Clinical trials: Cataract Senile
Cataract Senile
Anterior Chamber Illumination in Cataract Surgery for Eyes With Poor Red Reflex
With a poor red reflex, it is difficult to see the anterior capsule and continuous curvilinear capsulorhexis (CCC) margin, sometimes resulting in decentered CCC or radial tearing of the anterior capsule.
- Trial name
- NCT04220138
- Testing
- Anterior chamber illumination in cataract surgery
- Where
- Egypt
- Volunteers
- 53 people
- Sponsor
- University of Alexandria
Cataract Senile
Cataract Surgery In Patients With Advanced Age
This study evaluates and compares clinical outcomes of < 85 and ≥ 85 year old patients who underwent cataract surgeries.
- Trial name
- NCT04140383
- Testing
- Cataract Surgery
- Where
- Turkey (Türkiye)
- Volunteers
- 152 people
- Sponsor
- Sakarya University
Glaucoma, Cataract Senile
Effect of Presbyopic Correction Lens on Humphrey Visual Field Testing in Patients With Multifocal Intraocular Lens
Purpose of this study was to evaluate the effect of presbyopic correction lens on Humphrey visual field (HVF) testing in patients with 2 models of multifocal intraocular lens (MIOL) both with and without glaucoma.
- Trial name
- NCT05220007
- Testing
- Humphrey visual field testing
- Where
- Thailand
- Volunteers
- 71 people, healthy volunteers welcome
- Sponsor
- Siriraj Hospital
Intraocular Pressure, Cataracts Senile
Intraocular Pressure Variation by Pneumatic Tonometer Before and After Phacoemulsification
The objective of this study is to evaluate the IOP variation before and 30 days after performing phacoemulsification through pneumatic tonometry, in addition to evaluating the factors possibly related to this variation.
- Trial name
- IPOFACO (NCT03016507)
- Where
- Brazil
- Volunteers
- 100 people
- Sponsor
- VER Excelência em Oftalmologia
Cataract Senile
Prospective Evaluation of an Hydrophilic Acrylic Intraocular Lens
Evaluation of the clinical safety and effectiveness of an hydrophilic acrylic intraocular lens
- Trial name
- UVEA 809 (NCT04907500)
- Testing
- Intraocular lens
- Where
- Romania
- Volunteers
- 387 people
- Sponsor
- Carl Zeiss Meditec AG
Cataract
The Pathogenesis of Human Senile Cataract
To study the pathological mechanism of cataract by genomics, transcriptomics, and proteomics.
- Trial name
- NCT03907358
- Testing
- phacoemulsification
- Where
- China
- Volunteers
- 20 people
- Sponsor
- Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine
Cataract Senile
Study to Confirm Safety and Performance of a New Multifocal IOL
Prospective, non-comparative, multicenter study on medical device with 12 months follow-up.
- Trial name
- NCT06247683
- Testing
- trifocal intraocular lens
- Where
- 11 sites in Czechia, Germany and 1 more
- Volunteers
- 135 people
- Sponsor
- Carl Zeiss Meditec AG
Age-related Cataract
EDOF and Multifocal IOL Study
The investigational devices are approved intraocular lenses (IOLs) intended to be implanted after phacoemulsification in individuals suffering from age-related cataract with the need of cataract surgery.
- Trial name
- NCT05573529
- Testing
- phacoemulsification and intraocular lens implantation, intraocular lens implantation
- Where
- Austria
- Volunteers
- 50 people
- Sponsor
- Medical University of Vienna
Cataract
Neural Compensation, Visual Function and Visual Quality After Monofocal or Multifocal Intraocular Lens Implantation
Multifocal intraocular lenses (MIOLs) provide enhanced far and near visual acuity, but they can bring about halos and glare, which are caused by design deficiencies of the IOLs.
- Trial name
- NCT02644720
- Testing
- multifocal intraocular lens implantation, monofocal intraocular lens implantation, Dexamethasone
- Where
- China
- Volunteers
- 50 people
- Sponsor
- Sun Yat-sen University
Cataract Senile, Astigmatism
Accuracy of Topography Guided Automatic Marking of the Intraocular Lens (IOL) -Axis
In cataract surgery, the opaque lens is replaced by an artificial intraocular lens. The procedure also allows for correction of an refractive error such as myopia, hyperopia or astigmatism.
- Trial name
- NCT05750862
- Testing
- Marking of the intended axis of IOL-Implantation manually with an ink and marking device on the surface of the eye
- Where
- Switzerland
- Volunteers
- 30 people
- Sponsor
- Frank Bochmann
Cataract Senile
Study on Visual Performance of a Monofocal Intraocular Lens
Retrospective/Prospective Study on Visual Performance of a Monofocal Intraocular Lens (IOL). The objective is to compare best corrected distance visual acuity (CDVA) between 1-3-month and 12- month follow-up.
- Trial name
- NCT04740788
- Testing
- Monofocal IOL
- Where
- Austria
- Volunteers
- 44 people
- Sponsor
- Carl Zeiss Meditec AG
Cataract Senile
Evaluating App-Based Vision Testing (WHOeyes) Combined With the Questionnaire as a Substitute for One-Week Postoperative In-Clinic Follow-Up in Age-Related Cataract Patients: A Multi-center Randomized Controlled Trial
The goal of this clinical trial is to learn if an app-based vision testing (WHOeyes) combined with a questionnaire can recognize those who have to go back to the hospital, and thus replace the in-clinic 1-week review after an…
- Trial name
- NCT06429527
- Testing
- WHOeyes combined with a questionnaire.
- Where
- China
- Volunteers
- 334 people
- Sponsor
- Zhongshan Ophthalmic Center, Sun Yat-sen University
Cataract Senile, Intraocular Lens Complication
Visual Outcomes Following Bilateral Implantation of the Vivity Toric Intraocular Lens
The objective of this study was to evaluate the clinical and patient reported outcomes after bilateral implantation of the AcrySof™ IQ Vivity™ Toric intraocular lens.
- Trial name
- NCT06196593
- Testing
- AcrySof™ IQ Vivity™ Toric intraocular lens
- Where
- Malaysia
- Volunteers
- 30 people
- Sponsor
- LEC Eye Centre
Cataract Senile, Endophthalmitis
Postoperative Safety Outcomes of Intraoperative Intracameral Preservative-Free Moxifloxacin Versus Levofloxacin
Comparative safety study of intracameral levofloxacin versus moxifloxacin for postoperative infection prophylaxis
- Conditions
- Cataract Senile, Endophthalmitis, Antibiotic Side Effect, Safety Issues
- Trial name
- NCT04403334
- Testing
- Levofloxacin Ophthalmic, Moxifloxacin Ophthalmic
- Where
- Philippines
- Volunteers
- 114 people, healthy volunteers welcome
- Sponsor
- Peregrine Eye and Laser Institute
Senile Cataract, Epiretinal Membrane
Clareon Intraocular Lens Stability in Vitrectomy Patients: CLOVE Study
This prospective randomized controlled trial will be conducted to investigate Clareon intraocular lens (IOL) stability in vitrectomy patients. The investigator plans to target the patients undergoing cataract surgery.
- Conditions
- Senile Cataract, Epiretinal Membrane, Vitreous Hemorrhage
- Trial name
- NCT06383754
- Testing
- Clareon, Tecnis 1
- Where
- Hong Kong
- Volunteers
- 50 people
- Sponsor
- The University of Hong Kong
Age Related Cataracts
A Multicenter, Randomized, Double-Masked, Placebo-Controlled Pilot Study to Evaluate the Efficacy and Safety of ZOC2017217 in Subjects With Age-Related Cataract
This is a multicenter, randomized, double-masked, placebo-controlled pilot study conducted in the United States (US) in subjects with age-related cataract in one or both eyes.
- Trial name
- NCT07395986
- Testing
- 0.4% ZOC2017217, Control
- Where
- 21 sites in United States
- Volunteers
- 8 people
- Sponsor
- Ocusun Ophthalmic Pharmaceutical (Guangzhou) Co., Ltd.
Cataract
Small RNA tRF-31 Changes in Patients With Age-Related Cataract
The goal of this observational study is to evaluate the expression characteristics and clinical relevance of the tRF-31/HIPK2 signaling axis in adults over 18 years old with age-related cataract (ARC).
- Trial name
- NCT07672899
- Testing
- Biospecimen collection (Anterior lens capsule)
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Age-related Cataract
Dysfunctional Lens Index Serves as a Novel Surgery Decision Maker for Age-related Cataracts
To study the correlations among the dysfunctional lens index (DLI), Lens Opacities Classification System III (LOCS III) nuclear opalescence grading score, preoperative corrected distance visual acuity (CDVA), the objective…
- Trial name
- NCT03340389
- Testing
- a ray-tracing aberrometry
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Wenzhou Medical University
Age-related Cataract
Metabo-lipidomics of the Ocular Surface for Cataract Surgery
Cataract is the world's leading cause of blindness, the treatment of which, exclusively surgical, offers excellent results in terms of visual recovery.
- Trial name
- CATARACTOMIQUE (NCT05802550)
- Testing
- Ocular Surface Disease Index, Interferometry, Oxford score
- Where
- France
- Volunteers
- 100 people
- Sponsor
- University Hospital, Tours
Age-related Cataract, Phacoemulsification
Study to Evaluate the Safety of the Viscoelastic Substance PRO-149, Compared to Healon® EndoCoat.
Pilot, controlled, parallel group, open, randomized clinical trial to evaluate the safety of the viscoelastic substance PRO-149 (sodium hyaluronate 3%) after trans-surgical administration as a device in performing…
- Trial name
- PRO-149 (NCT04702802)
- Testing
- Sodium hyaluronate 3%
- Where
- Mexico
- Volunteers
- 36 people
- Sponsor
- Laboratorios Sophia S.A de C.V.