Clinical trials: Cataracts
Cataract
Visual Function With Bilateral AcrySof® ReSTOR® Aspheric SN6AD1
The objective of this study is to prospectively evaluate the visual parameters in a series of patients after phacoemulsification cataract surgery in a series of patients bilaterally implanted with the AcrySof® ReSTOR® Aspheric…
- Trial name
- NCT00710931
- Testing
- AcrySof ReSTOR Aspheric IOL model SN6AD1
- Where
- United States
- Volunteers
- 35 people
- Sponsor
- Alcon Research
Cataract
AcrySof® Bilateral PanOptix(R) Spectacle Freedom and Patient Satisfaction Study
The objective of this study is to assess the spectacle independence of patients receiving the AcrySof® Panoptix® Intraocular lens (IOL) after uneventful cataract surgery.
- Trial name
- NCT04126187
- Testing
- Panoptix
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Gainesville Eye Associates
Aphakia, Presbyopia
Clareon PanOptix Pro vs. Clareon PanOptix - Study A
The purpose of this study is to evaluate the safety and effectiveness of Clareon™ PanOptix™ Pro Trifocal Intraocular Lens (IOL) compared to Clareon™ PanOptix™ Trifocal IOL.
- Trial name
- NCT06400745
- Testing
- CPO Pro IOL, CPO IOL, Cataract surgery
- Where
- 8 sites in United States
- Volunteers
- 87 people
- Sponsor
- Alcon Research
Age-related Cataract, Phacoemulsification
Study to Evaluate the Safety of the Viscoelastic Substance PRO-149, Compared to Healon® EndoCoat.
Pilot, controlled, parallel group, open, randomized clinical trial to evaluate the safety of the viscoelastic substance PRO-149 (sodium hyaluronate 3%) after trans-surgical administration as a device in performing…
- Trial name
- PRO-149 (NCT04702802)
- Testing
- Sodium hyaluronate 3%
- Where
- Mexico
- Volunteers
- 36 people
- Sponsor
- Laboratorios Sophia S.A de C.V.
Cataract
Study of the Femtosecond Laser System as Compared to Continuous Curvilinear Capsulorhexis for Cataract Surgery
The purpose of this study is to evaluate the safety and efficacy of the OptiMedica Femtosecond Laser System to perform surgical maneuvers used in the treatment of subjects with cataracts.
- Trial name
- NCT01069172
- Testing
- FS Laser Surgery, CCC Surgery
- Where
- Dominican Republic
- Volunteers
- 30 people
- Sponsor
- Abbott Medical Optics
Inflammation, Pain
Evaluation of Loteprednol Etabonate Versus Vehicle for the Treatment of Inflammation and Pain Following Cataract Surgery
This study is being conducted to compare the safety and efficacy of loteprednol etabonate to vehicle for the treatment of postoperative inflammation and pain following cataract surgery.
- Trial name
- NCT01060072
- Testing
- Loteprednol etabonate, Vehicle of Loteprednol Etabonate
- Where
- United States
- Volunteers
- 407 people
- Sponsor
- Bausch & Lomb Incorporated
Cataract
Surgeon Experience ReSTOR A +4 Intraocular Lens (IOL)
To collect visual outcome data post AcrySof ReSTOR Aspheric +4 implantation from surgeons throughout the United States.
- Trial name
- NCT00733512
- Testing
- ReSTOR
- Where
- United States
- Volunteers
- 146 people
- Sponsor
- Alcon Research
Cataract
Evaluation of Quality of Vision and Visual Outcomes With Bilateral Implantation of the Clareon PanOptix Intraocular Lens
To evaluate visual outcomes and quality of vision following bilateral implantation of the Clareon PanOptix intraocular lens (IOL) targeted for emmetropia.
- Trial name
- NCT05518539
- Testing
- The Clareon™ PanOptix™ Trifocal (toric and non-toric models)
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Newsom Eye & Laser Center
Unilateral Cataract Extraction, Congenital Cataract
A Randomized Study in Children Ages Birth Through Three Years Undergoing Unilateral Cataract Extraction With or Without Lens Replacement
The purpose of this study is to evaluate the effect of OMS302 compared to phenylephrine when administered in irrigation solution during cataract extraction on intraoperative pupil diameter, acute postoperative pain, and safety in…
- Trial name
- ILR7 (NCT02132312)
- Testing
- OMS302, Phenylephrine HCl
- Where
- 11 sites in United States
- Volunteers
- 78 people
- Sponsor
- Omeros Corporation
Cataract
No Drop Post-Op Cataract Surgery
This study evaluates the effect of Intraocular Phenylephrine/Ketorolac Infusion on Retinal Thickness and Macular Edema in Cataract Surgery.
- Trial name
- NCT03864133
- Testing
- Omidria
- Where
- United States
- Volunteers
- 94 people
- Sponsor
- Wake Forest University Health Sciences
Pain, Inflammation
Safety/Efficacy of Nepafenac Punctal Plug Delivery System Compared to Placebo to Control Ocular Pain/Inflammation After Cataract
This is a Phase 2, multi-center, randomized, parallel-arm, double-masked, placebo-controlled study. One (1) to 2 days prior to their scheduled cataract surgery, each study subject will be randomized (2:1) in to one of two…
- Trial name
- NCT03496467
- Testing
- Nepafenac PPDS
- Where
- 3 sites in United States
- Volunteers
- 56 people
- Sponsor
- Mati Therapeutics Inc.
Primary Open Angle Glaucoma (POAG)
Safety and Performance Study of the ARGOS-IO (Intraocular) System in Patients With Primary Open Angle Glaucoma (POAG)
The purpose of this study is to evaluate the safety and performance of the ARGOS-IO system in patients with POAG and indicated cataract surgery.
- Trial name
- NCT02434692
- Testing
- ARGOS-IO system
- Where
- 11 sites in Germany
- Volunteers
- 24 people
- Sponsor
- Implandata Ophthalmic Products GmbH
Childhood Cataract
Infrared Choroidal Reflectance Camera for the Detection of Childhood Cataract
Sensitivity and specificity of current screening methods for childhood cataracts is poor. This results in delayed diagnosis and management which can decrease the visual prognosis following cataract surgery.
- Trial name
- NCT03035292
- Testing
- Red-reflex assessment, Infrared-reflex assessment
- Where
- United Kingdom
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Cambridge University Hospitals NHS Foundation Trust
Inflammation, Pain
Loteprednol Etabonate Ophthalmic Gel for the Treatment of Ocular Inflammation and Pain Following Cataract Surgery
The objective of this study is to evaluate the safety and efficacy of loteprednol etabonate (LE) ophthalmic gel, 0.38% (BID)
- Conditions
- Inflammation, Pain, Cataract
- Trial name
- NCT02208297
- Testing
- Loteprednol Etabonate Gel (BID), Vehicle Gel (BID)
- Where
- United States
- Volunteers
- 326 people
- Sponsor
- Bausch & Lomb Incorporated
Aphakia, Presbyopia
Clareon PanOptix Pro vs. Clareon PanOptix - Study B
The purpose of this study is to evaluate the safety and effectiveness of Clareon™ PanOptix™ Pro Trifocal Intraocular Lens (IOL) compared to Clareon™ PanOptix™ Trifocal IOL.
- Trial name
- NCT06401551
- Testing
- CPO Pro IOL, CPO IOL, Cataract Surgery
- Where
- 8 sites in United States
- Volunteers
- 71 people
- Sponsor
- Alcon Research
Inflammation, Pseudophakia
Clinical Outcomes of Bromday (Bromfenac Ophthalmic Solution) 0.09% QD vs. Nevanac (Nepafenac Ophthalmic Suspension) 0.1%
This is a single-center, randomized, investigator-masked, parallel group, and active-comparator controlled study investigating the clinical outcomes for visual acuity and macular thickness after treatment with Bromday (bromfenac…
- Trial name
- NCT01310127
- Testing
- Bromfenac, Nepafenac
- Volunteers
- 23 people
- Sponsor
- Toyos Clinic
Cataracts
A Comparison of Prophylactic Antibacterial Efficacy of Besivance vs. VIGAMOX Prior to Cataract Surgery
To compare antibacterial efficacy of Besivance versus VIGAMOX for decreasing bacteria of the conjunctiva and lid margins in cataract patients prior to surgery after both 1 hour and 3 days of treatment.
- Trial name
- NCT01296542
- Testing
- Moxifloxacin Ophthalmic, Besifloxacin Ophthalmic
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Bucci Laser Vision Institute
Cataract
Clinical Investigation of the Bacterially-Derived Healon5 Ophthalmic Viscosurgical Device (OVD)
Prospective, multicenter, paired-eye, randomized, masked, clinical trial of the bacterially-derived Healon5 OVD versus the currently available Healon5 OVD control.
- Trial name
- NCT02782676
- Testing
- Investigational Healon5 OVD, Healon5 OVD
- Volunteers
- 241 people, healthy volunteers welcome
- Sponsor
- Abbott Medical Optics
Aphakia, Cataract
Single Center Exploratory Study To Evaluate The Use Of The RxSight Light Adjustable Lens (LAL) And The Light Delivery Device (LDD) To Improve Visual Outcomes
The objective of this study is to evaluate, for the visual correction of aphakia, whether the RxSight Light Adjustable Lens (LAL) and Light Delivery Device (LDD) can be used to improve visual outcomes after performing adjustments…
- Trial name
- NCT04529616
- Testing
- Light Adjustable lens (LAL) and Light Delivery Device (LDD)
- Where
- Mexico
- Volunteers
- 79 people
- Sponsor
- RxSight, Inc.
Cataract
Clinical Investigation of the Next-Generation Intraocular Lens
This study is a 6-month, prospective, multicenter, bilateral, randomized clinical investigation of the TECNIS Model ZHR00 and Model ZQR00 IOLs versus the TECNIS Symfony control IOL.
- Trial name
- NCT03111550
- Testing
- Investigational Intraocular Lens Device #1: TECNIS Model ZHR00, Investigational Intraocular Lens Device #2: TECNIS Model ZQR00, TECNIS Symfony® Extended Range of Vision Intraocular Lens: Model ZXR00
- Where
- 12 sites in United States
- Volunteers
- 242 people
- Sponsor
- Abbott Medical Optics