Clinical trials: Cataract
Aphakia
Clinical Study of a UV-Absorbing Acrylic Posterior Chamber Intraocular Lens
The purpose of this study is to assess the safety and efficacy of the HMY Model YA-60BB Intraocular Lens (IOL) when implanted in the posterior chamber of the human eye for the optical correction of aphakia following cataract…
- Trial name
- HMY (NCT00625313)
- Testing
- HMY Model YA-60BB IOL
- Where
- United States
- Volunteers
- 617 people, healthy volunteers welcome
- Sponsor
- Hoya Surgical Optics, Inc.
Cataract, Myopia
VCSEL Based Optical Swept Source Biometry
Optical interferometric biometry is a non-invasive and highly precise method for measuring eye length and intraocular distances. The method already exists as commercial devices (e.g. IOLMaster, Carl Zeiss Meditec AG).
- Trial name
- VBOB (NCT06551480)
- Testing
- Biometry
- Where
- Austria
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Rainer Leitgeb
Cataract
Clinical Evaluation of the One-Piece Tecnis Multifocal Intraocular Lens (IOL)
The purpose of this study is to evaluate near vision of the One-Piece Tecnis Multifocal lens (ZMB00) vs. the One-piece Tecnis monofocal lens (ZCB00)and additionally evaluate general postoperative outcomes of the One-Piece Tecnis…
- Trial name
- NCT01210807
- Testing
- One-Piece Tecnis Multifocal IOL, One-Piece Tecnis monofocal IOL, Model ZCB00
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Abbott Medical Optics
Primary Open Angle Glaucoma
Electroretinogram and Retinal Vascular Changes After Cataract Surgery
To compare electrophysiological and Optical coherence tomography angiography of optic disc and macula changes after uneventful phacoemulsification between normal and cataractus patients with primary open angle glaucoma.
- Trial name
- NCT05871034
- Testing
- phacoemulsification
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Sohag University
Cataract
Conscious Sedation Efficacy of the MKO Melt (Midazolam, Ketamine, Ondansetron)
The investigators hypothesized that the combination of Valium, Tramadol and Zofran is superior to the substantially more expensive MKO melt in patient satisfaction after cataract surgery.
- Trial name
- NCT03653520
- Testing
- Diazepam, Tramadol, Ondansetron
- Where
- United States
- Volunteers
- 651 people, healthy volunteers welcome
- Sponsor
- Avanti Anesthesia
Cataract
Clinical Results of Asqelio Trifocal Toric Diffractive Intraocular Lens
The goal of this observational prospective clinical study is to learn about the clinical outcomes three months after binocular implantation of Asqelio Trifocal Toric IOL in 30 patients submitted to cataract surgery following…
- Trial name
- NCT06190925
- Where
- Spain
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- AST Products, Inc.
Cataract
Lenstec Tetraflex Accommodating Posterior Chamber Intraocular Lens (IOL) Clinical Investigation
The purpose of the following clinical protocol is to evaluate the safety and effectiveness of the Lenstec Tetraflex Accommodating Posterior Chamber Intraocular Lens (IOL) for the protocol inclusion/exclusion criteria.
- Trial name
- NCT00969371
- Testing
- posterior chamber IOL implantation, Experimental TetraFlex Study IOL
- Volunteers
- 470 people, healthy volunteers welcome
- Sponsor
- Lenstec Incorporated
Cataract, Presbyopia
Clinical Trial With PRECIZON Presbyopic
The purpose of this clinical trial is to evaluate the effectiveness of the PRECIZON Presbyopic.
- Trial name
- NCT02409771
- Testing
- PRECIZON Presbyopic
- Where
- 6 sites in Belgium, Germany and 3 more
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Ophtec BV
Cystoid Macular Edema Following Cataract Surgery
CME With Different Fluidic Parameters
Understanding and modulating fluid parameters is an important, but often overlooked aspect of phacoemulsification. In a previous study we compared the impact of using high fluid parameters versus low fluidic parameters on…
- Trial name
- NCT01385852
- Testing
- microcoaxial phacoemulsification
- Where
- India
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Iladevi Cataract and IOL Research Center
Blood Coagulation Disorders
The Effect of Voltaren-ophtha 0.1% Eye Drops on INR Levels (International Normalized Ratio) in Patients Taking Warfarin
A prospective study intended to examine the effect of topical Voltaren-Ophtha 0.1% eye drops after cataract surgery on INR levels (international normalized ratio) in patients taking warfarin.
- Trial name
- NCT02782338
- Testing
- Voltaren ophtha 0.1%
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Wolfson Medical Center
Surgery-Complications, Cataract
Improvement of the Safety of Care in Cataract Surgery Teaching on Eyesi Simulator (E3CAPS)
The aim of this project is to reduce the risks of cataract surgery using the EyeSi simulator Axis 1: to model the learning curve of novice residents in Ophthalmology who follow the training program recommended by the "Collège des…
- Trial name
- E3CAPS (NCT05722080)
- Testing
- Eyesi simulator, Sleep deprivation
- Where
- 2 sites in France
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Nantes University Hospital
Congenital Cataract
Electrophysiology in Congenital Cataract After Lensectomy and Anterior
In this prospective study , a cohort of 91 eyes with congenital cataract and 25 eyes normal eyes from Wenzhou medical university was erolled.91 eyes with congenital cataract was after lensectomy and anterior vitrectomy as test…
- Trial name
- NCT04427748
- Where
- China
- Volunteers
- 116 people, healthy volunteers welcome
- Sponsor
- Wenzhou Medical University
Macular Holes, Epiretinal Membrane
Intraoperative OCT Guidance of Intraocular Surgery II
The overall five-year goals of the project are to develop novel technology to provide actionable new information through provision of live volumetric imaging during surgery, improving surgical practice and outcomes.
- Conditions
- Macular Holes, Epiretinal Membrane, Diabetic Retinopathy, Retinal Detachment
- Trial name
- MIOCT (NCT03713268)
- Testing
- Microscope integrated optical coherence tomography
- Where
- United States
- Volunteers
- 262 people, healthy volunteers welcome
- Sponsor
- Duke University
Diabetic Macular Edema, Cataract
Steroid vs. Anti-vascular Endothelial Growth Factor for Diabetic Macular Edema Prior to Phacoemulsification
The primary objective of this study is to compare the efficacy of antecedent intravitreal anti-vascular endothelial growth factor therapy vs.
- Trial name
- STAMP (NCT03832179)
- Testing
- Bevacizumab, Ranibizumab, Aflibercept
- Where
- United States
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Bay Area Retina Associates
Cataract
Non-genetic Risk Factors of Congenital Cataracts
Prevention and treatment of the reversible childhood blindness, including congenital cataracts (CC), has been listed as a significant component of the international programme "VISION 2020 - the Right to Sight" launched by WHO in…
- Trial name
- NCT03215186
- Testing
- observational study
- Where
- China
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- Sun Yat-sen University
Cataract, Astigmatism
A Trial of Toric Versus Non-toric Intraocular Lenses in Phacoemulsification Cataract Surgery
This is a randomised controlled trial that formally compares intra-ocular lenses, which can be used in cataract surgery, one of which is the standard 'monofocal' lens, and the other is the newer toric lens which can correct…
- Trial name
- NCT01712503
- Testing
- Phacoemulsfication cataract surgery and intra-ocular lens implant
- Where
- United Kingdom
- Volunteers
- 190 people, healthy volunteers welcome
- Sponsor
- Western Sussex Hospitals NHS Trust
Cataract Surgery
The Effect of Hand Massage Applied Before Cataract Surgery on Anxiety, Surgical Fear, Pain and Physiological Parameters
ABSTRACT Objective: The research was conducted as a prospective randomized controlled experimental study to determine the effect of hand massage applied before cataract surgery on anxiety, surgical fear, pain and physiological…
- Trial name
- NCT05232513
- Testing
- Hand massage
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- TC Erciyes University
Cataract, Lens Opacities
Clinical Outcomes of MICROPURE and PodEye Monofocal Intraocular Lenses
Prospective, non-randomised, open, controlled, single-center post-market clinical follow study about Micropure 1.2.3. and PODEYE intraocular lenses.
- Trial name
- PHY1803 (NCT03796624)
- Testing
- Micropure 1.2.3., PODEYE
- Where
- Czechia
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- Beaver-Visitec International, Inc.
Cataracts, Presbyopia
Clinical Evaluation of the Lenstec SBL-3 Multifocal Intraocular Lens
The purpose of this study is to evaluate the safety and performance of the SBL-3 intraocular lens.
- Trial name
- NCT02487160
- Testing
- SBL-3 multifocal intraocular lens, Control monofocal intraocular lens
- Where
- 13 sites in United States
- Volunteers
- 499 people, healthy volunteers welcome
- Sponsor
- Lenstec Incorporated
Cataract
Performance of a Hydrophilic and a Hydrophobic Intraocular Lens of Similar Design
Comparison of the capsular bag performance of the RayOne Hydrophobic Aspheric with the RayOne Aspheric
- Trial name
- NCT03955796
- Testing
- Hydrophobic IOL, Non-hydrophobic IOL
- Where
- Austria
- Volunteers
- healthy volunteers welcome
- Sponsor
- Prim. Prof. Dr. Oliver Findl, MBA