Clinical trials: Cerebral Oxygen Saturation
Ischemic Attack, Transient
Does Positioning Effects on Early Postoperative Cognitive Dysfunction in Laparoscopic Oncological Surgery
Laparoscopic surgery is an alternative to open surgical techniques for reasons such as less blood loss,less need for transfusion, shorter discharge time.
- Trial name
- NCT04714346
- Testing
- no interventions
- Where
- Turkey (Türkiye)
- Volunteers
- 53 people, healthy volunteers welcome
- Sponsor
- Saglik Bilimleri Universitesi
Cerebral Oxygenation
Effect of Left Paratracheal Pressure on Cerebral Oxygenation During General Anesthesia
Left paratracheal pressure (LPP) has been proposed as an alternative to cricoid pressure to reduce the risk of regurgitation during induction of general anesthesia.
- Trial name
- PARANIRS (NCT07778303)
- Testing
- Left Paratracheal Pressure, Cricoid Pressure
- Where
- Belgium
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Clinique Saint-Luc
Intracranial Pressure Increase
Comparison of ONSD and rSO2 Measurements Between General and Spinal Anesthesia in C-Section
General anesthesia and regional anesthesia can be chosen in cesarean operations. Endotracheal intubation and mechanical ventilation are components of general anesthesia.
- Trial name
- NCT04446013
- Testing
- Optic Nerve Sheath Diameter Measurement
- Where
- Turkey (Türkiye)
- Volunteers
- 81 people, healthy volunteers welcome
- Sponsor
- Bagcilar Training and Research Hospital
Ventilation Mode, Pleth Variability Index
Effects of Volume and Pressure-Controlled Ventilation on Cerebral SpO2, PI, and PVI Index in Septoplasty
Objective: This study was designed to evaluate the accuracy of Pleth Variability Index (PVI), Perfusion Index (PI) and Regional Oxygen Saturation (rSO2) in both ventilation modes in patients undergoing septorhinoplasty operation…
- Conditions
- Ventilation Mode, Pleth Variability Index, Perfusion Index, Regional Cerebral Oxygen Saturation
- Trial name
- NCT06407362
- Testing
- Cerebral Oxygen Saturation
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Sanliurfa Mehmet Akif Inan Education and Research Hospital
Oxygen Deficiency
Creatine and GAA for Brain Oxygenation
The main aim of this randomized controlled trial is to evaluate cerebral blood oxygenation after 7-day administration of a creatine-guanidinoacetic acid (GAA) mixture in healthy adults before, during, and after a series of…
- Trial name
- CREGAA-OXY (NCT06371651)
- Testing
- Supplement
- Where
- Serbia
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- University of Novi Sad, Faculty of Sport and Physical Education
Hypotension Drug-Induced, Cerebral Oxygen Saturation
Effect of Controlled Hypotension on Cerebral Oxygen Saturation
For a successful functional endoscopic sinus surgery (FESS), it is crucial to provide effective controlled hypotension to reduce blood loss and provide a relatively blood-free surgical environment to facilitate surgery.
- Trial name
- NCT02967029
- Testing
- Esmolol Hydrochloride, Remifentanil Hydrochloride
- Where
- Turkey (Türkiye)
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Istanbul University
Healthy
Validation of Brain Oxygenation Monitor
A cerebral oximeter is a device that uses light to measure the amount of oxygen within the brain. It is similar to the device that measures the level of oxygen in the tip of the finger, known as a pulse oximeter.
- Trial name
- NCT00815490
- Testing
- Desaturation
- Where
- United States
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Duke University
Baro-reflex Sensitivity, Heart Rate Variability
Low Intensity Exercise in Different Normobaric/Hypobaric Normoxic/Hypoxic Conditions.
The main goal of this project is to investigate how low intensity cycling exercise (1.5W/kg, for 6 minutes) influences cerebral functions, such as: Cerebral blood flow, oxygenation, and other physiological variables in different…
- Conditions
- Baro-reflex Sensitivity, Heart Rate Variability, EEG, Microstates, Cerebral Blood Flow Regulation
- Trial name
- Hypoxia (NCT03439202)
- Testing
- Hypoxia
- Where
- Switzerland
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Fliegerärztliches Institut
Healthy
Nonin 4 Wavelength Cerebral Oximeter Study
A cerebral oximeter is a device that uses light to measure the amount of oxygen within the brain. It is similar to the device that measures the level of oxygen in the tip of the finger, known as a pulse oximeter.
- Trial name
- Nonin4 (NCT01762722)
- Testing
- Reduction of inspired oxygen
- Where
- United States
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- Duke University
Cesarean Section, Pregnancy Related
Brain Oxygenation in Newborns Due to Neuroaksial Methods
Epidural and spinal anesthesia techniques are frequently used all over the world in elective cesarean section operations. To evaluate the effects of epidural and spinal anesthesia techniques applied in cesarean section surgery on…
- Conditions
- Cesarean Section, Pregnancy Related, Cerebral Hypoxia, Anesthesia, Regional
- Trial name
- oxygenation (NCT06316596)
- Testing
- Spinal Anesthesia, Epidural Anesthesia
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Bursa Yuksek Ihtisas Training and Research Hospital
Cognitive Dysfunction, Postoperative Complications
The Effect of Hypotensive Anesthesia on Cognitive Functions in Orthognatic Surgery
The purpose of this study is to evaluate the effects of maintaining adequate cerebral oxygen saturation on patients undergoing orthognathic surgery.
- Trial name
- NCT06925711
- Testing
- Near-Infrared Spectroscopy (NIRS)
- Where
- Turkey (Türkiye)
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Medipol University
Obstructive Sleep Apnea
Vasoactive Hormones and Oxygen Saturation During Apneic Events in Patients With Obstructive Sleep Apnea
The mechanisms involved in development and maintenance of hypertension in obstructive sleep apnea are not clarified. We hypothesize that patients with obstructive sleep apnea have an abnormal level of some vasoactive hormones…
- Trial name
- NCT00438412
- Where
- Denmark
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Regional Hospital Holstebro
Hypovolemia
Cerebral Oximetry in Lower Body Negative Pressure
The study aims to describe hemodynamic effects of lower body negative pressure (LBNP). 1. If and how changes in cerebral oxygen saturation (StO2) measured by near infrared spectroscopy (NIRS) relate to changes in blood flow in…
- Trial name
- NCT03009305
- Testing
- Lower body negative pressure, Continuous positive airway pressure, Positive expiratory pressure
- Where
- Norway
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Oslo University Hospital
Cerebral Tumor, Stroke
Magnetic Resonance Imaging Evaluation of the Tissular Oxygen Saturation in Brain
The purpose of this study is to measure the tissular oxygen saturation in brain by magnetic resonance imaging on subjects and to correlate the results with near infrared spectroscopy measurements.
- Trial name
- GADOXY (NCT02317055)
- Testing
- imaging
- Where
- France
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- University Hospital, Grenoble
Neonatal Cerebral Oxygenation, Cesarean Section
Effects of Spinal Versus General Anesthesia on Neonatal Cerebral Oxygenation During Cesarean Section
This prospective observational study evaluates and compares the effects of spinal and general anesthesia techniques used during elective cesarean section on neonatal cerebral regional oxygen saturation (crSO₂) during the early…
- Trial name
- NEO-OXY-CS (NCT07477093)
- Testing
- No intervention (observational study)
- Where
- Turkey (Türkiye)
- Volunteers
- 49 people, healthy volunteers welcome
- Sponsor
- Akdeniz University Hospital
Anesthesia, Cerebral Blood Flow
Hypertension and Cerebrovascular Hemodynamics in General Anaesthesia
During anesthesia, blood pressure-raising medications are often required to achieve an adequate blood pressure level. However, there is limited knowledge about what constitutes an adequate blood pressure to ensure sufficient…
- Conditions
- Anesthesia, Cerebral Blood Flow, Regional Cerebral Oxygen Saturation, Blood Pressure
- Trial name
- NCT06855407
- Testing
- Blood pressure elevation
- Where
- Sweden
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Umeå University
Impaired Oxygen Delivery, Critically Ill Patient
Non-Invasive Measurement of SjvO2 Using Near Infrared Spectroscopy in Critically Ill Patients
ScvO2 is an important parameter in the management of critically ill patient. The only way to measure it is to have an internal jugular or subclavian central venous catheter.
- Trial name
- NIRS-SCJVO2 (NCT04624009)
- Where
- 2 sites in Switzerland
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- University Hospital, Geneva
Cerebral Hypoxia, Severe Traumatic Brain Injury
Prioritization of Cerebral Deoxygenation in Severe Traumatic Brain Injury and Mortality Benefit.
Severe traumatic brain injury with a decrease in cerebral oximetry is associated with multiple impaired systemic microcirculations, more morbidities, and a higher mortality rate.
- Trial name
- NCT06306950
- Testing
- Near infrared spectroscopy neuromonitor to prevent cerebral desaturation
- Where
- Thailand
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Phramongkutklao College of Medicine and Hospital
Hyperextension Injury of Neck
Effects of Cervical Hyperextension on Cervical Blood Flow, Cerebral Oximetry and Cognitive Functions.
The goal of this observational study is to determine the effects of cervical hyperextension on cerebral oximetry and cognitive functions in healthy individuals without other additional factors such as anesthesia and surgical…
- Trial name
- NCT05576857
- Testing
- Doppler ultrasonography
- Where
- Turkey (Türkiye)
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- Duzce University
SSNHL(Sudden Sensory Neural Hearing Loss)
The Effect of Oxygen Administration on Regional Cerebral Oxygen Saturation (rSO2) in the Non-block Side After Stellate Ganglion Block
Stellate ganglion block (SGB) is known to increase blood flow to the innervation area of the stellate ganglion. Near infrared spectroscopy reflects changes of blood volume and allows continuous, non-invasive, and bedside…
- Trial name
- NCT01532713
- Testing
- oxygen administration
- Where
- South Korea
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Yonsei University