Clinical trials: Cerebrovascular Disorders, open to volunteers
Stroke, Cerebrovascular Disorders
Mixed Reality and Virtual Reality Technology With Mirror Therapy for Stroke Rehabilitation
The specific study aims will be: 1. To design and develop the hardware and software of the VR+MT and MR+MT systems. 2. To test the feasibility of the VR+MT and MR+MT systems from the patients and to collect the feedback of users…
- Conditions
- Stroke, Cerebrovascular Disorders, Central Nervous System Diseases
- Trial name
- NCT05903235
- Testing
- Virtual Reality-based Mirror Therapy (VR+MT), Mixed Reality-based Mirror Therapy (MR+MT), Traditional Mirror Therapy (MT)
- Where
- Taiwan
- Volunteers
- 45 people
- Sponsor
- Chang Gung Memorial Hospital
Intracerebral Hemorrhage
TrIal of Early Minimally Invasive Catheter Evacuation With Thrombolysis in IntraCerebral Hemorrhage
TIME-ICH (TrIal of early Minimally Invasive catheter Evacuation with thrombolysis in IntraCerebral Hemorrhage) is a multicenter, randomized, adaptive clinical trial comparing best medical management to early minimally invasive…
- Trial name
- TIME-ICH (NCT07187687)
- Testing
- Early Minimally Invasive Surgery with Thrombolysis (eMIST)
- Where
- 70 sites in China
- Volunteers
- 750 people
- Sponsor
- Xuanwu Hospital, Beijing
Brain Disease, Ischemic Attack, Transient
Natural History of Stroke: Cause and Development
The purpose of this study is to learn more about stroke and obtain information that may serve as the basis for future investigations.
- Conditions
- Brain Disease, Ischemic Attack, Transient, Cerebrovascular Accident, Cerebrovascular Disorder
- Trial name
- NCT00009243
- Where
- 3 sites in United States
- Volunteers
- 4,000 people
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
Stroke
Oral and Salivary Biomarkers Associated With Stroke
This observational study aims to investigate associations between oral and salivary biomarkers and stroke. Adults with stroke and healthy controls will undergo clinical oral assessment and unstimulated saliva collection.
- Trial name
- NCT07357155
- Where
- 2 sites in Algeria
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University Hospital Center (CHU) of Constantine, Algeria
Type 2 Diabetes, Coronary Heart Disease
NMR Metabolomics-Based Risk Assessment and Stratified Digital Health Interventions in Middle-Aged Adults (PREMAP)
PREMAP invites residents of the Eloisa region (South Savo, Finland) turning 45, 50, or 55 years of age in 2026 to undergo a blood-based NMR metabolomics risk assessment for five interlinked cardio-renal-metabolic conditions (type…
- Conditions
- Type 2 Diabetes, Coronary Heart Disease, Myocardial Infarction, Cerebrovascular Disease
- Trial name
- PREMAP (NCT07820800)
- Testing
- Digital health interventions
- Where
- Finland
- Volunteers
- 1,400 people, healthy volunteers welcome
- Sponsor
- University of Eastern Finland
Hyperoxia, Hyperoxemia
Hyperoxemia and Oxygen Reserve Index During Neurointerventional Anesthesia
The goal of this observational study is to learn how often high blood oxygen levels (hyperoxemia) occur in adults receiving general anesthesia for planned (elective) neurointerventional procedures, such as brain aneurysm coiling…
- Conditions
- Hyperoxia, Hyperoxemia, Cerebrovascular Disorders, Intracranial Aneurysms
- Trial name
- NCT07859982
- Testing
- Oxygen Reserve Index Monitoring (Observational)
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- Fatih Sultan Mehmet Training and Research Hospital
Exoskeleton Device, Sensory Disorder
Efficacy of Intensive Visual Simulation (IVS) Before Exoskeleton-assisted Step Training in Patients With Hemisensory Syndrome With Brain Injury of Vascular Etiology.
Clinical trial involving a medical device, not intended for CE marking, randomized, blinded to evaluate the efficacy of preparatory treatment with Intensive Visual Simulation 4 (IVS) prior to exoskeleton-assisted (EKSO) step…
- Conditions
- Exoskeleton Device, Sensory Disorder, Brain Injuries, Vascular
- Trial name
- IVS (NCT07860840)
- Testing
- Rehabilitation treatment with IVS before step training using an exoskeleton, Rehabilitation treatment with step training using an exoskeleton
- Where
- Italy
- Volunteers
- 22 people
- Sponsor
- IRCCS Sacro Cuore Don Calabria di Negrar
Stroke
Improving Measurement and Treatment of Post-stroke Neglect
This study examines how to best assess and treat post-stroke neglect. This study will examine the preliminary effects of an innovative intervention (repetitive task-specific practice + transcranial direct current stimulation) for…
- Trial name
- NCT03317860
- Testing
- Active direct current stimulation (tDCS)
- Where
- United States
- Volunteers
- 17 people
- Sponsor
- VA Office of Research and Development
Stroke, Cerebrovascular Disorders
Video Call Assisted Assessment of Acute Stroke
This study aims to investigate whether a live stream video between the on-call neurologist and the emergency medical technicians can increase feasibility and performance of symptom-based prehospital stroke scales.
- Conditions
- Stroke, Cerebrovascular Disorders, Brain Diseases, Nervous System Diseases
- Trial name
- NCT06570681
- Testing
- Video call assisted assessment of acute stroke
- Where
- Denmark
- Volunteers
- 512 people
- Sponsor
- University of Southern Denmark
Stroke, Brain Disease
Screening for Social Determinants of Health (SDOH) and Cognitive Function in Individuals With History of Stroke
Background: Stroke is the fifth leading cause of death in the United States. It is also a leading cause of disability. More than 70% of people who survive strokes have mental impairment or dementia.
- Conditions
- Stroke, Brain Disease, Vascular Diseases, Cerebrovascular Disorder
- Trial name
- NCT06615973
- Where
- United States
- Volunteers
- 450 people
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
Stroke, Chronic Stroke Patients
kTMP-Enhanced Motor Rehabilitation for Chronic Stroke Recovery (KULMINATE) Pilot
kTMP, kilohertz transcutaneous magnetic perturbations, is a low intensity transcranial magnetic stimulation technique that will be used in this study to promote arm/hand rehabilitation in patients who have been disabled by stroke.
- Conditions
- Stroke, Chronic Stroke Patients, Arm Weakness as a Consequence of Stroke
- Trial name
- NCT07631078
- Testing
- kTMP
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- Magnetic Tides
Cerebrovascular Diseases, Lung
Clinical Application of a Low-Dose CBCT AI Model
Cone Beam CT (CBCT) is an imaging modality used in interventional digital subtraction angiography (DSA). It produces three-dimensional images via cone-beam X-ray scanning and computer reconstruction.
- Conditions
- Cerebrovascular Diseases, Lung, Liver
- Trial name
- NCT07845929
- Testing
- DeepPriorCBCT-V2, Clinical standard protocol (Full-radiation-dose CBCT)
- Where
- 5 sites in China
- Volunteers
- 1,380 people
- Sponsor
- Union Hospital, Tongji Medical College, Huazhong University of Science and Technology
Dementia, Postoperative Delirium (POD)
Prediction and Prevention of Postoperative Mortality and Morbidity
This study will contribute to creating a prospective and automated preoperative risk assessment algorithm for predicting 30-day mortality, major adverse cardiac and cerebrovascular events (MACCE), and postoperative neurocognitive…
- Conditions
- Dementia, Postoperative Delirium (POD), Postoperative Neurocognitive Disorder, Major Adverse Cardiac and Cerebrovascular Events
- Trial name
- NCT06042413
- Testing
- Personalized CPC Prehabilitation, Cognitive Training, Meditation
- Where
- 5 sites in United States
- Volunteers
- 1,200 people
- Sponsor
- University of Pittsburgh
Hemodialysis, Cognitive Impairment
Influencing Factors of Cerebrovascular Disease and Cognition in Hemodialysis Patients
In this observational study, the investigators evaluate the influencing factors of cerebrovascular disease and cognition in hemodialysis patients.
- Conditions
- Hemodialysis, Cognitive Impairment, Cerebrovascular Disorders
- Trial name
- NCT04433455
- Where
- China
- Volunteers
- 20 people
- Sponsor
- Huashan Hospital
Psychological Stress, Cardiovascular Diseases
Cerebrovascular Health and Resilience in Midlife
This study examines cardiovascular responses to a brief psychological challenge under laboratory conditions among adult volunteers. The study volunteers are asked to complete two study sessions.
- Conditions
- Psychological Stress, Cardiovascular Diseases, Cerebrovascular Disorders
- Trial name
- CHARM (NCT06029348)
- Testing
- Paced Auditory Serial Addition Task
- Where
- United States
- Volunteers
- 450 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Dysphagia Following Cerebrovascular Accident
Evaluation of Effectiveness of an Interactive Dysphagia Education System for Patients With Stroke
The goal of this clinical trial is to learn if an interactive dysphagia education system can improve swallowing outcomes and quality of life in patients with post-stroke dysphagia.
- Trial name
- NCT07810374
- Testing
- Interactive dysphagia education
- Where
- Taiwan
- Volunteers
- 100 people
- Sponsor
- Mei-Yu Lin
Cardiovascular Diseases, Stroke
Hybrid Stroke Rehab With Mirror Priming
This trial aims to examine the effects of enhanced mirror priming, overcoming the limitations of traditional mirror therapy, to achieve optimization and personalized intervention.
- Conditions
- Cardiovascular Diseases, Stroke, Cerebrovascular Disorders
- Trial name
- NCT07324278
- Testing
- Mirror priming, Conventional therapy
- Where
- Taiwan
- Volunteers
- 81 people
- Sponsor
- I-Shou University
Stroke, Visual Field Defect
Visual Restoration Using Focused Ultrasound Stimulation and Immersive Virtual Reality After Stroke
This research will explore if brain stimulation combined with virtual reality therapy improves visual impairment. The stimulation technique is called low-intensity focused ultrasound stimulation (LIFUS).
- Conditions
- Stroke, Visual Field Defect, Visual Field Defect Following Cerebrovascular Accident, Hemianopia
- Trial name
- LIFU-IVR (NCT06875206)
- Testing
- Low-intensity focused ultrasound, Immersive virtual reality, Inactive Low-intensity focused ultrasound
- Where
- United States
- Volunteers
- 28 people
- Sponsor
- Duke University
Cerebrovascular Disorders
Daphnetin Capsule In the Treatment of VaScular COgnitive Impairment Without Dementia
The purpose of this clinical trial is to understand and evaluate the clinical efficacy and safety of Daphnetin Capsule in patients with vascular cognitive impairment.
- Trial name
- DISCO (NCT06507488)
- Testing
- Daphnetin Capsule
- Where
- China
- Volunteers
- 206 people
- Sponsor
- First People's Hospital of Shenyang
Stroke, Stroke, Acute
PRecisiOn Medicine In StrokE: Evolution of Plasma Brain-Derived Tau in Acute Stroke
The investigators recently identified Brain-derived tau (BD-tau) as a sensitive blood-based biomarker for brain injury in acute ischemic stroke: in patients with acute ischemic stroke, plasma BD-tau was associated with…
- Conditions
- Stroke, Stroke, Acute, Stroke, Ischemic, Cerebrovascular Disorders
- Trial name
- PROMISE-BD-100 (NCT06121336)
- Testing
- Plasma levels of BD-tau
- Where
- Germany
- Volunteers
- 100 people
- Sponsor
- Ludwig-Maximilians - University of Munich