (NCT06346054)
- Testing
- Breath analysis, Blood analysis
- Where
- Belgium
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- KU Leuven
Cervical Cancer, Cervical Intraepithelial Neoplasia
CASUS: Improved and Quality Assured Collection of First-void Urine
The goal of the overall CASUS project is to develop the first fully molecular integrated cervical cancer screening approach, based on first-void urine as an easily accessible and non-invasive source of biomarkers.
- Conditions
- Cervical Cancer, Cervical Intraepithelial Neoplasia, Human Papilloma Virus, HPV-Related Cervical Carcinoma
- Trial name
- CASUS-WP1 (NCT04480866)
- Testing
- Colli-Pee® (FV5000 and Small Volumes)
- Where
- Belgium
- Volunteers
- 25 people
- Sponsor
- Universiteit Antwerpen
Cervical Cancer Screening
The Use of a Novel Vaginal Speculum for Cervical Cancer Screening in Sunrise Community Health Patients
The specific aim of this research is to determine if the Bouquet Speculum TM , compared to the existing 2-bladed vaginal speculum, provides better visualization of the cervix, is easier for the provider to use and is more…
- Trial name
- NCT06496295
- Testing
- Vaginal Speculum Exam
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Rocky Vista University, LLC
Cervical Cancer, Cervical Intraepithelial Neoplasia
CASUS: Validation for Detection of Precursor Lesions
The goal of the overall CASUS project is to develop the first fully molecular integrated cervical cancer screening approach, based on first-void urine as an easily accessible and non-invasive source of biomarkers.
- Conditions
- Cervical Cancer, Cervical Intraepithelial Neoplasia, Human Papilloma Virus, HPV-Related Cervical Carcinoma
- Trial name
- CASUS-WP4 (NCT04530201)
- Testing
- Colli-Pee Small Volumes (10 mL) device
- Where
- 3 sites in Belgium
- Volunteers
- 332 people
- Sponsor
- Universiteit Antwerpen
Cervical Cancer, Cervical Intraepithelial Neoplasia
Randomized Controlled Trial of Human Papillomavirus Testing in Primary Cervical Cancer Screening
Human papillomavirus (HPV)-based cervical screening is known to increase sensitivity for detection of high-grade cervical intraepithelial neoplasia (CIN).
- Trial name
- SWEDESCREEN (NCT00479375)
- Testing
- Adding Human Papillomavirus testing to organised cervical screening
- Where
- Sweden
- Volunteers
- 12,527 people, healthy volunteers welcome
- Sponsor
- Skane University Hospital
Cervical Neoplasia, Cervical Cancer
Cervical Cancer Screening in HIV Positive and Negative Women in Cambodia
The prevalence of cervical neoplasia in Cambodia is not known. There are no screening programs in place. The investigators plan on introducing a screening program based on WHO criteria and utilizing visualization with acetic…
- Trial name
- NCT02253719
- Testing
- cryotherapy, further biopsy, LEEP, surgery as indicated
- Where
- Cambodia
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Sihanouk Hospital Center of HOPE
HPV Infection, Cervix Cancer
Prevention and Screening Towards Elimination of Cervical Cancer
The research project applies the protocol of the World Health Organisation for screening of cervical cancer, with testing of hrHPV as first screening, followed by Visual Inspection of the cervix with Acetic Acid for…
- Conditions
- HPV Infection, Cervix Cancer, Cervical Dysplasia
- Trial name
- PRESCRIP-TEC (NCT05234112)
- Testing
- Community mobilisation for hrHPV self-testing, hrHPV self-testing, Follow-up after testing
- Where
- Uganda
- Volunteers
- 30,000 people, healthy volunteers welcome
- Sponsor
- University Medical Center Groningen
Oral Cancer
Oral Cancer Screening in Workplace: a Cross-sectional Study
Employees are to be all screened for oral cancer in work place.
- Trial name
- NCT06057857
- Testing
- conventional oral examination
- Where
- Egypt
- Volunteers
- 302 people
- Sponsor
- Cairo University